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HIF-1a induces cell cycle arrest by functionally counteracting Myc.
- Published in:
- EMBO Journal, 2004, v. 23, n. 9, p. 1949, doi. 10.1038/sj.emboj.7600196
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- Publication type:
- Article
p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes.
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- Journal of Clinical Investigation, 2013, v. 123, n. 12, p. 5247, doi. 10.1172/JCI70355
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- Publication type:
- Article
Increased MicroRNA-34b and -34c Predominantly Expressed in Stromal Tissues Is Associated with Poor Prognosis in Human Colon Cancer.
- Published in:
- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0124899
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- Publication type:
- Article
Macrophages, Nitric Oxide and microRNAs Are Associated with DNA Damage Response Pathway and Senescence in Inflammatory Bowel Disease.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044156
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- Publication type:
- Article
Targeted Disruption of Ing2 Results in Defective Spermatogenesis and Development of Soft-Tissue Sarcomas.
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- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015541
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- Publication type:
- Article
Upregulation of the gene encoding a cytoplasmic dynein intermediate chain in senescent human cells.
- Published in:
- Journal of Cellular Biochemistry, 2001, v. 82, n. 3, p. 415, doi. 10.1002/jcb.1169
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- Article
cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome.
- Published in:
- 2001
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- Publication type:
- journal article
Identification of a ≦600-kb region on human chromosome 1q42.3 inducing cellular senescence.
- Published in:
- Oncogene, 2003, v. 22, n. 2, p. 281, doi. 10.1038/sj.onc.1206143
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- Publication type:
- Article
Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system.
- Published in:
- Oncogene, 2002, v. 21, n. 52, p. 7991, doi. 10.1038/sj.onc.1205965
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- Publication type:
- Article
The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions.
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- Oncogene, 2002, v. 21, n. 5, p. 769, doi. 10.1038/sj.onc.1205122
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- Publication type:
- Article
The Multiple Facets of ATRX Protein.
- Published in:
- Cancers, 2021, v. 13, n. 9, p. 2211, doi. 10.3390/cancers13092211
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- Publication type:
- Article
Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1–AKT–p53 Interactions.
- Published in:
- Cancers, 2021, v. 13, n. 9, p. 2195, doi. 10.3390/cancers13092195
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- Publication type:
- Article
Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets.
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- Cancers, 2021, v. 13, n. 8, p. 1853, doi. 10.3390/cancers13081853
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- Publication type:
- Article
Cancer and Aging: Two Tightly Interconnected Biological Processes.
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- Cancers, 2021, v. 13, n. 6, p. 1400, doi. 10.3390/cancers13061400
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- Publication type:
- Article
Telomerase Regulation: A Role for Epigenetics.
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- Cancers, 2021, v. 13, n. 6, p. 1213, doi. 10.3390/cancers13061213
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- Publication type:
- Article
The Δ133p53 Isoforms, Tuners of the p53 Pathway.
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- Cancers, 2020, v. 12, n. 11, p. 3422, doi. 10.3390/cancers12113422
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- Publication type:
- Article
Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence.
- Published in:
- Nature Cell Biology, 2010, v. 12, n. 12, p. 1205, doi. 10.1038/ncb2123
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- Publication type:
- Article
p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence.
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- Nature Cell Biology, 2009, v. 11, n. 9, p. 1135, doi. 10.1038/ncb1928
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- Publication type:
- Article
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks.
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- Nature Cell Biology, 2004, v. 6, n. 2, p. 168, doi. 10.1038/ncb1095
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- Publication type:
- Article
Functional evidence for a telomerase repressor gene on human chromosome 10p15.1.
- Published in:
- Oncogene, 2001, v. 20, n. 7, p. 828, doi. 10.1038/sj.onc.1204165
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- Publication type:
- Article
Radiation-induced astrocyte senescence is rescued by Δ133p53.
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- Neuro-Oncology, 2019, v. 21, n. 4, p. 474, doi. 10.1093/neuonc/noz001
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- Publication type:
- Article
EML4-ALK induces cellular senescence in mortal normal human cells and promotes anchorage-independent growth in hTERT-transduced normal human cells.
