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An importance of carbohydrate ingestion for the expression of the effect of alpha-glucosidase inhibitor in NIDDM.
Published in:
1996
By:
- Hara T;
- Nakamura J;
- Koh N;
- Sakakibara F;
- Takeuchi N;
- Hotta N;
- Hara, T;
- Nakamura, J;
- Koh, N;
- Sakakibara, F;
- Takeuchi, N;
- Hotta, N
Publication type:
journal article
Glucose-induced hyperproliferation of cultured rat aortic smooth muscle cells through polyol pathway hyperactivity.
Published in:
Diabetologia, 2001, v. 44, n. 4, p. 480, doi. 10.1007/s001250051646
By:
- Nakamura, J.;
- Kasuya, Y.;
- Hamada, Y.;
- Nakashima, E.;
- Naruse, K.;
- Yasuda, Y.;
- Kato, K.;
- Hotta, N.
Publication type:
Article
Observation of the Fermi pulsar catalog at TeV energies with the Tibet air shower experiment.
Published in:
Astrophysics & Space Sciences Transactions (ASTRA), 2011, v. 7, n. 2, p. 211, doi. 10.5194/astra-7-211-2011
By:
- Amenomori, M.;
- X. J. Bi;
- Chen, D.;
- S. W. Cui;
- Danzengluobu;
- L. K. Ding;
- X. H. Ding;
- C. Fan;
- C. F. Feng;
- Zhaoyang Feng;
- Z. Y. Feng;
- X. Y. Gao;
- Q. X. Geng;
- Q. B. Gou;
- H. W. Guo;
- H. H. He;
- M. He;
- Hibino, K.;
- Hotta, N.;
- Haibing Hu
Publication type:
Article
Cosmic-ray energy spectrum around the knee observed with the Tibet air-shower experiment.
Published in:
Astrophysics & Space Sciences Transactions (ASTRA), 2011, v. 7, n. 1, p. 15
By:
- Amenomori, M.;
- Bi, X. J.;
- Chen, D.;
- Cui, S. W.;
- Danzengluobu;
- Ding, L. K.;
- Ding, X. H.;
- Fan, C.;
- Feng, C. F.;
- Feng, Zhaoyang;
- Feng, Z. Y.;
- Gao, X. Y.;
- Geng, Q. X.;
- Gou, Q. B.;
- Guo, H. W.;
- He, H. H.;
- He, M.;
- Hibino, K.;
- Hotta, N.;
- Hu, Haibing
Publication type:
Article
Hadronic interaction model dependence in cosmic Gamma-ray flux estimation using an extensive air shower array with a muon detector.
Published in:
Experimental Astronomy, 2023, v. 55, n. 2, p. 325, doi. 10.1007/s10686-022-09883-4
By:
- Okukawa, S.;
- Anzorena, M.;
- Asano, S.;
- Condori, C. A. H.;
- de la Fuente, E.;
- Gomi, A.;
- Hibino, K.;
- Hotta, N.;
- Jimenez-Meza, A.;
- Katayose, Y.;
- Kato, C.;
- Kato, S.;
- Kawashima, T.;
- Kawata, K.;
- Koi, T.;
- Kojima, H.;
- Kurashige, D.;
- Lozoya, J.;
- Mayta, R.;
- Miranda, P.
Publication type:
Article
Detectability of southern gamma-ray sources beyond 100 TeV with ALPAQUITA, the prototype experiment of ALPACA.
Published in:
Experimental Astronomy, 2021, v. 52, n. 1/2, p. 85, doi. 10.1007/s10686-021-09796-8
By:
- Kato, S.;
- Condori, C. A. H.;
- Fuente, E. de la;
- Gomi, A.;
- Hibino, K.;
- Hotta, N.;
- Toledano-Juarez, I.;
- Katayose, Y.;
- Kato, C.;
- Kawata, K.;
- Kihara, W.;
- Ko, Y.;
- Koi, T.;
- Kojima, H.;
- Kurashige, D.;
- Lozoya, J.;
- Orozco-Luna, F.;
- Mayta, R.;
- Miranda, P.;
- Munakata, K.
Publication type:
Article
Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic neuropathy
Published in:
Diabetic Medicine, 2012, v. 29, n. 12, p. 1529, doi. 10.1111/j.1464-5491.2012.03684.x
By:
- Hotta, N.;
- Kawamori, R.;
- Fukuda, M.;
- Shigeta, Y.
Publication type:
Article
Stratified analyses for selecting appropriate target patients with diabetic peripheral neuropathy for long-term treatment with an aldose reductase inhibitor, epalrestat.
