Works by Hough, Tertius

Results: 30

Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.

Published in:

FASEB Journal, 2023, v. 37, n. 11, p. 1, doi. 10.1096/fj.202201918R

By:

Bai, Ying;
Bentley, Liz;
Ma, Chao;
Naveenan, Navaratnam;
Cleak, James;
Wu, Yixing;
Simon, Michelle M.;
Westerberg, Henrik;
Cañas, Ramón Casero;
Horner, Neil;
Pandey, Rajesh;
Paphiti, Keanu;
Schulze, Ulrike;
Mianné, Joffrey;
Hough, Tertius;
Teboul, Lydia;
de Baaij, Jeroen H. F.;
Cox, Roger D.

Publication type:

Article

A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas.

Published in:

Nature Genetics, 2004, v. 36, n. 8, p. 894, doi. 10.1038/ng1398

By:

Williamson, Christine M.;
Ball, Simon T.;
Nottingham, Wade T.;
Skinner, Judith A.;
Plagge, Antonius;
Turner, Martin D.;
Powles, Nicola;
Hough, Tertius;
Papworth, David;
Fraser, William D.;
Maconochie, Mark;
Peters, Jo

Publication type:

Article

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.

Published in:

Nature Genetics, 2000, v. 25, n. 4, p. 440, doi. 10.1038/78140

By:

Nolan, Patrick M.;
Peters, Jo;
Strivens, Mark;
Rogers, Derek;
Hagan, Jim;
Spurr, Nigel;
Gray, Ian C.;
Vizor, Lucie;
Brooker, Debra;
Whitehill, Elaine;
Washbourne, Rebecca;
Hough, Tertius;
Greenaway, Simon;
Hewitt, Mazda;
Liu, Xinhong;
McCormack, Stefan;
Pickford, Karen;
Selley, Rachael;
Wells, Christine

Publication type:

Article

HIF--VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants.

Published in:

PLoS Genetics, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.pgen.1002336

By:

Cheeseman, Michael T.;
Tyrer, Hayley E.;
Williams, Debbie;
Hough, Tertius A.;
Pathak, Paras;
Romero, Maria R.;
Hilton, Helen;
Bali, Sulzhan;
Parker, Andrew;
Vizor, Lucie;
Purnell, Tom;
Vowell, Kate;
Wells, Sara;
Bhutta, Mahmood F.;
Potter, Paul K.;
Brown, Steve D. M.

Publication type:

Article

A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy.

Published in:

PLoS Genetics, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.pgen.1001000

By:

Ashrafian, Houman;
Docherty, Louise;
Leo, Vincenzo;
Towlson, Christopher;
Neilan, Monica;
Steeples, Violetta;
Lygate, Craig A.;
Hough, Tertius;
Townsend, Stuart;
Williams, Debbie;
Wells, Sara;
Norris, Dominic;
Glyn-Jones, Sarah;
Land, John;
Barbaric, Ivana;
Lalanne, Zuzanne;
Denny, Paul;
Szumska, Dorota;
Bhattacharya, Shoumo;
Griffin, Julian L.

Publication type:

Article

Mutation at the Evi1 Locus in Junbo Mice Causes Susceptibility to Otitis Media.

Published in:

PLoS Genetics, 2006, v. 3, n. 4, p. 1556, doi. 10.1371/journal.pgen.0020149

By:

Parkinson, Nicholas;
Hardisty-Hughes, Rachel E.;
Tateossian, Hilda;
Hsun-Tien Tsai;
Brooker, Debra;
Morse, Sue;
Lalane, Zuzanna;
MacKenzie, Francesca;
Fray, Martin;
Glenister, Pete;
Woodward, Anne-Marie;
Polley, Sian;
Barbaric, Ivana;
Dear, Neil;
Hough, Tertius A.;
Hunter, A. Jackie;
Cheeseman, Michael T.;
Brown, Steve D. M.

Publication type:

Article

Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2.

Published in:

2010

By:

Grigorieva, Irina V.;
Mirczuk, Samantha;
Gaynor, Katherine U.;
Nesbit, M. Andrew;
Grigorieva, Elena F.;
Qiaozhi Wei;
Ali, Asif;
Fairclough, Rebecca J.;
Stacey, Joanna M.;
Stechman, Michael J.;
Mihai, Radu;
Kurek, Dorota;
Fraser, William D.;
Hough, Tertius;
Condie, Brian G.;
Manley, Nancy;
Grosveld, Frank;
Thakker, Rajesh V.;
Wei, Qiaozhi

Publication type:

journal article

A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X (NFIX) Gene Has Phenotypic Features of Marshall‐Smith Syndrome.

