Works by Holly, Jeff

Results: 92

The relation between adiposity throughout the life course and variation in IGFs and IGFBPs: evidence from the ProtecT (Prostate testing for cancer and Treatment) study.

Published in:

2010

By:

Rowlands, Mari-Anne;
Holly, Jeff;
Gunnell, David;
Gilbert, Rebecca;
Donovan, Jenny;
Lane, J.;
Marsden, Gemma;
Collin, Simon;
Hamdy, Freddie;
Neal, David;
Martin, Richard;
Holly, Jeff M P;
Lane, J Athene;
Collin, Simon M;
Neal, David E;
Martin, Richard M

Publication type:

journal article

Childhood stature and adult cancer risk: the Boyd Orr cohort.

Published in:

2009

By:

Whitley, Elise;
Martin, Richard;
Davey Smith, George;
Holly, Jeff;
Gunnell, David;
Martin, Richard M;
Smith, George Davey;
Holly, Jeff M P

Publication type:

journal article

The Insulin-Like Growth Factor (IGF) Family and Breast Cancer.

Published in:

Breast Disease, 2003, v. 18, n. 1, p. 45, doi. 10.3233/BD-2003-18106

By:

Perks, Claire M.;
Holly, Jeff M. P.

Publication type:

Article

IGFBPs and Breast Cancer.

Published in:

Breast Disease, 2003, v. 17, n. 1, p. 91, doi. 10.3233/BD-2003-17109

By:

Perks, Claire M.;
Holly, Jeff M. P.

Publication type:

Article

Influence of treatment with tamoxifen and change in tumor burden on the IGF-system in breast cancer patients.

Published in:

International Journal of Cancer, 1996, v. 69, n. 4, p. 335, doi. 10.1002/(SICI)1097-0215(19960822)69:4<335::AID-IJC17>3.0.CO;2-4

By:

Helle, Svein I.;
Holly, Jeff M. P.;
Tally, Michael;
Hall, Kerstin;
Stappes, Jos Van Der;
Lonning, Per E.

Publication type:

Article

A Single-arm Phase II Trial of Neoadjuvant Cabazitaxel and Cisplatin Chemotherapy for Muscle-Invasive Transitional Cell Carcinoma of the Urinary Bladder.

Published in:

Clinical Genitourinary Cancer, 2021, v. 19, n. 4, p. 325, doi. 10.1016/j.clgc.2021.02.001

By:

Challapalli, Amarnath;
Masson, Susan;
White, Paul;
Dailami, Narges;
Pearson, Sylvia;
Rowe, Edward;
Koupparis, Anthony;
Oxley, Jon;
Abdelaziz, Ahmed;
Ash-Miles, Janice;
Bravo, Alicia;
Foulstone, Emily;
Perks, Claire;
Holly, Jeff;
Persad, Raj;
Bahl, Amit

Publication type:

Article

Associations of Insulin-Like Growth Factor (IGF)-I, IGFII, IGF Binding Protein (IGFBP)-2 and IGFBP-3 with Ultrasound Measures of Atherosclerosis and Plaque Stability in an Older Adult Population.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2008, v. 93, n. 4, p. 1331, doi. 10.1210/jc.2007-2295

By:

Martin, Richard M.;
Gunnell, David;
Whitley, Elise;
Nicolaides, Andrew;
Griffin, Maura;
Georgiou, Niki;
Smith, George Davey;
Ebrahim, Shah;
Holly, Jeff M. P.

Publication type:

Article

Associations of Adiposity from Childhood into Adulthood with Insulin Resistance and the Insulin-Like Growth Factor System: 65-Year Follow-Up of the Boyd Orr Cohort.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 9, p. 3287, doi. 10.1210/jc.2006-0745

By:

Martin, Richard M.;
Holly, Jeff M. P.;
Smith, George Davey;
Gunnell, David

Publication type:

Article

Timing of puberty determines serum insulin-like growth factor-I in late adulthood.

Published in:

2006

By:

Sandhu, Jat;
Davey Smith, George;
Holly, Jeff;
Cole, Tim J;
Ben-Shlomo, Yoav

Publication type:

journal article

Insulin-like growth factor-I and growth in height, leg length, and trunk length between ages 5 and 10 years.

