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KRAS , a New Target for Precision Medicine in Colorectal Cancer?
Published in:
Cancers, 2024, v. 16, n. 20, p. 3455, doi. 10.3390/cancers16203455
By:
- Boilève, Alice;
- Smolenschi, Cristina;
- Lambert, Aurélien;
- Boige, Valérie;
- Delaye, Matthieu;
- Camilleri, Géraldine M.;
- Tarabay, Anthony;
- Valéry, Marine;
- Fuerea, Alina;
- Pudlarz, Thomas;
- Mathieu, Jacques R. R.;
- Jaulin, Fanny;
- Hollebecque, Antoine;
- Ducreux, Michel
Publication type:
Article
Phase I dose-escalation study of pazopanib combined with bevacizumab in patients with metastatic renal cell carcinoma or other advanced tumors.
Published in:
2017
By:
- Négrier, Sylvie;
- Pérol, David;
- Bahleda, Rastislav;
- Hollebecque, Antoine;
- Chatelut, Etienne;
- Boyle, Helen;
- Cassier, Philippe;
- Metzger, Séverine;
- Blanc, Ellen;
- Soria, Jean-Charles;
- Escudier, Bernard
Publication type:
journal article
Oxaliplatin-induced peripheral neuropathy with hepatic arterial versus intravenous infusion in metastatic colorectal cancer.
Published in:
Supportive Care in Cancer, 2024, v. 32, n. 10, p. 1, doi. 10.1007/s00520-024-08807-6
By:
- Valéry, Marine;
- Tanguy, Marie-Laure;
- Gelli, Maximiliano;
- Smolenschi, Cristina;
- Hollebecque, Antoine;
- Boilève, Alice;
- de Sevilla, Elena Fernandez;
- Tselikas, Lambros;
- Bonnet, Baptiste;
- Goéré, Diane;
- Taïeb, Julien;
- Boige, Valérie;
- Ducreux, Michel;
- Malka, David
Publication type:
Article
Case Report: Response to Immunotherapy, Can Radiotherapy Be a Troublemaker?
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.745146
By:
- Martin-Romano, Patricia;
- Adam, Julien;
- Scoazec, Jean-Yves;
- Gouy, Sébastien;
- Levy, Antonin;
- Baldini, Capucine;
- Champiat, Stéphane;
- Soria, Jean-Charles;
- Massard, Christophe;
- Marabelle, Aurélien;
- Deutsch, Eric;
- Hollebecque, Antoine
Publication type:
Article
Conversion to Complete Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Malignant Peritoneal Mesothelioma After Bidirectional Chemotherapy.
Published in:
Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2017, v. 24, n. 12, p. 3640, doi. 10.1245/s10434-017-6033-x
By:
- Le Roy, Florence;
- Gelli, Maximiliano;
- Hollebecque, Antoine;
- Honoré, Charles;
- Boige, Valerie;
- Dartigues, Peggy;
- Benhaim, Leonor;
- Malka, David;
- Ducreux, Michel;
- Elias, Dominique;
- Goéré, Diane
Publication type:
Article
Retrospective analysis of real-world data to evaluate actionability of a comprehensive molecular profiling panel in solid tumor tissue samples (REALM study).
Published in:
PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0291495
By:
- Leroy, Karen;
- Audigier Valette, Clarisse;
- Alexandre, Jérôme;
- Boussemart, Lise;
- Chiesa, Jean;
- Deldycke, Clotilde;
- Gomez-Rocca, Carlos;
- Hollebecque, Antoine;
- Lehmann-Che, Jacqueline;
- Lemoine, Antoinette;
- Mansard, Sandrine;
- Medioni, Jacques;
- Monnet, Isabelle;
- Mourah, Samia;
- Pierret, Thomas;
- Spaëth, Dominique;
- Civet, Alexandre;
- Galoin, Sandrine;
- Italiano, Antoine
Publication type:
Article
A first-in-human phase I study of TAS0728, an oral covalent binding inhibitor of HER2, in patients with advanced solid tumors with HER2 or HER3 aberrations.
Published in:
Investigational New Drugs, 2021, v. 39, n. 5, p. 1324, doi. 10.1007/s10637-021-01104-7
By:
- Piha-Paul, Sarina A.;
- Azaro, Analía;
- Arkenau, Hendrik Tobias;
- Oh, Do-Youn;
- Galsky, Matthew D.;
- Pal, Sumanta Kumar;
- Hamada, Kensuke;
- He, Yaohua;
- Yamamiya, Ikuo;
- Benhadji, Karim A;
- Hollebecque, Antoine
Publication type:
Article
Phase I trial of bortezomib daily dose: safety, pharmacokinetic profile, biological effects and early clinical evaluation in patients with advanced solid tumors.
Published in:
Investigational New Drugs, 2018, v. 36, n. 4, p. 619, doi. 10.1007/s10637-017-0531-3
By:
- Bahleda, Rastislav;
- Le Deley, Marie-Cécile;
- Bernard, Apexa;
- Chaturvedi, Shalini;
- Hanley, Michael;
- Poterie, Audrey;
- Gazzah, Anas;
- Varga, Andreea;
- Touat, Mehdi;
- Deutsch, Eric;
- Massard, Christophe;
- Van De Velde, Helgi;
- Hollebecque, Antoine;
- Sallansonnet-Froment, Magali;
- Ricard, Damien;
- Taillia, Hervé;
- Angevin, Eric;
- Ribrag, Vincent;
- Soria, Jean-Charles
Publication type:
Article
Outcomes and prognostic factors for relapsed or refractory lymphoma patients in phase I clinical trials.
