Works by Hongbo Chi

Results: 52

iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.

Published in:

2017

By:

Jinhong Wu;
Jialong Yang;
Kai Yang;
Hongxia Wang;
Gorentla, Balachandra;
Jinwook Shin;
Yurong Qiu;
Que, Loretta G.;
Foster, W. Michael;
Zhenwei Xia;
Hongbo Chi;
Xiao-Ping Zhong;
Wu, Jinhong;
Yang, Jialong;
Yang, Kai;
Wang, Hongxia;
Shin, Jinwook;
Qiu, Yurong;
Xia, Zhenwei;
Chi, Hongbo

Publication type:

journal article

Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation.

Published in:

2016

By:

Nguyen, Hung D.;
Chatterjee, Shilpak;
Haarberg, Kelley M. K.;
Yongxia Wu;
Bastian, David;
Heinrichs, Jessica;
Jianing Fu;
Daenthanasanmak, Anusara;
Schutt, Steven;
Shrestha, Sharad;
Chen Liu;
Honglin Wang;
Hongbo Chi;
Mehrotra, Shikhar;
Xue-Zhong Yu;
Wu, Yongxia;
Fu, Jianing;
Liu, Chen;
Wang, Honglin;
Chi, Hongbo

Publication type:

journal article

Loss of Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) Reveals a Requirement for MAPK Signalling in Mouse Sex Determination.

Published in:

PLoS Biology, 2009, v. 7, n. 9, p. 1, doi. 10.1371/journal.pbio.1000196

By:

Bogani, Debora;
Siggers, Pam;
Brixey, Rachel;
Warr, Nick;
Beddow, Sarah;
Edwards, Jessica;
Williams, Debbie;
Wilhelm, Dagmar;
Koopman, Peter;
Flavell, Richard A.;
Hongbo Chi;
Ostrer, Harry;
Wells, Sara;
Cheeseman, Michael;
Greenfield, Andy

Publication type:

Article

The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells.

Published in:

Nature Immunology, 2010, v. 11, n. 11, p. 1047, doi. 10.1038/ni.1939

By:

Liu, Guangwei;
Yang, Kai;
Burns, Samir;
Shrestha, Sharad;
Chi, Hongbo

Publication type:

Article

The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR.

Published in:

Nature Immunology, 2009, v. 10, n. 7, p. 769, doi. 10.1038/ni.1743

By:

Guangwei Liu;
Burns, Samir;
Gonghua Huang;
Boyd, Kelli;
Proia, Richard L.;
Flavell, Richard A.;
Hongbo Chi

Publication type:

Article

COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor–induced entry into the cell cycle from quiescence.

Published in:

Nature Immunology, 2007, v. 8, n. 11, p. 1236, doi. 10.1038/ni1514

By:

Menon, Suchithra;
Chi, Hongbo;
Zhang, Huiyong;
Deng, Xing Wang;
Flavell, Richard A;
Wei, Ning

Publication type:

Article

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

Published in:

Nature Immunology, 2006, v. 7, n. 8, p. 851, doi. 10.1038/ni1355

By:

Wan, Yisong Y.;
Hongbo Chi;
Min Xie;
Schneider, Michael D.;
Flavell, Richard A.

Publication type:

Article

Gfi1.

Published in:

Cell Cycle, 2013, v. 12, n. 23, p. 3581, doi. 10.4161/cc.26824

By:

Zhichang Shi, Lewis;
Hongbo Chi

Publication type:

Article

Immunology: Sensing the enemy within.

Published in:

Nature, 2007, v. 448, n. 7152, p. 423, doi. 10.1038/448423a

By:

Chi, Hongbo;
Flavell, Richard A.

Publication type:

Article

mTOR links environmental signals to T cell fate decisions.

Published in:

Frontiers in Immunology, 2015, v. 5, p. 1, doi. 10.3389/fimmu.2014.00686

By:

Chapman, Nicole M.;
Hongbo Chi;
Powell, Jonathan;
Matarese, Giuseppe

Publication type:

Article

Parameters and Morphological Changes of Erythrocytes and Platelets of COVID-19 Subjects: A Longitudinal Cohort Study.

