Works by Holsboer F

Results: 70

Diurnal variations in the human host response to endotoxin.

Published in:

1996

By:

Pollmächer T;
Mullington J;
Korth C;
Schreiber W;
Hermann D;
Orth A;
Galanos C;
Holsboer F;
Pollmächer, T;
Mullington, J;
Korth, C;
Schreiber, W;
Hermann, D;
Orth, A;
Galanos, C;
Holsboer, F

Publication type:

journal article

Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool.

Published in:

Translational Psychiatry, 2017, v. 7, n. 1, p. e990, doi. 10.1038/tp.2016.255

By:

Yu, S;
Zutshi, I;
Stoffel, R;
Zhang, J;
Ventura-Silva, A P;
Sousa, N;
Costa, P S;
Holsboer, F;
Patchev, A;
Almeida, O F X

Publication type:

Article

Proliferation rates and gene expression profiles in human lymphoblastoid cell lines from patients with depression characterized in response to antidepressant drug therapy.

Published in:

Translational Psychiatry, 2016, v. 6, n. 11, p. e950, doi. 10.1038/tp.2016.185

By:

Breitfeld, J;
Scholl, C;
Steffens, M;
Brandenburg, K;
Probst-Schendzielorz, K;
Efimkina, O;
Gurwitz, D;
Ising, M;
Holsboer, F;
Lucae, S;
Stingl, J C

Publication type:

Article

Bidirectional effects of the neuroactive steroid tetrahydrodeoxycorticosterone on GABA-activated Cl− currents in cultured rat hypothalamic neurons.

Published in:

British Journal of Pharmacology, 1999, v. 127, n. 4, p. 863, doi. 10.1038/sj.bjp.0702597

By:

Wetzel, C H R;
Vedder, H;
Holsboer, F;
Zieglgänsberger, W;
Deisz, R A

Publication type:

Article

Family history of depression is associated with younger age of onset in patients with recurrent depression.

Published in:

2008

By:

Tozzi F;
Prokopenko I;
Perry JD;
Kennedy JL;
McCarthy AD;
Holsboer F;
Berrettini W;
Middleton LT;
Chilcoat HD;
Muglia P

Publication type:

Journal Article

Family history of depression is associated with younger age of onset in patients with recurrent depression.

Published in:

Psychological Medicine, 2008, v. 38, n. 5, p. 641, doi. 10.1017/S0033291707002681

By:

Tozzi, F.;
Prokopenko, I.;
Perry, J. D.;
Kennedy, J. L.;
McCarthy, A. D.;
Holsboer, F.;
Berrettini, W.;
Middleton, L. T.;
Chilcoat, H. D.;
Muglia, P.

Publication type:

Article

The stress hormone system is back on the map.

Published in:

2000

By:

Holsboer, Florian;
Holsboer, F

Publication type:

journal article

SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system.

Published in:

Stress: The International Journal on the Biology of Stress, 2016, v. 19, n. 1, p. 83, doi. 10.3109/10253890.2015.1105211

By:

Santarelli, S.;
Wagner, K. V.;
Labermaier, C.;
Uribe, A.;
Dournes, C.;
Balsevich, G.;
Hartmann, J.;
Masana, M.;
Holsboer, F.;
Chen, A.;
Müller, M. B.;
Schmidt, M. V.

Publication type:

Article

Maintenance of Hippocampal Cell Numbers in Young and Aged Rats Submitted to Chronic Unpredictable Stress. Comparison with the Effects of Corticosterone Treatment.

Published in:

Stress: The International Journal on the Biology of Stress, 1998, v. 2, n. 4, p. 237, doi. 10.3109/10253899809167288

By:

Sousa, N.;
Almeida, O. F. X.;
Holsboer, F.;
Paula-Barbosa, M. M.;
Madeira, M. D.

Publication type:

Article

RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response.

Published in:

European Psychiatry, 2016, v. 33, p. S210, doi. 10.1016/j.eurpsy.2016.01.394

By:

Hennings, J.;
Uhr, M.;
Klengel, T.;
Weber, P.;
Pütz, B.;
Touma, C.;
Darina, C.;
Ising, M.;
Holsboer, F.;
Lucae, S.

Publication type:

Article

RSUME inhibits VHL and regulates its tumor suppressor function.

