Works by Hollingshead, Melinda

Results: 33

Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas.

Published in:

Cancer Chemotherapy & Pharmacology, 2025, v. 95, n. 1, p. 1, doi. 10.1007/s00280-025-04778-5

By:

O'Sullivan Coyne, Geraldine;
Kummar, Shivaani;
Rubinstein, Larry V.;
Wilsker, Deborah;
Moore, Nancy;
Hogu, Murielle;
Piekarz, Richard;
Covey, Joe;
Beumer, Jan H.;
Ferry-Galow, Katherine V.;
Villaruz, Liza C.;
Hollingshead, Melinda G.;
Holleran, Julianne L.;
Deppas, Joshua J.;
Pommier, Yves;
Ko, Brian;
Johnson, Barry C.;
Parchhment, Ralph E.;
Ivy, Percy;
Doroshow, James H.

Publication type:

Article

Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0199361

By:

Navas, Tony;
Pfister, Thomas D.;
Colantonio, Simona;
Aziz, Amina;
Dieckman, Lynda;
Saul, Richard G.;
Kaczmarczyk, Jan;
Borgel, Suzanne;
Alcoser, Sergio Y.;
Hollingshead, Melinda G.;
Lee, Young H.;
Bottaro, Donald P.;
Hiltke, Tara;
Whiteley, Gordon;
Takebe, Naoko;
Kinders, Robert J.;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC.

Published in:

BMC Cancer, 2009, v. 9, p. 1, doi. 10.1186/1471-2407-9-63

By:

Stockwin, Luke H.;
Yu, Sherry X.;
Stotler, Howard;
Hollingshead, Melinda G.;
Newton, Dianne L.

Publication type:

Article

“Glowing Head” Mice: A Genetic Tool Enabling Reliable Preclinical Image-Based Evaluation of Cancers in Immunocompetent Allografts.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0109956

By:

Day, Chi-Ping;
Carter, John;
Ohler, Zoe Weaver;
Bonomi, Carrie;
El Meskini, Rajaa;
Martin, Philip;
Graff-Cherry, Cari;
Feigenbaum, Lionel;
Tüting, Thomas;
Van Dyke, Terry;
Hollingshead, Melinda;
Merlino, Glenn

Publication type:

Article

A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057099

By:

Mertins, Susan D.;
Scudiero, Dominic A.;
Hollingshead, Melinda G.;
Divelbiss Jr, Raymond D.;
Alley, Michael C.;
Monks, Anne;
Covell, David G.;
Hite, Karen M.;
Salomon, David S.;
Niederhuber, John E.

Publication type:

Article

Development and Validation of an Immunoassay for Quantification of Topoisomerase I in Solid Tumor Tissues.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050494

By:

Pfister, Thomas D.;
Hollingshead, Melinda;
Kinders, Robert J.;
Zhang, Yiping;
Evrard, Yvonne A.;
Ji, Jiuping;
Khin, Sonny A.;
Borgel, Suzanne;
Stotler, Howard;
Carter, John;
Divelbiss, Raymond;
Kummar, Shivaani;
Pommier, Yves;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Identification of CBX3 and ABCA5 as Putative Biomarkers for Tumor Stem Cells in Osteosarcoma.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0041401

By:

Saini, Vaibhav;
Hose, Curtis D.;
Monks, Anne;
Nagashima, Kunio;
Han, Bingnan;
Newton, Dianne L.;
Millione, Angelena;
Shah, Jalpa;
Hollingshead, Melinda G.;
Hite, Karen M.;
Burkett, Mark W.;
Delosh, Rene M.;
Silvers, Thomas E.;
Scudiero, Dominic A.;
Shoemaker, Robert H.;
Marie, Pierre J.

Publication type:

Article

Antitumor Activity of a Novel Oncrasin Analogue Is Mediated by JNK Activation and STAT3 Inhibition.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028487

By:

Wei Guo;
Shuhong Wu;
Li Wang;
Xiaoli Wei;
Xiaoying Liu;
Ji Wang;
Zhimin Lu;
Hollingshead, Melinda;
Bingliang Fang

Publication type:

Article

3'-[<sup>18</sup>F]fluoro-3'-deoxythymidine ([<sup>18</sup>F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor.

Published in:

2022

By:

Tatum, James L.;
Kalen, Joseph D.;
Jacobs, Paula M.;
Riffle, Lisa A.;
James, Amy;
Thang, Lai;
Sanders, Chelsea;
Hollingshead, Melinda G.;
Basuli, Falguni;
Shi, Jianfeng;
Doroshow, James H.

Publication type:

journal article

A phase I and pharmacokinetic study of oral perifosine with different loading schedules in patients with refractory neoplasms.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 955, doi. 10.1007/s00280-014-2569-7

By:

Figg, William;
Monga, Manish;
Headlee, Donna;
Shah, Avni;
Chau, Cindy;
Peer, Cody;
Messman, Richard;
Elsayed, Yusri;
Murgo, Anthony;
Melillo, Giovanni;
Ryan, Qin;
Kalnitskiy, Mikhail;
Senderowicz, Adrian;
Hollingshead, Melinda;
Arbuck, Susan;
Sausville, Edward

Publication type:

Article

Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.