Published in:

Infection & Drug Resistance, 2023, v. 16, p. 1657, doi. 10.2147/IDR.S400735

By:

Shen, Liping;
Chen, Linping;
Chi, Hongbo;
Luo, Lifei;
Ruan, Jinsu;
Zhao, Xinzhuan;
Jiang, Yi;
Tung, Tao-Hsin;
Zhu, Hongguo;
Zhou, Kai;
Shen, Bo;
Xu, Jiaqin

Publication type:

Article

The hemocyte counts as a potential biomarker for predicting disease progression in COVID-19: a retrospective study.

Published in:

Clinical Chemistry & Laboratory Medicine, 2020, v. 58, n. 7, p. 1106, doi. 10.1515/cclm-2020-0377

By:

Zheng, Yufen;
Zhang, Ying;
Chi, Hongbo;
Chen, Shiyong;
Peng, Minfei;
Luo, Lifei;
Chen, Linping;
Li, Jun;
Shen, Bo;
Wang, Donglian

Publication type:

Article

Sin1–mTORC2 signaling drives glycolysis of developing thymocytes.

Published in:

Journal of Molecular Cell Biology, 2019, v. 11, n. 2, p. 91, doi. 10.1093/jmcb/mjy078

By:

Chi, Hongbo

Publication type:

Article

Structure-Based Stepwise Screening of PPARγ Antagonists as Potential Competitors with NCOA1 Coactivator Peptide for PPARγ CIS Site.

Published in:

International Journal of Peptide Research & Therapeutics, 2019, v. 25, n. 4, p. 1369, doi. 10.1007/s10989-018-9782-x

By:

Shen, Yi;
Chi, Hongbo;
Zhou, Jinhu;
Luo, Lifei;
Tu, Qian;
Qi, Cancan;
Gao, Zuhua

Publication type:

Article

iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.

Published in:

2018

By:

Wu, Jinhong;
Yang, Jialong;
Yang, Kai;
Wang, Hongxia;
Gorentla, Balachandra;
Shin, Jinwook;
Qiu, Yurong;
Que, Loretta G;
Foster, W Michael;
Xia, Zhenwei;
Chi, Hongbo;
Zhong, Xiao-Ping

Publication type:

journal article

iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 4, p. 1685, doi. 10.1172/JCI69780

By:

Jinhong Wu;
Jialong Yang;
Kai Yang;
Hongxia Wang;
Gorentla, Balachandra;
Jinwook Shin;
Yurong Qiu;
Que, Loretta G.;
Foster, W. Michael;
Zhenwei Xia;
Hongbo Chi;
Xiao-Ping Zhong

Publication type:

Article

Tuning mTOR activity for immune balance.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 12, p. 5001, doi. 10.1172/JCI73202

By:

Kai Yang;
Hongbo Chi

Publication type:

Article

Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis.

Published in:

2006

By:

He, Yun;
Luo, Yan;
Tang, Shibo;
Rajantie, Iiro;
Salven, Petri;
Heil, Matthias;
Zhang, Rong;
Luo, Dianhong;
Li, Xianghong;
Chi, Hongbo;
Yu, Jun;
Carmeliet, Peter;
Schaper, Wolfgang;
Sinusas, Albert J;
Sessa, William C;
Alitalo, Kari;
Min, Wang

Publication type:

journal article

Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 9, p. 2344, doi. 10.1172/JCI28123

By:

Yun He;
Yan Luo;
Shibo Tang;
Iiro Rajantie;
Petri Salven;
Matthias Heil;
Rong Zhang;
Dianhong Luo;
Xianghong Li;
Hongbo Chi;
Jun Yu;
Carmeliet, Peter;
Wolfgang Schaper;
Sinusas, Albert J.;
Sessa, William C.;
Kari Alitalo;
Wang Min

Publication type:

Article

Vps34-orchestrated lipid signaling processes regulate the transitional heterogeneity and functional adaptation of effector regulatory T cells.

Published in:

PLoS Biology, 2025, v. 23, n. 4, p. 1, doi. 10.1371/journal.pbio.3003074

By:

Norton, Erienne G.;
Chapman, Nicole M.;
Shi, Hao;
Meng, Xiaoxi;
Huang, Hongling;
KC, Anil;
Rankin, Sherri;
Saravia, Jordy;
Yuan, Sujing;
Hu, Haoran;
Vogel, Peter;
Chi, Hongbo

Publication type:

Article

Regulation and function of mTOR signalling in T cell fate decisions.

