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A-series agent A-234: initial in vitro and in vivo characterization.
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- Archives of Toxicology, 2024, v. 98, n. 4, p. 1135, doi. 10.1007/s00204-024-03689-3
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- Article
A-agents, misleadingly known as "Novichoks": a narrative review.
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- Archives of Toxicology, 2023, v. 97, n. 10, p. 2587, doi. 10.1007/s00204-023-03571-8
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- Article
Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity.
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- Archives of Toxicology, 2023, v. 97, n. 8, p. 2209, doi. 10.1007/s00204-023-03525-0
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- Article
Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9124, doi. 10.3390/ijms24119124
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- Article
PHENOTHIAZINE-TACRINE HETERODIMERS: PURSUING MULTITARGET DIRECTED APPROACH IN ALZHEIMER'S DISEASE.
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- 2022
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- Abstract
NOVICHOK: BASIC KNOWLEDGE OF BIOCHEMICAL PROPERTIES.
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- 2022
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- Abstract
2-PROPARGAYLAMINO-NAPHTHOQUINONE DERIVATIVES AS MULTIPOTENT AGENTS FOR THE TREATMENT OFALZHEIMER'S DISEASE.
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- 2022
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- Abstract
Heterocyclic Cathinones as Inhibitors of Kynurenine Aminotransferase II—Design, Synthesis, and Evaluation.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 12, p. 1291, doi. 10.3390/ph14121291
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- Article
Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8308, doi. 10.3390/ijms22158308
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- Article
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.
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- Archives of Toxicology, 2021, v. 95, n. 3, p. 985, doi. 10.1007/s00204-021-02981-w
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- Article
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N -Methyl-d-Aspartate Receptor Antagonists.
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- Biomolecules (2218-273X), 2021, v. 11, n. 1, p. 3, doi. 10.3390/biom11010003
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- Article
Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats.
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- Iranian Journal of Pharmaceutical Research, 2020, v. 19, n. 3, p. 95, doi. 10.22037/ijpr.2019.1100723
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- Article
Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase.
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- Biomolecules (2218-273X), 2020, v. 10, n. 5, p. 800, doi. 10.3390/biom10050800
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- Article
Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 2059, doi. 10.3390/ijms21062059
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- Article
Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors.
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- Biomolecules (2218-273X), 2019, v. 9, n. 8, p. 379, doi. 10.3390/biom9080379
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- Article
Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease.
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- Molecules, 2019, v. 24, n. 7, p. 1307, doi. 10.3390/molecules24071307
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- Article
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier.
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- Molecules, 2019, v. 24, n. 7, p. 1340, doi. 10.3390/molecules24071340
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- Article
OXIMES WITH ORTHO-POSITIONED CHLORINE MOIETY EXHIBIT IMPROVED PHYSICAL-CHEMICAL PROPERTIES, EFFICIENT REACTIVATION OF INHIBITED HUMAN ACETYLCHOLINESTERASE AND REDUCED IN VIVO TOXICITY.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 20
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- Article
DISCOVERY AND CHARACTERIZATION OF TACRINE/HUPRINE-TRYPTOPHAN HETERODIMERS AS NOVEL MULTIPOTENT COMPOUNDS AGAINST ALZHEIMER'S DISEASE.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 71
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- Article
7-MEOTA-DONEPEZIL HYBRIDS: POTENTIAL CHOLINESTERASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 128
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- Article
Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon.
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- Molecules, 2018, v. 23, n. 5, p. 1103, doi. 10.3390/molecules23051103
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- Article
Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings.
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- Drug Design, Development & Therapy, 2018, v. 12, p. 505, doi. 10.2147/DDDT.S133038
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- Article
A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase.
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- BMC Pharmacology & Toxicology, 2018, v. 19, p. 1, doi. 10.1186/s40360-018-0196-3
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- Article
Alkaloids from <italic>Narcissus poeticus</italic> cv. Pink Parasol of various structural types and their biological activity.
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- Archives of Pharmacal Research, 2018, v. 41, n. 2, p. 208, doi. 10.1007/s12272-017-1000-4
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- Article
Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
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- Molecules, 2017, v. 22, n. 8, p. 1265, doi. 10.3390/molecules22081265
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- Article
Cholinesterase and Prolyl Oligopeptidase Inhibitory Activities of Alkaloids from Argemone platyceras (Papaveraceae).
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- Molecules, 2017, v. 22, n. 7, p. 1181, doi. 10.3390/molecules22071181
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- Article
Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.
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- Molecules, 2017, v. 22, n. 6, p. 1006, doi. 10.3390/molecules22061006
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- Article
Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
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- ChemMedChem, 2016, v. 11, n. 12, p. 1264, doi. 10.1002/cmdc.201500383
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- Article
Isoquinoline Alkaloids from Fumaria officinalis L. and Their Biological Activities Related to Alzheimer's Disease.
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- Chemistry & Biodiversity, 2016, v. 13, n. 1, p. 91, doi. 10.1002/cbdv.201500033
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- Article
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.
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- Molecules, 2015, v. 20, n. 12, p. 22084, doi. 10.3390/molecules201219836
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- Article
Assessment of Acetylcholinesterase Activity Using Indoxylacetate and Comparison with the Standard Ellman's Method.
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- International Journal of Molecular Sciences, 2011, v. 12, n. 4, p. 2631, doi. 10.3390/ijms12042631
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- Article
Novel Bisquaternary Oximes -- Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon.
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- Molecules, 2009, v. 14, n. 12, p. 4915, doi. 10.3390/molecules14124915
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- Article
Reactivation of Human Brain Homogenate Cholinesterases Inhibited by Tabun using Newly Developed Oximes K117 and K127.
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- Basic & Clinical Pharmacology & Toxicology, 2009, v. 105, n. 3, p. 207, doi. 10.1111/j.1742-7843.2009.00421.x
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- Article
Evaluation of Cholinesterase Activities During in Vivo Intoxication Using an Electrochemical Sensor Strip -Correlation With Intoxication Symptoms.
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- Sensors (14248220), 2009, v. 9, n. 5, p. 3627, doi. 10.3390/s90503627
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- Article
Russian VX: Inhibition and Reactivation of Acetylcholinesterase Compared with VX Agent.
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- Basic & Clinical Pharmacology & Toxicology, 2006, v. 98, n. 4, p. 389, doi. 10.1111/j.1742-7843.2006.pto_267.x
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- Article