Works by Huang, Xiaozhu

Results: 25

Integrin α2β1 regulates collagen I tethering to modulate hyperresponsiveness in reactive airway disease models.

Published in:

2021

By:

Sean Liu;
Uyen Ngo;
Xin-Zi Tang;
Xin Ren;
Wenli Qiu;
Xiaozhu Huang;
DeGrado, William;
Allen, Christopher D. C.;
Hyunil Jo;
Sheppard, Dean;
Sundaram, Aparna B.;
Liu, Sean;
Ngo, Uyen;
Tang, Xin-Zi;
Ren, Xin;
Qiu, Wenli;
Huang, Xiaozhu;
Allen, Christopher Dc;
Jo, Hyunil

Publication type:

journal article

Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma.

Published in:

2017

By:

Sundaram, Aparna;
Chun Chen;
Khalifeh-Soltani, Amin;
Atakilit, Amha;
Xin Ren;
Wenli Qiu;
Hyunil Jo;
DeGrado, William;
Xiaozhu Huang;
Sheppard, Dean;
Chen, Chun;
Ren, Xin;
Qiu, Wenli;
Jo, Hyunil;
Huang, Xiaozhu

Publication type:

journal article

IL-17A produced by ?? T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction.

Published in:

Nature Medicine, 2012, v. 18, n. 4, p. 547, doi. 10.1038/nm.2684

By:

Kudo, Makoto;
Melton, Andrew C;
Chen, Chun;
Engler, Mary B;
Huang, Katherine E;
Ren, Xin;
Wang, Yanli;
Bernstein, Xin;
Li, John T;
Atabai, Kamran;
Huang, Xiaozhu;
Sheppard, Dean

Publication type:

Article

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma.

Published in:

Nature Medicine, 2002, v. 8, n. 8, p. 885, doi. 10.1038/nm734

By:

Kuperman, Douglas A.;
Huang, Xiaozhu;
Koth, Laura L.;
Chang, Grace H.;
Dolganov, Gregory M.;
Zhu, Zhou;
Elias, Jack A.;
Sheppard, Dean;
Erle, David J.

Publication type:

Article

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins.

Published in:

Nature Medicine, 2002, v. 8, n. 1, p. 27, doi. 10.1038/nm0102-27

By:

Reynolds, Louise E.;
Wyder, Lorenza;
Lively, Julie C.;
Taverna, Daniela;
Robinson, Stephen D.;
Huang, Xiaozhu;
Sheppard, Dean;
Hynes, Richard O.;
Hodivala-Dilke, Kairbaan M.

Publication type:

Article

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061961

By:

Barron, Luke;
Smith, Amber M.;
El Kasmi, Karim C.;
Qualls, Joseph E.;
Huang, Xiaozhu;
Cheever, Allen;
Borthwick, Lee A.;
Wilson, Mark S.;
Murray, Peter J.;
Wynn, Thomas A.

Publication type:

Article

Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.

Published in:

2009

By:

Park SW;
Verhaeghe C;
Nguyenvu LT;
Barbeau R;
Eisley CJ;
Nakagami Y;
Huang X;
Woodruff PG;
Fahy JV;
Erle DJ;
Park, Sung-Woo;
Verhaeghe, Catherine;
Nguyenvu, Louis T;
Barbeau, Rebecca;
Eisley, Christopher J;
Nakagami, Yasuhiro;
Huang, Xiaozhu;
Woodruff, Prescott G;
Fahy, John V;
Erle, David J

Publication type:

journal article

The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 2037, doi. 10.1172/JCI66397

By:

Tamiko R. Katsumoto;
Makoto Kudo;
Chun Chen;
Sundaram, Aparna;
Callahan, Elliott C.;
Jing W. Zhu;
Lin, Joseph;
Rosen, Connor E.;
Manz, Boryana N.;
Jae W. Lee;
Matthay, Michael A.;
Xiaozhu Huang;
Sheppard, Dean;
Weiss, Arthur

Publication type:

Article

Integrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 8, p. 2916, doi. 10.1172/JCI60387

By:

Chun Chen;
Kudo, Makoto;
Rutaganira, Florentine;
Takano, Hiromi;
Lee, Candace;
Atakilit, Amha;
Robinett, Kathryn S.;
Uede, Toshimitsu;
Wolters, Paul J.;
Shokat, Kevan M.;
Xiaozhu Huang;
Sheppard, Dean

Publication type:

Article

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 2, p. 748, doi. 10.1172/JCI58815

By:

Sugimoto, Kotaro;
Kudo, Makoto;
Sundaram, Aparna;
Xin Ren;
Huang, Katherine;
Bernstein, Xin;
Yanli Wang;
Raymond, Wilfred W.;
Erle, David J.;
Åbrink, Magnus;
Caughey, George H.;
Xiaozhu Huang;
Sheppard, Dean

Publication type:

Article

Characterization of integrin β6 and thrombospondin-1 double-null mice.

