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Educational paper. The development of new therapies for pediatric oncology.
Published in:
2011
By:
- Horton, Terzah M.;
- Berg, Stacey L.
Publication type:
journal article
DNA Damage Response−Related Proteins Are Prognostic for Outcome in Both Adult and Pediatric Acute Myelogenous Leukemia Patients: Samples from Adults and from Children Enrolled in a Children's Oncology Group Study.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5898, doi. 10.3390/ijms24065898
By:
- Hubner, Stefan E.;
- de Camargo Magalhães, Eduardo S.;
- Hoff, Fieke W.;
- Brown, Brandon D.;
- Qiu, Yihua;
- Horton, Terzah M.;
- Kornblau, Steven M.
Publication type:
Article
Reverse Phase Protein Array Profiling Identifies Recurrent Protein Expression Patterns of DNA Damage-Related Proteins across Acute and Chronic Leukemia: Samples from Adults and the Children's Oncology Group.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5460, doi. 10.3390/ijms24065460
By:
- Hoff, Fieke W.;
- Griffen, Ti'ara L.;
- Brown, Brandon D.;
- Horton, Terzah M.;
- Burger, Jan;
- Wierda, William;
- Hubner, Stefan E.;
- Qiu, Yihua;
- Kornblau, Steven M.
Publication type:
Article
The Anti-Tumor Activity of the NEDD8 Inhibitor Pevonedistat in Neuroblastoma.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6565, doi. 10.3390/ijms22126565
By:
- Foster, Jennifer H.;
- Barbieri, Eveline;
- Zhang, Linna;
- Scorsone, Kathleen A.;
- Moreno-Smith, Myrthala;
- Zage, Peter;
- Horton, Terzah M.
Publication type:
Article
Inhibition of the Sec61 translocon overcomes cytokine‐induced glucocorticoid resistance in T‐cell acute lymphoblastic leukaemia.
Published in:
British Journal of Haematology, 2022, v. 198, n. 1, p. 137, doi. 10.1111/bjh.18181
By:
- Meyer, Lauren K.;
- Delgado‐Martin, Cristina;
- Sharp, Phillip P.;
- Huang, Benjamin J.;
- McMinn, Dustin;
- Vincent, Tiffaney L.;
- Ryan, Theresa;
- Horton, Terzah M.;
- Wood, Brent L.;
- Teachey, David T.;
- Taunton, Jack;
- Kirk, Christopher J.;
- Hermiston, Michelle L.
Publication type:
Article
Bortezomib reinduction chemotherapy in high‐risk ALL in first relapse: a report from the Children's Oncology Group.
Published in:
British Journal of Haematology, 2019, v. 186, n. 2, p. 274, doi. 10.1111/bjh.15919
By:
- Horton, Terzah M.;
- Whitlock, James A.;
- Lu, Xiaomin;
- O'Brien, Maureen M.;
- Borowitz, Michael J.;
- Devidas, Meenakshi;
- Raetz, Elizabeth A.;
- Brown, Patrick A.;
- Carroll, William L.;
- Hunger, Stephen P.
Publication type:
Article
A phase 2 study of bortezomib in combination with ifosfamide/vinorelbine in paediatric patients and young adults with refractory/recurrent Hodgkin lymphoma: a Children's Oncology Group study.
Published in:
British Journal of Haematology, 2015, v. 170, n. 1, p. 118, doi. 10.1111/bjh.13388
By:
- Horton, Terzah M.;
- Drachtman, Richard A.;
- Chen, Lu;
- Cole, Peter D.;
- McCarten, Kathleen;
- Voss, Stephan;
- Guillerman, Robert P.;
- Buxton, Allen;
- Howard, Scott C.;
- Hogan, Shirley M.;
- Sheehan, Andrea M.;
- López‐Terrada, Dolores;
- Mrazek, Matthew D.;
- Agrawal, Neeraj;
- Wu, Meng‐Fen;
- Liu, Hao;
- De Alarcon, Pedro A.;
- Trippet, Tanya M.;
- Schwartz, Cindy L.
