Found: 28
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Enhanced IGF‐IIRα Expression Exacerbates Lipopolysaccharide‐Induced Cardiac Inflammation, Hypertrophy, and Apoptosis Through Calcineurin Activation.
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- Environmental Toxicology, 2024, v. 39, n. 11, p. 5173, doi. 10.1002/tox.24385
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- Article
Rhodiola and Salidroside Attenuate Oxidative Stress‐Triggered H9c2 Cardiomyoblast Apoptosis Through IGF1R‐Induced ERK1/2 Activation.
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- Environmental Toxicology, 2024, v. 39, n. 11, p. 5150, doi. 10.1002/tox.24372
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- Article
Low‐concentration imiquimod treatment promotes enhanced skin barrier functions through epidermal melanization reaction regulation.
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- Environmental Toxicology, 2024, v. 39, n. 9, p. 4360, doi. 10.1002/tox.24332
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- Article
Ohwia caudata extract relieves the IL‐17A‐induced inflammatory response of synoviocytes through modulation of SOCS3 and JAK2/STAT3 activation.
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- Environmental Toxicology, 2023, v. 38, n. 8, p. 1914, doi. 10.1002/tox.23818
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- Article
Garcinol protects SH‐SY5Y cells against MPP+‐induced cell death by activating DJ‐1/SIRT1 and PGC‐1α mediated antioxidant pathway in sequential stimulation of p‐AMPK mediated autophagy.
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- Environmental Toxicology, 2023, v. 38, n. 4, p. 857, doi. 10.1002/tox.23737
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- Article
Insulin‐like growth factor II receptor alpha overexpression in heart aggravates hyperglycemia‐induced cardiac inflammation and myocardial necrosis.
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- Environmental Toxicology, 2023, v. 38, n. 3, p. 676, doi. 10.1002/tox.23717
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- Article
Overexpression of cardiac‐specific IGF‐IIRα accelerates the development of liver dysfunction through STZ‐induced diabetic hepatocyte damage in transgenic rats.
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- Environmental Toxicology, 2022, v. 37, n. 11, p. 2804, doi. 10.1002/tox.23638
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- Article
Isoliquiritigenin ameliorates advanced glycation end‐products toxicity on renal proximal tubular epithelial cells.
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- Environmental Toxicology, 2022, v. 37, n. 8, p. 2096, doi. 10.1002/tox.23553
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- Article
Tanshinone IIA inhibits Leu27IGF‐II‐induced insulin‐like growth factor receptor II signaling and myocardial apoptosis via estrogen receptor‐mediated Akt activation.
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- Environmental Toxicology, 2022, v. 37, n. 1, p. 142, doi. 10.1002/tox.23385
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- Article
Cardioprotective effects of transplanted adipose‐derived stem cells under Ang II stress with Danggui administration augments cardiac function through upregulation of insulin‐like growth factor 1 receptor in late‐stage hypertension rats.
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- Environmental Toxicology, 2021, v. 36, n. 7, p. 1466, doi. 10.1002/tox.23145
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- Article
Poria cocos (Fuling) targets TGFβ/Smad7 associated collagen accumulation and enhances Nrf2‐antioxidant mechanism to exert anti‐skin aging effects in human dermal fibroblasts.
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- Environmental Toxicology, 2021, v. 36, n. 5, p. 729, doi. 10.1002/tox.23075
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- Article
Bioactive peptides attenuate cardiac apoptosis in spontaneously hypertensive rat hearts through activation of autophagy and mitochondrial biogenesis pathway.
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- Environmental Toxicology, 2020, v. 35, n. 7, p. 804, doi. 10.1002/tox.22916
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- Article
Deep sea minerals ameliorate diabetic‐induced inflammation via inhibition of TNFα signaling pathways.
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- Environmental Toxicology, 2020, v. 35, n. 4, p. 468, doi. 10.1002/tox.22882
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- Article
LPS‐enhanced IGF‐IIR pathway to induce H9c2 cardiomyoblast cell hypertrophy was attenuated by Carthamus tinctorius extract via IGF‐IR activation.
