Works matching AU Holman, Rury R.

Results: 162

Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5: A Systematic Review and Meta-analysis.

Published in:

2017

By:

Malhotra, Rakesh;
Nguyen, Hoang Anh;
Benavente, Oscar;
Mete, Mihriye;
Howard, Barbara V.;
Mant, Jonathan;
Odden, Michelle C.;
Peralta, Carmen A.;
Cheung, Alfred K.;
Nadkarni, Girish N.;
Coleman, Ruth L.;
Holman, Rury R.;
Zanchetti, Alberto;
Peters, Ruth;
Beckett, Nigel;
Staessen, Jan A.;
H. Ix, Joachim;
Ix, Joachim H

Publication type:

journal article

Estimating risk factor progression equations for the UKPDS Outcomes Model 2 (UKPDS 90).

Published in:

Diabetic Medicine, 2021, v. 38, n. 10, p. 1, doi. 10.1111/dme.14656

By:

Leal, Jose;
Alva, Maria;
Gregory, Vanessa;
Hayes, Alison;
Mihaylova, Borislava;
Gray, Alastair M.;
Holman, Rury R.;
Clarke, Philip

Publication type:

Article

Predicting major adverse limb events in individuals with type 2 diabetes: Insights from the EXSCEL trial.

Published in:

Diabetic Medicine, 2021, v. 38, n. 10, p. 1, doi. 10.1111/dme.14552

By:

Weissler, E. Hope;
Clare, Robert M.;
Lokhnygina, Yuliya;
Buse, John B.;
Goodman, Shaun G.;
Katona, Brian;
Iqbal, Nayyar;
Pagidipati, Neha J.;
Sattar, Naveed;
Holman, Rury R.;
Hernandez, Adrian F.;
Mentz, Robert J.;
Patel, Manesh R.;
Jones, W. Schuyler

Publication type:

Article

Using QALYs as an Outcome for Assessing Global Prediction Accuracy in Diabetes Simulation Models.

Published in:

Medical Decision Making, 2025, v. 45, n. 1, p. 45, doi. 10.1177/0272989X241285866

By:

Dakin, Helen A.;
Gao, Ni;
Leal, José;
Holman, Rury R.;
Tran-Duy, An;
Clarke, Philip

Publication type:

Article

Accurately Reflecting Uncertainty When Using Patient-Level Simulation Models to Extrapolate Clinical Trial Data.

Published in:

Medical Decision Making, 2020, v. 40, n. 4, p. 460, doi. 10.1177/0272989X20916442

By:

Dakin, Helen A.;
Leal, José;
Briggs, Andrew;
Clarke, Philip;
Holman, Rury R.;
Gray, Alastair

Publication type:

Article

Life Expectancy in Individuals With Type 2 Diabetes: Implications for Annuities.

Published in:

Medical Decision Making, 2010, v. 30, n. 3, p. 409, doi. 10.1177/0272989X09349960

By:

Price, Hermione C.;
Clarke, Philip M.;
Gray, Alastair M.;
Holman, Rury R.

Publication type:

Article

UKPDS 20: Plasma Leptin, Obesity, and Plasma Insulin in Type 2 Diabetic Subjects.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 2, p. 654, doi. 10.1210/jcem.82.2.3744

By:

WIDJAJA, ADJI;
STRATTON, IRENE M.;
HORN, RUEDIGER;
HOLMAN, RURY R.;
TURNER, ROBERT;
BRABANT, GEORG

Publication type:

Article

The impact of individualised cardiovascular disease (CVD) risk estimates and lifestyle advice on physical activity in individuals at high risk of CVD: a pilot 2 x 2 factorial understanding risk trial.

Published in:

Cardiovascular Diabetology, 2008, v. 7, p. 1, doi. 10.1186/1475-2840-7-21

By:

Price, Hermione C.;
Tucker, Lynne;
Griffin, Simon J.;
Holman, Rury R.

Publication type:

Article

Long-term glucose variability and risk of nephropathy complication in UKPDS, ACCORD and VADT trials.

Published in:

Diabetologia, 2020, v. 63, n. 11, p. 2482, doi. 10.1007/s00125-020-05273-7

By:

Zhou, Jin J.;
Coleman, Ruth;
Holman, Rury R.;
Reaven, Peter

Publication type:

Article

Metformin and Risk of Cardiovascular Disease.

Published in:

Cardiology, 1999, v. 91, n. 3, p. 203, doi. 10.1159/000006910

By:

Turner, Robert C.;
Holman, Rury R.