Published in:

2006

By:

Rogers, Imogen;
Metcalfe, Chris;
Gunnell, David;
Emmett, Pauline;
Dunger, David;
Holly, Jeff;
Avon Longitudinal Study of Parents Children Study Team

Publication type:

journal article

Associations of Childhood and Adulthood Height and the Components of Height with Insulin-Like Growth Factor Levels in Adulthood: A 65-Year Follow-Up of the Boyd Orr Cohort.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 4, p. 1382, doi. 10.1210/jc.2005-1722

By:

Bray, Isabelle;
Gunnell, David;
Holly, Jeff M. P.;
Middleton, Nicos;
Smith, George Davey;
Martin, Richard M.

Publication type:

Article

Mature Subcutaneous and Visceral Adipocyte Concentrations of Adiponectin Are Highly Correlated in Prepubertal Children and Inversely Related to Body Mass Index Standard Deviation Score.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 1, p. 332, doi. 10.1210/jc.2005-1571

By:

Sabin, Matthew A.;
Holly, Jeff M. P.;
Shield, Julian P. H.;
Turner, Stephen J.;
Grohmann, Malcolm J.;
Stewart, Claire E. H.;
Crowne, Elizabeth C.

Publication type:

Article

Regulation of the Somatotropic Axis by Intensive Insulin Therapy during Protracted Critical Illness.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 7, p. 3105, doi. 10.1210/jc.2003-032102

By:

MESOTTEN, DIETER;
WOUTERS, PIETER J.;
PEETERS, ROBIN P.;
HARDMAN, KEVIN V.;
HOLLY, JEFF M.;
BAXTER, ROBERT C.;
VAN DEN BERGHE, GREET

Publication type:

Article

Changes in the Local Regulation of Insulin-Like Growth Factors I and II and Insulin-Like Growth Factor-Binding Proteins in Osteoarthritis of the Canine Stifle Joint Secondary to Cruciate Ligament Rupture.

Published in:

Veterinary Surgery, 2003, v. 32, n. 4, p. 313, doi. 10.1053/jvet.2003.50037

By:

Fernihough, Janet K.;
Innes, John F.;
Billingham, Michael E. J.;
Holly, Jeff M. P.

Publication type:

Article

IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.

Published in:

Diabetologia, 2021, v. 64, n. 7, p. 1690, doi. 10.1007/s00125-021-05427-1

By:

Lay, Abigail C.;
Hale, Lorna J.;
Stowell-Connolly, Holly;
Pope, Robert J. P.;
Nair, Viji;
Ju, Wenjun;
Marquez, Eva;
Rollason, Ruth;
Hurcombe, Jenny A.;
Hayes, Bryony;
Roberts, Timothy;
Gillam, Lawrence;
Allington, Jonathan;
Nelson, Robert G.;
Kretzler, Matthias;
Holly, Jeff M. P.;
Perks, Claire M.;
McArdle, Craig A.;
Welsh, Gavin I.;
Coward, Richard J. M.

Publication type:

Article

The Neglected Insulin: IGF-II, a Metabolic Regulator with Implications for Diabetes, Obesity, and Cancer.

Published in:

Cells (2073-4409), 2019, v. 8, n. 10, p. 1207, doi. 10.3390/cells8101207

By:

Holly, Jeff M. P.;
Biernacka, Kalina;
Perks, Claire M.

Publication type:

Article

Developing multi-target therapeutics to fine-tune the evolutionary dynamics of the cancer ecosystem.

Published in:

2015

By:

Lei Xie;
Bourne, Philip E.;
Masaaki Murakami;
Holly, Jeff M. P.

Publication type:

Opinion

Effects of Nutritional Supplementation during Pregnancy on Early Adult Disease Risk: Follow Up of Offspring of Participants in a Randomised Controlled Trial Investigating Effects of Supplementation on Infant Birth Weight.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083371

By:

Macleod, John;
Tang, Lie;
Hobbs, F. D. Richard;
Wharton, Brian;
Holder, Roger;
Hussain, Shakir;
Nichols, Linda;
Stewart, Paul;
Clark, Penny;
Luzio, Steve;
Holly, Jeff;
Davey Smith, George

Publication type:

Article

Associations of Insulin and Insulin-Like Growth Factors with Physical Performance in Old Age in the Boyd Orr and Caerphilly Studies.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030096

By:

Birnie, Kate;
Ben-Shlomo, Yoav;
Holly, Jeff M. P.;
Gunnell, David;
Ebrahim, Shah;
Bayer, Antony;
Gallacher, John;
Martin, Richard M.

Publication type:

Article

A putative functional polymorphism in the IGF-I gene: association studies with type 2 diabetes, adult height, glucose tolerance, and fetal growth in U.K. populations.

