Works matching AU Hoskin, David W.

Results: 46

Thy‑1 stimulation of mouse T cells induces a delayed T cell receptor‑like signal that results in Ca2+‑independent cytotoxicity.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 4, p. 5683, doi. 10.3892/mmr.2017.7242

By:

FURLONG, SUZANNE;
COOMBS, MELANIE R. POWER;
HOSKIN, DAVID W.

Publication type:

Article

DIBI, a novel 3-hydroxypyridin-4-one chelator iron-binding polymer, inhibits breast cancer cell growth and functions as a chemosensitizer by promoting S-phase DNA damage.

Published in:

BioMetals, 2019, v. 32, n. 6, p. 909, doi. 10.1007/s10534-019-00222-3

By:

Greenshields, Anna L.;
Power Coombs, Melanie R.;
Fernando, Wasundara;
Holbein, Bruce E.;
Hoskin, David W.

Publication type:

Article

Myricetin‐induced oxidative stress suppresses murine T lymphocyte activation.

Published in:

Cell Biology International, 2018, v. 42, n. 8, p. 1069, doi. 10.1002/cbin.10977

By:

Ghassemi‐rad, Javad;
Maleki, Mahdis;
Knickle, Allison F.;
Hoskin, David W.

Publication type:

Article

Suppression of NNK Metabolism by Anthocyanin-Rich Haskap Berry Supplementation Through Modulation of P450 Enzymes.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 12, p. 1615, doi. 10.3390/ph17121615

By:

Amararathna, Madumani;
Hoskin, David W.;
Goralski, Kerry B.;
Rupasinghe, H. P. Vasantha

Publication type:

Article

The Natural Alkaloid Piperlongumine Inhibits Metastatic Activity and Epithelial-to-Mesenchymal Transition of Triple-Negative Mammary Carcinoma Cells.

Published in:

Nutrition & Cancer, 2021, v. 73, n. 11/12, p. 2397, doi. 10.1080/01635581.2020.1825755

By:

Delaney, Leanne M.;
Farias, Nathan;
Ghassemi Rad, Javad;
Fernando, Wasundara;
Annan, Henry;
Hoskin, David W.

Publication type:

Article

Iron Overload and Breast Cancer: Iron Chelation as a Potential Therapeutic Approach.

Published in:

Life (2075-1729), 2022, v. 12, n. 7, p. 963, doi. 10.3390/life12070963

By:

Islam, Sufia;
Hoque, Nazia;
Nasrin, Nishat;
Hossain, Mehnaz;
Rizwan, Farhana;
Biswas, Kushal;
Asaduzzaman, Muhammad;
Rahman, Sabera;
Hoskin, David W.;
Sultana, Saki;
Lehmann, Christian

Publication type:

Article

Pleurocidin-family cationic antimicrobial peptides mediate lysis of multiple myeloma cells and impair the growth of multiple myeloma xenografts.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 10, p. 2255, doi. 10.3109/10428194.2013.770847

By:

Hilchie, Ashley L.;
Conrad, David M.;
Power Coombs, Melanie R.;
Zemlak, Tyler;
Doucette, Carolyn D.;
Liwski, Robert S.;
Hoskin, David W.

Publication type:

Article

Phloridzin Docosahexaenoate Inhibits Spheroid Formation by Breast Cancer Stem Cells and Exhibits Cytotoxic Effects against Paclitaxel-Resistant Triple Negative Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14577, doi. 10.3390/ijms241914577

By:

Fernando, Wasundara;
Clark, Rikki F.;
Rupasinghe, H. P. Vasantha;
Hoskin, David W.;
Coombs, Melanie R. Power

Publication type:

Article

Chemopreventive Effect of Dietary Anthocyanins against Gastrointestinal Cancers: A Review of Recent Advances and Perspectives.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6555, doi. 10.3390/ijms21186555

By:

Dharmawansa, K.V. Surangi;
Hoskin, David W.;
Rupasinghe, H. P. Vasantha

Publication type:

Article

Impaired Interleukin-2 Synthesis and T Cell Proliferation Following Antibody-mediated CD3 and CD2 or CD28 Cross-linking in Trans: Evidence that T Cell Activation Requires the Engagement of Costimulatory Molecules Within the Immunological Synapse.

Published in:

Immunological Investigations, 2008, v. 37, n. 1, p. 63, doi. 10.1080/08820130701555035

By:

Watson, Carrie L.;
Furlong, Suzanne J.;
Hoskin, David W.

Publication type:

Article

Regulatory Role of CD8 in Major Histocompatibility Complex-Unrestricted Tumoricidal Activity of Mouse T Cells Activated with Anti-CD3 Monoclonal Antibody.