Published in:
Diabetic Medicine, 2008, v. 25, n. 7, p. 818, doi. 10.1111/j.1464-5491.2008.02490.x
By:
- Hotta, N.;
- Kawamori, R.;
- Atsumi, Y.;
- Baba, M.;
- Kishikawa, H.;
- Nakamura, J.;
- Oikawa, S.;
- Yamada, N.;
- Yasuda, H.;
- Shigeta, Y.
Publication type:
Article
Characteristic patterns of circadian variation in plasma catecholamine levels, blood pressure and heart rate variability in Type 2 diabetic patients.
Published in:
Diabetic Medicine, 2002, v. 19, n. 5, p. 359, doi. 10.1046/j.1464-5491.2002.00720.x
By:
- Kondo, K;
- Matsubara, T;
- Nakamura, J;
- Hotta, N
Publication type:
Article
Eosinophilic gastroenteritis associated with Epstein-Barr virus infection in a young boy.
Published in:
2001
By:
- Koga, Mayumi;
- Fujiwara, Motoki;
- Hotta, Noriko;
- Matsubara, Tomoyo;
- Suzuki, Eitaro;
- Furukawa, Susumu;
- Koga, M;
- Fujiwara, M;
- Hotta, N;
- Matsubara, T;
- Suzuki, E;
- Furukawa, S
Publication type:
journal article
Basal interstitial water pressure in laboratory debris flows over a rigid bed in an open channel.
Published in:
Natural Hazards & Earth System Sciences, 2012, v. 12, n. 8, p. 2499, doi. 10.5194/nhess-12-2499-2012
By:
- Hotta, N.
Publication type:
Article
Sensitivity of the large muon detector with the Tibet air-shower array to measure the primary proton spectrum between 40 and 630 TeV.
Published in:
Progress of Theoretical & Experimental Physics: PTEP, 2022, v. 2022, n. 9, p. 1, doi. 10.1093/ptep/ptac119
By:
- Kurashige, D;
- Hotta, N;
- Katayose, Y;
- Kawata, K;
- Ohnishi, M;
- Saito, T;
- Sako, T K;
- Shibata, M;
- Takita, M
Publication type:
Article
The effect of cigarette smoking on soluble adhesion molecules in middle-aged patients with Type 2 diabetes mellitus.
Published in:
Diabetic Medicine, 2002, v. 19, n. 1, p. 57, doi. 10.1046/j.1464-5491.2002.00631.x
By:
- Takeuchi, N;
- Kawamura, T;
- Kanai, A;
- Nakamura, N;
- Uno, T;
- Hara, T;
- Sano, T;
- Sakamoto, N;
- Hamada, Y;
- Nakamura, J;
- Hotta, N
Publication type:
Article
Effect of aldose reductase inhibitors on glucose-induced changes in sorbitol and myo-inositol metabolism in human neutrophils.
Published in:
1999
By:
- Suzuki, K;
- Kawamura, T;
- Sakakibara, F;
- Sasaki, H;
- Sano, T;
- Sakamoto, N;
- Hotta, N
Publication type:
Journal Article
Effect of aldose reductase inhibitors on glucose- induced changes in sorbitol and myo-inositol metabolism in human neutrophils.
Published in:
Diabetic Medicine, 1999, v. 16, n. 1, p. 67, doi. 10.1046/j.1464-5491.1999.00022.x
By:
- Suzuki, K.;
- Kawamura, T.;
- Sakakibara, F.;
- Sasaki, H;
- Sano, T.;
- Sakamoto, N.;
- Hotta, N.
Publication type:
Article
Effects of long-term enalapril treatment on persistent microalbuminuria in normotensive type 2 diabetic patients: results of a 4-year, prospective, randomized study.
Published in:
1996
By:
- Sano, T;
- Hotta, N;
- Kawamura, T;
- Matsumae, H;
- Chaya, S;
- Sasaki, H;
- Nakayama, M;
- Hara, T;
- Matsuo, S;
- Sakamoto, N
Publication type:
Journal Article
Effects of Glucose and SNK-860, an Aldose Reductase Inhibitor, on the Polyol Pathway and Chemiluminescence Response of Human Neutrophils in vitro.
Published in:
Diabetic Medicine, 1995, v. 12, n. 5, p. 392, doi. 10.1111/j.1464-5491.1995.tb00501.x
By:
- Kawamura, T.;
- Suzuki, K.;
- Matsumae, H.;
- Sano, T.;
- Sakamoto, N.;
- Hotta, N.
Publication type:
Article
Diabetic Neuropathy: Effects of Intensified Glycaemic Control with Multiple Insulin Injections.