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- Environmental Toxicology, 2020, v. 35, n. 2, p. 145, doi. 10.1002/tox.22850
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- Article
Mitotic arrest induced in human DU145 prostate cancer cells in response to KHC-4 treatment.
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- Environmental Toxicology, 2016, v. 31, n. 12, p. 1879, doi. 10.1002/tox.22189
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- Article
Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2608, doi. 10.3390/ijms21072608
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- Article
17β-Estradiol and/or Estrogen Receptor β Attenuate the Autophagic and Apoptotic Effects Induced by Prolonged Hypoxia Through HIF-1α-Mediated BNIP3 and IGFBP-3 Signaling Blockage.
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- Cellular Physiology & Biochemistry (Karger AG), 2015, v. 36, n. 1, p. 274, doi. 10.1159/000374070
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- Article
Tannic Acid Impedes the Proliferation of Bladder Cancer Cells by Elevating Mitochondrial Pathways of Apoptosis.
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- Cell Biochemistry & Biophysics, 2024, v. 82, n. 2, p. 1325, doi. 10.1007/s12013-024-01286-w
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- Article
ZAKβ Alleviates Oxidized Low-density Lipoprotein (ox-LDL)-Induced Apoptosis and B-type Natriuretic Peptide (BNP) Upregulation in Cardiomyoblast.
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- Cell Biochemistry & Biophysics, 2022, v. 80, n. 3, p. 547, doi. 10.1007/s12013-022-01080-6
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- Article
Diosgenin Attenuates Myocardial Cell Apoptosis Triggered by Oxidative Stress through Estrogen Receptor to Activate the PI3K/Akt and ERK Axes.
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- American Journal of Chinese Medicine, 2023, v. 51, n. 5, p. 1211, doi. 10.1142/S0192415X23500556
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- Article
Curcumin-Pretreated Adipose-Derived Stem Cells Enhance the Neuroprotective Ability to Repair Rheumatoid Arthritis-Induced Damage in the Rat Brain.
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- American Journal of Chinese Medicine, 2022, v. 50, n. 5, p. 1299, doi. 10.1142/S0192415X22500549
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- Article
Tanshinone IIA Prevents Leu27IGF-II-Induced Cardiomyocyte Hypertrophy Mediated by Estrogen Receptor and Subsequent Akt Activation.
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- American Journal of Chinese Medicine, 2015, v. 43, n. 8, p. 1567, doi. 10.1142/S0192415X15500895
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- Article
Hyperphosphate-Induced Myocardial Hypertrophy through the GATA-4/NFAT-3 Signaling Pathway Is Attenuated by ERK Inhibitor Treatment.
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- CardioRenal Medicine, 2015, v. 5, n. 2, p. 79, doi. 10.1159/000371454
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Protective effects of electroacupuncture at LR3 on cardiac hypertrophy and apoptosis in hypertensive rats.
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- Acupuncture in Medicine, 2016, v. 34, n. 3, p. 201, doi. 10.1136/acupmed-2015-010782
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Ohwia caudata inhibits doxorubicin‐induced cardiotoxicity by regulating mitochondrial dynamics via the IGF‐IIR/p‐Drp1/PARP signaling pathway.
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- Biotechnology & Applied Biochemistry, 2024, v. 71, n. 5, p. 1181, doi. 10.1002/bab.2620
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- Article
Cardiac-specific overexpression of insulin-like growth factor II receptor-α interferes with the regulation of calcium homeostasis in the heart under hyperglycemic conditions.
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- Molecular Biology Reports, 2023, v. 50, n. 5, p. 4329, doi. 10.1007/s11033-023-08327-2
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P38 mitogen-activated protein kinase pathways are involved in the hypertrophy and apoptosis of cardiomyocytes induced by Porphyromonas gingivalis conditioned medium.
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- Cell Biochemistry & Function, 2008, v. 26, n. 2, p. 246, doi. 10.1002/cbf.1443
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Impaired IGF-I signalling of hypertrophic hearts in the developmental phase of hypertension in genetically hypertensive rats.
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- Cell Biochemistry & Function, 2005, v. 23, n. 5, p. 325, doi. 10.1002/cbf.1244
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- Article