Published in:

Immunological Investigations, 1997, v. 26, n. 5-7, p. 601, doi. 10.3109/08820139709088544

By:

Stewart, B. Hope;
Hoskin, David W.

Publication type:

Article

Regulation of Cytokine Polarization and T Cell Recruitment to Inflamed Paws in Mouse Collagen-Induced Arthritis by the Chemokine Receptor CXCR6.

Published in:

Arthritis & Rheumatology, 2014, v. 66, n. 11, p. 3001, doi. 10.1002/art.38816

By:

Slauenwhite, Drew;
Gebremeskel, Simon;
Doucette, Carolyn D.;
Hoskin, David W.;
Johnston, Brent

Publication type:

Article

Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis.

Published in:

Acta Neuropathologica Communications, 2018, v. 6, p. 1, doi. 10.1186/s40478-017-0506-9

By:

Warford, Jordan R.;
Lamport, Anna-Claire;
Clements, Derek R.;
Malone, Alicia;
Kennedy, Barry E.;
Kim, Youra;
Gujar, Shashi A.;
Hoskin, David W.;
Easton, Alexander S.

Publication type:

Article

Treatment of the P815 murine mastocytoma with cisplatin or etoposide up-regulates cell-surface Fas (CD95) expression and increases sensitivity to anti-Fas antibody-mediated cytotoxicity and to lysis by anti-CD3-activated killer-T cells.

Published in:

International Journal of Cancer, 1997, v. 73, n. 3, p. 416, doi. 10.1002/(SICI)1097-0215(19971104)73:3<416::AID-IJC17>3.0.CO;2-A

By:

Williams, Brent A.;
Makrigiannis, Andrew P.;
Blay, Jonathan;
Hoskin, David W.

Publication type:

Article

Adenosine as a possible inhibitor of killer T-cell activation in the microenvironment of solid tumours.

Published in:

International Journal of Cancer, 1994, v. 59, n. 6, p. 854, doi. 10.1002/ijc.2910590625

By:

Hoskin, David W.;
Reynolds, Teresa;
Blay, Jonathan

Publication type:

Article

Retinoic acid and arsenic trioxide induce lasting differentiation and demethylation of target genes in APL cells.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45982-7

By:

Huynh, Thomas T.;
Sultan, Mohammad;
Vidovic, Dejan;
Dean, Cheryl A.;
Cruickshank, Brianne M.;
Lee, Kristen;
Loung, Chao-Yu;
Holloway, Ryan W.;
Hoskin, David W.;
Waisman, David M.;
Weaver, Ian C. G.;
Marcato, Paola

Publication type:

Article

TRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-40330-1

By:

Almasi, Shekoufeh;
Sterea, Andra M.;
Fernando, Wasundara;
Clements, Derek R.;
Marcato, Paola;
Hoskin, David W.;
Gujar, Shashi;
El Hiani, Yassine

Publication type:

Article

Adenosine acts through an A.

Published in:

International Journal of Cancer, 2002, v. 99, n. 3, p. 386, doi. 10.1002/ijc.10325

By:

Hoskin, David W.;
Butler, Jared J.;
Drapeau, Dennis;
Haeryfar, S.M. Mansour;
Blay, Jonathan

Publication type:

Article

The Dietary Flavonoid Fisetin Causes Cell Cycle Arrest, Caspase-Dependent Apoptosis, and Enhanced Cytotoxicity of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells.

Published in:

Journal of Cellular Biochemistry, 2016, v. 117, n. 8, p. 1913, doi. 10.1002/jcb.25490

By:

Smith, Matthew L.;
Murphy, Kaylee;
Doucette, Carolyn D.;
Greenshields, Anna L.;
Hoskin, David W.

Publication type:

Article

Piperine From Black Pepper Inhibits Activation-Induced Proliferation and Effector Function of T Lymphocytes.

Published in:

Journal of Cellular Biochemistry, 2015, v. 116, n. 11, p. 2577, doi. 10.1002/jcb.25202

By:

Doucette, Carolyn D.;
Rodgers, Gemma;
Liwski, Robert S.;
Hoskin, David W.

Publication type:

Article

Exposure to paclitaxel or vinblastine down-regulates CD11a and CD54 expression by P815 mastocytoma cells and renders the tumor cells resistant to killing by nonspecific cytotoxic T lymphocytes induced with anti-CD3 antibody.

Published in:

Cancer Immunology, Immunotherapy, 2003, v. 52, n. 3, p. 185, doi. 10.1007/s00262-002-0357-4

By:

Zhao, Chuanli;
Morgan, Max;
Haeryfar, S.M. Mansour;
Blay, Jonathan;
Hoskin, David W.