Published in:
Diabetic Medicine, 1993, v. 10, n. S2, p. 91S, doi. 10.1111/j.1464-5491.1993.tb00211.x
By:
- Hotta, N.;
- Kawamori, R.;
- Sano, T.;
- Kakuta, H.;
- Kamada, T.;
- Sakamoto, N.
Publication type:
Article
The Effect of Acarbose on Blood Glucose Profiles of Type 2 Diabetic Patients Receiving Insulin Therapy.
Published in:
Diabetic Medicine, 1993, v. 10, n. 4, p. 355, doi. 10.1111/j.1464-5491.1993.tb00079.x
By:
- Hotta, N.;
- Kakuta, H.;
- Koh, N.;
- Sakakibara, F.;
- Haga, T.;
- Sano, T.;
- Okuyama, M.;
- Sakamoto, N.
Publication type:
Article
Long-term Effect of Acarbose on Glycaemic Control in Non-insulin-dependent Diabetes Mellitus: A Placebo-controlled Double-blind Study.
Published in:
Diabetic Medicine, 1993, v. 10, n. 2, p. 134, doi. 10.1111/j.1464-5491.1993.tb00030.x
By:
- Hotta, N.;
- Kakuta, H.;
- Sano, T.;
- Matsumae, H.;
- Yamada, H.;
- Kitazawa, S.;
- Sakamoto, N.
Publication type:
Article
Diabetic neuropathy: effects of intensified glycaemic control with multiple insulin injections.
Published in:
1993
By:
- Hotta, N;
- Kawamori, R;
- Sano, T;
- Kakuta, H;
- Kamada, T;
- Sakamoto, N
Publication type:
Journal Article
A placebo-controlled double-blind study of epalrestat (ONO-2235) in patients with diabetic neuropathy.
Published in:
1993
By:
- Goto, Y;
- Hotta, N;
- Shigeta, Y;
- Sakamoto, N;
- Kito, S;
- Matsuoka, K;
- Takahashi, A;
- Kikkawa, R;
- Sakuma, A
Publication type:
Journal Article
The role of C5a in the development of thrombotic glomerulonephritis in rats.
Published in:
Clinical & Experimental Immunology, 2001, v. 124, n. 2, p. 323, doi. 10.1046/j.1365-2249.2001.01513.x
By:
- Kondo, C.;
- Mizuno, M.;
- Nishikawa, K.;
- Yuzawa, Y.;
- Hotta, N.;
- Matsuo, S.
Publication type:
Article
Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative aldose reductase inhibitor-diabetes complications trial.
Published in:
2006
By:
- Hotta N;
- Akanuma Y;
- Kawamori R;
- Matsuoka K;
- Oka Y;
- Shichiri M;
- Toyota T;
- Nakashima M;
- Yoshimura I;
- Sakamoto N;
- Shigeta Y
Publication type:
Journal Article
Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study.
Published in:
2001
By:
- Hotta, Nigishi;
- Toyota, Takayoshi;
- Matsuoka, Kempei;
- Shigeta, Yukio;
- Kikkawa, Ryuichi;
- Kaneko, Toshio;
- Takahashi, Akira;
- Sugimura, Kimiya;
- Koike, Yasuo;
- Ishii, Jun;
- Sakamoto, Nobuo;
- Hotta, N;
- Toyota, T;
- Matsuoka, K;
- Shigeta, Y;
- Kikkawa, R;
- Kaneko, T;
- Takahashi, A;
- Sugimura, K;
- Koike, Y
Publication type:
journal article
Aldose reductase inhibition ameliorates pupillary light reflex and F-wave latency in patients with mild diabetic neuropathy.
Published in:
2001
By:
- Nakayama, Mikihiro;
- Nakamura, Jiro;
- Hamada, Yoji;
- Chaya, Sadao;
- Mizubayashi, Ryuichi;
- Yasuda, Yutaka;
- Kamiya, Hideki;
- Koh, Naoki;
- Hotta, Nigishi;
- Nakayama, M;
- Nakamura, J;
- Hamada, Y;
- Chaya, S;
- Mizubayashi, R;
- Yasuda, Y;
- Kamiya, H;
- Koh, N;
- Hotta, N
Publication type:
journal article
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
Published in:
2000
By:
- Hamada, Yoji;
- Nakamura, Jiro;
- Naruse, Keiko;
- Komori, Taku;
- Kato, Koichi;
- Kasuya, Yasuhide;
- Nagai, Ryuji;
- Horiuchi, Seikoh;
- Hotta, Nigishi;
- Hamada, Y;
- Nakamura, J;
- Naruse, K;
- Komori, T;
- Kato, K;
- Kasuya, Y;
- Nagai, R;
- Horiuchi, S;
- Hotta, N
Publication type:
journal article
Influence of interindividual variability of aldose reductase protein content on polyol-pathway metabolites and redox state in erythrocytes in diabetic patients.