Published in:

2002

By:

Frayling, Timothy M;
Hattersley, Andrew T;
McCarthy, Anne;
Holly, Jeff;
Mitchell, Simon M S;
Gloyn, Anna L;
Owen, Katharine;
Davies, David;
Smith, George Davey;
Ben-Shlomo, Yoav

Publication type:

journal article

A Putative Functional Polymorphism in the IGF-I Gene.

Published in:

Diabetes, 2002, v. 51, n. 7, p. 2313, doi. 10.2337/diabetes.51.7.2313

By:

Frayling, Timothy M.;
Hattersley, Andrew T.;
McCarthy, Anne;
Holly, Jeff;
Mitchell, Simon M.S.;
Gloyn, Anna L.;
Owen, Katharine;
Davies, David;
Davey Smith, George;
Ben-Shlomo, Yoav

Publication type:

Article

Epithelial-to-mesenchymal transition in breast cancer: a role for insulin-like growth factor I and insulin-like growth factor-binding protein 3?

Published in:

Breast Cancer: Targets & Therapy, 2015, v. 7, p. 9, doi. 10.2147/BCTT.S43932

By:

Zielinska, Hanna A.;
Bahl, Amit;
Holly, Jeff MP;
Perks, Claire M.

Publication type:

Article

Childhood milk consumption is associated with better physical performance in old age.

Published in:

Age & Ageing, 2012, v. 41, n. 6, p. 776, doi. 10.1093/ageing/afs052

By:

Birnie, Kate;
Ben-Shlomo, Yoav;
Gunnell, David;
Ebrahim, Shah;
Bayer, Antony;
Gallacher, John;
Holly, Jeff M. P.;
Martin, Richard M.

Publication type:

Article

Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations.

Published in:

European Journal of Endocrinology, 2016, v. 174, n. 6, p. C1, doi. 10.1530/eje-16-0111

By:

Christiansen, Jens Sandahl;
Backeljauw, Philippe F.;
Bidlingmaier, Martin;
Biller, Beverly M. K.;
Boguszewski, Margaret C. S.;
Casanueva, Felipe F.;
Chanson, Philippe;
Chatelain, Pierre;
Choong, Catherine S.;
Clemmons, David R.;
Cohen, Laurie E.;
Cohen, Pinchas;
Frystyk, Jan;
Grimberg, Adda;
Yukihiro Hasegawa;
Haymond, Morey W.;
Ken Ho;
Hoffman, Andrew R.;
Holly, Jeff M. P.;
Reiko Horikawa

Publication type:

Article

Differential IGF-independent effects of insulin-like growth factor binding proteins (1-6) on apoptosis of breast epithelial cells.

Published in:

Journal of Cellular Biochemistry, 1999, v. 75, n. 4, p. 652, doi. 10.1002/(SICI)1097-4644(19991215)75:4<652::AID-JCB11>3.0.CO;2-0

By:

Perks, Claire M.;
Bowen, Samantha;
Gill, Zahidah P.;
Newcomb, Paul V.;
Holly, Jeff M.P.

Publication type:

Article

Circulating insulin-like growth factor peptides and prostate cancer risk: A systematic review and meta-analysis.

Published in:

International Journal of Cancer, 2009, v. 124, n. 10, p. 2416, doi. 10.1002/ijc.24202

By:

Rowlands, Mari-Anne;
Gunnell, David;
Harris, Ross;
Vatten, Lars J.;
Holly, Jeff M.P.;
Martin, Richard M.

Publication type:

Article

Systemic IGF-I administration stimulates the in vivo growth of early, but not advanced, renal cell carcinoma.

Published in:

International Journal of Cancer, 2008, v. 123, n. 6, p. 1286, doi. 10.1002/ijc.23642

By:

Rosendahl, Ann H.;
Holly, Jeff M.P.;
Celander, Mona;
Forsberg, Göran

Publication type:

Article

Commentary: A Machine-Generated View of the Role of Blood Glucose Levels in the Severity of COVID-19. A Metabolic Endocrinology Perspective.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.877973

By:

Holly, Jeff M. P.

Publication type:

Article

Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men.

Published in:

PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0187741

By:

Watts, Eleanor L.;
Appleby, Paul N.;
Albanes, Demetrius;
Black, Amanda;
Chan, June M.;
Chen, Chu;
Cirillo, Piera M.;
Cohn, Barbara A.;
Cook, Michael B.;
Donovan, Jenny L.;
Ferrucci, Luigi;
Garland, Cedric F.;
Giles, Graham G.;
Goodman, Phyllis J.;
Habel, Laurel A.;
Haiman, Christopher A.;
Holly, Jeff M. P.;
Hoover, Robert N.;
Kaaks, Rudolf;
Knekt, Paul

Publication type:

Article

Loss of PTEN Expression Is Associated With IGFBP2 Expression, Younger Age, and Late Stage in Triple-Negative Breast Cancer.

