Works by Holthofer, Harry

Results: 68

High calcium diet down-regulates kidney angiotensin-converting enzyme in experimental renal failure.

Published in:

2004

By:

Pörsti, Ilkka;
Fan, Meng;
Kööbi, Peeter;
Jolma, Pasi;
Kalliovalkama, Jarkko;
Vehmas, Tuija I.;
Helin, Heikki;
Holthöfer, Harry;
Mervaala, Eero;
Nyman, Tuulikki;
Tikkanen, Ilkka;
Pörsti, Ilkka;
Kööbi, Peeter;
Holthöfer, Harry

Publication type:

journal article

Nephrinuria in diabetic nephropathy of type 1 diabetes.

Published in:

2003

By:

Pätäri, Anu;
Havana, Marika;
Taipale, Heidi;
Holthöfer, Harry;
Forsblom, Carol;
Groop, Per-Henrik;
Pätäri, Anu;
Holthöfer, Harry

Publication type:

journal article

A Simplified Method to Recover Urinary Vesicles for Clinical Applications, and Sample Banking.

Published in:

Scientific Reports, 2014, p. 7532, doi. 10.1038/srep07532

By:

Musante, Luca;
Tataruch, Dorota;
Gu, Dongfeng;
Benito-Martin, Alberto;
Calzaferri, Giulio;
Aherne, Sinead;
Holthofer, Harry

Publication type:

Article

Urine and Free Immunoglobulin Light Chains as Analytes for Serodiagnosis of Hantavirus Infection.

Published in:

Viruses (1999-4915), 2019, v. 11, n. 9, p. 809, doi. 10.3390/v11090809

By:

Hepojoki, Satu;
Kareinen, Lauri;
Strandin, Tomas;
Vaheri, Antti;
Holthöfer, Harry;
Mustonen, Jukka;
Mäkelä, Satu;
Hedman, Klaus;
Vapalahti, Olli;
Hepojoki, Jussi

Publication type:

Article

High Rate of Monoclonal Gammopathy among Immunocompetent Subjects with Primary Cytomegalovirus Infection.

Published in:

Clinical Infectious Diseases, 2002, v. 35, n. 11, p. 1430, doi. 10.1086/344465

By:

Bühler, Suvi;
Laitinen, Kalevi;
Holthöfer, Harry;
Järvinen, Asko;
Schauman, Knut-Olof;
Hedman, Klaus

Publication type:

Article

Body Mass Index (BMI) Is Associated with Microalbuminuria in Chinese Hypertensive Patients.

Published in:

International Journal of Environmental Research & Public Health, 2015, v. 12, n. 2, p. 1998, doi. 10.3390/ijerph120201998

By:

Xinyu Liu;
Yu Liu;
Youming Chen;
Yongqiang Li;
Xiaofei Shao;
Yan Liang;
Bin Li;
Holthöfer, Harry;
Guanjing Zhang;
Hequn Zou

Publication type:

Article

Association of Uric Acid with Metabolic Syndrome in Men, Premenopausal Women and Postmenopausal Women.

Published in:

International Journal of Environmental Research & Public Health, 2014, v. 11, n. 3, p. 2899, doi. 10.3390/ijerph110302899

By:

Yongqiang Li;
Shanying Chen;
Xiaofei Shao;
Jia Guo;
Xinyu Liu;
Aiqun Liu;
Ying Zhang;
Honglei Wang;
Bin Li;
Kangping Deng;
Qin Liu;
Holthöfer, Harry;
Hequn Zou

Publication type:

Article

Association between Metabolic Syndrome and Chronic Kidney Disease in Perimenopausal Women.

Published in:

International Journal of Environmental Research & Public Health, 2013, v. 10, n. 9, p. 3987, doi. 10.3390/ijerph10093987

By:

Yongqiang Li;
Liqin Zhao;
Youming Chen;
Aiqun Liu;
Xinyu Liu;
Xiaofei Shao;
Ying Zhang;
Honglei Wang;
Xiaohong Wang;
Bin Li;
Kangping Deng;
Qin Liu;
Holthöfer, Harry;
Hequn Zou

Publication type:

Article

Podocyte-associated proteins FAT, alpha-actinin-4 and filtrin are expressed in Langerhans islets of the pancreas.