Publication type:
Article
Integrin signaling is critical for myeloid-mediated support of T-cell acute lymphoblastic leukemia.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41925-z
By:
- Lyu, Aram;
- Humphrey, Ryan S.;
- Nam, Seo Hee;
- Durham, Tyler A.;
- Hu, Zicheng;
- Arasappan, Dhivya;
- Horton, Terzah M.;
- Ehrlich, Lauren I. R.
Publication type:
Article
Chromatin Profiles Are Prognostic of Clinical Response to Bortezomib-Containing Chemotherapy in Pediatric Acute Myeloid Leukemia: Results from the COG AAML1031 Trial.
Published in:
Cancers, 2024, v. 16, n. 8, p. 1448, doi. 10.3390/cancers16081448
By:
- van Dijk, Anneke D.;
- Hoff, Fieke W.;
- Qiu, Yihua;
- Hubner, Stefan E.;
- Go, Robin L.;
- Ruvolo, Vivian R.;
- Leonti, Amanda R.;
- Gerbing, Robert B.;
- Gamis, Alan S.;
- Aplenc, Richard;
- Kolb, Edward A.;
- Alonzo, Todd A.;
- Meshinchi, Soheil;
- de Bont, Eveline S. J. M.;
- Horton, Terzah M.;
- Kornblau, Steven M.
Publication type:
Article
Defining the Inflammatory Plasma Proteome in Pediatric Hodgkin Lymphoma.
Published in:
Cancers, 2020, v. 12, n. 12, p. 3603, doi. 10.3390/cancers12123603
By:
- Agrusa, Jennifer E.;
- Scull, Brooks P.;
- Abhyankar, Harshal A.;
- Lin, Howard;
- Ozuah, Nmazuo W.;
- Chakraborty, Rikhia;
- Eckstein, Olive S.;
- Gulati, Nitya;
- Fattah, Elmoataz Abdel;
- El-Mallawany, Nader K.;
- Rouce, Rayne H.;
- Dreyer, ZoAnn E.;
- Brackett, Julienne;
- Margolin, Judith F.;
- Lubega, Joseph;
- Horton, Terzah M.;
- Bollard, Catherine M.;
- Gramatges, M. Monica;
- Kamdar, Kala Y.;
- McClain, Kenneth L.
Publication type:
Article
Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes.
Published in:
2020
By:
- Meyer, Lauren K.;
- Huang, Benjamin J.;
- Delgado-Martin, Cristina;
- Roy, Ritu P.;
- Hechmer, Aaron;
- Wandler, Anica M.;
- Vincent, Tiffaney L.;
- Fortina, Paolo;
- Olshen, Adam B.;
- Wood, Brent L.;
- Horton, Terzah M.;
- Shannon, Kevin M.;
- Teachey, David T.;
- Hermiston, Michelle L.
Publication type:
journal article
The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.
Published in:
Science Translational Medicine, 2020, v. 12, n. 538, p. 1, doi. 10.1126/scitranslmed.aaz8264
By:
- Mirali, Sara;
- Botham, Aaron;
- Voisin, Veronique;
- Xu, Changjiang;
- St-Germain, Jonathan;
- Sharon, David;
- Hoff, Fieke W.;
- Qiu, Yihua;
- Hurren, Rose;
- Gronda, Marcela;
- Jitkova, Yulia;
- Nachmias, Boaz;
- MacLean, Neil;
- Wang, Xiaoming;
- Arruda, Andrea;
- Minden, Mark D.;
- Horton, Terzah M.;
- Kornblau, Steven M.;
- Chan, Steven M.;
- Bader, Gary D.
Publication type:
Article
Bortezomib interactions with chemotherapy agents in acute leukemia in vitro.
Published in:
Cancer Chemotherapy & Pharmacology, 2006, v. 58, n. 1, p. 13, doi. 10.1007/s00280-005-0135-z
By:
- Horton, Terzah M.;
- Gannavarapu, Anurhadha;
- Blaney, Susan M.;
- D'Argenio, David Z.;
- Plon, Sharon E.;
- Berg, Stacey L.
Publication type:
Article
Feasibility of pevonedistat combined with azacitidine, fludarabine, cytarabine in pediatric relapsed/refractory AML: Results from COG ADVL1712.
