Works matching AU Huang, Danny T

Results: 16

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 982, doi. 10.1038/nsmb.2621

By:

Dou, Hao;
Buetow, Lori;
Sibbet, Gary J;
Cameron, Kenneth;
Huang, Danny T

Publication type:

Article

BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 876, doi. 10.1038/nsmb.2379

By:

Dou, Hao;
Buetow, Lori;
Sibbet, Gary J;
Cameron, Kenneth;
Huang, Danny T

Publication type:

Article

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 184, doi. 10.1038/nsmb.2231

By:

Dou, Hao;
Buetow, Lori;
Hock, Andreas;
Sibbet, Gary J;
Vousden, Karen H;
Huang, Danny T

Publication type:

Article

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 3, p. 280, doi. 10.1038/nsmb.1387

By:

Huang, Danny T.;
Min Zhuang;
Ayrault, Olivier;
Schulman, Brenda A.

Publication type:

Article

Breaking up with a kinky SUMO.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 12, p. 1045, doi. 10.1038/nsmb1206-1045

By:

Huang, Danny T.;
Schulman, Brenda A.

Publication type:

Article

Crystal Structure of UBA2<sup>ufd</sup>-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015805

By:

Jing Wang;
Taherbhoy, Asad M.;
Hunt, Harold W.;
Seyedin, Steven N.;
Miller, David W.;
Miller, Darcie J.;
Huang, Danny T.;
Schulman, Brenda A.

Publication type:

Article

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response.

Published in:

EMBO Journal, 2024, v. 43, n. 6, p. 904, doi. 10.1038/s44318-024-00044-1

By:

Vringer, Esmee;
Heilig, Rosalie;
Riley, Joel S;
Black, Annabel;
Cloix, Catherine;
Skalka, George;
Montes-Gómez, Alfredo E;
Aguado, Aurore;
Lilla, Sergio;
Walczak, Henning;
Gyrd-Hansen, Mads;
Murphy, Daniel J;
Huang, Danny T;
Zanivan, Sara;
Tait, Stephen WG

Publication type:

Article

PTEN deficiency exposes a requirement for an ARF GTPase module for integrin‐dependent invasion in ovarian cancer.

Published in:

EMBO Journal, 2023, v. 42, n. 18, p. 1, doi. 10.15252/embj.2023113987

By:

Nikolatou, Konstantina;
Sandilands, Emma;
Román‐Fernández, Alvaro;
Cumming, Erin M;
Freckmann, Eva;
Lilla, Sergio;
Buetow, Lori;
McGarry, Lynn;
Neilson, Matthew;
Shaw, Robin;
Strachan, David;
Miller, Crispin;
Huang, Danny T;
McNeish, Iain A;
Norman, James C;
Zanivan, Sara;
Bryant, David M

Publication type:

Article

E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 10, p. 933, doi. 10.1038/nsmb984

By:

Eletr, Ziad M;
Huang, Danny T;
Duda, David M;
Schulman, Brenda A;
Kuhlman, Brian

Publication type:

Article

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 10, p. 927, doi. 10.1038/nsmb826

By:

Huang, Danny T;
Miller, David W;
Mathew, Rose;
Cassell, Robert;
Holton, James M;
Roussel, Martine F;
Schulman, Brenda A

Publication type:

Article

Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function.

Published in:

Life Science Alliance, 2022, v. 5, n. 12, p. 1, doi. 10.26508/lsa.202201472

By:

Kowalczyk, Dominika;
Nakasone, Mark A.;
Smith, Brian O.;
Huang, Danny T.

Publication type:

Article

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15783-y

By:

Magnussen, Helge M.;
Ahmed, Syed F.;
Sibbet, Gary. J.;
Hristova, Ventzislava A.;
Nomura, Koji;
Hock, Andreas K.;
Archibald, Lewis J.;
Jamieson, Andrew G.;
Fushman, David;
Vousden, Karen H.;
Weissman, Allan M.;
Huang, Danny T.

Publication type:

Article

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.

Published in:

BMC Biology, 2016, v. 14, p. 1, doi. 10.1186/s12915-016-0298-6

By:

Buetow, Lori;
Tria, Giancarlo;
Ahmed, Syed Feroj;
Hock, Andreas;
Hao Dou;
Sibbet, Gary J.;
Svergun, Dmitri I.;
Huang, Danny T.

Publication type:

Article

Ubiquitin-like protein activation.

Published in:

Oncogene, 2004, v. 23, n. 11, p. 1958, doi. 10.1038/sj.onc.1207393

By:

Huang, Danny T.;
Walden, Helen;
Duda, David;
Schulman, Brenda A.

Publication type:

Article

Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity.

Published in:

Nature, 2007, v. 445, n. 7126, p. 394, doi. 10.1038/nature05490

By:

Huang, Danny T.;
Hunt, Harold W.;
Zhuang, Min;
Ohi, Melanie D.;
Holton, James M.;
Schulman, Brenda A.

Publication type:

Article

Insights into non-proteinaceous ubiquitination.

Published in:

Biochemical Society Transactions, 2025, v. 53, n. 2, p. 399, doi. 10.1042/BST20253029

By:

Dearlove, Emily L.;
Huang, Danny T.

Publication type:

Article