Works by Horlbeck, Max

Results: 12

Cellular response to small molecules that selectively stall protein synthesis by the ribosome.

Published in:

PLoS Genetics, 2019, v. 15, n. 3, p. 1, doi. 10.1371/journal.pgen.1008057

By:

Liaud, Nadège;
Horlbeck, Max A.;
Gilbert, Luke A.;
Gjoni, Ketrin;
Weissman, Jonathan S.;
Cate, Jamie H. D.

Publication type:

Article

Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.67624

By:

Le Vasseur, Maxence;
Friedman, Jonathan;
Jost, Marco;
Jiawei Xu;
Yamada, Justin;
Kampmann, Martin;
Horlbeck, Max A.;
Salemi, Michelle R.;
Phinney, Brett S.;
Weissman, Jonathan S.;
Nunnari, Jodi

Publication type:

Article

Characterization of Sirtuin Proteins using RasMol-RP and Three Dimensional Modeling.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1036

By:

O'Mara, Deirdre;
Vershon, Andrew K.;
Herman, Timothy;
Conti, Brooke;
Fernando, Michael;
Lashley, Danielle;
Li, Audrey;
Paton, Sarah;
White, James;
Horlbeck, Max

Publication type:

Article

Single-cell analysis of long non-coding RNAs in the developing human neocortex.

Published in:

Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-0932-1

By:

Liu, Siyuan John;
Nowakowski, Tomasz J.;
Pollen, Alex A.;
Lui, Jan H.;
Horlbeck, Max A.;
Attenello, Frank J.;
He, Daniel;
Weissman, Jonathan S.;
Kriegstein, Arnold R.;
Diaz, Aaron A.;
Lim, Daniel A.

Publication type:

Article

A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.

Published in:

PLoS Biology, 2018, v. 16, n. 8, p. 1, doi. 10.1371/journal.pbio.2004624

By:

Mendelsohn, Bryce A.;
Bennett, Neal K.;
Darch, Maxwell A.;
Yu, Katharine;
Nguyen, Mai K.;
Pucciarelli, Daniela;
Nelson, Maxine;
Horlbeck, Max A.;
Gilbert, Luke A.;
Hyun, William;
Kampmann, Martin;
Nakamura, Jean L.;
Nakamura, Ken

Publication type:

Article

Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes.

Published in:

2020

By:

Horlbeck, Max A.;
Liu, S. John;
Chang, Howard Y.;
Lim, Daniel A.;
Weissman, Jonathan S.

Publication type:

Letter

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs.

Published in:

Nature Biotechnology, 2020, v. 38, n. 3, p. 355, doi. 10.1038/s41587-019-0387-5

By:

Jost, Marco;
Santos, Daniel A.;
Saunders, Reuben A.;
Horlbeck, Max A.;
Hawkins, John S.;
Scaria, Sonia M.;
Norman, Thomas M.;
Hussmann, Jeffrey A.;
Liem, Christina R.;
Gross, Carol A.;
Weissman, Jonathan S.

Publication type:

Article

New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells.

Published in:

Journal of Cell Biology, 2019, v. 218, n. 11, p. 3861, doi. 10.1083/jcb.201902028

By:

Bassaganyas, Laia;
Popa, Stephanie J.;
Horlbeck, Max;
Puri, Claudia;
Stewart, Sarah E.;
Campelo, Felix;
Ashok, Anupama;
Butnaru, Cristian M.;
Brouwers, Nathalie;
Heydari, Kartoosh;
Ripoche, Jean;
Weissman, Jonathan;
Rubinsztein, David C.;
Schekman, Randy;
Malhotra, Vivek;
Moreau, Kevin;
Villeneuve, Julien

Publication type:

Article

CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma.

Published in:

Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-020-01995-4

By:

Liu, S. John;
Malatesta, Martina;
Lien, Brian V.;
Saha, Parna;
Thombare, Shivani S.;
Hong, Sung Jun;
Pedraza, Leslie;
Koontz, Mark;
Seo, Kyounghee;
Horlbeck, Max A.;
He, Daniel;
Birk, Harjus S.;
Jain, Miten;
Olsen, Hugh E.;
Akeson, Mark;
Weissman, Jonathan S.;
Monje, Michelle;
Gupta, Nalin;
Raleigh, David R.;
Ullian, Erik M.

Publication type:

Article

Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.31098

By:

Martinko, Alexander J.;
Truillet, Charles;
Julien, Olivier;
Diaz, Juan E.;
Horlbeck, Max A.;
Whiteley, Gordon;
Blonder, Josip;
Weissman, Jonathan S.;
Bandyopadhyay, Sourav;
Evans, Michael J.;
Wells, James A.

Publication type:

Article

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.19760

By:

Horlbeck, Max A.;
Gilbert, Luke A.;
Villalta, Jacqueline E.;
Adamson, Britt;
Pak, Ryan A.;
Yuwen Chen;
Fields, Alexander P.;
Chong Yon Park;
Corn, Jacob E.;
Kampmann, Martin;
Weissman, Jonathan S.

Publication type:

Article

Nucleosomes impede Cas9 access to DNA in vivo and in vitro.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.12677

By:

Horlbeck, Max A.;
Witkowsky, Lea B.;
Guglielmi, Benjamin;
Replogle, Joseph M.;
Gilbert, Luke A.;
Villalta, Jacqueline E.;
Torigoe, Sharon E.;
Tjian, Robert;
Weissman, Jonathan S.

Publication type:

Article