Works by Horak, Ivan D.

Results: 14

Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft.

Published in:

Cancer Immunology, Immunotherapy, 2005, v. 54, n. 4, p. 315, doi. 10.1007/s00262-004-0597-6

By:

Blumenthal, Rosalyn D.;
Osorio, Lou;
Hayes, Marianne K.;
Horak, Ivan D.;
Hansen, Hans J.;
Goldenberg, David M.

Publication type:

Article

An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression.

Published in:

2017

By:

Schwarz, Luis J;
Hutchinson, Katherine E;
Rexer, Brent N;
Estrada, Mónica Valeria;
Gonzalez Ericsson, Paula I;
Sanders, Melinda E;
Dugger, Teresa C;
Formisano, Luigi;
Guerrero-Zotano, Angel;
Red-Brewer, Monica;
Young, Christian D;
Lantto, Johan;
Pedersen, Mikkel W;
Kragh, Michael;
Horak, Ivan D;
Arteaga, Carlos L

Publication type:

journal article

Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody.

Published in:

Nature Medicine, 2005, v. 11, n. 11, p. 1250, doi. 10.1038/nm1322

By:

Sharkey, Robert M.;
Cardillo, Thomas M.;
Rossi, Edmund A.;
Chien-Hsing Chang;
Karacay, Habibe;
McBride, William J.;
Hansen, Hans J.;
Horak, Ivan D.;
Goldenberg, David M.

Publication type:

Article

Post-therapy serum prostate-specific antigen level and survival in patients with androgen-independent prostate cancer.

Published in:

1999

By:

Scher, Howard I.;
Kelly, W. M. Kevin;
Zhang, Zuo-Feng;
Ouyang, Peter;
Sun, Min;
Schwartz, Morton;
Ding, Cliff;
Wang, Weiping;
Horak, Ivan D.;
Kremer, Alton B.;
Scher, H I;
Kelly, W M;
Zhang, Z F;
Ouyang, P;
Sun, M;
Schwartz, M;
Ding, C;
Wang, W;
Horak, I D;
Kremer, A B

Publication type:

journal article

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype.

Published in:

Science Translational Medicine, 2020, v. 12, n. 555, p. 1, doi. 10.1126/scitranslmed.aax8313

By:

Lupo, Barbara;
Sassi, Francesco;
Pinnelli, Marika;
Galimi, Francesco;
Zanella, Eugenia R.;
Vurchio, Valentina;
Migliardi, Giorgia;
Gagliardi, Paolo Armando;
Puliafito, Alberto;
Manganaro, Daria;
Luraghi, Paolo;
Kragh, Michael;
Pedersen, Mikkel W.;
Horak, Ivan D.;
Boccaccio, Carla;
Medico, Enzo;
Primo, Luca;
Nichol, Daniel;
Spiteri, Inmaculada;
Heide, Timon

Publication type:

Article

Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform.

Published in:

2019

By:

Gjetting, Torben;
Gad, Monika;
Fröhlich, Camilla;
Lindsted, Trine;
Melander, Maria C;
Bhatia, Vikram K;
Grandal, Michael M;
Dietrich, Nikolaj;
Uhlenbrock, Franziska;
Galler, Gunther R;
Strandh, Magnus;
Lantto, Johan;
Bouquin, Thomas;
Horak, Ivan D;
Kragh, Michael;
Pedersen, Mikkel W;
Koefoed, Klaus

Publication type:

Report

Clinical-Scale Radiolabeling of a Humanized Anticarcinoembryonic Antigen Monoclonal Antibody, hMN-14, with Residualizing <sup>131</sup>I for Use in Radioimmunotherapy.

Published in:

Journal of Nuclear Medicine, 2005, v. 46, n. 1, p. 153

By:

Govindan, Serengulam V.;
Griffiths, Gary L.;
Stein, Rhona;
Andrews, Philip;
Sharkey, Robert M.;
Hansen, Hans J.;
Horak, Ivan D.;
Goldenberg, David M.

