Works by Homicsko, Krisztian

Results: 23

Patient-derived mini-colons enable long-term modeling of tumor–microenvironment complexity.

Published in:

Nature Biotechnology, 2025, v. 43, n. 5, p. 727, doi. 10.1038/s41587-024-02301-4

By:

Lorenzo-Martín, L. Francisco;
Broguiere, Nicolas;
Langer, Jakob;
Tillard, Lucie;
Nikolaev, Mikhail;
Coukos, George;
Homicsko, Krisztian;
Lutolf, Matthias P.

Publication type:

Article

In Vitro Evaluation of the Safety and Efficacy of Cibisatamab Using Adult Stem Cell-Derived Organoids and Colorectal Cancer Spheroids.

Published in:

Cancers, 2025, v. 17, n. 2, p. 291, doi. 10.3390/cancers17020291

By:

Anstett, Victor;
Heinzelmann, Elisa;
Piraino, Francesco;
Roch, Aline;
Chrisnandy, Antonius;
Norkin, Maxim;
Garnier, Virginie;
Homicsko, Krisztian;
Hoehnel-Ka, Sylke;
Brandenberg, Nathalie

Publication type:

Article

Estimated Costs of the Ipilimumab–Nivolumab Therapy and Related Adverse Events in Metastatic Melanoma.

Published in:

Cancers, 2023, v. 15, n. 1, p. 31, doi. 10.3390/cancers15010031

By:

Gautron Moura, Bianca;
Gerard, Camille L.;
Testart, Nathalie;
Caikovski, Marian;
Wicky, Alexandre;
Aedo-Lopez, Veronica;
Berthod, Grégoire;
Homicsko, Krisztian;
Prior, John O.;
Dromain, Clarisse;
Kandalaft, Lana E.;
Cuendet, Michel A.;
Michielin, Olivier

Publication type:

Article

Proton Pump Inhibitor Use and Efficacy of Nivolumab and Ipilimumab in Advanced Melanoma.

Published in:

Cancers, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/cancers14092300

By:

Homicsko, Krisztian;
Dummer, Reinhard;
Hoeller, Christoph;
Wolchok, Jedd D.;
Hodi, F. Stephen;
Larkin, James;
Ascierto, Paolo A.;
Atkinson, Victoria;
Robert, Caroline;
Postow, Michael A.;
Re, Sandra;
Paulucci, David;
Dobler, Darin;
Michielin, Olivier

Publication type:

Article

Safety and Efficacy of Ipilimumab plus Nivolumab and Sequential Selective Internal Radiation Therapy in Hepatic and Extrahepatic Metastatic Uveal Melanoma.

Published in:

Cancers, 2022, v. 14, n. 5, p. 1162, doi. 10.3390/cancers14051162

By:

Aedo-Lopez, Veronica;
Gérard, Camille L.;
Boughdad, Sarah;
Gautron Moura, Bianca;
Berthod, Gregoire;
Digklia, Antonia;
Homicsko, Krisztian;
Schaefer, Niklaus;
Duran, Rafael;
Cuendet, Michel A.;
Michielin, Olivier

Publication type:

Article

Deep and lasting response and acquired resistance to BRAFV600E targeting in a low-grade ovarian cancer patient.

Published in:

Cancer Biology & Therapy, 2023, v. 24, n. 1, p. 1, doi. 10.1080/15384047.2023.2193116

By:

Anchisi, Sandro;
Wolfer, Anita;
Bisig, Bettina;
Missiglia, Edoardo;
Tia, Amine;
Kamel, Ehab Mohamed;
Michielin, Olivier;
Coukos, George;
Homicsko, Krisztian

Publication type:

Article

Durable response to palbociclib and letrozole in ovarian cancer with CDKN2A loss.

Published in:

2020

By:

Frisone, Daniele;
Charrier, Melinda;
Clement, Sophie;
Christinat, Yann;
Thouvenin, Laure;
Homicsko, Krisztian;
Michielin, Olivier;
Bodmer, Alexandre;
Chappuis, Pierre O.;
McKee, Thomas A.;
Tsantoulis, Petros

Publication type:

Report

Strategies for clinical development of monoclonal antibodies beyond first-in-human trials: tested doses and rationale for dose selection.