Publication type:

Article

Phloridzin Docosahexaenoate, an Omega-3 Fatty Acid Ester of a Flavonoid Precursor, Inhibits Angiogenesis by Suppressing Endothelial Cell Proliferation, Migration, and Differentiation.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 7, p. 769, doi. 10.3390/biom14070769

By:

Fernando, Wasundara;
MacLean, Emma;
Monro, Susan;
Power Coombs, Melanie R.;
Marcato, Paola;
Rupasinghe, H. P. Vasantha;
Hoskin, David W.

Publication type:

Article

MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 9, p. 1220, doi. 10.3390/biom10091220

By:

Hilchie, Ashley L.;
Gill, Erin E.;
Coombs, Melanie R. Power;
Falsafi, Reza;
Hancock, Robert E. W.;
Hoskin, David W.

Publication type:

Article

Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate.

Published in:

Molecular Carcinogenesis, 2017, v. 56, n. 1, p. 75, doi. 10.1002/mc.22474

By:

Greenshields, Anna L.;
Shepherd, Trevor G.;
Hoskin, David W.

Publication type:

Article

Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress.

Published in:

Molecular Carcinogenesis, 2015, v. 54, n. 10, p. 1070, doi. 10.1002/mc.22176

By:

Yaffe, Paul B.;
Power Coombs, Melanie R.;
Doucette, Carolyn D.;
Walsh, Mark;
Hoskin, David W.

Publication type:

Article

Pleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts.

Published in:

2011

By:

Hilchie, Ashley L;
Doucette, Carolyn D;
Pinto, Devanand M;
Patrzykat, Aleksander;
Douglas, Susan;
Hoskin, David W

Publication type:

journal article

Metabolism and pharmacokinetics of a novel polyphenol fatty acid ester phloridzin docosahexaenoate in Balb/c female mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-78369-0

By:

Fernando, Wasundara;
Goralski, Kerry B.;
Hoskin, David W.;
Rupasinghe, H. P. Vasantha

Publication type:

Article

Myeloid-derived suppressor cell depletion therapy targets IL-17A-expressing mammary carcinomas.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-70231-7

By:

Dawod, Bassel;
Liu, Jinghua;
Gebremeskel, Simon;
Yan, Chi;
Sappong, Antonia;
Johnston, Brent;
Hoskin, David W.;
Marshall, Jean S.;
Wang, Jun

Publication type:

Article

Oncogenic BRAF in Cutaneous Melanoma: Mutational Status and Implications for Targeted Therapy.

Published in:

Canadian Journal of Pathology, 2010, v. 2, n. 2, p. 27

By:

Watson, Jane L.;
Yaffe, Paul B.;
Walsh, Mark;
Giacomantonio, Carman A.;
Hoskin, David W.

Publication type:

Article

4T1 Murine Mammary Carcinoma Cells Enhance Macrophage-Mediated Innate Inflammatory Responses.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133385

By:

Madera, Laurence;
Greenshields, Anna;
Coombs, Melanie R. Power;
Hoskin, David W.

Publication type:

Article

Murine Experimental Autoimmune Encephalomyelitis Is Diminished by Treatment with the Angiogenesis Inhibitors B20-4.1.1 and Angiostatin (K1-3).

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089770

By:

MacMillan, Carolyn J.;
Doucette, Carolyn D.;
Warford, Jordan;
Furlong, Suzanne J.;
Hoskin, David W.;
Easton, Alexander S.

Publication type:

Article

Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.

Published in:

Molecular Carcinogenesis, 2010, v. 49, n. 1, p. 13, doi. 10.1002/mc.20571

By:

Watson, Jane L.;
Greenshields, Anna;
Hill, Richard;
Hilchie, Ashley;
Lee, Patrick W.;
Giacomantonio, Carman A.;
Hoskin, David W.

Publication type:

Article

Docosahexaenoic acid-acylated phloridzin, a novel polyphenol fatty acid ester derivative, is cytotoxic to breast cancer cells.

Published in:

Carcinogenesis, 2016, v. 37, n. 10, p. 1004, doi. 10.1093/carcin/bgw087

By:

Fernando, Wasundara;
Coombs, Melanie R. Power;
Hoskin, David W.;
Rupasinghe, H. P. Vasantha

Publication type:

Article

Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc.

Published in:

Journal of Cellular Physiology, 2013, v. 228, n. 9, p. 1884, doi. 10.1002/jcp.24350

By:

Kim, Jae‐Sung;
Ellman, Michael B.;
Yan, Dongyao;
An, Howard S.;
KC, Ranjan;
Li, Xin;
Chen, Di;
Xiao, Guozhi;
Cs‐Szabo, Gabriella;
Hoskin, David W.;
Buechter, Doug D.;
Van Wijnen, Andre J.;
Im, Hee‐Jeong

Publication type:

Article

Lactoferricin mediates anabolic and anti-catabolic effects in the intervertebral disc.