Publication type:

Article

Estimated glomerular filtration rate slope and risk of primary and secondary major adverse cardiovascular events and heart failure hospitalization in people with type 2 diabetes: An analysis of the EXSCEL trial.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 10, p. 4602, doi. 10.1111/dom.15817

By:

Oulhaj, Abderrahim;
Aziz, Faisal;
Suliman, Abubaker;
Eller, Kathrin;
Bentoumi, Rachid;
Buse, John B.;
Al Mahmeed, Wael;
von Lewinski, Dirk;
Coleman, Ruth L.;
Holman, Rury R.;
Sourij, Harald

Publication type:

Article

Sex differences in the complications, care and clinical outcomes of patients with type 2 diabetes in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 6, p. 1473, doi. 10.1111/dom.14993

By:

Green, Jennifer B.;
Merrill, Peter;
Lokhnygina, Yuliya;
Mentz, Robert J.;
Alfredsson, Joakim;
Holman, Rury R.

Publication type:

Article

Impact of baseline kidney function on the effects of sodium‐glucose co‐transporter‐2 inhibitors on kidney and heart failure outcomes: A systematic review and meta‐analysis of randomized controlled trials.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 5, p. 1341, doi. 10.1111/dom.14986

By:

Maddaloni, Ernesto;
Cavallari, Ilaria;
La Porta, Ylenia;
Appetecchia, Alessandro;
D'Onofrio, Luca;
Grigioni, Francesco;
Buzzetti, Raffaella;
Holman, Rury R.

Publication type:

Article

Joint longitudinal and time‐to‐event modelling compared with standard Cox modelling in patients with type 2 diabetes with and without established cardiovascular disease: An analysis of the EXSCEL trial.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 5, p. 1261, doi. 10.1111/dom.14975

By:

Oulhaj, Abderrahim;
Aziz, Faisal;
Suliman, Abubaker;
Iqbal, Nayyar;
Coleman, Ruth L.;
Holman, Rury R.;
Sourij, Harald

Publication type:

Article

Cardiovascular and renal safety of metformin in patients with diabetes and moderate or severe chronic kidney disease: Observations from the EXSCEL and SAVOR‐TIMI 53 cardiovascular outcomes trials.

Published in:

Diabetes, Obesity & Metabolism, 2021, v. 23, n. 5, p. 1101, doi. 10.1111/dom.14313

By:

Clegg, Lindsay E.;
Jing, Yankang;
Penland, Robert C.;
Boulton, David W.;
Hernandez, Adrian F.;
Holman, Rury R.;
Vora, Jiten

Publication type:

Article

Effect of once‐weekly exenatide on estimated glomerular filtration rate slope depends on baseline renal risk: A post hoc analysis of the EXSCEL trial.

Published in:

Diabetes, Obesity & Metabolism, 2020, v. 22, n. 12, p. 2493, doi. 10.1111/dom.14175

By:

van der Aart‐van der Beek, Annemarie B.;
Clegg, Lindsay E.;
Penland, Robert C.;
Boulton, David W.;
Sjöström, C. David;
Mentz, Robert J.;
Holman, Rury R.;
Heerspink, Hiddo J. L.

Publication type:

Article

Can the cardiovascular risk reductions observed with empagliflozin in the EMPA‐REG OUTCOME trial be explained by concomitant changes seen in conventional cardiovascular risk factor levels?

Published in:

Diabetes, Obesity & Metabolism, 2020, v. 22, n. 7, p. 1151, doi. 10.1111/dom.14017

By:

Coleman, Ruth L.;
Gray, Alastair M.;
Broedl MD, Uli C.;
Fitchett, David;
George, Jyothis T.;
Woerle, Hans J.;
Zinman, Bernard;
Holman, Rury R.

Publication type:

Article

Prediction and validation of exenatide risk marker effects on progression of renal disease: Insights from EXSCEL.

Published in:

Diabetes, Obesity & Metabolism, 2020, v. 22, n. 5, p. 798, doi. 10.1111/dom.13958

By:

Idzerda, Nienke M. A.;
Clegg, Lindsay E.;
Hernandez, Adrian F.;
Bakris, George;
Penland, Robert C.;
Boulton, David W.;
Bethel, M. Angelyn;
Holman, Rury R.;
Heerspink, Hiddo J. L.

Publication type:

Article

Long‐term risk of cardiovascular disease in individuals with latent autoimmune diabetes in adults (UKPDS 85).

Published in:

Diabetes, Obesity & Metabolism, 2019, v. 21, n. 9, p. 2115, doi. 10.1111/dom.13788

By:

Maddaloni, Ernesto;
Coleman, Ruth L.;
Pozzilli, Paolo;
Holman, Rury R.

