Works by Houweling, Peter J.

Results: 23

A phase 2 open-label study of the safety and efficacy of weekly dosing of ATL1102 in patients with non-ambulatory Duchenne muscular dystrophy and pharmacology in mdx mice.

Published in:

PLoS ONE, 2024, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0294847

By:

Woodcock, Ian R.;
Tachas, George;
Desem, Nuket;
Houweling, Peter J.;
Kean, Michael;
Emmanuel, Jaiman;
Kennedy, Rachel;
Carroll, Kate;
de Valle, Katy;
Adams, Justine;
Lamandé, Shireen R.;
Coles, Chantal;
Tiong, Chrystal;
Burton, Matthew;
Villano, Daniella;
Button, Peter;
Hogrel, Jean-Yves;
Catling-Seyffer, Sarah;
Ryan, Monique M.;
Delatycki, Martin B.

Publication type:

Article

An Update on Reported Variants in the Skeletal Muscle α‐Actin (ACTA1) Gene.

Published in:

Human Mutation, 2024, v. 2024, p. 1, doi. 10.1155/2024/6496088

By:

Clayton, Joshua S.;
Johari, Mridul;
Taylor, Rhonda L.;
Dofash, Lein;
Allan, Georgina;
Monahan, Gavin;
Houweling, Peter J.;
Ravenscroft, Gianina;
Laing, Nigel G.;
Aziz, Aziz ur Rehman

Publication type:

Article

A Spotlight on T Lymphocytes in Duchenne Muscular Dystrophy—Not Just a Muscle Defect.

Published in:

Biomedicines, 2022, v. 10, n. 3, p. 535, doi. 10.3390/biomedicines10030535

By:

Coles, Chantal A.;
Woodcock, Ian;
Pellicci, Daniel G.;
Houweling, Peter J.

Publication type:

Article

ACTN3 R577X and ACE I/D gene variants influence performance in elite sprinters: a multi-cohort study.

Published in:

BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2462-3

By:

Papadimitriou, Ioannis D.;
Lucia, Alejandro;
Pitsiladis, Yannis P.;
Pushkarev, Vladimir P.;
Dyatlov, Dmitry A.;
Orekhov, Evgeniy F.;
Artioli, Guilherme G.;
Guilherme, Joäo Paulo L. F.;
Lancha Jr., Antonio H.;
Gineviciene, Valentina;
Cieszczyk, Pawel;
Maciejewska-Karlowska, Agnieszka;
Sawczuk, Marek;
Muniesa, Carlos A.;
Kouvatsi, Anastasia;
Massidda, Myosotis;
Calò, Carla Maria;
Garton, Fleur;
Peter J. Houweling;
Guan Wang

Publication type:

Article

Loss of α-actinin-3 confers protection from eccentric contraction damage in fast-twitch EDL muscles from aged mdx dystrophic mice by reducing pathological fibre branching.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 9, p. 1417, doi. 10.1093/hmg/ddab326

By:

Kiriaev, Leonit;
Houweling, Peter J;
North, Kathryn N;
Head, Stewart I

Publication type:

Article

No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147330

By:

Rankinen, Tuomo;
Fuku, Noriyuki;
Wolfarth, Bernd;
Wang, Guan;
Sarzynski, Mark A.;
Alexeev, Dmitry G.;
Ahmetov, Ildus I.;
Boulay, Marcel R.;
Cieszczyk, Pawel;
Eynon, Nir;
Filipenko, Maxim L.;
Garton, Fleur C.;
Generozov, Edward V.;
Govorun, Vadim M.;
Houweling, Peter J.;
Kawahara, Takashi;
Kostryukova, Elena S.;
Kulemin, Nickolay A.;
Larin, Andrey K.;
Maciejewska-Karłowska, Agnieszka

Publication type:

Article

No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes.