Published in:

2018

By:

Viala, Marie;
Vinches, Marie;
Alexandre, Marie;
Mollevi, Caroline;
Durigova, Anna;
Hayaoui, Nadia;
Homicsko, Krisztian;
Cuenant, Alice;
Gongora, Céline;
Gianni, Luca;
Tosi, Diego;
Gongora, Céline

Publication type:

journal article

Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-55969-w

By:

Sun, Mengzhu;
Garnier, Laure;
Chevalier, Romane;
Roumain, Martin;
Wang, Chen;
Angelillo, Julien;
Montorfani, Julien;
Pick, Robert;
Brighouse, Dale;
Fournier, Nadine;
Tarussio, David;
Tissot, Stéphanie;
Lobaccaro, Jean-Marc;
Petrova, Tatiana V.;
Jandus, Camilla;
Speiser, Daniel E.;
Kopf, Manfred;
Pot, Caroline;
Scheiermann, Christoph;
Homicsko, Krisztian

Publication type:

Article

The consensus molecular subtypes of colorectal cancer.

Published in:

Nature Medicine, 2015, v. 21, n. 11, p. 1350, doi. 10.1038/nm.3967

By:

Guinney, Justin;
Dienstmann, Rodrigo;
Wang, Xin;
de Reyniès, Aurélien;
Schlicker, Andreas;
Soneson, Charlotte;
Marisa, Laetitia;
Roepman, Paul;
Nyamundanda, Gift;
Angelino, Paolo;
Bot, Brian M;
Morris, Jeffrey S;
Simon, Iris M;
Gerster, Sarah;
Fessler, Evelyn;
De Sousa E Melo, Felipe;
Missiaglia, Edoardo;
Ramay, Hena;
Barras, David;
Homicsko, Krisztian

Publication type:

Article

A colorectal cancer classification system that associates cellular phenotype and responses to therapy.

Published in:

Nature Medicine, 2013, v. 19, n. 5, p. 619, doi. 10.1038/nm.3175

By:

Sadanandam, Anguraj;
Lyssiotis, Costas A;
Homicsko, Krisztian;
Collisson, Eric A;
Gibb, William J;
Wullschleger, Stephan;
Ostos, Liliane C Gonzalez;
Lannon, William A;
Grotzinger, Carsten;
Del Rio, Maguy;
Lhermitte, Benoit;
Olshen, Adam B;
Wiedenmann, Bertram;
Cantley, Lewis C;
Gray, Joe W;
Hanahan, Douglas

Publication type:

Article

Nanoplasmonic Single‐Tumoroid Microarray for Real‐Time Secretion Analysis (Adv. Sci. 34/2024).

Published in:

2024

By:

Liu, Yen‐Cheng;
Ansaryan, Saeid;
Tan, Jiayi;
Broguiere, Nicolas;
Lorenzo‐Martín, Luis Francisco;
Homicsko, Krisztian;
Coukos, George;
Lütolf, Matthias P.;
Altug, Hatice

Publication type:

Abstract

Nanoplasmonic Single‐Tumoroid Microarray for Real‐Time Secretion Analysis.

Published in:

Advanced Science, 2024, v. 11, n. 34, p. 1, doi. 10.1002/advs.202401539

By:

Liu, Yen‐Cheng;
Ansaryan, Saeid;
Tan, Jiayi;
Broguiere, Nicolas;
Lorenzo‐Martín, Luis Francisco;
Homicsko, Krisztian;
Coukos, George;
Lütolf, Matthias P.;
Altug, Hatice

Publication type:

Article

T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.

Published in:

Science Translational Medicine, 2018, v. 10, n. 436, p. 1, doi. 10.1126/scitranslmed.aan3311

By:

Neubert, Natalie J.;
Schmittnaegel, Martina;
Bordry, Natacha;
Nassiri, Sina;
Wald, Noémie;
Martignier, Christophe;
Tillé, Laure;
Homicsko, Krisztian;
Damsky, William;
Maby-El Hajjami, Hélène;
Klaman, Irina;
Danenberg, Esther;
Ioannidou, Kalliopi;
Kandalaft, Lana;
Coukos, George;
Hoves, Sabine;
Ries, Carola H.;
Fuertes Marraco, Silvia A.;
Foukas, Periklis G.;
De Palma, Michele

Publication type:

Article

Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells.

Published in:

BMC Cancer, 2006, v. 6, p. 236, doi. 10.1186/1471-2407-6-236

By:

Fuerer, Christophe;
Homicsko, Krisztian;
Lukashev, Alexander N;
Pittet, Anne-Laure;
Iggo, Richard D

Publication type:

Article

The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study.