Publication type:

Article

Time trends in prescribing of type 2 diabetes drugs, glycaemic response and risk factors: A retrospective analysis of primary care data, 2010–2017.

Published in:

Diabetes, Obesity & Metabolism, 2019, v. 21, n. 7, p. 1576, doi. 10.1111/dom.13687

By:

Dennis, John M.;
Henley, William E.;
McGovern, Andrew P.;
Hattersley, Andrew T.;
Shields, Beverley M.;
Jones, Angus G.;
Farmer, Andrew J.;
Sattar, Naveed;
Holman, Rury R.;
Pearson, Ewan R.

Publication type:

Article

The UK Prospective Diabetes Study.

Published in:

Annals of Medicine, 1996, v. 28, n. 5, p. 439, doi. 10.3109/07853899608999105

By:

Turner, Robert C.;
Holman, Rury R.

Publication type:

Article

Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes.

Published in:

Diabetologia, 2024, v. 67, n. 5, p. 822, doi. 10.1007/s00125-024-06099-3

By:

Cardoso, Pedro;
Young, Katie G.;
Nair, Anand T. N.;
Hopkins, Rhian;
McGovern, Andrew P.;
Haider, Eram;
Karunaratne, Piyumanga;
Donnelly, Louise;
Mateen, Bilal A.;
Sattar, Naveed;
Holman, Rury R.;
Bowden, Jack;
Hattersley, Andrew T.;
Pearson, Ewan R.;
Jones, Angus G.;
Shields, Beverley M.;
McKinley, Trevelyan J.;
Dennis, John M.

Publication type:

Article

Design and rationale of the EMPA‐VISION trial: investigating the metabolic effects of empagliflozin in patients with heart failure.

Published in:

ESC Heart Failure, 2021, v. 8, n. 4, p. 2580, doi. 10.1002/ehf2.13406

By:

Hundertmark, Moritz J.;
Agbaje, Olorunsola F.;
Coleman, Ruth;
George, Jyothis T.;
Grempler, Rolf;
Holman, Rury R.;
Lamlum, Hanan;
Lee, Jisoo;
Milton, Joanne E.;
Niessen, Heiko G.;
Rider, Oliver;
Rodgers, Christopher T.;
Valkovič, Ladislav;
Wicks, Eleanor;
Mahmod, Masliza;
Neubauer, Stefan

Publication type:

Article

An outcome model approach to transporting a randomized controlled trial results to a target population.

Published in:

2019

By:

Goldstein, Benjamin A;
Phelan, Matthew;
Pagidipati, Neha J;
Holman, Rury R;
Pencina, Michael J;
Stuart, Elizabeth A

Publication type:

journal article

Use of focus groups to develop methods to communicate cardiovascular disease risk and potential for risk reduction to people with type 2 diabetes.

Published in:

Family Practice, 2009, v. 26, n. 5, p. 351, doi. 10.1093/fampra/cmp041

By:

Price, Hermione C.;
Dudley, Christina;
Barrow, Beryl;
Kennedy, Ian;
Griffin, Simon J.;
Holman, Rury R.

Publication type:

Article

Estimating Risk Factor Time Paths Among People with Type 2 Diabetes and QALY Gains from Risk Factor Management.

Published in:

PharmacoEconomics, 2024, v. 42, n. 9, p. 1017, doi. 10.1007/s40273-024-01398-4

By:

Gao, Ni;
Dakin, Helen A.;
Holman, Rury R.;
Lim, Lee-Ling;
Leal, José;
Clarke, Philip

Publication type:

Article

A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk.

Published in:

Science Translational Medicine, 2022, v. 14, n. 639, p. 1, doi. 10.1126/scitranslmed.abj9625

By:

Williams, Stephen A.;
Ostroff, Rachel;
Hinterberg, Michael A.;
Coresh, Josef;
Ballantyne, Christie M.;
Matsushita, Kunihiro;
Mueller, Christian E.;
Walter, Joan;
Jonasson, Christian;
Holman, Rury R.;
Shah, Svati H.;
Sattar, Naveed;
Taylor, Roy;
Lean, Michael E.;
Kato, Shintaro;
Shimokawa, Hiroaki;
Sakata, Yasuhiko;
Nochioka, Kotaro;
Parikh, Chirag R.;
Coca, Steven G.

Publication type:

Article

Comparison of nine platelet function tests used to determine responses to different aspirin dosages in people with type 2 diabetes.