Published in:

BMC Genomics, 2018, v. 19, p. 1, doi. 10.1186/s12864-017-4412-0

By:

Papadimitriou, Ioannis D.;
Lockey, Sarah J.;
Voisin, Sarah;
Herbert, Adam J.;
Garton, Fleur;
Houweling, Peter J.;
Cieszczyk, Pawel;
Maciejewska-Skrendo, Agnieszka;
Sawczuk, Marek;
Massidda, Myosotis;
Calò, Carla Maria;
Astratenkova, Irina V.;
Kouvatsi, Anastasia;
Druzhevskaya, Anastasiya M.;
Jacques, Macsue;
Ahmetov, Ildus I.;
Stebbings, Georgina K.;
Heffernan, Shane;
Day, Stephen H.;
Erskine, Robert

Publication type:

Article

Is evolutionary loss our gain? The role of ACTN3 p.Arg577Ter (R577X) genotype in athletic performance, ageing, and disease.

Published in:

Human Mutation, 2018, v. 39, n. 12, p. 1774, doi. 10.1002/humu.23663

By:

Houweling, Peter J.;
Papadimitriou, Ioannis D.;
Seto, Jane T.;
Pérez, Laura M.;
Coso, Juan Del;
North, Kathryn N.;
Lucia, Alejandro;
Eynon, Nir

Publication type:

Article

Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function.

Published in:

Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.771499

By:

Kiriaev, Leonit;
Kueh, Sindy;
Morley, John W.;
North, Kathryn N.;
Houweling, Peter J.;
Head, Stewart I.

Publication type:

Article

Absence of the Z-disc protein α-actinin-3 impairs the mechanical stability of Actn3KO mouse fast-twitch muscle fibres without altering their contractile properties or twitch kinetics.

Published in:

Skeletal Muscle, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13395-022-00295-8

By:

Haug, Michael;
Reischl, Barbara;
Nübler, Stefanie;
Kiriaev, Leonit;
Mázala, Davi A. G.;
Houweling, Peter J.;
North, Kathryn N.;
Friedrich, Oliver;
Head, Stewart I.

Publication type:

Article

Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 14143, doi. 10.1038/ncomms14143

By:

Hogarth, Marshall W.;
Houweling, Peter J.;
Thomas, Kristen C.;
Gordish-Dressman, Heather;
Bello, Luca;
Pegoraro, Elena;
Hoffman, Eric P.;
Head, Stewart I.;
North, Kathryn N.

Publication type:

Article

Properties of extensor digitorum longus muscle and skinned fibers from adult and aged male and female Actn3 knockout mice.

Published in:

Muscle & Nerve, 2011, v. 43, n. 1, p. 37, doi. 10.1002/mus.21778

By:

Chan, Stephen;
Seto, Jane T.;
Houweling, Peter J.;
Yang, Nan;
North, Kathryn N.;
Head, Stewart I.

Publication type:

Article

Vitamin D Receptor Ablation and Vitamin D Deficiency Result in Reduced Grip Strength, Altered Muscle Fibers, and Increased Myostatin in Mice.

Published in:

2015

By:

Girgis, Christian;
Cha, Kuan;
Houweling, Peter;
Rao, Renuka;
Mokbel, Nancy;
Lin, Mike;
Clifton-Bligh, Roderick;
Gunton, Jenny;
Girgis, Christian M;
Cha, Kuan Minn;
Houweling, Peter J;
Clifton-Bligh, Roderick J;
Gunton, Jenny E

Publication type:

journal article

The antioxidants neopterin/7,8‐dihydroneopterin: Novel biomarker and muscle protectant in Duchenne muscular dystrophy.

Published in:

Experimental Physiology, 2018, v. 103, n. 7, p. 939, doi. 10.1113/EP087093

By:

Houweling, Peter J.

Publication type:

Article

Mice with myocyte deletion of vitamin D receptor have sarcopenia and impaired muscle function.

Published in:

Journal of Cachexia, Sarcopenia & Muscle, 2019, v. 10, n. 6, p. 1228, doi. 10.1002/jcsm.12460

By:

Girgis, Christian M.;
Cha, Kuan Minn;
So, Benjamin;
Tsang, Michael;
Chen, Jennifer;
Houweling, Peter J.;
Schindeler, Aaron;
Stokes, Rebecca;
Swarbrick, Michael M.;
Evesson, Frances J.;
Cooper, Sandra T.;
Gunton, Jenny E.