Published in:

JBMR Plus, 2023, v. 7, n. 6, p. 1, doi. 10.1002/jbm4.10739

By:

Kooblall, Kreepa G.;
Stevenson, Mark;
Stewart, Michelle;
Harris, Lachlan;
Zalucki, Oressia;
Dewhurst, Hannah;
Butterfield, Natalie;
Leng, Houfu;
Hough, Tertius A.;
Ma, Da;
Siow, Bernard;
Potter, Paul;
Cox, Roger D.;
Brown, Stephen D.M.;
Horwood, Nicole;
Wright, Benjamin;
Lockstone, Helen;
Buck, David;
Vincent, Tonia L.;
Hannan, Fadil M.

Publication type:

Article

Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0163214

By:

Elshorbagy, Amany K.;
Jernerén, Fredrik;
Scudamore, Cheryl L.;
McMurray, Fiona;
Cater, Heather;
Hough, Tertius;
Cox, Roger;
Refsum, Helga

Publication type:

Article

Chronically elevated branched chain amino acid levels are pro-arrhythmic.

Published in:

Cardiovascular Research, 2022, v. 118, n. 7, p. 1742, doi. 10.1093/cvr/cvab207

By:

Portero, Vincent;
Nicol, Thomas;
Podliesna, Svitlana;
Marchal, Gerard A;
Baartscheer, Antonius;
Casini, Simona;
Tadros, Rafik;
Treur, Jorien L;
Tanck, Michael W T;
Cox, I Jane;
Probert, Fay;
Hough, Tertius A;
Falcone, Sara;
Beekman, Leander;
Müller-Nurasyid, Martina;
Kastenmüller, Gabi;
Gieger, Christian;
Peters, Annette;
Kääb, Stefan;
Sinner, Moritz F

Publication type:

Article

Novel Mouse Model of Autosomal Semidominant Adult Hypophosphatasia Has a Splice Site Mutation in the Tissue Nonspecific Alkaline Phosphatase Gene Akp2.

Published in:

Journal of Bone & Mineral Research, 2007, v. 22, n. 9, p. 1397, doi. 10.1359/JBMR.070515

By:

Hough, Tertius A.;
Polewski, Monika;
Johnson, Kristen;
Cheeseman, Michael;
Nolan, Patrick M.;
Vizor, Lucie;
Rastan, Sohaila;
Boyde, Alan;
Pritzker, Kenneth;
Hunter, A. Jackie;
Fisher, Elizabeth M.C.;
Terkeltaub, Robert;
Brown, Steve D.M.

Publication type:

Article

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.

Published in:

PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006033

By:

Peiris, Heshan;
Duffield, Michael D.;
Fadista, Joao;
Jessup, Claire F.;
Kashmir, Vinder;
Genders, Amanda J.;
McGee, Sean L.;
Martin, Alyce M.;
Saiedi, Madiha;
Morton, Nicholas;
Carter, Roderick;
Cousin, Michael A.;
Kokotos, Alexandros C.;
Oskolkov, Nikolay;
Volkov, Petr;
Hough, Tertius A.;
Fisher, Elizabeth M. C.;
Tybulewicz, Victor L. J.;
Busciglio, Jorge;
Coskun, Pinar E.

Publication type:

Article

Establishing normal plasma and 24-hour urinary biochemistry ranges in C3H, BALB/c and C57BL/6J mice following acclimatization in metabolic cages.

Published in:

Laboratory Animals, 2010, v. 44, n. 3, p. 218, doi. 10.1258/la.2010.009128

By:

Stechman, Michael J.;
Ahmad, Bushra N.;
Loh, Nellie Y.;
Reed, Anita A. C.;
Stewart, Michelle;
Wells, Sara;
Hough, Tertius;
Bentley, Liz;
Cox, Roger D.;
Brown, Steve D. M.;
Thakker, Rajesh V.

Publication type:

Article

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-01995-2

By:

Rozman, Jan;
Rathkolb, Birgit;
Oestereicher, Manuela A.;
Schütt, Christine;
Ravindranath, Aakash Chavan;
Leuchtenberger, Stefanie;
Sharma, Sapna;
Kistler, Martin;
Willershäuser, Monja;
Brommage, Robert;
Meehan, Terrence F.;
Mason, Jeremy;
Haselimashhadi, Hamed;
Hough, Tertius;
Mallon, Ann-Marie;
Wells, Sara;
Santos, Luis;
Lelliott, Christopher J.;
White, Jacqueline K.;
Sorg, Tania

Publication type:

Article

Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis.