Published in:

Platelets, 2019, v. 30, n. 4, p. 521, doi. 10.1080/09537104.2018.1478402

By:

Harrison, Paul;
Bethel, M. Angelyn;
Kennedy, Irene;
Dinsdale, Robert;
Coleman, Ruth;
Holman, Rury R.

Publication type:

Article

Comparison of medical resources and costs among patients with coronary heart disease and impaired glucose tolerance in the Acarbose Cardiovascular Evaluation trial.

Published in:

Journal of Diabetes, 2024, v. 16, n. 2, p. 1, doi. 10.1111/1753-0407.13473

By:

Morrow, Liam Mc;
Becker, Frauke;
Coleman, Ruth L.;
Gerstein, Hertzel C.;
Rydén, Lars;
Schöder, Stefan;
Gray, Alastair M.;
Leal, Jose;
Holman, Rury R.

Publication type:

Article

Health utilities in Chinese patients with coronary heart disease and impaired glucose tolerance (ACE): A longitudinal analysis of a randomized, double‐blind, placebo‐controlled trial.

Published in:

Journal of Diabetes, 2022, v. 14, n. 7, p. 455, doi. 10.1111/1753-0407.13294

By:

Leal, José;
Becker, Frauke;
Lim, Lee‐Ling;
Holman, Rury R.;
Gray, Alastair M.

Publication type:

Article

Predicting the risk of developing type 2 diabetes in Chinese people who have coronary heart disease and impaired glucose tolerance.

Published in:

Journal of Diabetes, 2021, v. 13, n. 10, p. 817, doi. 10.1111/1753-0407.13175

By:

Xu, Shishi;
Scott, Charles A.B.;
Coleman, Ruth L.;
Tuomilehto, Jaakko;
Holman, Rury R.

Publication type:

Article

What does the Acarbose Cardiovascular Evaluation (ACE) trial tell us?

Published in:

Journal of Diabetes, 2018, v. 10, n. 8, p. 683, doi. 10.1111/1753-0407.12770

By:

Holman, Rury R.

Publication type:

Article

A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes.

Published in:

2002

By:

Viberti, Giancarlo;
Kahn, Steven E;
Greene, Douglas A;
Herman, William H;
Zinman, Bernard;
Holman, Rury R;
Haffner, Steven M;
Levy, Daniel;
Lachin, John M;
Berry, Rhona A;
Heise, Mark A;
Jones, Nigel P;
Freed, Martin I

Publication type:

journal article

A Diabetes Outcome Progression Trial (ADOPT).

Published in:

Diabetes Care, 2002, v. 25, n. 10, p. 1737, doi. 10.2337/diacare.25.10.1737

By:

Viberti, Giancarlo;
Kahn, Steven E.;
Greene, Douglas A.;
Herman, William H.;
Zinman, Bernard;
Holman, Rury R.;
Haffner, Steven M.;
Levy, Daniel;
Lachin, John M.;
Berry, Rhona A.;
Heise, Mark A.;
Jones, Nigel P.;
Freed, Martin I.

Publication type:

Article

Are lower fasting plasma glucose levels at diagnosis of type 2 diabetes associated with improved outcomes?: U.K. prospective diabetes study 61.

Published in:

2002

By:

Colagiuri, Stephen;
Cull, Carole A.;
Holman, Rury R.;
UKPDS Group

Publication type:

journal article

UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes.

Published in:

2002

By:

Adler, Amanda I.;
Stevens, Richard J.;
Stratton, Irene M.;
Holman, Rury R.;
Neil, Andrew;
Boulton, Andrew J. M.

Publication type:

journal article

Sulfonylurea inadequacy: efficacy of addition of insulin over 6 years in patients with type 2 diabetes in the U.K. Prospective Diabetes Study (UKPDS 57).

Published in:

2002

By:

Wright, Alex;
Burden, A C Felix;
Paisey, Richard B;
Cull, Carole A;
Holman, Rury R;
U.K. Prospective Diabetes Study Group

Publication type:

journal article

Sulfonylurea Inadequacy.

Published in:

Diabetes Care, 2002, v. 25, n. 2, p. 330

By:

Wright, Alex;
Burden, A.C. Felix;
Paisey, Richard B.;
Cull, Cariole A.;
Holman, Rury R.

Publication type:

Article

Relationship between ethnicity and glycemic control, lipid profiles, and blood pressure during the first 9 years of type 2 diabetes: U.K. Prospective Diabetes Study (UKPDS 55).