Publication type:

Article

Analysis of the ACTN3 heterozygous genotype suggests that a-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 5, p. 866, doi. 10.1093/hmg/ddv613

By:

Hogarth, Marshall W.;
Garton, Fleur C.;
Houweling, Peter J.;
Tukiainen, Taru;
Lek, Monkol;
Macarthur, Daniel G.;
Seto, Jane T.;
Quinlan, Kate G. R.;
Nan Yang;
Head, Stewart I.;
North, Kathryn N.

Publication type:

Article

Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 15, p. 2914, doi. 10.1093/hmg/ddr196

By:

Seto, Jane T.;
Lek, Monkol;
Quinlan, Kate G.R.;
Houweling, Peter J.;
Zheng, Xi F.;
Garton, Fleur;
MacArthur, Daniel G.;
Raftery, Joanna M.;
Garvey, Sean M.;
Hauser, Michael A.;
Yang, Nan;
Head, Stewart I.;
North, Kathryn N.

Publication type:

Article

Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3).

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16758-9

By:

Knights, Alexander J.;
Vohralik, Emily J.;
Houweling, Peter J.;
Stout, Elizabeth S.;
Norton, Laura J.;
Alexopoulos, Stephanie J.;
Yik, Jinfen. J.;
Mat Jusoh, Hanapi;
Olzomer, Ellen M.;
Bell-Anderson, Kim S.;
North, Kathryn N.;
Hoehn, Kyle L.;
Crossley, Merlin;
Quinlan, Kate G. R.

Publication type:

Article

Evidence Based Selection of Commonly Used RT-qPCR Reference Genes for the Analysis of Mouse Skeletal Muscle.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088653

By:

Thomas, Kristen C.;
Zheng, Xi Fiona;
Garces Suarez, Francia;
Raftery, Joanna M.;
Quinlan, Kate G. R.;
Yang, Nan;
North, Kathryn N.;
Houweling, Peter J.

Publication type:

Article

Altered Ca<sup>2+</sup> Kinetics Associated with α-Actinin-3 Deficiency May Explain Positive Selection for ACTN3 Null Allele in Human Evolution.

Published in:

PLoS Genetics, 2015, v. 11, n. 1, p. 1, doi. 10.1371/journal.pgen.1004862

By:

Head, Stewart I.;
Chan, Stephen;
Houweling, Peter J.;
Quinlan, Kate G. R.;
Murphy, Robyn;
Wagner, Sören;
Friedrich, Oliver;
North, Kathryn N.

Publication type:

Article

Evaluating modified diets and dietary supplement therapies for reducing muscle lipid accumulation and improving muscle function in neurofibromatosis type 1 (NF1).

Published in:

PLoS ONE, 2020, v. 15, n. 8, p. 1, doi. 10.1371/journal.pone.0237097

By:

Vasiljevski, Emily R.;
Houweling, Peter J.;
Rupasinghe, Thusitha;
Kaur, Tarneet;
Summers, Matthew A.;
Roessner, Ute;
Little, David G.;
Schindeler, Aaron

Publication type:

Article

ACTN3 genotype influences muscle performance through the regulation of calcineurin signaling.

Published in:

2013

By:

Seto, Jane T;
Quinlan, Kate G R;
Lek, Monkol;
Zheng, Xi Fiona;
Garton, Fleur;
Macarthur, Daniel G;
Hogarth, Marshall W;
Houweling, Peter J;
Gregorevic, Paul;
Turner, Nigel;
Cooney, Gregory J;
Yang, Nan;
North, Kathryn N

Publication type:

journal article

ACTN3 genotype influences muscle performance through the regulation of calcineurin signaling.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 10, p. 4255, doi. 10.1172/JCI67691

By:

Seto, Jane T.;
Quinlan, Kate G. R.;
Monkol Lek;
Zheng, Xi Fiona;
Garton, Fleur;
MacArthur, Daniel G.;
Hogarth, Marshall W.;
Houweling, Peter J.;
Gregorevic, Paul;
Turner, Nigel;
Cooney, Gregory J.;
Nan Yang;
North, Kathryn N.

Publication type:

Article