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A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.
Published in:
Science Translational Medicine, 2022, v. 14, n. 662, p. 1, doi. 10.1126/scitranslmed.abj2381
By:
- Blaskovich, Mark A. T.;
- Hansford, Karl A.;
- Butler, Mark S.;
- Ramu, Soumya;
- Kavanagh, Angela M.;
- Jarrad, Angie M.;
- Prasetyoputri, Anggia;
- Pitt, Miranda E.;
- Huang, Johnny X.;
- Lindahl, Fredrik;
- Ziora, Zyta M.;
- Bradford, Tanya;
- Muldoon, Craig;
- Rajaratnam, Premraj;
- Pelingon, Ruby;
- Edwards, David J.;
- Zhang, Bing;
- Amado, Maite;
- Elliott, Alysha G.;
- Zuegg, Johannes
Publication type:
Article
Drug-drug plasma protein binding interactions of ivacaftor.
Published in:
Journal of Molecular Recognition, 2015, v. 28, n. 6, p. 339, doi. 10.1002/jmr.2447
By:
- Schneider, Elena K.;
- Huang, Johnny X.;
- Carbone, Vincenzo;
- Baker, Mark;
- Azad, Mohammad A. K.;
- Cooper, Matthew A.;
- Li, Jian;
- Velkov, Tony
Publication type:
Article
Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.
Published in:
Journal of Molecular Recognition, 2012, v. 25, n. 12, p. 642, doi. 10.1002/jmr.2221
By:
- Huang, Johnny X.;
- Cooper, Matthew A.;
- Baker, Mark A.;
- Azad, Mohammad A. K.;
- Nation, Roger L.;
- Li, Jian;
- Velkov, Tony
Publication type:
Article
An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16950-x
By:
- Elliott, Alysha G.;
- Huang, Johnny X.;
- Neve, Søren;
- Zuegg, Johannes;
- Edwards, Ingrid A.;
- Cain, Amy K.;
- Boinett, Christine J.;
- Barquist, Lars;
- Lundberg, Carina Vingsbo;
- Steen, Jason;
- Butler, Mark S.;
- Mobli, Mehdi;
- Porter, Kaela M.;
- Blaskovich, Mark A. T.;
- Lociuro, Sergio;
- Strandh, Magnus;
- Cooper, Matthew A.
Publication type:
Article
A new antibiotic with potent activity targets MscL.
Published in:
Journal of Antibiotics, 2015, v. 68, n. 7, p. 453, doi. 10.1038/ja.2015.4
By:
- Iscla, Irene;
- Wray, Robin;
- Blount, Paul;
- Larkins-Ford, Jonah;
- Conery, Annie L;
- Ausubel, Frederick M;
- Ramu, Soumya;
- Kavanagh, Angela;
- Huang, Johnny X;
- Blaskovich, Mark A;
- Cooper, Matthew A;
- Obregon-Henao, Andres;
- Orme, Ian;
- Tjandra, Edwin S;
- Stroeher, Uwe H;
- Brown, Melissa H;
- Macardle, Cindy;
- van Holst, Nick;
- Ling Tong, Chee;
- Slattery, Ashley D
Publication type:
Article
Structure-Function Studies of Polymyxin B Lipononapeptides.
Published in:
Molecules, 2019, v. 24, n. 3, p. 553, doi. 10.3390/molecules24030553
By:
- Gallardo-Godoy, Alejandra;
- Hansford, Karl A.;
- Muldoon, Craig;
- Becker, Bernd;
- Elliott, Alysha G.;
- Huang, Johnny X.;
- Pelingon, Ruby;
- Butler, Mark S.;
- Blaskovich, Mark A. T.;
- Cooper, Matthew A.
Publication type:
Article
Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.
Published in:
Molecules, 2015, v. 20, n. 6, p. 10415, doi. 10.3390/molecules200610415
By:
- Carbone, Vincenzo;
- Schneider, Elena K.;
- Rockman, Steve;
- Baker, Mark;
- Huang, Johnny X.;
- Chi Ong;
- Cooper, Matthew A.;
- Yuriev, Elizabeth;
- Jian Li;
- Velkov, Tony
Publication type:
Article
Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.
Published in:
Innate Immunity, 2014, v. 20, n. 4, p. 350, doi. 10.1177/1753425913493337
By:
- Velkov, Tony;
- Deris, Zakuan Z;
- Huang, Johnny X;
- Azad, Mohammad AK;
- Butler, Mark;
- Sivanesan, Sivashangarie;
- Kaminskas, Lisa M;
- Dong, Yao-Da;
- Boyd, Ben;
- Baker, Mark A;
- Cooper, Matthew A;
- Nation, Roger L;
- Li, Jian
Publication type:
Article
Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.
Published in:
Innate Immunity, 2013, v. 19, n. 3, p. 265, doi. 10.1177/1753425912459092
By:
- Velkov, Tony;
- Soon, Rachel L;
- Chong, Pei L;
- Huang, Johnny X;
- Cooper, Matthew A;
- Azad, Mohammad AK;
- Baker, Mark A;
- Thompson, Philip E;
- Roberts, Kade;
- Nation, Roger L;
- Clements, Abigail;
- Strugnell, Richard A;
- Li, Jian
Publication type:
Article
Comparison of Surface Plasmon Resonance, Resonant Waveguide Grating Biosensing and Enzyme Linked Immunosorbent Assay (ELISA) in the Evaluation of a Dengue Virus Immunoassay.
