Works by Hoppe, Thorsten

Results: 38

Ubiquitin sets the timer: impacts on aging and longevity.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 290, doi. 10.1038/nsmb.2806

By:

Kevei, Éva;
Hoppe, Thorsten

Publication type:

Article

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 12, p. 1345, doi. 10.1038/nsmb.2188

By:

Acs, Klara;
Luijsterburg, Martijn S;
Ackermann, Leena;
Salomons, Florian A;
Hoppe, Thorsten;
Dantuma, Nico P

Publication type:

Article

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage.

Published in:

Cell Death & Disease, 2020, v. 11, n. 9, p. 1, doi. 10.1038/s41419-020-02923-x

By:

Albert, Marie-Christine;
Brinkmann, Kerstin;
Pokrzywa, Wojciech;
Günther, Saskia Diana;
Krönke, Martin;
Hoppe, Thorsten;
Kashkar, Hamid

Publication type:

Article

Reprograming of proteasomal degradation by branched chain amino acid metabolism.

Published in:

Aging Cell, 2022, v. 21, n. 12, p. 1, doi. 10.1111/acel.13725

By:

Ravanelli, Sonia;
Li, Qiaochu;
Annibal, Andrea;
Trifunovic, Aleksandra;
Antebi, Adam;
Hoppe, Thorsten

Publication type:

Article

The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans.

Published in:

Journal of Cell Biology, 2007, v. 177, n. 2, p. 205, doi. 10.1083/jcb.200607084

By:

Landsverk, Megan L.;
Li, Shumin;
Hutagalung, Alex H.;
Najafov, Ayaz;
Hoppe, Thorsten;
Barral, José M.;
Epstein, Henry F.

Publication type:

Article

MicroRNAs meet calcium: Joint venture in ER proteostasis.

Published in:

Science Signaling, 2014, v. 7, n. 350, p. 1, doi. 10.1126/scisignal.2005671

By:

Finger, Fabian;
Hoppe, Thorsten

Publication type:

Article

Author Correction: A heterotypic assembly mechanism regulates CHIP E3 ligase activity.

Published in:

2024

By:

Das, Aniruddha;
Thapa, Pankaj;
Santiago, Ulises;
Shanmugam, Nilesh;
Banasiak, Katarzyna;
Dązbrowska, Katarzyna;
Nolte, Hendrik;
Szulc, Natalia A;
Gathungu, Rose M;
Cysewski, Dominik;
Krüeger, Marcus;
Dadlez, Michał;
Nowotny, Marcin;
Camacho, Carlos J;
Hoppe, Thorsten;
Pokrzywa, Wojciech

Publication type:

Correction Notice

A heterotypic assembly mechanism regulates CHIP E3 ligase activity.

Published in:

EMBO Journal, 2022, v. 41, n. 15, p. 1, doi. 10.15252/embj.2021109566

By:

Das, Aniruddha;
Thapa, Pankaj;
Santiago, Ulises;
Shanmugam, Nilesh;
Banasiak, Katarzyna;
Dąbrowska, Katarzyna;
Nolte, Hendrik;
Szulc, Natalia A;
Gathungu, Rose M;
Cysewski, Dominik;
Krüger, Marcus;
Dadlez, Michał;
Nowotny, Marcin;
Camacho, Carlos J;
Hoppe, Thorsten;
Pokrzywa, Wojciech

Publication type:

Article

Hepatic ERAD takes control of the organism.

Published in:

EMBO Journal, 2018, v. 37, n. 22, p. N.PAG, doi. 10.15252/embj.2018100676

By:

Dreher, Lena‐Sophie;
Hoppe, Thorsten

Publication type:

Article

Ring of Change: CDC48/p97 Drives Protein Dynamics at Chromatin.

Published in:

Frontiers in Genetics, 2016, p. 1, doi. 10.3389/fgene.2016.00073

By:

Franz, André;
Ackermann, Leena;
Hoppe, Thorsten;
Mehdipour, Parvin;
Jentsch, Stefan

Publication type:

Article

Regulation of the DNA damage response by ubiquitin conjugation.

Published in:

Frontiers in Genetics, 2015, v. 6, p. 1, doi. 10.3389/fgene.2015.00098

By:

Brinkmann, Kerstin;
Schell, Michael;
Hoppe, Thorsten;
Kashkar, Hamid

Publication type:

Article

Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33467-7

By:

Segref, Alexandra;
Vakkayil, Kavya L.;
Padvitski, Tsimafei;
Li, Qiaochu;
Kroef, Virginia;
Lormann, Jakob;
Körner, Lioba;
Finger, Fabian;
Hoppe, Thorsten

Publication type:

Article

Membrane localization of LGG-1/GABARAP is dispensable for autophagy in C. elegans.

Published in:

Autophagy, 2023, v. 19, n. 12, p. 3254, doi. 10.1080/15548627.2023.2249393

By:

Leboutet, Romane;
Largeau, Céline;
Culetto, Emmanuel;
Lefebvre, Christophe;
Hoppe, Thorsten;
Legouis, Renaud

Publication type:

Article

Organismal Protein Homeostasis Mechanisms.