Published in:
Pediatric Blood & Cancer, 2023, v. 70, n. 12, p. 1, doi. 10.1002/pbc.30672
By:
- Tarlock, Katherine;
- Liu, Xiaowei;
- Minard, Charles G.;
- Isikwei, Emasenyie A.;
- Reid, Joel M.;
- Horton, Terzah M.;
- Fox, Elizabeth;
- Weigel, Brenda J.;
- Cooper, Todd
Publication type:
Article
Ethnic disparities relative to disease features and outcomes in children with acute myeloid leukemia.
Published in:
2017
By:
- Gramatges, M. Monica;
- Deshpande, Aditya;
- Lupo, Philip J.;
- Rau, Rachel E.;
- Redell, Michele L.;
- Horton, Terzah M.;
- Scheurer, Michael E.;
- Rabin, Karen R.
Publication type:
journal article
A Phase 2 study of bortezomib combined with either idarubicin/cytarabine or cytarabine/etoposide in children with relapsed, refractory or secondary acute myeloid leukemia: A report from the Children's Oncology Group.
Published in:
Pediatric Blood & Cancer, 2014, v. 61, n. 10, p. 1754, doi. 10.1002/pbc.25117
By:
- Horton, Terzah M.;
- Perentesis, John P.;
- Gamis, Alan S.;
- Alonzo, Todd A.;
- Gerbing, Robert B.;
- Ballard, Jennifer;
- Adlard, Kathleen;
- Howard, Dianna S.;
- Smith, Franklin O.;
- Jenkins, Gaye;
- Kelder, Angelé;
- Schuurhuis, Gerrit J.;
- Moscow, Jeffrey A.
Publication type:
Article
Novel mitochondrial DNA deletion found in a renal cell carcinoma.
Published in:
Genes, Chromosomes & Cancer, 1996, v. 15, n. 2, p. 95, doi. 10.1002/(SICI)1098-2264(199602)15:2<95::AID-GCC3>3.0.CO;2-Z
By:
- Horton, Terzah M.;
- Petros, John A.;
- Heddi, Abdelaziz;
- Shoffner, John;
- Kaufman, Allan E.;
- Graham, Sam D.;
- Gramlich, Terry;
- Wallace, Douglas C.
Publication type:
Article
Analysis of NF-?B Pathway Proteins in Pediatric Hodgkin Lymphoma: Correlations with EBV Status and Clinical Outcome--A Children's Oncology Group Study.
Published in:
Lymphoma (2090309X), 2012, p. 1, doi. 10.1155/2012/341629
By:
- Horton, Terzah M.;
- Sheehan, Andrea M.;
- López-Terrada, Dolores;
- Hutchison, Robert E.;
- Narendra, Sonia;
- Wu, Meng-Fen;
- Hao Liu
Publication type:
Article
Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy.
Published in:
Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0312-z
By:
- Niewerth, Denise;
- Kaspers, Gertjan J. L.;
- van Meerloo, Johan;
- Cloos, Jacqueline;
- Jansen, Gerrit;
- Zweegman, Sonja;
- Jenkins, Gaye;
- Horton, Terzah M.;
- Whitlock, James A.;
- Hunger, Stephen P.;
- Xiaomin Lu;
- Alonzo, Todd A.;
- van de Ven, Peter M.
Publication type:
Article
Population Pharmacokinetic Analysis of Bortezomib in Pediatric Leukemia Patients: Model-Based Support for Body Surface Area-Based Dosing Over the 2- to 16-Year Age Range.
Published in:
Journal of Clinical Pharmacology, 2017, v. 57, n. 9, p. 1183, doi. 10.1002/jcph.906
By:
- Hanley, Michael J.;
- Mould, Diane R.;
- Taylor, Timothy J.;
- Gupta, Neeraj;
- Suryanarayan, Kaveri;
- Neuwirth, Rachel;
- Esseltine, Dixie‐Lee;
- Horton, Terzah M.;
- Aplenc, Richard;
- Alonzo, Todd A.;
- Lu, Xiaomin;
- Milton, Ashley;
- Venkatakrishnan, Karthik
Publication type:
Article
AAML0523: A report from the Children's Oncology Group on the efficacy of clofarabine in combination with cytarabine in pediatric patients with recurrent acute myeloid leukemia.