Published in:

American Journal of Clinical Pathology, 2014, v. 141, n. 3, p. 323, doi. 10.1309/AJCPR11DEAYPTUSL

By:

Dean, Sarah J. R.;
Perks, Claire M.;
Holly, Jeff M. P.;
Bhoo-Pathy, Nirmala;
Lai-Meng Looi;
Taib Mohammed, Nur Aishah;
Koobotse, Moses O.;
Soo-Hwang Teo;
Kein-Seong Mun;
Cheng-Har Yip;
Rhodes, Anthony

Publication type:

Article

Milk as a food for growth? The insulin-like growth factors link.

Published in:

2006

By:

Rogers I;
Emmett P;
Gunnell D;
Dunger D;
Holly J;
ALSPAC Study Tteam;
Rogers, Imogen;
Emmett, Pauline;
Gunnell, David;
Dunger, David;
Holly, Jeff

Publication type:

journal article

Milk as a food for growth? The insulin-like growth factors link.

Published in:

Public Health Nutrition, 2006, v. 9, n. 3, p. 359

By:

Imogen Rogers;
Pauline Emmett;
David Gunnell;
David Dunger;
Jeff Holly

Publication type:

Article

IGF Binding Proteins (IGFBPs) and Regulation of Breast Cancer Biology.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2008, v. 13, n. 4, p. 455, doi. 10.1007/s10911-008-9106-4

By:

Claire Perks;
Jeff Holly

Publication type:

Article

Circulating adiponectin and leptin and risk of overall and aggressive prostate cancer: a systematic review and meta-analysis.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79345-4

By:

Burton, Anya J.;
Gilbert, Rebecca;
Tilling, Kate;
Langdon, Ryan;
Donovan, Jenny L.;
Holly, Jeff M. P.;
Martin, Richard M.

Publication type:

Article

Identification of genetic variants that influence circulating IGF1 levels: a targeted search strategy.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 10, p. 1457, doi. 10.1093/hmg/ddn034

By:

Palles, Claire;
Johnson, Nichola;
Coupland, Ben;
Taylor, Claire;
Carvajal, Jaime;
Holly, Jeff;
Fentiman, Ian S.;
dos Santos Silva, Isabel;
Ashworth, Alan;
Peto, Julian;
Fletcher, Olivia

Publication type:

Article

Current understanding of circulating tumor cells - potential value in malignancies of the central nervous system.

Published in:

Frontiers in Neurology, 2015, p. 1, doi. 10.3389/fneur.2015.00174

By:

Adamczyk, Lukasz A.;
Williams, Hannah;
Ellis, Hayley Patricia;
Haynes, Harry R.;
Kurian, Kathreena M.;
Frankow, Aleksandra;
Perks, Claire;
Holly, Jeff M. P.

Publication type:

Article

Systemic Metabolism, Its Regulators, and Cancer: Past Mistakes and Future Potential.

Published in:

Frontiers in Endocrinology, 2019, p. N.PAG, doi. 10.3389/fendo.2019.00065

By:

Holly, Jeff M. P.;
Biernacka, Kalina;
Perks, Claire M.

Publication type:

Article

Hyperglycemia Promotes TMPRSS2-ERG Gene Fusion in Prostate Cancer Cells via Upregulating Insulin-Like Growth Factor-Binding Protein-2.

Published in:

Frontiers in Endocrinology, 2017, p. 1, doi. 10.3389/fendo.2017.00305

By:

Holly, Jeff M. P.;
Broadhurst, Jessica;
Mansor, Rehanna;
Bahl, Amit;
Perks, Claire M.

Publication type:

Article

The Role of Insulin-like Growth Factor Binding Protein (IGFBP)-2 in DNA Repair and Chemoresistance in Breast Cancer Cells.

Published in:

Cancers, 2024, v. 16, n. 11, p. 2113, doi. 10.3390/cancers16112113

By:

Mohammedali, Alaa;
Biernacka, Kalina;
Barker, Rachel M.;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Alteration of Metabolic Conditions Impacts the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer.