Published in:

Journal of Bone & Mineral Research, 2019, v. 34, n. 7, p. 1324, doi. 10.1002/jbmr.3695

By:

Gorvin, Caroline M;
Loh, Nellie Y;
Stechman, Michael J;
Falcone, Sara;
Hannan, Fadil M;
Ahmad, Bushra N;
Piret, Sian E;
Reed, Anita AC;
Jeyabalan, Jeshmi;
Leo, Paul;
Marshall, Mhairi;
Sethi, Siddharth;
Bass, Paul;
Roberts, Ian;
Sanderson, Jeremy;
Wells, Sara;
Hough, Tertius A;
Bentley, Liz;
Christie, Paul T;
Simon, Michelle M

Publication type:

Article

An N‐Ethyl‐N‐Nitrosourea (ENU)‐Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice.

Published in:

Journal of Bone & Mineral Research, 2019, v. 34, n. 3, p. 497, doi. 10.1002/jbmr.3624

By:

Gorvin, Caroline M;
Ahmad, Bushra N;
Stechman, Michael J;
Loh, Nellie Y;
Hough, Tertius A;
Leo, Paul;
Marshall, Mhairi;
Sethi, Siddharth;
Bentley, Liz;
Piret, Sian E;
Reed, Anita;
Jeyabalan, Jeshmi;
Christie, Paul T;
Wells, Sara;
Simon, Michelle M;
Mallon, Ann‐Marie;
Schulz, Herbert;
Huebner, Norbert;
Brown, Matthew A;
Cox, Roger D

Publication type:

Article

A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation.

Published in:

Journal of Bone & Mineral Research, 2012, v. 27, n. 2, p. 413, doi. 10.1002/jbmr.547

By:

Esapa, Christopher T;
Hough, Tertius A;
Testori, Sarah;
Head, Rosie A;
Crane, Elizabeth A;
Chan, Carol PS;
Evans, Holly;
Bassett, JH Duncan;
Tylzanowski, Przemko;
McNally, Eugene G;
Carr, Andrew J;
Boyde, Alan;
Howell, Peter GT;
Clark, Anne;
Williams, Graham R;
Brown, Matthew A;
Croucher, Peter I;
Nesbit, M Andrew;
Brown, Steve DM;
Cox, Roger D

Publication type:

Article

A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.

Published in:

2004

By:

Toye, Ayo A.;
Moir, Lee;
Hugill, Alison;
Bentley, Liz;
Quarterman, Julie;
Mijat, Vesna;
Hough, Tertius;
Goldsworthy, Michelle;
Haynes, Alison;
Hunter, A. Jacqueline;
Browne, Mick;
Spurr, Nigel;
Cox, Roger D.

Publication type:

journal article

Pharmacological Inhibition of FTO.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0121829

By:

McMurray, Fiona;
Demetriades, Marina;
Aik, WeiShen;
Merkestein, Myrte;
Kramer, Holger;
Andrew, Daniel S.;
Scudamore, Cheryl L.;
Hough, Tertius A.;
Wells, Sara;
Ashcroft, Frances M.;
McDonough, Michael A.;
Schofield, Christopher J.;
Cox, Roger D.

Publication type:

Article

Gene Dosage Effects at the Imprinted <i>Gnas</i> Cluster.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065639

By:

Ball, Simon T.;
Kelly, Michelle L.;
Robson, Joan E.;
Turner, Martin D.;
Harrison, Jackie;
Jones, Lynn;
Napper, Diane;
Beechey, Colin V.;
Hough, Tertius;
Plagge, Antonius;
Cattanach, Bruce M.;
Cox, Roger D.;
Peters, Jo

Publication type:

Article

Autosomal Dominant Hypercalciuria in a Mouse Model Due to a Mutation of the Epithelial Calcium Channel, TRPV5.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0055412

By:

Loh, Nellie Y.;
Bentley, Liz;
Dimke, Henrik;
Verkaart, Sjoerd;
Tammaro, Paolo;
Gorvin, Caroline M.;
Stechman, Michael J.;
Ahmad, Bushra N.;
Hannan, Fadil M.;
Piret, Sian E.;
Evans, Holly;
Bellantuono, Ilaria;
Hough, Tertius A.;
Fraser, William D.;
Hoenderop, Joost G. J.;
Ashcroft, Frances M.;
Brown, Steve D. M.;
Bindels, René J. M.;
Cox, Roger D.;
Thakker, Rajesh V.

Publication type:

Article

A Mouse Model for Osseous Heteroplasia.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051835

By:

Cheeseman, Michael T.;
Vowell, Kate;
Hough, Tertius A.;
Jones, Lynn;
Pathak, Paras;
Tyrer, Hayley E.;
Kelly, Michelle;
Cox, Roger;
Warren, Madhuri V.;
Peters, Jo

Publication type:

Article

A Mouse with an N-Ethyl- N-Nitrosourea (ENU) Induced Trp589Arg Galnt3Mutation Represents a Model for Hyperphosphataemic Familial Tumoural Calcinosis.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043205

By:

Esapa, Christopher T.;
Head, Rosie A.;
Jeyabalan, Jeshmi;
Evans, Holly;
Hough, Tertius A.;
Cheeseman, Michael T.;
McNally, Eugene G.;
Carr, Andrew J.;
Thomas, Gethin P.;
Brown, Matthew A.;
Croucher, Peter I.;
Brown, Steve D. M.;
Cox, Roger D.;
Thakker, Rajesh V.;
Aprikyan, Andranik Andrew

Publication type:

Article

A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.