Published in:

Genetics, 2020, v. 215, n. 4, p. 889, doi. 10.1534/genetics.120.301283

By:

Hoppe, Thorsten;
Cohen, Ehud

Publication type:

Article

A Novel Interaction Between Aging and ER Overload in a Protein Conformational Dementia.

Published in:

Genetics, 2013, v. 193, n. 3, p. 865, doi. 10.1534/genetics.112.149088

By:

Schipanski, Angela;
Lange, Sascha;
Segref, Alexandra;
Gutschmidt, Aljona;
Lomas, David A.;
Miranda, Elena;
Schweizer, Michaela;
Hoppe, Thorsten;
Glatzel, Markus

Publication type:

Article

A Screenable in vivo Assay to Study Proteostasis Networks in Caenorhabditis elegans.

Published in:

Genetics, 2011, v. 187, n. 4, p. 1235, doi. 10.1534/genetics.111.126797

By:

Segref, Alexandra;
Torres, Serena;
Hoppe, Thorsten

Publication type:

Article

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05320-3

By:

Koyuncu, Seda;
Saez, Isabel;
Lee, Hyun Ju;
Gutierrez-Garcia, Ricardo;
Pokrzywa, Wojciech;
Fatima, Azra;
Hoppe, Thorsten;
Vilchez, David

Publication type:

Article

Maintaining proteostasis under mechanical stress.

Published in:

EMBO Reports, 2021, v. 22, n. 8, p. 1, doi. 10.15252/embr.202152507

By:

Höhfeld, Jörg;
Benzing, Thomas;
Bloch, Wilhelm;
Fürst, Dieter O;
Gehlert, Sebastian;
Hesse, Michael;
Hoffmann, Bernd;
Hoppe, Thorsten;
Huesgen, Pitter F;
Köhn, Maja;
Kolanus, Waldemar;
Merkel, Rudolf;
Niessen, Carien M;
Pokrzywa, Wojciech;
Rinschen, Markus M;
Wachten, Dagmar;
Warscheid, Bettina

Publication type:

Article

Think locally: control of ubiquitin-dependent protein degradation in neurons.

Published in:

EMBO Reports, 2009, v. 10, n. 1, p. 44, doi. 10.1038/embor.2008.229

By:

Segref, Alexandra;
Hoppe, Thorsten

Publication type:

Article

A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 22, p. 3407, doi. 10.1093/hmg/ddi371

By:

Springer, Wolfdieter;
Hoppe, Thorsten;
Schmidt, Enrico;
Baumeister, Ralf

Publication type:

Article

Ubiquitylation Pathways In Insulin Signaling and Organismal Homeostasis.

Published in:

BioEssays, 2018, v. 40, n. 5, p. 1, doi. 10.1002/bies.201700223

By:

Balaji, Vishnu;
Pokrzywa, Wojciech;
Hoppe, Thorsten

Publication type:

Article

Repair or destruction-an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis.

Published in:

FEBS Letters, 2017, v. 591, n. 17, p. 2616, doi. 10.1002/1873-3468.12750

By:

Kevei, Éva;
Pokrzywa, Wojciech;
Hoppe, Thorsten

Publication type:

Article

LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85748

By:

Leboutet, Romane;
Largeau, Céline;
Müller, Leonie;
Prigent, Magali;
Quinet, Grégoire;
Rodriguez, Manuel S.;
Cuif, Marie-Hélène;
Hoppe, Thorsten;
Culetto, Emmanuel;
Lefebvre, Christophe;
Legouis, Renaud

Publication type:

Article

Erratum: Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.

Published in:

Nature Communications, 2016, v. 7, n. 5, p. 11593, doi. 10.1038/ncomms11593

By:

Franz, André;
Pirson, Paul A.;
Pilger, Domenic;
Halder, Swagata;
Achuthankutty, Divya;
Kashkar, Hamid;
Ramadan, Kristijan;
Hoppe, Thorsten

Publication type:

Article

Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.

Published in:

Nature Communications, 2016, v. 7, n. 2, p. 10612, doi. 10.1038/ncomms10612

By:

Franz, André;
Pirson, Paul A.;
Pilger, Domenic;
Halder, Swagata;
Achuthankutty, Divya;
Kashkar, Hamid;
Ramadan, Kristijan;
Hoppe, Thorsten

Publication type:

Article

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 11, p. 693, doi. 10.1038/nchembio.1352

By:

Schmeisser, Kathrin;
Mansfeld, Johannes;
Kuhlow, Doreen;
Weimer, Sandra;
Priebe, Steffen;
Heiland, Ines;
Birringer, Marc;
Groth, Marco;
Segref, Alexandra;
Kanfi, Yariv;
Price, Nathan L;
Schmeisser, Sebastian;
Schuster, Stefan;
Pfeiffer, Andreas F H;
Guthke, Reinhard;
Platzer, Matthias;
Hoppe, Thorsten;
Cohen, Haim Y;
Zarse, Kim;
Sinclair, David A

Publication type:

Article

Temperature-Dependent Regulation of Proteostasis and Longevity.