Published in:

Journal of Cellular & Molecular Medicine, 2005, v. 9, n. 2, p. 421, doi. 10.1111/j.1582-4934.2005.tb00367.x

By:

Ludlow, Anna;
Yee, Karen O.;
Lipman, Ruth;
Bronson, R.;
Weinreb, P.;
Huang, Xiaozhu;
Sheppard, D.;
Lawler, J.

Publication type:

Article

Mice Lacking the Integrin β5 Subunit Have Accelerated Osteoclast Maturation and Increased Activity in the Estrogen-Deficient State.

Published in:

Journal of Bone & Mineral Research, 2005, v. 20, n. 1, p. 58, doi. 10.1359/JBMR.041017

By:

Lane, Nancy E;
Yao, Wei;
Nakamura, Mary C;
Humphrey, Mary Beth;
Kimmel, Donald;
Huang, Xiaozhu;
Sheppard, Dean;
Ross, F Patrick;
Teitelbaum, Steven L

Publication type:

Article

Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2.

Published in:

Respiratory Research, 2004, v. 5, p. 1, doi. 10.1186/1465-9921-5-12

By:

Koth, Laura L.;
Rodriguez, Madeleine W.;
Xin Liu Bernstein;
Chan, Salina;
Xiaozhu Huang;
Charo, Israel F.;
Rollins, Barrett J.;
Erle, David J.

Publication type:

Article

ADAM33 Is Not Essential for Growth and Development and Does Not Modulate Allergic Asthma in Mice.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 18, p. 19, doi. 10.1128/MCB.00646-06

By:

Chun Chen;
Xiaozhu Huang;
Sheppard, Dean

Publication type:

Article

IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 11, p. 4895, doi. 10.1172/JCI76658

By:

Bhattacharya, Mallar;
Sundaram, Aparna;
Kudo, Makoto;
Farmer, Jessica;
Ganesan, Previn;
Khalifeh-Soltani, Amin;
Arjomandi, Mehrdad;
Atabai, Kamran;
Huang, Xiaozhu;
Sheppard, Dean

Publication type:

Article

Sol-Gel Synthesis and Sensing Study of Perovskite CaCu 3 Ti 4 O 12 Nanopowders.

Published in:

Integrated Ferroelectrics, 2011, v. 129, n. 1, p. 188, doi. 10.1080/10584587.2011.576948

By:

Tian, Yang;
Zhang, Xiaojie;
Yang, Yiyi;
Liu, Zhen;
Huang, Xiaozhu

Publication type:

Article

Role of Organic Cation Transporter 1, OCT1 in the Pharmacokinetics and Toxicity of cis-Diammine(pyridine)chloroplatinum(II) and Oxaliplatin in Mice.

Published in:

Pharmaceutical Research, 2011, v. 28, n. 3, p. 610, doi. 10.1007/s11095-010-0312-6

By:

Li, Shuanglian;
Chen, Ying;
Zhang, Shuzhong;
More, Swati;
Huang, Xiaozhu;
Giacomini, Kathleen

Publication type:

Article

AGR2 Is Induced in Asthma and Promotes Allergen-Induced Mucin Overproduction.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2012, v. 47, n. 2, p. 178, doi. 10.1165/rcmb.2011-0421OC

By:

Schroeder, Bradley W.;
Verhaeghe, Catherine;
Park, Sung-Woo;
Nguyenvu, Louis T.;
Xiaozhu Huang;
Guohua Zhen;
Erle, David J.

Publication type:

Article

Expression Profiling Identifies Klf15 as a Glucocorticoid Target That Regulates Airway Hyperresponsiveness.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2011, v. 45, n. 3, p. 642, doi. 10.1165/rcmb.2010-0369OC

By:

Masuno, Kiriko;
Haldar, Saptarsi M.;
Jeyaraj, Darwin;
Mailloux, Christina M.;
Xiaozhu Huang;
Panettieri Jr, Rey A.;
Jain, Mukesh K.;
Gerber, Anthony N.

Publication type:

Article

Loss of integrin avB6-mediated TGF-B activation causes Mmp12-dependent emphysema.

Published in:

Nature, 2003, v. 422, n. 6928, p. 169, doi. 10.1038/nature01413

By:

Morris, David G.;
Huang, Xiaozhu;
Kaminski, Naftali;
Wang, Yanli;
Shapiro, Steven D.;
Dolganov, Gregory;
Glick, Adam;
Sheppard, Dean

Publication type:

Article

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.