Published in:

Molecular & Cellular Biochemistry, 2007, v. 294, n. 1, p. 117, doi. 10.1007/s11010-006-9251-2

By:

Johanna Rinta-Valkama;
Tuula Palmén;
Markus Lassila;
Harry Holthöfer

Publication type:

Article

Urinary extracellular vesicles. A promising shortcut to novel biomarker discoveries.

Published in:

Cell & Tissue Research, 2017, v. 369, n. 1, p. 217, doi. 10.1007/s00441-017-2621-0

By:

Barreiro, Karina;
Holthofer, Harry

Publication type:

Article

From genetics to personalized nephrology: kidney research at a tipping point.

Published in:

2017

By:

Huber, Tobias;
Holthofer, Harry

Publication type:

Editorial

Recovery of urinary nanovesicles from ultracentrifugation supernatants.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 6, p. 1425, doi. 10.1093/ndt/gfs564

By:

Musante, Luca;
Saraswat, Mayank;
Ravidà, Alessandra;
Byrne, Barry;
Holthofer, Harry

Publication type:

Article

Regulation of nephrin gene by the Ets transcription factor, GA-binding protein.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 4, p. 846, doi. 10.1093/ndt/gfs482

By:

Ristola, Mervi;
Arpiainen, Satu;
Shimokawa, Toshibumi;
Ra, Chisei;
Tienari, Jukka;
Saleem, Moin A.;
Holthöfer, Harry;
Lehtonen, Sanna

Publication type:

Article

Transcription of nephrin–Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation.

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 5, p. 1737, doi. 10.1093/ndt/gfr576

By:

Ristola, Mervi;
Arpiainen, Satu;
Saleem, Moin A.;
Holthöfer, Harry;
Lehtonen, Sanna

Publication type:

Article

Nephrinuria associates with multiple renal traits in type 2 diabetes.

Published in:

Nephrology Dialysis Transplantation, 2011, v. 26, n. 8, p. 2508, doi. 10.1093/ndt/gfq738

By:

Ng, Daniel P.K.;
Tai, Bee-Choo;
Tan, Elaine;
Leong, Helen;
Nurbaya, Siti;
Lim, Xiu-Li;
Chia, Kee-Seng;
Wong, Chia-Siong;
Lim, Wei-Yen;
Holthöfer, Harry

Publication type:

Article

β-Catenin mediates adriamycin-induced albuminuria and podocyte injury in adult mouse kidneys.

Published in:

Nephrology Dialysis Transplantation, 2010, v. 25, n. 8, p. 2437, doi. 10.1093/ndt/gfq076

By:

Heikkilä, Eija;
Juhila, Juuso;
Lassila, Markus;
Messing, Marcel;
Perälä, Nina;
Lehtonen, Eero;
Lehtonen, Sanna;
Sjef Verbeek, Joseph;
Holthofer, Harry

Publication type:

Article

ERA-EDTA Immunonephrology working group.

Published in:

Nephrology Dialysis Transplantation, 2010, v. 25, n. 5, p. 1706, doi. 10.1093/ndt/gfq070

By:

Coppo, Rosanna;
Daha, Mohamed R.;
Egido, Jesus;
El-Nahas, Meguid;
Feehally, John;
Floege, Juergen;
Gesualdo, Loreto;
Holthofer, Harry;
Remuzzi, Giuseppe;
Ronco, Pierre

Publication type:

Article

Epigenetic and microRNA-mediated regulation in diabetes.

Published in:

Nephrology Dialysis Transplantation, 2009, v. 24, n. 4, p. 1088

By:

Pirkko Muhonen;
Harry Holthofer

Publication type:

Article

The nephrin-based slit diaphragm: new insight into the signalling platform identifies targets for therapy.

