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Characterization of Mice Carrying a Neurodevelopmental Disease-Associated GluN2B(L825V) Variant.
Published in:
Journal of Neuroscience, 2024, v. 44, n. 31, p. 1, doi. 10.1523/JNEUROSCI.2291-23.2024
By:
- Serra, Miriam Candelas;
- Kuchtiak, Viktor;
- Kubik-Zahorodna, Agnieszka;
- Kysilov, Bohdan;
- Fili, Klevinda;
- Krausova, Barbora Hrcka;
- Abramova, Vera;
- Dobrovolski, Mark;
- Harant, Karel;
- Bozikova, Paulina;
- Cerny, Jiri;
- Prochazka, Jan;
- Kasparek, Petr;
- Sedlacek, Radislav;
- Balik, Ales;
- Smejkalova, Tereza;
- Vyklicky, Ladislav
Publication type:
Article
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
Published in:
Journal of Neuroscience, 2023, v. 43, n. 26, p. 4755, doi. 10.1523/JNEUROSCI.2014-22.2023
By:
- Kortus, Stepan;
- Rehakova, Kristyna;
- Klima, Martin;
- Kolcheva, Marharyta;
- Ladislav, Marek;
- Langore, Emily;
- Barackova, Petra;
- Netolicky, Jakub;
- Misiachna, Anna;
- Hemelikova, Katarina;
- Humpolickova, Jana;
- Chalupska, Dominika;
- Silhan, Jan;
- Kaniakova, Martina;
- Krausova, Barbora Hrcka;
- Boura, Evzen;
- Zapotocky, Martin;
- Horak, Martin
Publication type:
Article
Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia.
Published in:
Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 1026, doi. 10.3390/biom11071026
By:
- Holubova, Kristina;
- Chvojkova, Marketa;
- Hrcka Krausova, Barbora;
- Vyklicky, Vojtech;
- Kudova, Eva;
- Chodounska, Hana;
- Vyklicky, Ladislav;
- Vales, Karel
Publication type:
Article
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.
Published in:
Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-023-05062-6
By:
- Kysilov, Bohdan;
- Kuchtiak, Viktor;
- Hrcka Krausova, Barbora;
- Balik, Ales;
- Korinek, Miloslav;
- Fili, Klevinda;
- Dobrovolski, Mark;
- Abramova, Vera;
- Chodounska, Hana;
- Kudova, Eva;
- Bozikova, Paulina;
- Cerny, Jiri;
- Smejkalova, Tereza;
- Vyklicky, Ladislav
Publication type:
Article
The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75646-w
By:
- Skrenkova, Kristyna;
- Song, Jae-man;
- Kortus, Stepan;
- Kolcheva, Marharyta;
- Netolicky, Jakub;
- Hemelikova, Katarina;
- Kaniakova, Martina;
- Krausova, Barbora Hrcka;
- Kucera, Tomas;
- Korabecny, Jan;
- Suh, Young Ho;
- Horak, Martin
Publication type:
Article
Pregnane‐based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss‐of‐function disease‐associated GRIN mutations.
Published in:
British Journal of Pharmacology, 2022, v. 179, n. 15, p. 3970, doi. 10.1111/bph.15841
By:
- Kysilov, Bohdan;
- Hrcka Krausova, Barbora;
- Vyklicky, Vojtech;
- Smejkalova, Tereza;
- Korinek, Miloslav;
- Horak, Martin;
- Chodounska, Hana;
- Kudova, Eva;
- Cerny, Jiri;
- Vyklicky, Ladislav
Publication type:
Article
Pharmacokinetic, pharmacodynamic, and behavioural studies of deschloroketamine in Wistar rats.
Published in:
British Journal of Pharmacology, 2022, v. 179, n. 1, p. 65, doi. 10.1111/bph.15680
By:
- Štefková‐Mazochová, Kristýna;
- Danda, Hynek;
- Dehaen, Wim;
- Jurásek, Bronislav;
- Šíchová, Klára;
- Pinterová‐Leca, Nikola;
- Mazoch, Vladimír;
- Krausová, Barbora Hrčka;
- Kysilov, Bohdan;
- Smejkalová, Tereza;
- Vyklický, Ladislav;
- Kohout, Michal;
- Hájková, Kateřina;
- Svozil, Daniel;
- Horsley, Rachel R.;
- Kuchař, Martin;
- Páleníček, Tomáš
Publication type:
Article
Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms.
Published in:
British Journal of Pharmacology, 2021, v. 178, n. 19, p. 3888, doi. 10.1111/bph.15529
By:
- Smejkalova, Tereza;
- Korinek, Miloslav;
- Krusek, Jan;
- Hrcka Krausova, Barbora;
- Candelas Serra, Miriam;
- Hajdukovic, Dragana;
- Kudova, Eva;
- Chodounska, Hana;
- Vyklicky, Ladislav
Publication type:
Article
Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity.
Published in:
Journal of Neuroscience, 2021, v. 41, n. 10, p. 2134, doi. 10.1523/JNEUROSCI.2654-20.2021
By:
- Hubalkova, Pavla;
- Ladislav, Marek;
- Vyklicky, Vojtech;
- Smejkalova, Tereza;
- Krausova, Barbora Hrcka;
- Kysilov, Bohdan;
- Krusek, Jan;
- Naimová, Zaneta;
- Korinek, Miloslav;
- Chodounska, Hana;
- Kudova, Eva;
- Cerny, Jiri;
- Vyklicky Jr, Ladislav
Publication type:
Article
Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor.
Published in:
Journal of Neuroscience, 2020, v. 40, n. 31, p. 5922, doi. 10.1523/jneurosci.3010-19.2020
By:
- Krausova, Barbora Hrcka;
- Kysilov, Bohdan;
- Cerny, Jiri;
- Vyklicky, Vojtech;
- Smejkalova, Tereza;
- Ladislav, Marek;
- Balik, Ales;
- Korinek, Miloslav;
- Chodounska, Hana;
- Kudova, Eva;
- Vyklicky, Ladislav
Publication type:
Article
Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology.
Published in:
Physiological Research, 2024, v. 73, p. S413, doi. 10.33549/physiolres.935346
By:
- KORINEK, Miloslav;
- SERRA, Miriam CANDELAS;
- ABDEL RAHMAN, Fatma Elzahraa S.;
- DOBROVOLSKI, Mark;
- KUCHTIAK, Viktor;
- ABRAMOVA, Vera;
- FILI, Klevinda;
- TOMOVIC, Eni;
- KRAUSOVA, Barbora HRCKA;
- KRUSEK, Jan;
- CERNY, Jiri;
- VYKLICKY, Ladislav;
- BALIK, Ales;
- SMEJKALOVA, Tereza
Publication type:
Article

Found: 11