Published in:

Nature Immunology, 2014, v. 15, n. 12, p. 1162, doi. 10.1038/ni.3026

By:

Simpson, Laura J;
Patel, Sana;
Bhakta, Nirav R;
Choy, David F;
Brightbill, Hans D;
Ren, Xin;
Wang, Yanli;
Pua, Heather H;
Baumjohann, Dirk;
Montoya, Misty M;
Panduro, Marisella;
Remedios, Kelly A;
Huang, Xiaozhu;
Fahy, John V;
Arron, Joseph R;
Woodruff, Prescott G;
Ansel, K Mark

Publication type:

Article

Oxidation increases mucin polymer cross-links to stiffen airway mucus gels.

Published in:

Science Translational Medicine, 2015, v. 7, n. 276, p. 1, doi. 10.1126/scitranslmed.3010525

By:

Shaopeng Yuan;
Hollinger, Martin;
Lachowicz-Scroggins, Marrah E.;
Kerr, Sheena C.;
Dunican, Eleanor M.;
Daniel, Brian M.;
Ghosh, Sudakshina;
Erzurum, Serpel C.;
Willard, Belinda;
Hazen, Stanley L.;
Xiaozhu Huang;
Carrington, Stephen D.;
Oscarson, Stefan;
Fahy, John V.

Publication type:

Article

Loss of integrin αvβ8 on dendritic cells causes autoimmunity and colitis in mice.

Published in:

Nature, 2007, v. 449, n. 7160, p. 361, doi. 10.1038/nature06110

By:

Travis, Mark A.;
Reizis, Boris;
Melton, Andrew C.;
Masteller, Emma;
Tang, Qizhi;
Proctor, John M.;
Wang, Yanli;
Bernstein, Xin;
Huang, Xiaozhu;
Reichardt, Louis F.;
Bluestone, Jeffrey A.;
Sheppard, Dean

Publication type:

Article

Src-mediated coupling of focal adhesion kinase to integrin αvΒ5 in vascular endothelial growth factor signaling.

Published in:

Journal of Cell Biology, 2002, v. 157, n. 1, p. 149, doi. 10.1083/jcb.200109079

By:

Eliceiri, Brian P.;
Puente, Xose S.;
Hood, John D.;
Stupack, Dwayne G.;
Schlaepfer, David D.;
Huang, Xiaozhu Z.;
Sheppard, Dean;
Cheresh, David A.

Publication type:

Article

Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1.

Published in:

Science Immunology, 2021, v. 6, n. 64, p. 1, doi. 10.1126/sciimmunol.abh0707

By:

Castellanos, Carlos A.;
Ren, Xin;
Gonzalez, Steven Lomeli;
Li, Hong Kun;
Schroeder, Andrew W.;
Liang, Hong-Erh;
Laidlaw, Brian J.;
Hu, Donglei;
Mak, Angel C.Y.;
Eng, Celeste;
Rodríguez-Santana, José R.;
LeNoir, Michael;
Yan, Qi;
Celedón, Juan C.;
Burchard, Esteban G.;
Zamvil, Scott S.;
Ishido, Satoshi;
Locksley, Richard M.;
Cyster, Jason G.;
Huang, Xiaozhu

Publication type:

Article

Works by Huang, Xiaozhu

Integrin α2β1 regulates collagen I tethering to modulate hyperresponsiveness in reactive airway disease models.

Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma.

IL-17A produced by ?? T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction.

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma.

Enhanced pathological angiogenesis in mice lacking β<sub>3</sub> integrin or β<sub>3</sub> and β<sub>5</sub> integrins.

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation.

Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.

The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.

Integrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing.

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

Characterization of integrin β6 and thrombospondin-1 double-null mice.

Mice Lacking the Integrin β5 Subunit Have Accelerated Osteoclast Maturation and Increased Activity in the Estrogen-Deficient State.

Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2.

ADAM33 Is Not Essential for Growth and Development and Does Not Modulate Allergic Asthma in Mice.

IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction.

Sol-Gel Synthesis and Sensing Study of Perovskite CaCu 3 Ti 4 O 12 Nanopowders.

Role of Organic Cation Transporter 1, OCT1 in the Pharmacokinetics and Toxicity of cis-Diammine(pyridine)chloroplatinum(II) and Oxaliplatin in Mice.

AGR2 Is Induced in Asthma and Promotes Allergen-Induced Mucin Overproduction.

Expression Profiling Identifies Klf15 as a Glucocorticoid Target That Regulates Airway Hyperresponsiveness.

Loss of integrin avB6-mediated TGF-B activation causes Mmp12-dependent emphysema.

A microRNA upregulated in asthma airway T cells promotes T<sub>H</sub>2 cytokine production.

Oxidation increases mucin polymer cross-links to stiffen airway mucus gels.

Loss of integrin α<sub>v</sub>β<sub>8</sub> on dendritic cells causes autoimmunity and colitis in mice.

Src-mediated coupling of focal adhesion kinase to integrin αvΒ5 in vascular endothelial growth factor signaling.

Lymph node–resident dendritic cells drive T<sub>H</sub>2 cell development involving MARCH1.