Published in:

Oncogene, 2015, v. 34, n. 37, p. 4855, doi. 10.1038/onc.2014.407

By:

Gerez, J;
Tedesco, L;
Bonfiglio, J J;
Fuertes, M;
Barontini, M;
Silberstein, S;
Wu, Y;
Renner, U;
Páez-Pereda, M;
Holsboer, F;
Stalla, G K;
Arzt, E

Publication type:

Article

More CLEC16A gene variants associated with multiple sclerosis.

Published in:

Acta Neurologica Scandinavica, 2011, v. 123, n. 6, p. 400, doi. 10.1111/j.1600-0404.2010.01421.x

By:

Nischwitz, S.;
Cepok, S.;
Kroner, A.;
Wolf, C.;
Knop, M.;
Müller-Sarnowski, F.;
Pfister, H.;
Rieckmann, P.;
Hemmer, B.;
Ising, M.;
Uhr, M.;
Bettecken, T.;
Holsboer, F.;
Müller-Myhsok, B.;
Weber, F.

Publication type:

Article

Intrahippocampal Corticosterone Response in Mice Selectively Bred for Extremes in Stress Reactivity: A Microdialysis Study J.-M. Heinzmann et al. Stress-induced intrahippocampal corticosterone response.

Published in:

Journal of Neuroendocrinology, 2010, v. 22, n. 11, p. 1187, doi. 10.1111/j.1365-2826.2010.02062.x

By:

Heinzmann, J.-M.;
Thoeringer, C.-K.;
Knapman, A.;
Palme, R.;
Holsboer, F.;
Uhr, M.;
Landgraf, R.;
Touma, C.

Publication type:

Article

Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression.

Published in:

2010

By:

Kloiber, S;
Kohli, MA;
Brueckl, T;
Ripke, S;
Ising, M;
Uhr, M;
Menke, A;
Unschuld, PG;
Horstmann, S;
Salyakina, D;
Muller-Myhsok, B;
Binder, EB;
Holsboer, F;
Lucae, S

Publication type:

Correction Notice

Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression.

Published in:

Molecular Psychiatry, 2010, v. 15, n. 7, p. 736, doi. 10.1038/mp.2008.142

By:

Kloiber, S.;
Kohli, M. A.;
Brueckl, T.;
Ripke, S.;
Ising, M.;
Uhr, M.;
Menke, A.;
Unschuld, P. G.;
Horstmann, S.;
Salyakina, D.;
Muller-Myhsok, B.;
Binder, E. B.;
Holsboer, F.;
Lucae, S.

Publication type:

Article

Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways.

Published in:

Molecular Psychiatry, 2010, v. 15, n. 7, p. 702, doi. 10.1038/mp.2008.146

By:

Ditzen, C.;
Varadarajulu, J.;
Czibere, L.;
Gonik, M.;
Targosz, B. S.;
Hambsch, B.;
Bettecken, T.;
Keßler, M. S.;
Frank, E.;
Bunck, M.;
Teplytska, L.;
Erhardt, A.;
Holsboer, F.;
Müller-Myhsok, B.;
Landgraf, R.;
Turck, C. W.

Publication type:

Article

Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts.

Published in:

Molecular Psychiatry, 2010, v. 15, n. 6, p. 589, doi. 10.1038/mp.2008.131

By:

Muglia, P.;
Tozzi, F.;
Galwey, N. W.;
Francks, C.;
Upmanyu, R.;
Kong, X. Q.;
Antoniades, A.;
Domenici, E.;
Perry, J.;
Rothen, S.;
Vandeleur, C. L.;
Mooser, V.;
Waeber, G.;
Vollenweider, P.;
Preisig, M.;
Lucae, S.;
Müller-Myhsok, B.;
Holsboer, F.;
Middleton, L. T.;
Roses, A. D.

Publication type:

Article

Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep.

Published in:

Molecular Psychiatry, 2010, v. 15, n. 2, p. 154, doi. 10.1038/mp.2009.46

By:

Kimura, M.;
Müller-Preuss, P.;
Lu, A.;
Wiesner, E.;
Flachskamm, C.;
Wurst, W.;
Holsboer, F.;
Deussing, J. M.

Publication type:

Article

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo.

Published in:

Molecular Psychiatry, 2009, v. 14, n. 4, p. 359, doi. 10.1038/mp.2008.125

By:

Sullivan, P. F.;
de Geus, E. J. C.;
Willemsen, G.;
James, M. R.;
Smit, J. H.;
Zandbelt, T.;
Arolt, V.;
Baune, B. T.;
Blackwood, D.;
Cichon, S.;
Coventry, W. L.;
Domschke, K.;
Farmer, A.;
Fava, M.;
Gordon, S. D.;
He, Q.;
Heath, A. C.;
Heutink, P.;
Holsboer, F.;
Hoogendijk, W. J.