Published in:

Journal of Neuro-Oncology, 2020, v. 146, n. 1, p. 181, doi. 10.1007/s11060-019-03363-0

By:

Martins, Filipe;
Schiappacasse, Luis;
Levivier, Marc;
Tuleasca, Constantin;
Cuendet, Michel A.;
Aedo-Lopez, Veronica;
Gautron Moura, Bianca;
Homicsko, Krisztian;
Bettini, Adrienne;
Berthod, Gregoire;
Gérard, Camille L.;
Wicky, Alexandre;
Bourhis, Jean;
Michielin, Olivier

Publication type:

Article

Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8<sup>+ </sup>T-myeloid cell networks in melanoma.

Published in:

Science Immunology, 2024, v. 9, n. 92, p. 1, doi. 10.1126/sciimmunol.adg7995

By:

Barras, David;
Ghisoni, Eleonora;
Chiffelle, Johanna;
Orcurto, Angela;
Dagher, Julien;
Fahr, Noémie;
Benedetti, Fabrizio;
Crespo, Isaac;
Grimm, Alizée J.;
Morotti, Matteo;
Zimmermann, Stefan;
Duran, Rafael;
Imbimbo, Martina;
de Olza, Maria Ochoa;
Navarro, Blanca;
Homicsko, Krisztian;
Bobisse, Sara;
Labes, Danny;
Tsourti, Zoe;
Andriakopoulou, Charitini

Publication type:

Article

Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.

Published in:

Science Translational Medicine, 2017, v. 9, n. 407, p. 1, doi. 10.1126/scitranslmed.aal4712

By:

Fankhauser, Manuel;
Broggi, Maria A. S.;
Potin, Lambert;
Bordry, Natacha;
Jeanbart, Laura;
Lund, Amanda W.;
Da Costa, Elodie;
Hauert, Sylvie;
Rincon-Restrepo, Marcela;
Tremblay, Christopher;
Cabello, Elena;
Homicsko, Krisztian;
Michielin, Olivier;
Hanahan, Douglas;
Speiser, Daniel E.;
Swartz, Melody A.

Publication type:

Article

Response and Resistance to Trametinib in MAP2K1-Mutant Triple-Negative Melanoma.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4520, doi. 10.3390/ijms24054520

By:

Krebs, Fanny Seraphine;
Moura, Bianca;
Missiaglia, Edoardo;
Aedo-Lopez, Veronica;
Michielin, Olivier;
Tsantoulis, Petros;
Bisig, Bettina;
Trimech, Mounir;
Zoete, Vincent;
Homicsko, Krisztian

Publication type:

Article

Trametinib Induces the Stabilization of a Dual GNAQ p.Gly48Leu- and FGFR4 p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8021, doi. 10.3390/ijms21218021

By:

Krebs, Fanny S.;
Gérard, Camille;
Wicky, Alexandre;
Aedo-Lopez, Veronica;
Missiaglia, Edoardo;
Bisig, Bettina;
Trimech, Mounir;
Michielin, Olivier;
Homicsko, Krisztian;
Zoete, Vincent

Publication type:

Article

Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed colorectal cancer tumoroids.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00661-3

By:

Dutta, Devanjali;
Lorenzo-Martín, L. Francisco;
Rivest, François;
Broguiere, Nicolas;
Tillard, Lucie;
Ragusa, Simone;
Brandenberg, Nathalie;
Höhnel, Sylke;
Saugy, Damien;
Rusakiewicz, Sylvie;
Homicsko, Krisztian;
Coukos, George;
Lutolf, Matthias P.

Publication type:

Article

1016. Retargeted Selectively Replicating Adenoviruses in Combination with Antiangiogenic Therapy for the Therapy of Colon Cancer

Published in:

2005

By:

Homicsko, Krisztian;
Lukashev, Alexander;
Iggo, Richard

Publication type:

Abstract

Case Report: Lasting complete response to pembrolizumab in mismatch repair-deficient cardiac sarcoma: a genomic characterization.

Published in:

2025

By:

Ferraro, Daniela A.;
Bisig, Bettina;
Rotzinger, David C.;
Pareja, Fresia;
Missiaglia, Edoardo;
Voutsadakis, Ioannis;
Homicsko, Krisztian;
Digklia, Antonia

Publication type:

Case Study