Published in:

Nephrology Dialysis Transplantation, 2007, v. 22, n. 12, p. 3408, doi. 10.1093/ndt/gfm403

By:

Petri Aaltonen;
Harry Holthöfer

Publication type:

Article

Expression of filtrin in human glomerular diseases.

Published in:

Nephrology Dialysis Transplantation, 2007, v. 22, n. 7, p. 1903, doi. 10.1093/ndt/gfm135

By:

Ihalmo, Pekka;
Schmid, Holger;
Rastaldi, Maria Pia;
Mattinzoli, Deborah;
Langham, Robyn G.;
Luimula, Pauliina;
Kilpikari, Riika;
Lassila, Markus;
Gilbert, Richard E.;
Kerjaschki, Dontscho;
Kretzler, Matthias;
Holthöfer, Harry

Publication type:

Article

Diabetes with kidney injury may change the abundance and cargo of urinary extracellular vesicles.

Published in:

Frontiers in Endocrinology, 2023, v. 14, p. 1, doi. 10.3389/fendo.2023.1085133

By:

Dongfeng Gu;
Yanan Ding;
Xin Jiang;
Beili Shen;
Musante, Luca;
Holthofer, Harry;
Hequn Zou

Publication type:

Article

Expression of insulin-like growth factor binding protein-1 mRNA in human fetal kidney.

Published in:

Kidney International, 1992, v. 43, n. 3, p. 749

By:

Suikkari, Anne-Maria;
Leivo, Ilmo;
Kämäräinen, Meerit;
Holthöfer, Harry;
Seppälä, Markku;
Julkunen, Mervi;
Koistinen, Riitta

Publication type:

Article

A cell-type specific ganglioside of glomerular podocytes in rat kidney: An O-acetylated GD3.

Published in:

Kidney International, 1992, v. 43, n. 3, p. 624

By:

Reivinen, Jukka;
Holthöfer, Harry;
Miettinen, Aaro

Publication type:

Article

Interactions of low density lipoprotein with rat mesangial cells.

Published in:

Kidney International, 1989, v. 35, n. 5, p. 1168, doi. 10.1038/ki.1989.106

By:

Wasserman, James;
Santiago, Arthur;
Rifici, Vincent;
Holthofer, Harry;
Scharschmidt, Linda;
Epstein, Margaret;
Schlondorff, Detlef

Publication type:

Article

Association between non-alcoholic fatty liver disease and chronic kidney disease in population with prediabetes or diabetes.

Published in:

International Urology & Nephrology, 2014, v. 46, n. 9, p. 1785, doi. 10.1007/s11255-014-0796-9

By:

Li, Yongqiang;
Zhu, Shuangshuang;
Li, Bin;
Shao, Xiaofei;
Liu, Xinyu;
Liu, Aiqun;
Wu, Bifang;
Zhang, Ying;
Wang, Honglei;
Wang, Xiaohong;
Deng, Kangping;
Liu, Qin;
Huang, Min;
Liu, Hongmei;
Holthöfer, Harry;
Zou, Hequn

Publication type:

Article

Use and isolation of urinary exosomes as biomarkers for diabetic nephropathy.

Published in:

Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00149

By:

Musante, Luca;
Tataruch, Dorota Ewa;
Holthofer, Harry

Publication type:

Article

Capturing the Kidney Transcriptome by Urinary Extracellular Vesicles—From Pre-Analytical Obstacles to Biomarker Research.

Published in:

Genes, 2023, v. 14, n. 7, p. 1415, doi. 10.3390/genes14071415

By:

Barreiro, Karina;
Dwivedi, Om Prakash;
Rannikko, Antti;
Holthöfer, Harry;
Tuomi, Tiinamaija;
Groop, Per-Henrik;
Puhka, Maija

Publication type:

Article

Angiotensin II-induced proteinuria and expression of the podocyte slit pore membrane protein, nephrin.