Publication type:

Article

Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system.

Published in:

Molecular Psychiatry, 2008, v. 13, n. 11, p. 989, doi. 10.1038/mp.2008.107

By:

Lu, A;
Steiner, M A;
Whittle, N;
Vogl, A M;
Walser, S M;
Ableitner, M;
Refojo, D;
Ekker, M;
Rubenstein, J L;
Stalla, G K;
Singewald, N;
Holsboer, F;
Wotjak, C T;
Wurst, W;
Deussing, J M

Publication type:

Article

Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.

Published in:

Molecular Psychiatry, 2008, v. 13, n. 11, p. 1028, doi. 10.1038/mp.2008.51

By:

Lu, A;
Steiner, M A;
Whittle, N;
Vogl, A M;
Walser, S M;
Ableitner, M;
Refojo, D;
Ekker, M;
Rubenstein, J L;
Stalla, G K;
Singewald, N;
Holsboer, F;
Wotjak, C T;
Wurst, W;
Deussing, J M

Publication type:

Article

Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism.

Published in:

Molecular Psychiatry, 2008, v. 13, n. 9, p. 831, doi. 10.1038/mp.2008.2

By:

Heck, A;
Lieb, R;
Unschuld, P G;
Ellgas, A;
Pfister, H;
Lucae, S;
Erhardt, A;
Himmerich, H;
Horstmann, S;
Kloiber, S;
Ripke, S;
Müller-Myhsok, B;
Bettecken, T;
Uhr, M;
Holsboer, F;
Ising, M

Publication type:

Article

Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks.

Published in:

2008

By:

Erhardt, A.;
Lucae, S.;
Kern, N.;
Unschuld, P. G.;
Ising, M.;
Lieb, R.;
Uhr, M.;
Hohoff, C.;
Deckert, J.;
Bandelow, B.;
Maier, W.;
Binder, E. B.;
Müller-Myhsok, B.;
Keck, M. E.;
Holsboer, F.

Publication type:

Letter

Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism.

Published in:

Molecular Psychiatry, 2006, v. 11, n. 11, p. 1003, doi. 10.1038/sj.mp.4001884

By:

Baghai, T. C.;
Binder, E. B.;
Schule, C.;
Salyakina, D.;
Eser, D.;
Lucae, S.;
Zwanzger, P.;
Haberger, C.;
Zill, P.;
Ising, M.;
Deiml, T.;
Uhr, M.;
Illig, T.;
Wichmann, H.-E.;
Modell, S.;
Nothdurfter, C.;
Holsboer, F.;
Müller-Myhsok, B.;
Möller, H.-J.;
Rupprecht, R.

Publication type:

Article

Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation.

Published in:

Molecular Psychiatry, 2005, v. 10, n. 8, p. 790, doi. 10.1038/sj.mp.4001679

By:

Crochemore, C.;
Lu, J.;
Wu, Y.;
Liposits, Z.;
Sousa, N.;
Holsboer, F.;
Almeida, O. F. X.

Publication type:

Article

Antipsychotic drugs antagonize human serotonin type 3 receptor currents in a noncompetitive manner.

Published in:

Molecular Psychiatry, 2004, v. 9, n. 9, p. 846, doi. 10.1038/sj.mp.4001490

By:

Rammes, G.;
Eisensamerh, B.;
Ferrari, U.;
Shapa, M.;
Gimpl, G.;
Gilling, K.;
Parsons, C.;
Riering, K.;
Hapfelmeier, G.;
Bondy, B.;
Zieglgànsberger, W.;
Holsboer, F.;
Rupprecht, R.

Publication type:

Article

Antipsychotic drugs antagonise human serotonin type 3 (5-HT3) receptor currents in a noncompetitive manner.

Published in:

Molecular Psychiatry, 2004, v. 9, n. 9, p. 818, doi. 10.1038/sj.mp.4001567

By:

Rammes, G.;
Eisensamer, B.;
Ferrari, U.;
Shapa, M.;
Gimpl, G.;
Gilling, K.;
Parsons, C.;
Riering, K.;
Hapfelmeier, G.;
Bondy, B.;
Zieglgànsberger, W.;
Holsboer, F.;
Rupprecht, R.

Publication type:

Article

Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptor.