Published in:
Biosensors (2079-6374), 2013, v. 3, n. 3, p. 297, doi. 10.3390/bios3030297
By:
- Dongmei Hu;
- Fry, Scott R.;
- Huang, Johnny X.;
- Xixia Ding;
- Liwen Qiu;
- Yuxian Pan;
- Yue Chen;
- Jing Jin;
- McElnea, Catriona;
- Buechler, Joe;
- Xiaoyan Che;
- Cooper, Matthew A.
Publication type:
Article
Molecular Characterization of Lipopolysaccharide Binding to Human α-1-Acid Glycoprotein.
Published in:
Journal of Lipids, 2012, p. 1, doi. 10.1155/2012/475153
By:
- Huang, Johnny X.;
- Azad, Mohammad A. K.;
- Yuriev, Elizabeth;
- Baker, Mark A.;
- Nation, Roger L.;
- Li, Jian;
- Cooper, Matthew A.;
- Velkov, Tony
Publication type:
Article
Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02123-w
By:
- Blaskovich, Mark A. T.;
- Hansford, Karl A.;
- Yujing Gong;
- Butler, Mark S.;
- Muldoon, Craig;
- Huang, Johnny X.;
- Ramu, Soumya;
- Mu Cheng;
- Kavanagh, Angela M.;
- Ziora, Zyta;
- Premraj, Rajaratnam;
- Lindahl, Fredrik;
- Bradford, Tanya A.;
- Lee, June C.;
- Pelingon, Ruby;
- Edwards, David J.;
- Amado, Maite;
- Elliott, Alysha G.;
- Phetsang, Wanida;
- Daud, Noor Huda
Publication type:
Article
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Published in:
Nature Communications, 2015, v. 6, n. 7, p. 7719, doi. 10.1038/ncomms8719
By:
- Zuegg, Johannes;
- Muldoon, Craig;
- Adamson, George;
- McKeveney, Declan;
- Le Thanh, Giang;
- Premraj, Rajaratnam;
- Becker, Bernd;
- Cheng, Mu;
- Elliott, Alysha G.;
- Huang, Johnny X.;
- Butler, Mark S.;
- Bajaj, Megha;
- Seifert, Joachim;
- Singh, Latika;
- Galley, Nicola F.;
- Roper, David I.;
- Lloyd, Adrian J.;
- Dowson, Christopher G.;
- Cheng, Ting-Jen;
- Cheng, Wei-Chieh
Publication type:
Article
The Diagnostic Sensitivity of Dengue Rapid Test Assays Is Significantly Enhanced by Using a Combined Antigen and Antibody Testing Approach.
Published in:
PLoS Neglected Tropical Diseases, 2011, v. 5, n. 6, p. 1, doi. 10.1371/journal.pntd.0001199
By:
- Fry, Scott R.;
- Meyer, Michelle;
- Semple, Matthew G.;
- Simmons, Cameron P.;
- Sekaran, Shamala Devi;
- Huang, Johnny X.;
- McElnea, Catriona;
- Huang, Chang-Yi;
- Valks, Andrea;
- Young, Paul R.;
- Cooper, Matthew A.
Publication type:
Article
The Diagnostic Sensitivity of Dengue Rapid Test Assays Is Significantly Enhanced by Using a Combined Antigen and Antibody Testing Approach.
Published in:
PLoS Neglected Tropical Diseases, 2011, v. 5, n. 6, p. 1, doi. 10.1371/journal.pntd.0001199
By:
- Fry, Scott R.;
- Meyer, Michelle;
- Semple, Matthew G.;
- Simmons, Cameron P.;
- Sekaran, Shamala Devi;
- Huang, Johnny X.;
- McElnea, Catriona;
- Huang, Chang-Yi;
- Valks, Andrea;
- Young, Paul R.;
- Cooper, Matthew A.
Publication type:
Article
Synthesis of Multivalent [Lys<sup>8</sup>]-Oxytocin Dendrimers that Inhibit Visceral Nociceptive Responses.
Published in:
Australian Journal of Chemistry, 2017, v. 70, n. 2, p. 162, doi. 10.1071/CH16407
By:
- Jingjing Wan;
- Mobli, Mehdi;
- Brust, Andreas;
- Muttenthaler, Markus;
- Andersson, Åsa;
- Ragnarsson, Lotten;
- Castro, Joel;
- Vetter, Irina;
- Huang, Johnny X.;
- Nilsson, Mathias;
- Brierley, Stuart M.;
- Cooper, Matthew A.;
- Lewis, Richard J.;
- Alewood, Paul F.
Publication type:
Article
Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring.
Published in:
G3: Genes | Genomes | Genetics, 2019, v. 9, n. 11, p. 3645, doi. 10.1534/g3.119.400503
By:
- Yan Dong;
- Haimei Li;
- Liang Zhao;
- Koopman, Peter;
- Feng Zhang;
- Huang, Johnny X.
Publication type:
Article
Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells.
Published in:
Pharmacology Research & Perspectives, 2015, v. 3, n. 3, p. 1, doi. 10.1002/prp2.148
By:
- Huang, Johnny X.;
- Kaeslin, Geraldine;
- Ranall, Max V.;
- Blaskovich, Mark A.;
- Becker, Bernd;
- Butler, Mark S.;
- Little, Melissa H.;
- Lash, Lawrence H.;
- Cooper, Matthew A.
Publication type:
Article

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