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Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation.
- Published in:
- Biochemical Society Transactions, 2024, v. 52, n. 1, p. 431, doi. 10.1042/BST20230918
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- Publication type:
- Article
Induced pluripotent stem cell model revealed impaired neurovascular interaction in genetic small vessel disease Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy.
- Published in:
- Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1195470
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- Publication type:
- Article
Proteolysis of the low‐density lipoprotein receptor in hepatocytes is mediated by BMP1 but not by other astacin proteases.
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- FEBS Letters, 2023, v. 597, n. 11, p. 1489, doi. 10.1002/1873-3468.14667
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- Publication type:
- Article
Severe and Regionally Widespread Increases in Tissue Urea in the Human Brain Represent a Novel Finding of Pathogenic Potential in Parkinson's Disease Dementia.
- Published in:
- Frontiers in Molecular Neuroscience, 2021, v. 14, p. 1, doi. 10.3389/fnmol.2021.711396
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- Publication type:
- Article
Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson's Disease Dementia.
- Published in:
- Metabolites (2218-1989), 2021, v. 11, n. 9, p. 569, doi. 10.3390/metabo11090569
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- Publication type:
- Article
Widespread Decreases in Cerebral Copper Are Common to Parkinson's Disease Dementia and Alzheimer's Disease Dementia.
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- Frontiers in Aging Neuroscience, 2021, v. 13, p. N.PAG, doi. 10.3389/fnagi.2021.641222
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- Publication type:
- Article
Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat Brain.
- Published in:
- Metabolites (2218-1989), 2020, v. 10, n. 11, p. 438, doi. 10.3390/metabo10110438
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- Publication type:
- Article
Discovery and characterization of ACE2 - a 20-year journey of surprises from vasopeptidase to COVID-19.
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- Clinical Science, 2020, v. 134, n. 18, p. 2499, doi. 10.1042/CS20200476
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- Publication type:
- Article
Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network.
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- Neurochemical Research, 2020, v. 45, n. 7, p. 1711, doi. 10.1007/s11064-020-03019-w
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- Publication type:
- Article
A Preliminary Evaluation of the Pro-Chondrogenic Potential of 3D-Bioprinted Poly(ester Urea) Scaffolds.
- Published in:
- Polymers (20734360), 2020, v. 12, n. 7, p. 1478, doi. 10.3390/polym12071478
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- Publication type:
- Article
Evidence that levels of nine essential metals in post-mortem human-Alzheimer's-brain and ex vivo rat-brain tissues are unaffected by differences in post-mortem delay, age, disease staging, and brain bank location.
- Published in:
- Metallomics, 2020, v. 12, n. 6, p. 952, doi. 10.1039/d0mt00048e
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- Publication type:
- Article
The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43.
- Published in:
- Bioscience Reports, 2020, v. 40, n. 4, p. 1, doi. 10.1042/BSR20200435
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- Publication type:
- Article
Author Correction: Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47814-0
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- Publication type:
- Article
P4‐524: PROTEOLYTIC CLEAVAGE OF TAU IN CORTICOBASAL DEGENERATION AND PROGRESSIVE SUPRANUCLEAR PALSY PATHOGENESIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1514, doi. 10.1016/j.jalz.2019.08.071
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- Publication type:
- Article
Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.
- Published in:
- Journal of Neurochemistry, 2019, v. 149, n. 3, p. 399, doi. 10.1111/jnc.14666
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- Publication type:
- Article
Improving the Gene Ontology Resource to Facilitate More Informative Analysis and Interpretation of Alzheimer's Disease Data.
- Published in:
- Genes, 2018, v. 9, n. 12, p. 593, doi. 10.3390/genes9120593
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- Publication type:
- Article
Modelling Sporadic Alzheimer’s Disease Using Induced Pluripotent Stem Cells.
- Published in:
- Neurochemical Research, 2018, v. 43, n. 12, p. 2179, doi. 10.1007/s11064-018-2663-z
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- Publication type:
- Article
P4‐054: KLOTHO ENHANCES NEURONAL ACTIVITY THROUGH INTERACTION WITH A CELL‐SURFACE RECEPTOR.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1453, doi. 10.1016/j.jalz.2018.06.2457
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- Publication type:
- Article
P3‐230: IDENTIFICATION OF A PLASMA PROTEIN SIGNATURE FOR ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1159, doi. 10.1016/j.jalz.2018.06.1589
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- Publication type:
- Article
P3‐142: SOLUBLE AMYLOID PRECURSOR PROTEIN α (SAPPα) PROMOTES SYNAPTOGENESIS IN HUMAN‐INDUCED PLURIPOTENT STEM CELL‐DERIVED NEURONS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1122, doi. 10.1016/j.jalz.2018.06.1499
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- Publication type:
- Article
P1‐183: THE ROLE OF AMYLIN IN ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P348, doi. 10.1016/j.jalz.2018.06.187
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- Publication type:
- Article
P1‐219: AMYLOID‐β DEGRADATION IN INDUCED PLURIPOTENT STEM CELL (IPSC)‐DERIVED NEURONS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P362, doi. 10.1016/j.jalz.2018.06.224
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- Publication type:
- Article
O1‐06‐06: PROTEOLYTIC CLEAVAGE OF TAU IN DEMENTIA PATHOGENESIS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P232, doi. 10.1016/j.jalz.2018.06.2365
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- Publication type:
- Article
Plasma metals as potential biomarkers in dementia: a case-control study in patients with sporadic Alzheimer's disease.