Published in:
Cancer (0008543X), 2014, v. 120, n. 16, p. 2482, doi. 10.1002/cncr.28674
By:
- Cooper, Todd M.;
- Alonzo, Todd A.;
- Gerbing, Robert B.;
- Perentesis, John P.;
- Whitlock, James A.;
- Taub, Jeffrey W.;
- Horton, Terzah M.;
- Gamis, Alan S.;
- Meshinchi, Soheil;
- Loken, Michael R.;
- Razzouk, Bassem I.
Publication type:
Article
A phase I trial of vorinostat and bortezomib in children with refractory or recurrent solid tumors: A Children's Oncology Group phase I consortium study (ADVL0916).
Published in:
Pediatric Blood & Cancer, 2013, v. 60, n. 3, p. 390, doi. 10.1002/pbc.24271
By:
- Muscal, Jodi A.;
- Thompson, Patrick A.;
- Horton, Terzah M.;
- Ingle, Ashish M.;
- Ahern, Charlotte H.;
- McGovern, Renee M.;
- Reid, Joel M.;
- Ames, Matthew M.;
- Espinoza‐Delgado, Igor;
- Weigel, Brenda J.;
- Blaney, Susan M.
Publication type:
Article
Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): Review from an international consensus conference.
Published in:
Pediatric Blood & Cancer, 2010, v. 54, n. 7, p. 872, doi. 10.1002/pbc.22414
By:
- Horton, Terzah M.;
- Sposto, Richard;
- Brown, Patrick;
- Reynolds, C. Patrick;
- Hunger, Stephen P.;
- Winick, Naomi J.;
- Raetz, Elizabeth A.;
- Carroll, William L.;
- Arceci, Robert J.;
- Borowitz, Michael J.;
- Gaynon, Paul S.;
- Gore, Lia;
- Jeha, Sima;
- Maurer, Barry J.;
- Siegel, Stuart E.;
- Biondi, Andrea;
- Kearns, Pamela R.;
- Narendran, Aru;
- Silverman, Lewis B.;
- Smith, Malcolm A.
Publication type:
Article
A Phase 1 and pharmacokinetic clinical trial of paclitaxel for the treatment of refractory leukemia in children: A Children's Oncology Group study.
Published in:
Pediatric Blood & Cancer, 2008, v. 50, n. 4, p. 788, doi. 10.1002/pbc.21310
By:
- Horton, Terzah M.;
- Ames, Matthew M.;
- Reid, Joel M.;
- Krailo, Mark D.;
- Pendergrass, Thomas;
- Mosher, Revonda;
- Reaman, Gregory H.;
- Seibel, Nita L.
Publication type:
Article
Valosin‐containing protein (VCP/p97) is prognostically unfavorable in pediatric AML, and negatively correlates with unfolded protein response proteins IRE1 and GRP78: A report from the Children's Oncology Group.
Published in:
Proteomics - Clinical Applications, 2023, v. 17, n. 6, p. 1, doi. 10.1002/prca.202200109
By:
- Hoff, Fieke W.;
- Qiu, Yihua;
- Brown, Brandon D.;
- Gerbing, Robert B.;
- Leonti, Amanda R.;
- Ries, Rhonda E.;
- Gamis, Alan S.;
- Aplenc, Richard;
- Kolb, Edward Anders;
- Alonzo, Todd A.;
- Meshinchi, Soheil;
- Jenkins, Gaye N.;
- Horton, Terzah M.;
- Kornblau, Steven M.
Publication type:
Article
Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF‐κB subunit RelA.
Published in:
Proteomics - Clinical Applications, 2022, v. 16, n. 2, p. 1, doi. 10.1002/prca.202100072
By:
- van Dijk, Anneke D.;
- Hoff, Fieke W.;
- Qiu, Yihua;
- Gerbing, Robert B.;
- Gamis, Alan S.;
- Aplenc, Richard;
- Kolb, E. Anders;
- Alonzo, Todd A.;
- Meshinchi, Soheil;
- Jenkins, Gaye N.;
- de Bont, Eveline S. J. M.;
- Kornblau, Steven M.;
- Horton, Terzah M.
Publication type:
Article

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