Published in:

Molecular Psychiatry, 2003, v. 8, n. 12, p. 994, doi. 10.1038/sj.mp.4001314

By:

Eisensamer, B.;
Rammes, G.;
Gimpl, G.;
Shapa, M.;
Ferrari, U.;
Hapfelmeier, G.;
Bondy, B.;
Parsons, C.;
Gilling, K.;
Zieglgänsberger, W.;
Holsboer, F.;
Rupprecht, R.

Publication type:

Article

Effects of transgenic overproduction of CRH on anxiety-like behaviour.

Published in:

2002

By:

Van Gaalen, M.M.;
Stenzel‐Poore, M.P.;
Holsboer, F.;
Steckler, T.

Publication type:

Erratum

Forced swimming evokes a biphasic response in CREB phosphorylation in extrahypothalamic limbic and neocortical brain structures in the rat.

Published in:

European Journal of Neuroscience, 2002, v. 15, n. 6, p. 1048, doi. 10.1046/j.1460-9568.2002.01934.x

By:

Bilang‐Bleuel, A.;
Rech, J.;
De Carli, S.;
Holsboer, F.;
Reul, J. M. H. M.

Publication type:

Article

Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo.

Published in:

European Journal of Neuroscience, 2000, v. 12, n. 10, p. 3721, doi. 10.1046/j.1460-9568.2000.00229.x

By:

Do, K. Q.;
Trabesinger, A. H.;
Kirsten‐Krüger, M.;
Lauer, C. J.;
Dydak, U.;
Hell, D.;
Holsboer, F.;
Boesiger, P.;
Cuénod, M.

Publication type:

Article

The Munich vulnerability study on affective disorders: premorbid psychometric profile of affected individuals.

Published in:

Acta Psychiatrica Scandinavica, 2004, v. 109, n. 5, p. 332, doi. 10.1111/j.1600-0447.2004.00309.x

By:

Ising, M.;
Lauer, C. J.;
Holsboer, F.;
Modell, S.

Publication type:

Article

Studies of nocturnal penile tumescence and sleep electroencephalogram in patients with major depression and in normal controls.

Published in:

Acta Psychiatrica Scandinavica, 1993, v. 87, n. 5, p. 358, doi. 10.1111/j.1600-0447.1993.tb03387.x

By:

Steiger, A.;
Holsboer, F.;
Benkert, O.

Publication type:

Article

Brain activation and hypothalamic functional connectivity during human non-rapid eye movement sleep: an EEG/fMRI study.

Published in:

Brain: A Journal of Neurology, 2006, v. 129, n. 3, p. 655, doi. 10.1093/brain/awh686

By:

C. Kaufmann;
R. Wehrle;
T. C. Wetter;
F. Holsboer;
D. P. Auer;
T. Pollmächer;
M. Czisch

Publication type:

Article

Inhibition of lipopolysaccharide-induced monocyte interleukin-1 receptor antagonist synthesis by cortisol: involvement of the mineralocorticoid receptor.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1996, v. 81, n. 1, p. 73, doi. 10.1210/jc.81.1.73

By:

SAUER, J.;
CASTREN, M.;
HOPFNER, U.;
HOLSBOER, F.;
STALLA, G. K.;
ARZT, E.

Publication type:

Article

Cerebrospinal fluid concentrations of corticotropin-releasing hormone, vasopressin, and somatostatin in depressed patients and healthy controls: Response to amitriptyline treatment.

Published in:

Depression & Anxiety (1091-4269), 1998, v. 8, n. 2, p. 71, doi. 10.1002/(SICI)1520-6394(1998)8:2<71::AID-DA5>3.0.CO;2-N

By:

Heuser, I.;
Bissette, G.;
Dettling, M.;
Schweiger, U.;
Gotthardt, U.;
Schmider, J.;
Lammers, C. H.;
Nemeroff, C. B.;
Holsboer, F.

Publication type:

Article

Die Zukunft der Depressionsforschung.

Published in:

Der Nervenarzt, 2010, v. 81, n. 11, p. 1306, doi. 10.1007/s00115-010-3053-1

By:

Holsboer, F.

Publication type:

Article

γ-Glutamylglutamine and Taurine Concentrations Are Decreased in the Cerebrospinal Fluid of Drug-Naive Patients with Schizophrenic Disorders.

Published in:

Journal of Neurochemistry, 1995, v. 65, n. 6, p. 2652, doi. 10.1046/j.1471-4159.1995.65062652.x

By:

Do, K. Q.;
Lauer, C. J.;
Schreiber, W.;
Zollinger, M.;
Gutteck-Amsler, U.;
Cuénod, M.;
Holsboer, F.