Published in:

Nephrology Dialysis Transplantation, 2004, v. 19, n. 1, p. 262, doi. 10.1093/ndt/gfg509

By:

Robyn G. Langham;
Darren J. Kelly;
Alison J. Cox;
Renae M. Gow;
Harry Holthofer;
Richard E. Gilbert

Publication type:

Article

Expression of the slit‐diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti‐proteinuric therapies.

Published in:

Nephrology Dialysis Transplantation, 2002, v. 17, n. 7, p. 1327, doi. 10.1093/ndt/17.7.1327

By:

Kelly, Darren J.;
Aaltonen, Petri;
Cox, Alison J.;
Rumble, Jon R.;
Langham, Robyn;
Panagiotopoulos, Sianna;
Jerums, George;
Holthöfer, Harry;
Gilbert, Richard E.

Publication type:

Article

An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles.

Published in:

Journal of Extracellular Vesicles, 2023, v. 12, n. 2, p. 1, doi. 10.1002/jev2.12304

By:

Barreiro, Karina;
Lay, Abigail C.;
Leparc, German;
Tran, Van Du T.;
Rosler, Marcel;
Dayalan, Lusyan;
Burdet, Frederic;
Ibberson, Mark;
Coward, Richard J. M.;
Huber, Tobias B.;
Krämer, Bernhard K.;
Delic, Denis;
Holthofer, Harry

Publication type:

Article

Urinary extracellular vesicles: Assessment of pre‐analytical variables and development of a quality control with focus on transcriptomic biomarker research.

Published in:

Journal of Extracellular Vesicles, 2021, v. 10, n. 12, p. 1, doi. 10.1002/jev2.12158

By:

Barreiro, Karina;
Dwivedi, Om Prakash;
Valkonen, Sami;
Groop, Per‐Henrik;
Tuomi, Tiinamaija;
Holthofer, Harry;
Rannikko, Antti;
Yliperttula, Marjo;
Siljander, Pia;
Laitinen, Saara;
Serkkola, Elina;
af Hällström, Taija;
Forsblom, Carol;
Groop, Leif;
Puhka, Maija

Publication type:

Article

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles.

Published in:

Journal of Extracellular Vesicles, 2021, v. 10, n. 7, p. 1, doi. 10.1002/jev2.12093

By:

Erdbrügger, Uta;
Blijdorp, Charles J.;
Bijnsdorp, Irene V.;
Borràs, Francesc E.;
Burger, Dylan;
Bussolati, Benedetta;
Byrd, James Brian;
Clayton, Aled;
Dear, James W.;
Falcón‐Pérez, Juan M.;
Grange, Cristina;
Hill, Andrew F.;
Holthöfer, Harry;
Hoorn, Ewout J.;
Jenster, Guido;
Jimenez, Connie R.;
Junker, Kerstin;
Klein, John;
Knepper, Mark A.;
Koritzinsky, Erik H.

Publication type:

Article

Comparison of urinary extracellular vesicle isolation methods for transcriptomic biomarker research in diabetic kidney disease.

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, n. 2, p. 1, doi. 10.1002/jev2.12038

By:

Barreiro, Karina;
Dwivedi, Om Prakash;
Leparc, German;
Rolser, Marcel;
Delic, Denis;
Forsblom, Carol;
Groop, Per‐Henrik;
Groop, Leif;
Huber, Tobias B.;
Puhka, Maija;
Holthofer, Harry

Publication type:

Article

The future of Extracellular Vesicles as Theranostics – an ISEV meeting report.

Published in:

Journal of Extracellular Vesicles, 2020, v. 9, n. 1, p. 1, doi. 10.1080/20013078.2020.1809766

By:

Soekmadji, Carolina;
Li, Bo;
Huang, Yiyao;
Wang, Haifang;
An, Taixue;
Liu, Chunchen;
Pan, Weilun;
Chen, Jing;
Cheung, Lesley;
Falcon-Perez, Juan Manuel;
Gho, Yong Song;
Holthofer, Harry B.;
Le, Minh T. N.;
Marcilla, Antonio;
O'Driscoll, Lorraine;
Shekari, Faezeh;
Shen, Tang Long;
Torrecilhas, Ana Claudia;
Yan, Xiaomei;
Yang, Fuquan

Publication type:

Article

The future of Extracellular Vesicles as Theranostics – an ISEV meeting report.