Published in:

2014

By:

Thottassery, Jaideep V;
Sambandam, Vijaya;
Allan, Paula W;
Maddry, Joseph A;
Maxuitenko, Yulia Y;
Tiwari, Kamal;
Hollingshead, Melinda;
Parker, William B

Publication type:

journal article

Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4′-thio-2′-deoxycytidine and 5-aza-4′-thio-2′-deoxycytidine.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 291, doi. 10.1007/s00280-014-2503-z

By:

Thottassery, Jaideep;
Sambandam, Vijaya;
Allan, Paula;
Maddry, Joseph;
Maxuitenko, Yulia;
Tiwari, Kamal;
Hollingshead, Melinda;
Parker, William

Publication type:

Article

In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 2, p. 115, doi. 10.1007/s00280-004-0939-2

By:

Hollingshead, Melinda;
Alley, Michael;
Burger, Angelika M.;
Borgel, Suzanne;
Pacula-Cox, Christine;
Fiebig, Heinz-Herbert;
Sausville, Edward A.

Publication type:

Article

Therapeutic advantage from combining paclitaxel with the hypoxia-selective cytotoxin NLCQ-1 in murine tumor- or human xenograft-bearing mice.

Published in:

Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 6, p. 501, doi. 10.1007/s00280-002-0521-8

By:

Papadopoulou, Maria V.;
Ji, Ming;
Ji, Xinhai;
Bloomer, William D.;
Hollingshead, Melinda G.

Publication type:

Article

Response: Re: Antitumor Efficacy Testing in Rodents.

Published in:

2009

By:

HOLLINGSHEAD, MELINDA G.

Publication type:

Letter

Antitumor Efficacy Testing in Rodents.

Published in:

JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 21, p. 100, doi. 10.1093/jnci/djn351

By:

Hollingshead, Melinda G.

Publication type:

Article

Medroxyprogesterone Acetate Elevation of Nm23-H1 Metastasis Suppressor Expression in Hormone Receptor-Negative Breast Cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 2005, v. 97, n. 9, p. 632, doi. 10.1093/jnci/dji111

By:

Palmieri, Diane;
Halverson, Douglas O.;
Ouatas, Taoufik;
Horak, Christine E.;
Salerno, Massimiliano;
Johnson, Jennifer;
Figg, W. Douglas;
Hollingshead, Melinda;
Hursting, Stephen;
Berrigan, David;
Steinberg, Seth M.;
Merino, Maria J.;
Steeg, Patricia S.

Publication type:

Article

Exploiting embryonic niche conditions to grow Wilms tumor blastema in culture.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1091274

By:

Wojcik, Heather M.;
Lovvorn III, Harold N.;
Hollingshead, Melinda;
Pierce, Janene;
Stotler, Howard;
Murphy, Andrew J.;
Borgel, Suzanne;
Phelps, Hannah M.;
Correa, Hernan;
Perantoni, Alan O.

Publication type:

Article

Preclinical therapeutic response of residual metastatic disease is distinct from its primary tumor of origin.

Published in:

International Journal of Cancer, 2012, v. 130, n. 1, p. 190, doi. 10.1002/ijc.25978

By:

Day, Chi-Ping;
Carter, John;
Bonomi, Carrie;
Hollingshead, Melinda;
Merlino, Glenn

Publication type:

Article

Erratum: Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.

Published in:

International Journal of Cancer, 2010, v. 127, n. 11, p. E1, doi. 10.1002/ijc.25379

By:

Stockwin, Luke H.;
Han, Bingnan;
Yu, Sherry X.;
Hollingshead, Melinda G.;
ElSohly, Mahmoud A.;
Gul, Waseem;
Slade, Desmond;
Galal, Ahmed M.;
Newton, Dianne L.

Publication type:

Article

Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.

Published in:

International Journal of Cancer, 2010, v. 127, n. 11, p. 2510, doi. 10.1002/ijc.25499

By:

Stockwin, Luke H.;
Yu, Sherry X.;
Borgel, Suzanne;
Hancock, Chad;
Wolfe, Tracy L.;
Phillips, Lawrence R.;
Hollingshead, Melinda G.;
Newton, Dianne L.

Publication type:

Article

Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.

Published in:

International Journal of Cancer, 2009, v. 125, n. 6, p. 1266, doi. 10.1002/ijc.24496

By:

Stockwin, Luke H.;
Han, Bingnan;
Yu, Sherry X.;
Hollingshead, Melinda G.;
ElSohly, Mahmoud A.;
Gul, Waseem;
Slade, Desmond;
Galal, Ahmed M.;
Newton, Dianne L.

Publication type:

Article

TET2 and DNMT3A mutations and exceptional response to 4′-thio-2′-deoxycytidine in human solid tumor models.