- Published in:
- BioMetals, 2018, v. 31, n. 2, p. 267, doi. 10.1007/s10534-018-0089-3
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- Publication type:
- Article
Amyloid β synaptotoxicity is Wnt‐PCP dependent and blocked by fasudil.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 3, p. 306, doi. 10.1016/j.jalz.2017.09.008
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- Publication type:
- Article
Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype.
- Published in:
- PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159119
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- Publication type:
- Article
Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: metabolic basis for dementia.
- Published in:
- Scientific Reports, 2016, p. 27524, doi. 10.1038/srep27524
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- Publication type:
- Article
Angiotensin-converting enzyme 2 is subject to post-transcriptional regulation by miR-421.
- Published in:
- Clinical Science, 2014, v. 127, n. 4, p. 243, doi. 10.1042/CS20130420
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- Publication type:
- Article
BIN1 Is Decreased in Sporadic but Not Familial Alzheimer’s Disease or in Aging.
- Published in:
- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078806
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- Publication type:
- Article
Prion Protein Is Decreased in Alzheimer's Brain and Inversely Correlates with BACE1 Activity, Amyloid-β Levels and Braak Stage.
- Published in:
- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0059554
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- Publication type:
- Article
Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031754
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- Publication type:
- Article
A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema.
- Published in:
- Human Mutation, 2011, v. 32, n. 11, p. 1326, doi. 10.1002/humu.21579
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- Publication type:
- Article
Alkaline Phosphatase Is Increased in both Brain and Plasma in Alzheimer's Disease.
- Published in:
- Neurodegenerative Diseases, 2011, v. 9, n. 1, p. 31, doi. 10.1159/000329722
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- Publication type:
- Article
Glypican-1 facilitates prion conversion in lipid rafts.
- Published in:
- Journal of Neurochemistry, 2011, v. 116, n. 5, p. 721, doi. 10.1111/j.1471-4159.2010.06936.x
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- Publication type:
- Article
Prion Protein is Reduced in Aging and in Sporadic but not in Familial Alzheimer's Disease.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 22, n. 3, p. 1023, doi. 10.3233/JAD-2010-101071
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- Publication type:
- Article
The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a β-secretase dependent pathway
- Published in:
- 2010
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- Publication type:
- Abstract
Cellular prion protein regulates processing of the amyloid precursor protein by directly interacting with the pro-domain of BACE1 and altering its cellular localization
- Published in:
- 2010
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- Publication type:
- Abstract
Plasma alkaline phosphatase inversely correlates with cognitive function in Alzheimer's disease
- Published in:
- 2010
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- Publication type:
- Abstract
Ligand-Stimulated VEGFR2 Signaling is Regulated by Co-Ordinated Trafficking and Proteolysis.
- Published in:
- Traffic, 2010, v. 11, n. 1, p. 161, doi. 10.1111/j.1600-0854.2009.01001.x
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- Publication type:
- Article
Glypican-1 Mediates Both Prion Protein Lipid Raft Association and Disease Isoform Formation.
- Published in:
- PLoS Pathogens, 2009, v. 5, n. 11, p. 1, doi. 10.1371/journal.ppat.1000666
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- Publication type:
- Article
Plasma Angiotensin-Converting Enzyme in Alzheimer's Disease.
- Published in:
- Journal of Alzheimer's Disease, 2009, v. 16, n. 3, p. 609, doi. 10.3233/JAD-2009-1002
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- Publication type:
- Article
The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill.
- Published in:
- Journal of the Renin-Angiotensin-Aldosterone System, 2008, v. 9, n. 4, p. 221, doi. 10.1177/1470320308096405
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- Publication type:
- Article
P1-458: Effect of disease-associated mutations in the prion protein on the β-secretase cleavage of the amyloid precursor protein
- Published in:
- 2008
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- Publication type:
- Abstract
P1-482: Prion protein regulates the β-secretase cleavage of the Alzheimer amyloid precursor protein through direct interaction with BACE1
- Published in:
- 2008
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- Publication type:
- Abstract
P2-209: ADAM family–mediated shedding of the cellular prion protein does not affect its conversion into the disease-associated scrapie isoform
- Published in:
- 2008
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- Publication type:
- Abstract
P2-482: De novo design of cellular active beta-secretase inhibitors
- Published in:
- 2008
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- Publication type:
- Abstract
Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain
- Published in:
- FEBS Letters, 2008, v. 582, n. 2, p. 385, doi. 10.1016/j.febslet.2007.11.085
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- Publication type:
- Article
Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease.
- Published in:
- 2007
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- Publication type:
- journal article
GPI-Anchor Dictates Trafficking of Membrane Dipeptidase.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A610, doi. 10.1096/fasebj.21.5.a610-c
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- Publication type:
- Article