Published in:

Journal of Extracellular Vesicles, 2020, v. 9, n. 1, p. 1, doi. 10.1080/20013078.2020.1809766

By:

Soekmadji, Carolina;
Li, Bo;
Huang, Yiyao;
Wang, Haifang;
An, Taixue;
Liu, Chunchen;
Pan, Weilun;
Chen, Jing;
Cheung, Lesley;
Falcon‐Perez, Juan Manuel;
Gho, Yong Song;
Holthofer, Harry B.;
Le, Minh T. N.;
Marcilla, Antonio;
O'Driscoll, Lorraine;
Shekari, Faezeh;
Shen, Tang Long;
Torrecilhas, Ana Claudia;
Yan, Xiaomei;
Yang, Fuquan

Publication type:

Article

Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.

Published in:

Journal of Extracellular Vesicles, 2017, v. 6, n. 1, p. N.PAG, doi. 10.1080/20013078.2016.1267896

By:

Musante, Luca;
Tataruch-Weinert, Dorota;
Kerjaschki, Dontscho;
Henry, Michael;
Meleady, Paula;
Holthofer, Harry

Publication type:

Article

Urinary extracellular vesicles for RNA extraction: optimization of a protocol devoid of prokaryote contamination.

Published in:

Journal of Extracellular Vesicles, 2016, v. 5, p. 1, doi. 10.3402/jev.v5.30281

By:

Tataruch-Weinert, Dorota;
Musante, Luca;
Kretz, Oliver;
Holthofer, Harry

Publication type:

Article

Correlation of visceral adiposity index with chronic kidney disease in the People's Republic of China: to rediscover the new clinical potential of an old indicator for visceral obesity.

Published in:

2016

By:

Xiaomeng Xu;
Yan Zhao;
Zhihong Zhao;
Shuangshuang Zhu;
Xinyu Liu;
Chaomin Zhou;
Xiaofei Shao;
Yan Liang;
Chongyang Duan;
Holthöfer, Harry;
Hequn Zou;
Xu, Xiaomeng;
Zhao, Yan;
Zhao, Zhihong;
Zhu, Shuangshuang;
Liu, Xinyu;
Zhou, Chaomin;
Shao, Xiaofei;
Liang, Yan;
Duan, Chongyang

Publication type:

journal article

Insulin resistance and metabolic syndrome in normal-weight individuals.

Published in:

Endocrine (1355008X), 2014, v. 46, n. 3, p. 496, doi. 10.1007/s12020-013-0079-8

By:

Chen, Shanying;
Chen, Youming;
Liu, Xinyu;
Li, Mi;
Wu, Bide;
Li, Yongqiang;
Liang, Yan;
Shao, Xiaofei;
Holthöfer, Harry;
Zou, Hequn

Publication type:

Article

Puromycin-induced Lipid Peroxidation in the Cochlea of ApoeE Knockout Mice.

Published in:

Acta Oto-Laryngologica (Supplement), 2000, v. 120, p. 102, doi. 10.1080/000164800454116

By:

Aarnisalo, Antti A.;
Aalto-Setälä, Katariina;
Holthöfer, Harry;
Ylikoski, Jukka

Publication type:

Article

Glomerular antigens in severe hereditary nephrosis.

Published in:

APMIS, 1995, v. 103, n. 7/8, p. 823, doi. 10.1111/j.1699-0463.1995.tb01441.x

By:

HOLTHÖFER, HARRY;
HALTIA, ANNI;
JALANKO, HANNU;
HOLMBERG, CHRISTER;
SOLIN, MARJA-LIISA

Publication type:

Article

The glomerular mesangium: studies of its developmental origin and markers in vivo and in vitro.