Published in:

Nature Reviews Immunology, 2012, v. 12, n. 5, p. 325, doi. 10.1038/nri3198

By:

Chi, Hongbo

Publication type:

Article

Physical condition, psychological status, and posttraumatic stress disorder among recovered COVID-19 subjects: A mediation analysis.

Published in:

Frontiers in Psychiatry, 2022, v. 13, p. 1, doi. 10.3389/fpsyt.2022.918679

By:

Kai Zhou;
Hongbo Chi;
Jing Wang;
Yufen Zheng;
Juan Pan;
Die Yu;
Jiaqin Xu;
Hongguo Zhu;
Jun Li;
Shiyong Chen;
Xinzhuan Zhao;
Xiaomai Wu;
Bo Shen;
Tao-Hsin Tung;
Chengwen Luo

Publication type:

Article

Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells.

Published in:

Cardiovascular Research, 2021, v. 117, n. 5, p. 1309, doi. 10.1093/cvr/cvaa208

By:

Amersfoort, Jacob;
Schaftenaar, Frank H;
Douna, Hidde;
Santbrink, Peter J van;
Puijvelde, Gijs H M van;
Slütter, Bram;
Foks, Amanda C;
Harms, Amy;
Moreno-Gordaliza, Estefania;
Wang, Yanyan;
Hankemeier, Thomas;
Bot, Ilze;
Chi, Hongbo;
Kuiper, Johan

Publication type:

Article

Role of mtDNA Haplogroups in the Prevalence of Knee Osteoarthritis in a Southern Chinese Population.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 2, p. 2646, doi. 10.3390/ijms15022646

By:

Hezhi Fang;
Xinwei Liu;
Lijun Shen;
Fengjie Li;
Yihong Liu;
Hongbo Chi;
Huikai Miao;
Jianxin Lu;
Yidong Bai

Publication type:

Article

NetBID2 provides comprehensive hidden driver analysis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38335-6

By:

Dong, Xinran;
Ding, Liang;
Thrasher, Andrew;
Wang, Xinge;
Liu, Jingjing;
Pan, Qingfei;
Rash, Jordan;
Dhungana, Yogesh;
Yang, Xu;
Risch, Isabel;
Li, Yuxin;
Yan, Lei;
Rusch, Michael;
McLeod, Clay;
Yan, Koon-Kiu;
Peng, Junmin;
Chi, Hongbo;
Zhang, Jinghui;
Yu, Jiyang

Publication type:

Article

mTOR signaling and transcriptional regulation in T lymphocytes.

Published in:

Transcription (2154-1264), 2014, v. 5, p. 1

By:

Hu Zeng;
Hongbo Chi

Publication type:

Article

Somatic Mutation and Germline Variants of MINPP1, a Phosphatase Gene Located in Proximity to PTEN on 10q23.3, in Follicular Thyroid Carcinomas.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 4, p. 1801, doi. 10.1210/jcem.86.4.7419

By:

GIMM, OLIVER;
CHI, HONGBO;
DAHIA, PATRICIA L. M.;
PERREN, AUREL;
HINZE, RAOUL;
KOMMINOTH, PAUL;
DRALLE, HENNING;
REYNOLDS, PAUL R.;
ENG, CHARIS

Publication type:

Article

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

Published in:

Nature Immunology, 2015, v. 16, n. 2, p. 178, doi. 10.1038/ni.3076

By:

Shrestha, Sharad;
Yang, Kai;
Guy, Cliff;
Vogel, Peter;
Neale, Geoffrey;
Chi, Hongbo

Publication type:

Article

c-Myc and AP4: a relay team for metabolic reprogramming of CD8+ T cells.

Published in:

Nature Immunology, 2014, v. 15, n. 9, p. 828, doi. 10.1038/ni.2962

By:

Karmaus, Peer W F;
Chi, Hongbo

Publication type:

Article

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.