Published in:

Journal of Cellular Physiology, 2012, v. 227, n. 4, p. 1512, doi. 10.1002/jcp.22867

By:

Kim, Jae-Sung;
Ellman, Michael B.;
An, Howard S.;
Yan, Dongyao;
van Wijnen, Andre J.;
Murphy, Gillian;
Hoskin, David W.;
Im, Hee-Jeong

Publication type:

Article

Piperine, a Pungent Alkaloid from Black Pepper, Inhibits B Lymphocyte Activation and Effector Functions.

Published in:

2017

By:

Soutar, David A.;
Doucette, Carolyn D.;
Liwski, Robert S.;
Hoskin, David W.

Publication type:

journal article

Differential Inhibition of T Lymphocyte Proliferation and Cytokine Synthesis by [6]-Gingerol, [8]-Gingerol, and [10]-Gingerol.

Published in:

2015

By:

Bernard, Megan;
Furlong, Suzanne J.;
Power Coombs, Melanie R.;
Hoskin, David W.

Publication type:

journal article

Cyanidin-3-O-Glucoside-Rich Haskap Berry Administration Suppresses Carcinogen-Induced Lung Tumorigenesis in A/JCr Mice.

Published in:

Molecules, 2020, v. 25, n. 17, p. 3823, doi. 10.3390/molecules25173823

By:

Amararathna, Madumani;
Hoskin, David W.;
Rupasinghe, H. P. Vasantha;
Sonvico, Fabio

Publication type:

Article

Apple Peel Flavonoid Fraction 4 Suppresses Breast Cancer Cell Growth by Cytostatic and Cytotoxic Mechanisms.

Published in:

Molecules, 2019, v. 24, n. 18, p. 3335, doi. 10.3390/molecules24183335

By:

Loung, Chao-Yu;
Fernando, Wasundara;
Rupasinghe, H.P. Vasantha;
Hoskin, David W.

Publication type:

Article

Dual Antimicrobial and Antiproliferative Activity of TcPaSK Peptide Derived from a Tribolium castaneum Insect Defensin.

Published in:

Microorganisms, 2021, v. 9, n. 2, p. 222, doi. 10.3390/microorganisms9020222

By:

Robles-Fort, Aida;
García-Robles, Inmaculada;
Fernando, Wasundara;
Hoskin, David W.;
Rausell, Carolina;
Real, María Dolores;
Hilpert, Kai

Publication type:

Article

Induction of CD4+CD25+Foxp3− regulatory T cells by Thy-1 stimulation of CD4+ T cells.

Published in:

Immunology & Cell Biology, 2012, v. 90, n. 2, p. 248, doi. 10.1038/icb.2011.33

By:

Conrad, David M;
Coombs, Melanie R Power;
Furlong, Suzanne J;
Forward, Nicholas A;
Hoskin, David W

Publication type:

Article

Antibody blockade of Thy-1 (CD90) impairsmouse cytotoxic T lymphocyte induction by anti-CD3 monoclonal antibody.

Published in:

Immunology & Cell Biology, 2005, v. 83, n. 4, p. 352, doi. 10.1111/j.1440-1711.2005.01342.x

By:

Haeryfar, S. M. Mansour;
Conrad, David M.;
Musgrave, Bruce L.;
Hoskin, David W.

Publication type:

Article

Editorial: Immune Modulation by Flavonoids.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.899577

By:

Hoskin, David W.;
Coombs, Melanie R. Power

Publication type:

Article

Iron Withdrawal with DIBI, a Novel 3-Hydroxypyridin-4-One Chelator Iron-Binding Polymer, Attenuates Macrophage Inflammatory Responses.

Published in:

Advanced Pharmaceutical Bulletin, 2023, v. 13, n. 2, p. 368, doi. 10.34172/apb.2023.040

By:

Ghassemi-Rad, Javad;
Fernando, Wasundara;
Holbein, Bruce E.;
Hoskin, David W.

Publication type:

Article

10-Gingerol Inhibits Ovarian Cancer Cell Growth by Inducing G2 Arrest.

Published in:

Advanced Pharmaceutical Bulletin, 2019, v. 9, n. 4, p. 685, doi. 10.15171/apb.2019.080

By:

Rasmussen, Andrea;
Murphy, Kaylee;
Hoskin, David W.

Publication type:

Article

Anthocyanin Encapsulated Nanoparticles as a Pulmonary Delivery System.

Published in:

Oxidative Medicine & Cellular Longevity, 2022, p. 1, doi. 10.1155/2022/1422929

By:

Amararathna, Madumani;
Hoskin, David W.;
Rupasinghe, H. P. Vasantha

Publication type:

Article