Published in:

Journal of Hematology & Oncology, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13045-021-01091-5

By:

Yang, Sherry X.;
Hollingshead, Melinda;
Rubinstein, Larry;
Nguyen, Dat;
Larenjeira, Angelo B. A.;
Kinders, Robert J.;
Difilippantonio, Michael;
Doroshow, James H.

Publication type:

Article

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171582

By:

Ji, Jiuping;
Zhang, Yiping;
Redon, Christophe E.;
Reinhold, William C.;
Chen, Alice P.;
Fogli, Laura K.;
Holbeck, Susan L.;
Parchment, Ralph E.;
Hollingshead, Melinda;
Tomaszewski, Joseph E.;
Dudon, Quentin;
Pommier, Yves;
Doroshow, James H.;
Bonner, William M.

Publication type:

Article

Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages - strategies for data mining in support of therapeutic studies.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-393

By:

Hollingshead, Melinda G.;
Stockwin, Luke H.;
Alcoser, Sergio Y.;
Newton, Dianne L.;
Orsburn, Benjamin C.;
Bonomi, Carrie A.;
Borgel, Suzanne D.;
Divelbiss, Raymond;
Dougherty, Kelly M.;
Hager, Elizabeth J.;
Holbeck, Susan L.;
Kaur, Gurmeet;
Kimmel, David J.;
Kunkel, Mark W.;
Millione, Angelena;
Mullendore, Michael E.;
Stotler, Howard;
Collins, Jerry

Publication type:

Article

Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer.

Published in:

2012

By:

Bennett, Christina N;
Tomlinson, Christine C;
Michalowski, Aleksandra M;
Chu, Isabel M;
Luger, Dror;
Mittereder, Lara R;
Aprelikova, Olga;
Shou, James;
Piwinica-Worms, Helen;
Caplen, Natasha J;
Hollingshead, Melinda G;
Green, Jeffrey E

Publication type:

journal article

Lentivirus-mediated bifunctional cell labeling for in vivo melanoma study.

Published in:

Pigment Cell & Melanoma Research, 2009, v. 22, n. 3, p. 283, doi. 10.1111/j.1755-148X.2009.00545.x

By:

Day, Chi-Ping;
Carter, John;
Bonomi, Carrie;
Esposito, Dominic;
Crise, Bruce;
Ortiz-Conde, Betty;
Hollingshead, Melinda;
Merlino, Glenn

Publication type:

Article

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1.

Published in:

Molecular Cancer, 2008, v. 7, p. 1, doi. 10.1186/1476-4598-7-29

By:

Wright, Mollie H.;
Robles, Ana I.;
Herschkowitz, Jason I.;
Hollingshead, Melinda G.;
Anver, Miriam R.;
Perou, Charles M.;
Varticovski, Lyuba

Publication type:

Article

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32509-4

By:

Laranjeira, Angelo B. A.;
Hollingshead, Melinda G.;
Nguyen, Dat;
Kinders, Robert J.;
Doroshow, James H.;
Yang, Sherry X.

Publication type:

Article

Complex Display of Putative Tumor Stem Cell Markers in the NCI60 Tumor Cell Line Panel.

Published in:

Stem Cells, 2010, v. 28, n. 4, p. 649, doi. 10.1002/stem.324

By:

STUELTEN, CHRISTINA H.;
MKRTINS, SUSAN D.;
BUSCH, JOHANNA I.;
GOWENS, MEGHAN;
SCUDIERO, DOMINIC A.;
BURKETT, MARK W.;
HITE, KAREN M.;
ALLEY, MIKE;
HOLLINGSHEAD, MELINDA.;
SHOEMAKER, ROBERT H.;
NIKDERHIBER, JOHN E.

Publication type:

Article

Growth and chemotherapeutic response of cells in a hollow-fiber in vitro solid tumor model.

Published in:

JNCI: Journal of the National Cancer Institute, 1994, v. 86, n. 24, p. 1846, doi. 10.1093/jnci/86.24.1846

By:

Casciari, Joseph J.;
Hollingshead, Melinda G.

Publication type:

Article

Naturally Acquired Mouse Kidney Parvovirus Infection Produces a Persistent Interstitial Nephritis in Immunocompetent Laboratory Mice.

Published in:

Veterinary Pathology, 2020, v. 57, n. 6, p. 915, doi. 10.1177/0300985820953500

By:

Edmondson, Elijah F.;
Hsieh, Wang-Ting;
Kramer, Josh A.;
Breed, Matthew W.;
Roelke-Parker, Melody E.;
Stephens-Devalle, Julie;
Pate, Nathan M.;
Bassel, Laura L.;
Hollingshead, Melinda G.;
Karim, Baktiar O.;
Butcher, Donna O.;
Warner, Andrew C.;
Nagashima, Kunio;
Gulani, Jatinder

Publication type:

Article

A spontaneously metastatic model of bladder cancer: imaging characterization.

Published in:

2019

By:

Tatum, James L.;
Kalen, Joseph D.;
Jacobs, Paula M.;
Ileva, Lilia V.;
Riffle, Lisa A.;
Hollingshead, Melinda G.;
Doroshow, James H.

Publication type:

journal article