Published in:

Mammalian Genome, 2006, v. 17, n. 2, p. 129, doi. 10.1007/s00335-005-0112-1

By:

Solberg, Leah C.;
Valdar, William;
Gauguier, Dominique;
Nunez, Graciela;
Taylor, Amy;
Burnett, Stephanie;
Arboledas-Hita, Carmen;
Hernandez-Pliego, Polinka;
Davidson, Stuart;
Burns, Peter;
Bhattacharya, Shoumo;
Hough, Tertius;
Higgs, Douglas;
Klenerman, Paul;
Cookson, William O.;
Zhang, Youming;
Deacon, Robert M.;
Rawlins, J. Nicholas P.;
Mott, Richard;
Flint, Jonathan

Publication type:

Article

Novel phenotypes identified by plasma biochemical screening in the mouse.

Published in:

Mammalian Genome, 2002, v. 13, n. 10, p. 595, doi. 10.1007/s00335-002-2188-1

By:

Hough, Tertius A.;
Nolan, Patrick M.;
Tsipouri, Vicky;
Toye, Ayo A.;
Gray, Ian C.;
Goldsworthy, Michelle;
Moir, Lee;
Cox, Roger D.;
Clements, Sian;
Glenister, Peter H.;
Wood, John;
Selley, Rachael L.;
Strivens, Mark A.;
Vizor, Lucie;
McCormack, Stefan L.;
Peters, Josephine;
Fisher, Elizabeth M.;
Spurr, Nigel;
Rastan, Sohaila;
Martin, Joanne E.

Publication type:

Article

Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.

Published in:

Mammalian Genome, 2000, v. 11, n. 7, p. 500, doi. 10.1007/s003350010096

By:

Nolan, Patrick M.;
Peters, Jo;
Vizor, Lucie;
Strivens, Mark;
Washbourne, Rebecca;
Hough, Tertius;
Wells, Christine;
Glenister, Peter;
Thornton, Claire;
Martin, Jo;
Fisher, Elizabeth;
Rogers, Derek;
Hagan, Jim;
Reavill, Charlie;
Gray, Ian;
Wood, John;
Spurr, Nigel;
Browne, Mick;
Rastan, Sohaila;
Hunter, Jackie

Publication type:

Article

Maternal inheritance of the Gnas cluster mutation Ex1A- T affects size, implicating NESP55 in growth.

Published in:

Mammalian Genome, 2013, v. 24, n. 7/8, p. 276, doi. 10.1007/s00335-013-9462-2

By:

Eaton, Sally;
Hough, Tertius;
Fischer-Colbrie, Reiner;
Peters, Jo

Publication type:

Article

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.

Published in:

Mammalian Genome, 2009, v. 20, n. 3, p. 140, doi. 10.1007/s00335-008-9169-y

By:

Pastorelli, Laura M.;
Wells, Sara;
Fray, Martin;
Smith, Adrian;
Hough, Tertius;
Harfe, Brian D.;
McManus, Michael T.;
Smith, Lee;
Woolf, Adrian S.;
Cheeseman, Michael;
Greenfield, Andy

Publication type:

Article

Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 19, p. 3553, doi. 10.1093/hmg/ddp304

By:

Mackenzie, Francesca E.;
Romero, Rosario;
Williams, Debbie;
Gillingwater, Thomas;
Hilton, Helen;
Dick, Jim;
Riddoch-Contreras, Joanna;
Wong, Frances;
Ireson, Lisa;
Powles-Glover, Nicola;
Riley, Genna;
Underhill, Peter;
Hough, Tertius;
Arkell, Ruth;
Greensmith, Linda;
Ribchester, Richard R.;
Blanco, Gonzalo

Publication type:

Article

Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome.

Published in:

Journal of Pathology, 2014, v. 233, n. 1, p. 18, doi. 10.1002/path.4308

By:

Bull, Katherine R;
Mason, Thomas;
Rimmer, Andrew J;
Crockford, Tanya L;
Silver, Karlee L;
Bouriez‐Jones, Tiphaine;
Hough, Tertius A;
Chaudhry, Shirine;
Roberts, Ian SD;
Goodnow, Christopher C;
Cornall, Richard J

Publication type:

Article