- Published in:
- 2021
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- Publication type:
- journal article
Subchromosomal Mapping of a Putative Transformation Suppressor Gene on Human Chromosome 1.
- Published in:
- Cancer Science, 1995, v. 86, n. 5, p. 444, doi. 10.1111/j.1349-7006.1995.tb03077.x
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- Publication type:
- Article
Normal Human Chromosome 1 Carries Suppressor Activity for Various Phenotypes of a Kirsten Murine Sarcoma Virus-transformed NIH/3T3 Cell Line.
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- Cancer Science, 1990, v. 81, n. 11, p. 1095, doi. 10.1111/j.1349-7006.1990.tb02519.x
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- Publication type:
- Article
Targeting cellular senescence in cancer and aging: roles of p53 and its isoforms.
- Published in:
- Carcinogenesis, 2020, v. 41, n. 8, p. 1017, doi. 10.1093/carcin/bgaa071
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- Publication type:
- Article
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
- Published in:
- International Journal of Cancer, 2005, v. 115, n. 4, p. 653, doi. 10.1002/ijc.20879
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- Publication type:
- Article
Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.
- Published in:
- Nature Communications, 2014, v. 5, n. 8, p. 4706, doi. 10.1038/ncomms5706
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- Publication type:
- Article
Cellular Senescence: Mechanisms, Morphology, and Mouse Models.
- Published in:
- Veterinary Pathology, 2020, v. 57, n. 6, p. 747, doi. 10.1177/0300985820943841
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- Publication type:
- Article
Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer.
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- Molecular Carcinogenesis, 1999, v. 25, n. 4, p. 249, doi. 10.1002/(SICI)1098-2744(199908)25:4<249::AID-MC3>3.0.CO;2-Z
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- Publication type:
- Article
Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence.
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- Molecular Carcinogenesis, 1998, v. 22, n. 2, p. 65, doi. 10.1002/(SICI)1098-2744(199806)22:2<65::AID-MC1>3.0.CO;2-J
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- Publication type:
- Article
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence.
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- Cell Death & Disease, 2024, v. 15, n. 6, p. 1, doi. 10.1038/s41419-024-06769-5
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- Publication type:
- Article
Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 7, p. 1, doi. 10.1038/s41419-018-0767-7
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- Publication type:
- Article
Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.
- Published in:
- Genes, Chromosomes & Cancer, 1998, v. 23, n. 2, p. 123, doi. 10.1002/(SICI)1098-2264(199810)23:2<123::AID-GCC5>3.0.CO;2-4
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- Publication type:
- Article
Loss of heterozygosity at chromosome segment Xq25-26.1 in advanced human ovarian carcinomas.
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- Genes, Chromosomes & Cancer, 1997, v. 20, n. 3, p. 234, doi. 10.1002/(SICI)1098-2264(199711)20:3<234::AID-GCC3>3.0.CO;2-3
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- Publication type:
- Article
Normal human chromosome 2 induces cellular senescence in the human cervical carcinoma cell line SiHa.
- Published in:
- Genes, Chromosomes & Cancer, 1995, v. 14, n. 2, p. 120, doi. 10.1002/gcc.2870140206
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- Publication type:
- Article
Delayed kinetics of DNA double-strand break processing in normal and pathological aging.
- Published in:
- Aging Cell, 2008, v. 7, n. 1, p. 89, doi. 10.1111/j.1474-9726.2007.00354.x
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- Publication type:
- Article
Frame-shift mutation and reduced transcript of p53 gene in a renal cell carcinoma cell line, RCC23.
- Published in:
- Human Molecular Genetics, 1995, v. 4, n. 4, p. 771
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- Publication type:
- Article
An amino-terminally truncated p53 protein expressed in a human choriocarcinoma cell line, CC1.
- Published in:
- Human Molecular Genetics, 1995, v. 4, n. 2, p. 313
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- Publication type:
- Article