Published in:

Cancers, 2021, v. 13, n. 4, p. 825, doi. 10.3390/cancers13040825

By:

Kingshott, Georgina;
Biernacka, Kalina;
Sewell, Alex;
Gwiti, Paida;
Barker, Rachel;
Zielinska, Hanna;
Gilkes, Amanda;
McCarthy, Kathryn;
Martin, Richard M.;
Lane, J. Athene;
McGeagh, Lucy;
Koupparis, Anthony;
Rowe, Edward;
Oxley, Jon;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3821, doi. 10.3390/cancers12123821

By:

Zielinska, Hanna A.;
Daly, Carl S.;
Alghamdi, Ahmad;
Bahl, Amit;
Sohail, Muhammed;
White, Paul;
Dean, Sarah R.;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid.

Published in:

Journal of Cellular Physiology, 2007, v. 211, n. 1, p. 244, doi. 10.1002/jcp.20922

By:

Sabin, Matthew A.;
Stewart, Claire E. H.;
Crowne, Elizabeth C.;
Turner, Stephen J.;
Hunt, Linda P.;
Welsh, Gavin I.;
Grohmann, Malcolm J.;
Holly, Jeff M. P.;
Shield, Julian P. H.

Publication type:

Article

Role of insulin-like growth factor binding protein-3 (IGFBP-3) in the differentiation of primary human adult skeletal myoblasts.

Published in:

Journal of Cellular Physiology, 2003, v. 195, n. 1, p. 70, doi. 10.1002/jcp.10227

By:

Emily J. Foulstone;
Paul B. Savage;
Anna L. Crown;
Jeff M.P. Holly;
Claire E.H. Stewart

Publication type:

Article

Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNFα-induced apoptosis.

Published in:

Journal of Cellular Physiology, 2001, v. 189, n. 2, p. 207, doi. 10.1002/jcp.10017

By:

Foulstone, Emily J.;
Meadows, Kate A.;
Holly, Jeff M.P.;
Stewart, Claire E.H.

Publication type:

Article

Tumor necrosis factor-α-induced apoptosis is associated with suppression of insulin-like growth factor binding protein-5 secretion in differentiating murine skeletal myoblasts.

Published in:

Journal of Cellular Physiology, 2000, v. 183, n. 3, p. 330, doi. 10.1002/(SICI)1097-4652(200006)183:3<330::AID-JCP5>3.0.CO;2-N

By:

Meadows, Kate A.;
Holly, Jeff M.P.;
Stewart, Claire E.H.

Publication type:

Article

Blood lipids and prostate cancer: a Mendelian randomization analysis.

Published in:

Cancer Medicine, 2016, v. 5, n. 6, p. 1125, doi. 10.1002/cam4.695

By:

Bull, Caroline J.;
Bonilla, Carolina;
Holly, Jeff M. P.;
Perks, Claire M.;
Davies, Neil;
Haycock, Philip;
Yu, Oriana Hoi Yun;
Richards, J. Brent;
Eeles, Rosalind;
Easton, Doug;
Kote ‐ Jarai, Zsofia;
Amin Al Olama, Ali;
Benlloch, Sara;
Muir, Kenneth;
Giles, Graham G.;
MacInnis, Robert J.;
Wiklund, Fredrik;
Gronberg, Henrik;
Haiman, Christopher A.;
Schleutker, Johanna

Publication type:

Article

The Role of Insulin-Like Growth Factor Binding Proteins.

Published in:

Neuroendocrinology, 2006, v. 83, n. 3/4, p. 154, doi. 10.1159/000095523

By:

Holly, Jeff;
Perks, Claire

Publication type:

Article

How growth hormone may be linked to cancer: concerns and perspective.

Published in:

Expert Review of Endocrinology & Metabolism, 2007, v. 2, n. 6, p. 759, doi. 10.1586/17446651.2.6.759

By:

Holly, Jeff M. P.;
Foulstone, Emily J.;
Perks, Claire M.

Publication type:

Article

Higher levels of IGF-I and adrenal androgens at age 8 years are associated with earlier age at menarche in girls.

Published in:

2012

By:

Thankamony A;
Ong KK;
Ahmed ML;
Ness AR;
Holly JM;
Dunger DB;
Thankamony, Ajay;
Ong, Ken K;
Ahmed, M Lynn;
Ness, Andrew R;
Holly, Jeff M P;
Dunger, David B

Publication type:

journal article

Changes in insulin-like growth factor-I and -II associated with fat but not lean mass in early old age.

Published in:

Obesity (19307381), 2015, v. 23, n. 3, p. 692, doi. 10.1002/oby.21002

By:

Bann, David;
Holly, Jeff M.P.;
Lashen, Hany;
Hardy, Rebecca;
Adams, Judith;
Kuh, Diana;
Ong, Ken K.;
Ben‐Shlomo, Yoav

Publication type:

Article