Published in:
1998
By:
- Hamada, Yoji;
- Nishimura, Chihiro;
- Koh, Naoki;
- Sakakibara, Fumihiko;
- Nakamura, Jiro;
- Tanimoto, Tsuyoshi;
- Hotta, Nigishi;
- Hamada, Y;
- Nishimura, C;
- Koh, N;
- Sakakibara, F;
- Nakamura, J;
- Tanimoto, T;
- Hotta, N
Publication type:
journal article
Effects of glycemic control on plasma 3-deoxyglucosone levels in NIDDM patients.
Published in:
1997
By:
- Hamada, Yoji;
- Nakamura, Jiro;
- Fujisawa, Hiroki;
- Yago, Hisashi;
- Nakashima, Eitaro;
- Koh, Naoki;
- Hotta, Nigishi;
- Hamada, Y;
- Nakamura, J;
- Fujisawa, H;
- Yago, H;
- Nakashima, E;
- Koh, N;
- Hotta, N
Publication type:
journal article
Effects of long-term enalapril treatment on persistent micro-albuminuria in well-controlled hypertensive and normotensive NIDDM patients.
Published in:
1994
By:
- Sano, Takahisa;
- Kawamura, Takahiko;
- Matsumae, Hiromi;
- Sasaki, Hiromitsu;
- Nakayama, Motohiro;
- Hara, Tomohiro;
- Matsuo, Seiichi;
- Hotta, Nigishi;
- Sakamoto, Nobuo;
- Sano, T;
- Kawamura, T;
- Matsumae, H;
- Sasaki, H;
- Nakayama, M;
- Hara, T;
- Matsuo, S;
- Hotta, N;
- Sakamoto, N
Publication type:
journal article
Intravenous immunoglobulin does not increase Fcγ RIIB expression levels on monocytes in children with immune thrombocytopenia.
Published in:
Clinical & Experimental Immunology, 2014, v. 177, n. 2, p. 554, doi. 10.1111/cei.12384
By:
- Shimomura, M.;
- Hasegawa, S.;
- Seki, Y.;
- Fukano, R.;
- Hotta, N.;
- Ichiyama, T.
Publication type:
Article
Intravenous immunoglobulin does not increase FcγRIIB expression levels on monocytes in children with immune thrombocytopenia.
Published in:
Clinical & Experimental Immunology, 2012, v. 169, n. 1, p. 33, doi. 10.1111/j.1365-2249.2012.04591.x
By:
- Shimomura, M.;
- Hasegawa, S.;
- Seki, Y.;
- Fukano, R.;
- Hotta, N.;
- Ichiyama, T.
Publication type:
Article
Effects of the 5-HT Receptor Antagonist Sarpogrelate in Diabetic Patients with Complications : A Pilot Study.
Published in:
Clinical Drug Investigation, 1999, v. 18, n. 3, p. 199, doi. 10.2165/00044011-199918030-00004
By:
- Hotta, N.;
- Nakamura, J.;
- Sumita, Y.;
- Yasuda, K.;
- Ito, M.;
- Takeuchi, T.;
- Hara, T.;
- Sakamoto, N.
Publication type:
Article
The adaptive responses in several mediators linked with hypertrophy and atrophy of skeletal muscle after lower limb unloading in humans.
Published in:
Acta Physiologica, 2009, v. 197, n. 2, p. 151, doi. 10.1111/j.1748-1716.2009.01995.x
By:
- Sakuma, K.;
- Watanabe, K.;
- Hotta, N.;
- Koike, T.;
- Ishida, K.;
- Katayama, K.;
- Akima, H.
Publication type:
Article
Effects of beraprost sodium and insulin on the electroretinogram, nerve conduction, and nerve blood flow in rats with streptozotocin-induced diabetes.
Published in:
1996
By:
- Hotta, Nigishi;
- Koh, Naoki;
- Sakakibara, Fumihiko;
- Nakamura, Jiro;
- Hamada, Yoji;
- Hara, Tomohiro;
- Mori, Koichi;
- Nakashima, Eitaro;
- Naruse, Keiko;
- Fukasawa, Hideo;
- Kakuta, Hironobu;
- Sakamoto, Nobuo;
- Hotta, N;
- Koh, N;
- Sakakibara, F;
- Nakamura, J;
- Hamada, Y;
- Hara, T;
- Mori, K;
- Nakashima, E
Publication type:
journal article
Effects of high glucose concentrations and epalrestat on sorbitol and myo-inositol metabolism in cultured rabbit aortic smooth muscle cells.