Publication type:

Article

Reagents and Methods for PET Using Bispecific Antibody Pretargeting and <sup>68</sup>Ga-Radiolabeled Bivalent Hapten-Peptide-Chelate Conjugates.

Published in:

Journal of Nuclear Medicine, 2004, v. 45, n. 1, p. 30

By:

Griffiths, Gary L.;
Chien-Hsing Chang;
McBride, William J.;
Rossi, Edmund A.;
Sheerin, Agatha;
Tejada, German R.;
Karacay, Habibe;
Sharkey, Robert M.;
Horak, Ivan D.;
Hansen, Hans J.;
Goldenberg, David M.

Publication type:

Article

Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models.

Published in:

Journal of Neuro-Oncology, 2018, v. 138, n. 3, p. 489, doi. 10.1007/s11060-018-2832-6

By:

Keir, Stephen T.;
Chandramohan, Vidyalakshmi;
Hemphill, Carlee D.;
Grandal, Michael M.;
Melander, Maria Carlsen;
Pedersen, Mikkel W.;
Horak, Ivan D.;
Kragh, Michael;
Desjardins, Annick;
Friedman, Henry S.;
Bigner, Darell D.

Publication type:

Article

Effects of the tyrosine-kinase inhibitor geldanamycin on ligand-induced HER-2/NEU activation, receptor expression and proliferation of HER-2-positive malignant cell lines.

Published in:

International Journal of Cancer, 1997, v. 70, n. 2, p. 221, doi. 10.1002/(SICI)1097-0215(19970117)70:2<221::AID-IJC14>3.0.CO;2-L

By:

Hartmann, Frank;
Horak, Eva M.;
Cho, Cheryl;
Lupu, Ruth;
Bolen, Joseph B.;
Stetler-Stevenson, Mary A.;
Pfreundschuh, Michael;
Waldmann, Thomas A.;
Horak, Ivan D.

Publication type:

Article

Forty‐nine gastric cancer cell lines with integrative genomic profiling for development of c‐<italic>MET</italic> inhibitor.

Published in:

International Journal of Cancer, 2018, v. 143, n. 1, p. 151, doi. 10.1002/ijc.31304

By:

Kim, Hyun Jeong;
Kang, Sun Kyoung;
Kwon, Woo Sun;
Kim, Tae Soo;
Jeong, Inhye;
Jeung, Hei‐Cheul;
Kragh, Michael;
Horak, Ivan D.;
Chung, Hyun Cheol;
Rha, Sun Young

Publication type:

Article

Pan-HER-An antibody mixture targeting EGFR, HER2 and HER3 abrogates preformed and ligand-induced EGFR homo- and heterodimers.

Published in:

International Journal of Cancer, 2016, v. 139, n. 9, p. 2095, doi. 10.1002/ijc.30242

By:

Ellebæk, Sofie;
Brix, Susanne;
Grandal, Michael;
Lantto, Johan;
Horak, Ivan D.;
Kragh, Michael;
Poulsen, Thomas Tuxen

Publication type:

Article

Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs.

Published in:

2020

By:

Reddy, Tejaswini P.;
Choi, Dong S.;
Anselme, Ann C.;
Qian, Wei;
Chen, Wen;
Lantto, Johan;
Horak, Ivan D.;
Kragh, Michael;
Chang, Jenny C.;
Rosato, Roberto R.

Publication type:

journal article

First-in-human trial exploring safety, antitumor activity, and pharmacokinetics of Sym013, a recombinant pan-HER antibody mixture, in advanced epithelial malignancies.

Published in:

Investigational New Drugs, 2022, v. 40, n. 3, p. 586, doi. 10.1007/s10637-022-01217-7

By:

Berlin, Jordan;
Tolcher, Anthony W.;
Ding, Cliff;
Whisenant, Jennifer G.;
Horak, Ivan D.;
Wood, Debra L.;
Nadler, Paul I.;
Hansen, Ulla Holm;
Lantto, Johan;
Skartved, Niels Jørgen Ø.;
Pedersen, Mikkel W.;
Patnaik, Amita

Publication type:

Article