Published in:

Nature Immunology, 2014, v. 15, n. 5, p. 473, doi. 10.1038/ni.2849

By:

Mahmud, Shawn A;
Manlove, Luke S;
Schmitz, Heather M;
Xing, Yan;
Wang, Yanyan;
Owen, David L;
Schenkel, Jason M;
Boomer, Jonathan S;
Green, Jonathan M;
Yagita, Hideo;
Chi, Hongbo;
Hogquist, Kristin A;
Farrar, Michael A

Publication type:

Article

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

Published in:

Nature Immunology, 2013, v. 14, n. 12, p. 1266, doi. 10.1038/ni.2741

By:

Keating, Rachael;
Hertz, Tomer;
Wehenkel, Marie;
Harris, Tarsha L;
Edwards, Benjamin A;
McClaren, Jennifer L;
Brown, Scott A;
Surman, Sherri;
Wilson, Zachary S;
Bradley, Philip;
Hurwitz, Julia;
Chi, Hongbo;
Doherty, Peter C;
Thomas, Paul G;
McGargill, Maureen A

Publication type:

Article

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.

Published in:

Nature Immunology, 2013, v. 14, n. 5, p. 480, doi. 10.1038/ni.2563

By:

Lupfer, Christopher;
Thomas, Paul G;
Anand, Paras K;
Vogel, Peter;
Milasta, Sandra;
Martinez, Jennifer;
Huang, Gonghua;
Green, Maggie;
Kundu, Mondira;
Chi, Hongbo;
Xavier, Ramnik J;
Green, Douglas R;
Lamkanfi, Mohamed;
Dinarello, Charles A;
Doherty, Peter C;
Kanneganti, Thirumala-Devi

Publication type:

Article

Signaling via the kinase p38? programs dendritic cells to drive TH17 differentiation and autoimmune inflammation.

Published in:

Nature Immunology, 2012, v. 13, n. 2, p. 152, doi. 10.1038/ni.2207

By:

Huang, Gonghua;
Wang, Yanyan;
Vogel, Peter;
Kanneganti, Thirumala-Devi;
Otsu, Kinya;
Chi, Hongbo

Publication type:

Article

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.

Published in:

Nature Immunology, 2011, v. 12, n. 9, p. 888, doi. 10.1038/ni.2068

By:

Yang, Kai;
Neale, Geoffrey;
Green, Douglas R;
He, Weifeng;
Chi, Hongbo

Publication type:

Article

Acetylation of MKP-1 and the Control of Inflammation.

Published in:

Science Signaling, 2008, v. 1, n. 41, p. 1, doi. 10.1126/scisignal.141pe44

By:

Hongbo Chi;
Flavell, Richard A.

Publication type:

Article

Effect of SARS-CoV-2 infection on liver function in patients with hepatitis B.

Published in:

BMC Infectious Diseases, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12879-024-10324-0

By:

Sun, Tong;
Chi, Hongbo;
Wang, Jing;
Zheng, Yufen;
Zhu, Hongguo;
Zhao, Jingxian;
Zhou, Kai;
Chen, Mengyuan;
Wang, Donglian;
Tung, Tao-Hsin;
Xu, Jiaqin;
Shen, Bo

Publication type:

Article

Lipid metabolism in dendritic cell biology.

Published in:

Immunological Reviews, 2023, v. 317, n. 1, p. 137, doi. 10.1111/imr.13215

By:

You, Zhiyuan;
Chi, Hongbo

Publication type:

Article

mTOR signaling at the crossroads of environmental signals and T‐cell fate decisions.

Published in:

Immunological Reviews, 2020, v. 295, n. 1, p. 15, doi. 10.1111/imr.12845

By:

Huang, Hongling;
Long, Lingyun;
Zhou, Peipei;
Chapman, Nicole M.;
Chi, Hongbo

Publication type:

Article

Editorial: Hippo Signaling in the Immune System.

Published in:

2020

By:

Chen, Lanfen;
Chi, Hongbo;
Kinashi, Tatsuo

Publication type:

Editorial

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04392-5

By:

Chapman, Nicole M.;
Hu Zeng;
Nguyen, Thanh-Long M.;
Yanyan Wang;
Vogel, Peter;
Dhungana, Yogesh;
Xiaojing Liu;
Neale, Geoffrey;
Locasale, Jason W.;
Hongbo Chi

Publication type:

Article

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01388-5

By:

Mei Yu;
Yuhong Chen;
Hu Zeng;
Yongwei Zheng;
Guoping Fu;
Wen Zhu;
Broeckel, Ulrich;
Aggarwal, Praful;
Turner, Amy;
Neale, Geoffrey;
Guy, Cliff;
Nan Zhu;
Hongbo Chi;
Renren Wen;
Demin Wan

Publication type:

Article

De novo HBB frameshift mutation in a patient with dominant β‐thalassemia major.