Published in:
1993
By:
- Sakakibara, Fumihiko;
- Hotta, Nigishi;
- Koh, Naoli;
- Sakamoto, Nobuo;
- Sakakibara, F;
- Hotta, N;
- Koh, N;
- Sakamoto, N
Publication type:
journal article
Effect of niceritrol on streptozocin-induced diabetic neuropathy in rats.
Published in:
1992
By:
- Hotta, Nigishi;
- Kakuta, Hironobu;
- Fukasawa, Hideo;
- Koh, Naoki;
- Sakakibara, Fumihiko;
- Komori, Hiraku;
- Sakamoto, Nobuo;
- Hotta, N;
- Kakuta, H;
- Fukasawa, H;
- Koh, N;
- Sakakibara, F;
- Komori, H;
- Sakamoto, N
Publication type:
journal article
An aldose reductase inhibitor, TAT, prevents electroretinographic abnormalities and ADP-induced hyperaggregabiIity in streptozotocin-induced diabetic rats.
Published in:
European Journal of Clinical Investigation, 1995, v. 25, n. 12, p. 948, doi. 10.1111/j.1365-2362.1995.tb01972.x
By:
- HOTTA, N.;
- KOH, N.;
- SAKAKIBARA, F.;
- NAKAMURA, J.;
- HAMADA, Y.;
- HARA, T.;
- TAKEUCHI, N.;
- INUKAI, S.;
- KASAMA, N.;
- FUKASAWA, H.;
- KAKUTA, H.
Publication type:
Article
MBP deposition in eosinophilic gastroenteritis.
Published in:
Allergy, 2000, v. 55, n. 10, p. 985, doi. 10.1034/j.1398-9995.2000.00786.x
By:
- Koga, M.;
- Fujiwara, M.;
- Hotta, N.;
- Matsubara, T.;
- Suzuki, E.;
- Furukawa, S.
Publication type:
Article
Underground water Cherenkov muon detector array with the Tibet air shower array for gamma-ray astronomy in the 100 TeV region.
Published in:
Astrophysics & Space Science, 2007, v. 309, n. 1-4, p. 435, doi. 10.1007/s10509-007-9395-x
By:
- Amenomori, M.;
- Ayabe, S.;
- Bi, X.J.;
- Chen, D.;
- Cui, S.W.;
- Danzengluobu;
- Ding, L.K.;
- Ding, X.H.;
- Feng, C.F.;
- Zhaoyang Feng;
- Feng, Z.Y.;
- Gao, X.Y.;
- Geng, Q.X.;
- Guo, H.W.;
- He, H.H.;
- He, M.;
- Hibino, K.;
- Hotta, N.;
- Hu, Haibing;
- Hu, H.B.
Publication type:
Article
Effect Of Protein Kinase C-β Inhibition On Diabetic Neuropathy In Otsuka Long-Evans Tokushima Fatty Rats.
Published in:
Journal of the Peripheral Nervous System, 2000, v. 5, n. 3, p. 181, doi. 10.1046/j.1529-8027.2000.005003181.x
By:
- Kato, K;
- Nakamura, J;
- Kasuya, Y;
- Kamiya, H;
- Akiyama, N;
- Watanabe, G;
- Kawamura, T;
- Hotta, N.
Publication type:
Article
CD59 protects rat kidney from complement mediated injury in collaboration with crry.
Published in:
2000
By:
- Watanabe, Midoriko;
- Morita, Yoshiki;
- Mizuno, Masashi;
- Nishikawa, Kazuhiro;
- Yuzawa, Yukio;
- Hotta, Nigishi;
- Morgan, B. Paul;
- Okada, Noriko;
- Okada, Hidechika;
- Matsuo, Seiichi;
- Watanabe, M;
- Morita, Y;
- Mizuno, M;
- Nishikawa, K;
- Yuzawa, Y;
- Hotta, N;
- Morgan, B P;
- Okada, N;
- Okada, H;
- Matsuo, S
Publication type:
journal article
Magnetic resonance imaging findings in schizophrenia and atypical psychoses.
Published in:
Journal of Neural Transmission, 2001, v. 108, n. 6, p. 695, doi. 10.1007/s007020170046
By:
- Hayashi, T.;
- Hotta, N.;
- Andoh, T.;
- Mori, M.;
- Fukatsu, N.;
- Suga, H.
Publication type:
Article

Found: 43