Published in:

APMIS, 1995, v. 103, n. 1-6, p. 354, doi. 10.1111/j.1699-0463.1995.tb01119.x

By:

HÖLthofer, HARRY;
Sainio, KIRSI;
Miettinen, AARO

Publication type:

Article

Proteases and Protease Inhibitors of Urinary Extracellular Vesicles in Diabetic Nephropathy.

Published in:

Journal of Diabetes Research, 2015, v. 2015, p. 1, doi. 10.1155/2015/289734

By:

Musante, Luca;
Tataruch, Dorota;
Gu, Dongfeng;
Liu, Xinyu;
Forsblom, Carol;
Groop, Per-Henrik;
Holthofer, Harry

Publication type:

Article

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins.

Published in:

Stem Cell Research & Therapy, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13287-019-1213-1

By:

Mitchell, Robert;
Mellows, Ben;
Sheard, Jonathan;
Antonioli, Manuela;
Kretz, Oliver;
Chambers, David;
Zeuner, Marie-Theres;
Tomkins, James E.;
Denecke, Bernd;
Musante, Luca;
Joch, Barbara;
Debacq-Chainiaux, Florence;
Holthofer, Harry;
Ray, Steve;
Huber, Tobias B.;
Dengjel, Joern;
De Coppi, Paolo;
Widera, Darius;
Patel, Ketan

Publication type:

Article

Stable expression of nephrin and localization to cell-cell contacts in novel murine podocyte cell lines.

Published in:

Kidney International, 2004, v. 66, n. 1, p. 91, doi. 10.1111/j.1523-1755.2004.00711.x

By:

Schiwek, Daniel;
Endlich, Nicole;
Holzman, Lawrence;
Holthöfer, Harry;
Kriz, Wilhelm;
Endlich, Karlhans

Publication type:

Article

Hypercholesterolemia is a prerequisite for puromycin inducible damage in mouse kidney.

Published in:

Kidney International, 2003, v. 63, n. 1, p. 107, doi. 10.1046/j.1523-1755.2003.00726.x

By:

Cheng, Zhu-Zhu;
Pätäri, Anu;
Aalto-Setälä, Katriina;
Novikov, Dmitry;
Schlöndorff, Detlef;
Holthöfer, Harry

Publication type:

Article

Patterns of nephrin and a new proteinuria-associated protein expression in human renal diseases.

Published in:

Kidney International, 2002, v. 61, n. 1, p. 141, doi. 10.1046/j.1523-1755.2002.00114.x

By:

Wang, Shi-Xuan;
Rastaldi, Maria P.;
Pätäri, Anu;
Ahola, Heikki;
Heikkilä, Eija;
Holthöfer, Harry

Publication type:

Article

Lipid peroxidation in human proteinuric disease.

Published in:

2001

By:

Solin, Marja-Lisa;
Ahola, Heikki;
Haltia, Anni;
Ursini, Fulvio;
Montine, Tom;
Roveri, Antonella;
Kerjaschki, Dontscho;
Holthöfer, Harry;
Solin, M L;
Ahola, H;
Haltia, A;
Ursini, F;
Montine, T;
Roveri, A;
Kerjaschki, D;
Holthöfer, H

Publication type:

journal article

Nephrin in experimental glomerular disease.

Published in:

Kidney International, 2000, v. 58, n. 4, p. 1461, doi. 10.1046/j.1523-1755.2000.00308.x

By:

Luimula, Paulina;
Ahola, Heikki;
Shi-Xuan Wang;
Solin, Marja-Liisa;
Aaltonen, Petri;
Tikkanen, Ilkka;
Kerjaschki, Dontscho;
Holthofer, Harry

Publication type:

Article

Nephrin localizes to the slit pore of the glomerular epithelial cell.

Published in:

Kidney International, 1999, v. 56, n. 4, p. 1481, doi. 10.1046/j.1523-1755.1999.00719.x

By:

Holzman, Lawrence B.;
John, Patricia L. ST.;
Kovari, Iulia A.;
Verma, Rakesh;
Holthofer, Harry;
Abrahamson, Dale R.

Publication type:

Article