Published in:

2001

By:

Davis, Timothy M. E.;
Cull, Carole A.;
Holman, Rury R.;
Davis, T M;
Cull, C A;
Holman, R R;
U.K. Prospective Diabetes Study (UKPDS) Group

Publication type:

journal article

Does the Choice of Treatment for Type 2 Diabetes Affect the Physiological Response to Hypoglycemia?

Published in:

Diabetes Care, 2000, v. 23, n. 7, p. 1022, doi. 10.2337/diacare.23.7.1022

By:

PEACEY, STEPHEN R.;
ROBINSON, ROBERT;
BEDFORD, CAROLINE;
HARRIS, NIGEL D.;
MACDONALD, IAN A.;
HOLMAN, RURY R.;
HELLER, SIMON R.

Publication type:

Article

A Randomized Double-Blind Trial of Acarbose in Type 2 Diabetes Shows Improved Glycemic Control Over 3 Years (U.K. Prospective Diabetes Study 44).

Published in:

Diabetes Care, 1999, v. 22, n. 6, p. 960, doi. 10.2337/diacare.22.6.960

By:

Holman, Rury R.;
Cull, Girdle A.;
Turner, Robert C.

Publication type:

Article

Changes in Amylin and Amylin-Like Peptide Concentrations and β-Cell Function in Response to Sulfonylurea or Insulin Therapy in NIDDM.

Published in:

Diabetes Care, 1998, v. 21, n. 5, p. 810, doi. 10.2337/diacare.21.5.810

By:

Rachman, Jonathan;
Payne, Martin J.;
Levy, Jonathan C.;
Barrow, Beryl A.;
Holman, Rury R.;
Turner, Robert C.

Publication type:

Article

U.K. Prospective Diabetes Study 22.

Published in:

Diabetes Care, 1997, v. 20, n. 9, p. 1435, doi. 10.2337/diacare.20.9.1435

By:

Davis, Timothy M. E.;
Stratton, Irene M.;
Fox, Charles J.;
Holman, Rury R.;
Turner, Robert C.

Publication type:

Article

U.K. Prospective Diabetes Study.

Published in:

Diabetes Care, 1996, v. 19, n. 2, p. 182, doi. 10.2337/diacare.19.2.182

By:

Turner, Robert C.;
Cull, Carole A.;
Holman, Rury R.

Publication type:

Article

Insulin Use in NIDDM.

Published in:

Diabetes Care, 1990, v. 13, n. 9, p. 1011, doi. 10.2337/diacare.13.9.1011

By:

Turner, Robert C.;
Holman, Rury R.

Publication type:

Article

Introduction.

Published in:

Diabetic Medicine, 2008, v. 25, p. 1, doi. 10.1111/j.1464-5491.2008.02539.x

By:

Holman, Rury R.;
Watkins, Peter J.

Publication type:

Article

Effects of Intensive Blood Pressure Treatment on Orthostatic Hypotension : A Systematic Review and Individual Participant-based Meta-analysis.

Published in:

2021

By:

Juraschek, Stephen P.;
Hu, Jiun-Ruey;
Cluett, Jennifer L.;
Ishak, Anthony;
Mita, Carol;
Lipsitz, Lewis A.;
Appel, Lawrence J.;
Beckett, Nigel S.;
Coleman, Ruth L.;
Cushman, William C.;
Davis, Barry R.;
Grandits, Greg;
Holman, Rury R.;
Miller III, Edgar R.;
Peters, Ruth;
Staessen, Jan A.;
Taylor, Addison A.;
Thijs, Lutgarde;
Wright Jr., Jackson T.;
Mukamal, Kenneth J.

Publication type:

journal article

Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17556-z

By:

Baggio, Laurie L.;
Varin, Elodie M.;
Koehler, Jacqueline A.;
Cao, Xiemin;
Lokhnygina, Yuliya;
Stevens, Susanna R.;
Holman, Rury R.;
Drucker, Daniel J.

Publication type:

Article

Response to Comments on Maddaloni et al. Osteoprotegerin, Osteopontin, and Osteocalcin Are Associated With Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL. Diabetes Care 2025;48:235–242.

Published in:

2025

By:

Maddaloni, Ernesto;
Nguyen, Maggie;
Shah, Svati H.;
Holman, Rury R.

Publication type:

Letter

Osteoprotegerin, Osteopontin, and Osteocalcin Are Associated With Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL.

Published in:

Diabetes Care, 2025, v. 48, n. 2, p. 235, doi. 10.2337/dc24-1455

By:

Maddaloni, Ernesto;
Nguyen, Maggie;
Shah, Svati H.;
Holman, Rury R.

Publication type:

Article