Works by Hothersall, Joanne

Results: 17

Resistance to and synthesis of the antibiotic mupirocin.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 4, p. 281, doi. 10.1038/nrmicro2278

By:

Thomas, Christopher M.;
Hothersall, Joanne;
Willis, Christine L.;
Simpson, Thomas J.

Publication type:

Article

Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans‐AT Polyketide Synthase Pathway.

Published in:

ChemBioChem, 2018, v. 19, n. 8, p. 836, doi. 10.1002/cbic.201800036

By:

Mohammad, Hadi H.;
Connolly, Jack A.;
Song, Zhongshu;
Hothersall, Joanne;
Race, Paul R.;
Willis, Christine L.;
Simpson, Thomas J.;
Winn, Peter J.;
Thomas, Christopher M.

Publication type:

Article

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390.

Published in:

Angewandte Chemie, 2011, v. 123, n. 14, p. 3329, doi. 10.1002/ange.201007029

By:

Murphy, Annabel C.;
Fukuda, Daisuke;
Song, Zhongshu;
Hothersall, Joanne;
Cox, Russell J.;
Willis, Christine L.;
Thomas, Christopher M.;
Simpson, Thomas J.

Publication type:

Article

Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 3, p. 1017, doi. 10.1007/s00253-011-3145-2

By:

Hothersall, Joanne;
Murphy, Annabel C.;
Iqbal, Zafar;
Campbell, Genevieve;
Stephens, Elton R.;
Ji'en Wu;
Cooper, Helen;
Atkinson, Steve;
Williams, Paul;
Crosby, John;
Willis, Christine L.;
Cox, Russell J.;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

High quality genome annotation and expression visualisation of a mupirocin-producing bacterium.

Published in:

PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0268072

By:

Haines, Anthony S.;
Kendrew, Steve G.;
Crowhurst, Nicola;
Stephens, Elton R.;
Connolly, Jack;
Hothersall, Joanne;
Miller, Claire E.;
Collis, Andrew J.;
Huckle, Benjamin D.;
Thomas, Christopher M.

Publication type:

Article

Inexpensive protein overexpression driven by the NarL transcription activator protein.

Published in:

Biotechnology & Bioengineering, 2022, v. 119, n. 6, p. 1614, doi. 10.1002/bit.28071

By:

Hothersall, Joanne;
Lai, Sandie;
Zhang, Nan;
Godfrey, Rita E.;
Ruanto, Patcharawarin;
Bischoff, Sarah;
Robinson, Colin;
Overton, Tim W.;
Busby, Stephen J. W.;
Browning, Douglas F.

Publication type:

Article

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 14, p. 3271, doi. 10.1002/anie.201007029

By:

Murphy, Annabel C.;
Fukuda, Daisuke;
Song, Zhongshu;
Hothersall, Joanne;
Cox, Russell J.;
Willis, Christine L.;
Thomas, Christopher M.;
Simpson, Thomas J.

Publication type:

Article

Phosphopantetheinylation and Specificity of Acyl Carrier Proteins in the Mupirocin Biosynthetic Cluster.

Published in:

ChemBioChem, 2010, v. 11, n. 2, p. 248, doi. 10.1002/cbic.200900565

By:

Shields, Jennifer A.;
Rahman, Ayesha S.;
Arthur, Christopher J.;
Crosby, John;
Hothersall, Joanne;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

In vivo Mutational Analysis of the Mupirocin Gene Cluster Reveals Labile Points in the Biosynthetic Pathway: the 'Leaky Hosepipe' Mechanism.

Published in:

ChemBioChem, 2008, v. 9, n. 9, p. 1500, doi. 10.1002/cbic.200800085

By:

Wu, Ji'en;
Hothersall, Joanne;
Mazzetti, Carlo;
O'Connell, Yvonne;
Shields, Jennifer A.;
Rahman, Ayesha S.;
Cox, Russell J.;
Crosby, John;
Simpson, Thomas J.;
Thomas, Christopher M.;
Willis, Christine L.

Publication type:

Article

Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-38038-9

By:

Connolly, Jack A.;
Wilson, Amber;
Macioszek, Malgorzata;
Song, Zhongshu;
Wang, Luoyi;
Mohammad, Hadi H.;
Yadav, Mukul;
di Martino, Maura;
Miller, Claire E.;
Hothersall, Joanne;
Haines, Anthony S.;
Stephens, Elton R.;
Crump, Matthew P.;
Willis, Christine L.;
Simpson, Thomas J.;
Winn, Peter J.;
Thomas, Christopher M.

Publication type:

Article

Rücktitelbild: Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics (Angew. Chem. 14/2017).

Published in:

Angewandte Chemie, 2017, v. 129, n. 14, p. 4126, doi. 10.1002/ange.201702123

By:

Gao, Shu ‐ Shan;
Wang, Luoyi;
Song, Zhongshu;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Cox, Russell J.;
Crump, Matthew P.;
Race, Paul R.;
Thomas, Christopher M.;
Simpson, Thomas J.;
Willis, Christine L.

Publication type:

Article

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Published in:

Angewandte Chemie, 2017, v. 129, n. 14, p. 3988, doi. 10.1002/ange.201611590

By:

Gao, Shu ‐ Shan;
Wang, Luoyi;
Song, Zhongshu;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Cox, Russell J.;
Crump, Matthew P.;
Race, Paul R.;
Thomas, Christopher M.;
Simpson, Thomas J.;
Willis, Christine L.

Publication type:

Article

Activation by NarL at the Escherichia coli ogt promoter.

Published in:

Biochemical Journal, 2020, v. 477, n. 15, p. 2807, doi. 10.1042/BCJ20200408

By:

Ruanto, Patcharawarin;
Chismon, David L.;
Hothersall, Joanne;
Godfrey, Rita E.;
Lee, David J.;
Busby, Stephen J. W.;
Browning, Douglas F.

Publication type:

Article

A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018031

By:

Fukuda, Daisuke;
Haines, Anthony S.;
Song, Zhongshu;
Murphy, Annabel C.;
Hothersall, Joanne;
Stephens, Elton R.;
Gurney, Rachel;
Cox, Russell J.;
Crosby, John;
Willis, Christine L.;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

Back Cover: Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics (Angew. Chem. Int. Ed. 14/2017).

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 14, p. 4066, doi. 10.1002/anie.201702123

By:

Gao, Shu-Shan;
Wang, Luoyi;
Song, Zhongshu;
Crump, Matthew P.;
Simpson, Thomas J.;
Willis, Christine L.;
Cox, Russell J.;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Thomas, Christopher M.;
Race, Paul R.

Publication type:

Article

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 14, p. 3930, doi. 10.1002/anie.201611590

By:

Gao, Shu-Shan;
Wang, Luoyi;
Song, Zhongshu;
Crump, Matthew P.;
Simpson, Thomas J.;
Willis, Christine L.;
Cox, Russell J.;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Thomas, Christopher M.;
Race, Paul R.

Publication type:

Article

A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 11, p. 685, doi. 10.1038/nchembio.1342

By:

Haines, Anthony S;
Dong, Xu;
Song, Zhongshu;
Farmer, Rohit;
Williams, Christopher;
Hothersall, Joanne;
Płoskoń, Eliza;
Wattana-amorn, Pakorn;
Stephens, Elton R;
Yamada, Erika;
Gurney, Rachel;
Takebayashi, Yuiko;
Masschelein, Joleen;
Cox, Russell J;
Lavigne, Rob;
Willis, Christine L;
Simpson, Thomas J;
Crosby, John;
Winn, Peter J;
Thomas, Christopher M

Publication type:

Article