Publication type:

Article

Effects of clozapine on in vitro immune parameters: a longitudinal study in clozapine-treated...

Published in:

2000

By:

Hinze-Selch, D;
Becker, EW;
Stein, GM;
Berg, PA;
Mullington, J;
Holsboer, F;
Pollmacher, T

Publication type:

Abstract

Alterations of nocturnal sleep in patients with HIV infection.

Published in:

Acta Neurologica Scandinavica, 1991, v. 83, n. 2, p. 141, doi. 10.1111/j.1600-0404.1991.tb04664.x

By:

Wiegand, M.;
Möller, A. A.;
Schreiber, W.;
Krieg, J.-C.;
Holsboer, F.

Publication type:

Article

The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.

Published in:

Journal of Neural Transmission, 2009, v. 116, n. 6, p. 649, doi. 10.1007/s00702-008-0075-y

By:

Thoeringer, C. K.;
Ripke, S.;
Unschuld, P. G.;
Lucae, S.;
Ising, M.;
Bettecken, T.;
Uhr, M.;
Keck, M. E.;
Mueller-Myhsok, B.;
Holsboer, F.;
Binder, E. B.;
Erhardt, A.

Publication type:

Article

Antidepressants do not modulate estrogen receptor α-mediated gene expression.

Published in:

Journal of Neural Transmission, 2001, v. 108, n. 10, p. 1197, doi. 10.1007/s007020170009

By:

Hermann, B.;
Vollmer, I.;
Holsboer, F.;
Rupprecht, R.

Publication type:

Article

Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders.

Published in:

2004

By:

Majer M;
Ising M;
Künzel H;
Binder EB;
Holsboer F;
Modell S;
Zihl J

Publication type:

Journal Article

Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders.

Published in:

Psychological Medicine, 2004, v. 34, n. 8, p. 1453, doi. 10.1017/S0033291704002697

By:

Majer, M.;
Ising, M.;
Künzel, H.;
Binder, E. B.;
Holsboer, F.;
Modell, S.;
Zihl, J.

Publication type:

Article

Pre-morbid psychometric profile of subjects at high familial risk for affective disorder.

Published in:

Psychological Medicine, 1997, v. 27, n. 2, p. 355, doi. 10.1017/S0033291796004400

By:

C. J. LAUER;
T. BRONISCH;
M. KAINZ;
W. SCHREIBER;
F. HOLSBOER;
J.-C. KRIEG

Publication type:

Article

Dexamethasone suppression test in severe schizophrenic illness: Effects of plasma dexamethasone and caffeine levels.

Published in:

Acta Psychiatrica Scandinavica, 1987, v. 75, n. 6, p. 608, doi. 10.1111/j.1600-0447.1987.tb02844.x

By:

Holsboer-Trachsler, E.;
Buol, C.;
Wiedemann, K.;
Holsboer, F.

Publication type:

Article

Mean 14.00-17.00 h plasma cortisol concentration and its relationship to the 1 mg-dexamethasone suppression response in depressives and controls.

Published in:

Acta Psychiatrica Scandinavica, 1984, v. 69, n. 5, p. 383, doi. 10.1111/j.1600-0447.1984.tb02509.x

By:

Holsboer, F.;
Gerken, A.;
Steiger, A.;
Fass, V.

Publication type:

Article

Effect of Sulpiride in Endogenous Depression.

Published in:

Acta Psychiatrica Scandinavica, 1984, v. 69, p. 43, doi. 10.1111/j.1600-0447.1984.tb06858.x

By:

Benkert, O.;
Holsboer, F.

Publication type:

Article

Dexamethasone suppression of 11-deoxycorticosterone, corticosterone and cortisol in depressed female patients and normal controls.

Published in:

Acta Psychiatrica Scandinavica, 1982, v. 66, n. 1, p. 18, doi. 10.1111/j.1600-0447.1982.tb00910.x

By:

Holsboer, F.;
Doerr, H. G.;
Sippell, W. G.

Publication type:

Article

Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice.

Published in:

Journal of Psychopharmacology, 2010, v. 24, n. 5, p. 733, doi. 10.1177/0269881109103091

By:

Thoeringer, C. K.;
Erhardt, A.;
Sillaber, I.;
Mueller, M. B.;
Ohl, F.;
Holsboer, F.;
Keck, M. E.

Publication type:

Article