Published in:

Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.853588

By:

Vakkayil, Kavya Leo;
Hoppe, Thorsten

Publication type:

Article

Author Correction: The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.

Published in:

2020

By:

Koyuncu, Seda;
Saez, Isabel;
Lee, Hyun Ju;
Gutierrez-Garcia, Ricardo;
Pokrzywa, Wojciech;
Fatima, Azra;
Hoppe, Thorsten;
Vilchez, David

Publication type:

Correction Notice

The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13540-4

By:

Kumsta, Caroline;
Chang, Jessica T.;
Lee, Reina;
Tan, Ee Phie;
Yang, Yongzhi;
Loureiro, Rute;
Choy, Elizabeth H.;
Lim, Shaun H. Y.;
Saez, Isabel;
Springhorn, Alexander;
Hoppe, Thorsten;
Vilchez, David;
Hansen, Malene

Publication type:

Article

The ubiquitin-selective chaperone CDC-48/p97, a new player in DNA replication.

Published in:

Cell Cycle, 2009, v. 8, n. 2, p. 185, doi. 10.4161/cc.8.2.7356

By:

Deichsel, Alexandra;
Mouysset, Julien;
Hoppe, Thorsten

Publication type:

Article

DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.

Published in:

Nature, 2013, v. 501, n. 7467, p. 416, doi. 10.1038/nature12452

By:

Ermolaeva, Maria A.;
Segref, Alexandra;
Dakhovnik, Alexander;
Ou, Hui-Ling;
Schneider, Jennifer I.;
Utermöhlen, Olaf;
Hoppe, Thorsten;
Schumacher, Björn

Publication type:

Article

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0984-3

By:

Fatima, Azra;
Irmak, Dilber;
Noormohammadi, Alireza;
Rinschen, Markus M.;
Das, Aniruddha;
Leidecker, Orsolya;
Schindler, Christina;
Sánchez-Gaya, Víctor;
Wagle, Prerana;
Pokrzywa, Wojciech;
Hoppe, Thorsten;
Rada-Iglesias, Alvaro;
Vilchez, David

Publication type:

Article

The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy.

Published in:

Aging Cell, 2020, v. 19, n. 1, p. N.PAG, doi. 10.1111/acel.13051

By:

Herzog, Laura K.;
Kevei, Éva;
Marchante, Ricardo;
Böttcher, Claudia;
Bindesbøll, Christian;
Lystad, Alf Håkon;
Pfeiffer, Annika;
Gierisch, Maria E.;
Salomons, Florian A.;
Simonsen, Anne;
Hoppe, Thorsten;
Dantuma, Nico P.

Publication type:

Article

Ubiquitin-dependent regulation of a conserved DMRT protein controls sexually dimorphic synaptic connectivity and behavior.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.59614

By:

Bayer, Emily A.;
Stecky, Rebecca C.;
Neal, Lauren;
Katsamba, Phinikoula S.;
Ahlsen, Goran;
Balaji, Vishnu;
Hoppe, Thorsten;
Shapiro, Lawrence;
Oren-Suissa, Meital;
Hobert, Oliver

Publication type:

Article

The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis.

Published in:

Nature Cell Biology, 2011, v. 13, n. 3, p. 273, doi. 10.1038/ncb2200

By:

Kuhlbrodt, Kirsten;
Janiesch, Philipp Christoph;
Kevei, Éva;
Segref, Alexandra;
Barikbin, Roja;
Hoppe, Thorsten

Publication type:

Article

The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy.

Published in:

Nature Cell Biology, 2007, v. 9, n. 4, p. 379, doi. 10.1038/ncb1554

By:

Janiesch, Philipp Christoph;
Kim, Johnny;
Mouysset, Julien;
Barikbin, Roja;
Lochmüller, Hanns;
Cassata, Giuseppe;
Krause, Sabine;
Hoppe, Thorsten

Publication type:

Article

The ubiquitin-selective chaperone Cdc48/p97 associates with Ubx3 to modulate monoubiquitylation of histone H2B.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 17, p. 10975, doi. 10.1093/nar/gku786

By:

Bonizec, Mélanie;
Hérissant, Lucas;
Pokrzywa, Wojciech;
Geng, Fuqiang;
Wenzel, Sabine;
Howard, Gregory C.;
Rodriguez, Paco;
Krause, Sabine;
Tansey, William P.;
Hoppe, Thorsten;
Dargemont, Catherine

Publication type:

Article

Stefan Jentsch (1955-2016)-Maestro of the ubiquitin family.

Published in:

EMBO Journal, 2017, v. 36, n. 1, p. 1, doi. 10.15252/embj.201696176

By:

Hoppe, Thorsten;
Branzei, Dana

Publication type:

Article