Published in:

International Journal of Laboratory Hematology, 2022, v. 44, n. 1, p. e21, doi. 10.1111/ijlh.13669

By:

Zhou, Xiaoman;
Chen, Tongtong;
Zhang, Qianqian;
Qi, Ming;
Zhang, Li;
Du, Juping;
Chi, Hongbo;
Shen, Bo;
Xu, Xiangmin;
Lu, Yang

Publication type:

Article

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection.

Published in:

EMBO Journal, 2013, v. 32, n. 6, p. 816, doi. 10.1038/emboj.2013.28

By:

Mancino, Alessandra;
Habbeddine, Mohamed;
Johnson, Ella;
Luron, Lionel;
Bebien, Magali;
Memet, Sylvie;
Fong, Carol;
Bajenoff, Marc;
Wu, Xuefeng;
Karin, Michael;
Caamano, Jorge;
Chi, Hongbo;
Seed, Michael;
Lawrence, Toby

Publication type:

Article

GADD45ß/GADD45? and MEKK4 comprise a genetic pathway mediating STAT4-independent IFN? production in T cells.

Published in:

EMBO Journal, 2004, v. 23, n. 7, p. 1576, doi. 10.1038/sj.emboj.7600173

By:

Chi, Hongbo;
Lu, Binfeng;
Takekawa, Mutsuhiro;
Davis, Roger J.;
Flavell, Richard A.

Publication type:

Article

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells.

Published in:

Science Immunology, 2018, v. 3, n. 25, p. 1, doi. 10.1126/sciimmunol.aas9818

By:

Yang, Kai;
Blanco, Daniel Bastardo;
Chen, Xiang;
Dash, Pradyot;
Neale, Geoffrey;
Rosencrance, Celeste;
Easton, John;
Chen, Wenan;
Cheng, Changde;
Dhungana, Yogesh;
KC, Anil;
Awad, Walid;
Guo, Xi-Zhi J.;
Thomas, Paul G.;
Chi, Hongbo

Publication type:

Article

Estimating heterogeneity of car travelers on mode shifting behavior based on discrete choice models.

Published in:

Transportation Planning & Technology, 2017, v. 40, n. 8, p. 914, doi. 10.1080/03081060.2017.1355886

By:

Qin, Huanmei;
Gao, Jianqiang;
Guan, Hongzhi;
Chi, Hongbo

Publication type:

Article

Nutrient and Metabolic Sensing in T Cell Responses.

Published in:

Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00247

By:

Jun Wei;
Raynor, Jana;
Nguyen, Thanh-Long M.;
Hongbo Chi

Publication type:

Article

Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation.

Published in:

Cellular & Molecular Life Sciences, 2014, v. 71, n. 10, p. 1893, doi. 10.1007/s00018-013-1534-7

By:

Karmaus, Peer;
Chi, Hongbo

Publication type:

Article

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function.

Published in:

Nature, 2013, v. 499, n. 7459, p. 485, doi. 10.1038/nature12297

By:

Zeng, Hu;
Yang, Kai;
Cloer, Caryn;
Neale, Geoffrey;
Vogel, Peter;
Chi, Hongbo

Publication type:

Article

Longitudinal observation of viral load in patients infected with Omicron variant and its relationship with clinical symptoms.

Published in:

Frontiers in Microbiology, 2023, v. 13, p. 01, doi. 10.3389/fmicb.2022.1037733

By:

Kai Zhou;
Bingjie Hu;
Xinzhuan Zhao;
Hongbo Chi;
Juan Pan;
Yufen Zheng;
Xiaojie Bi;
Mengyuan Chen;
Jicheng Xie;
Jiaqin Xu;
Tao-Hsin Tung;
Bo Shen;
Hongguo Zhu

Publication type:

Article