Published in:
Investigational New Drugs, 2018, v. 36, n. 1, p. 62, doi. 10.1007/s10637-017-0480-x
By:
- Michot, Jean-Marie;
- Benajiba, Lina;
- Faivre, Laura;
- Baldini, Capucine;
- Haddag, Lelia;
- Bonnet, Clement;
- Massard, Christophe;
- Bigot, Frederic;
- Bigenwald, Camille;
- Verret, Benjamin;
- Thomas, Zoé A. P.;
- Varga, Andrea;
- Gazzah, Anas;
- Hollebecque, Antoine;
- Ghez, David;
- Lazarovici, Julien;
- Balheda, Rastilav;
- Jeanson, Aurore;
- Postel-Vinay, Sophie;
- Danu, Alina
Publication type:
Article
Predictive factors of renal toxicities related to anti-VEGFR multikinase inhibitors in phase 1 trials.
Published in:
Investigational New Drugs, 2017, v. 35, n. 1, p. 79, doi. 10.1007/s10637-016-0402-3
By:
- Boissier, Emilie;
- Mir, Olivier;
- Hollebecque, Antoine;
- Izzedine, Hassan;
- Ederhy, Stéphane;
- Gazzah, Anas;
- Bahleda, Rastislav;
- Massard, Christophe;
- Macquin-Mavier, Isabelle;
- Tournigand, Christophe;
- Spano, Jean-Philippe;
- Soria, Jean-Charles;
- Rousseau, Benoît
Publication type:
Article
Sequence analyses of relapsed or refractory diffuse large B‐cell lymphomas unravel three genetic subgroups of patients and the GNA13 mutant as poor prognostic biomarker, results of LNH‐EP1 study.
Published in:
American Journal of Hematology, 2023, v. 98, n. 4, p. 645, doi. 10.1002/ajh.26835
By:
- Michot, Jean‐Marie;
- Quivoron, Cyril;
- Sarkozy, Clémentine;
- Danu, Alina;
- Lazarovici, Julien;
- Saleh, Khalil;
- El‐Dakdouki, Yolla;
- Goldschmidt, Vincent;
- Bigenwald, Camille;
- Dragani, Matteo;
- Bahleda, Rastislav;
- Baldini, Capucine;
- Arfi‐Rouche, Julia;
- Martin‐Romano, Patricia;
- Tselikas, Lambros;
- Gazzah, Anas;
- Hollebecque, Antoine;
- Lacroix, Ludovic;
- Ghez, David;
- Vergé, Veronique
Publication type:
Article
Innovative therapies based on molecular orientation in patients with relapse and refractory diffuse large B‐cell lymphoma: Results of LNH‐EP1 study.
Published in:
American Journal of Hematology, 2021, v. 96, n. 10, p. E376, doi. 10.1002/ajh.26280
By:
- Sarkozy, Clémentine;
- Michot, Jean‐Marie;
- Quivoron, Cyril;
- Camara‐Clayette, Valérie;
- Danu, Alina;
- Lazarovici, Julien;
- El‐Dakdouki, Yolla;
- Saleh, Khalil;
- Ghez, David;
- Rossignol, Julien;
- Baldini, Capucine;
- Arfi‐Rouche, Julia;
- Romano‐Martin, Patricia;
- Tselikas, Lambros;
- Varga, Andrea;
- Gazzah, Anas;
- Hollebecque, Antoine;
- Lacroix, Ludovic;
- Bahleda, Rastislav;
- Lecourt, Hélène
Publication type:
Article
Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: Prognostic Factors of Local Control, Overall Survival, and Toxicity.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077472
By:
- Bibault, Jean-Emmanuel;
- Dewas, Sylvain;
- Vautravers-Dewas, Claire;
- Hollebecque, Antoine;
- Jarraya, Hajer;
- Lacornerie, Thomas;
- Lartigau, Eric;
- Mirabel, Xavier
Publication type:
Article
Development and Validation of a Bedside Score to Predict Early Death in Cancer of Unknown Primary Patients.
Published in:
PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006483
By:
- Penel, Nicolas;
- Negrier, Sylvie;
- Ray-Coquard, Isabelle;
- Ferte, Charles;
- Devos, Patrick;
- Hollebecque, Antoine;
- Sawyer, Michael B.;
- Adenis, Antoine;
- Seve, Pascal
Publication type:
Article
Patterns of progression in patients treated for immuno-oncology antibodies combination.
Published in:
Cancer Immunology, Immunotherapy, 2021, v. 70, n. 1, p. 221, doi. 10.1007/s00262-020-02647-z
By:
- Bernard-Tessier, Alice;
- Baldini, Capucine;
- Castanon, Eduardo;
- Martin, Patricia;
- Champiat, Stéphane;
- Hollebecque, Antoine;
- Postel-Vinay, Sophie;
- Varga, Andreea;
- Bahleda, Rastilav;
- Gazzah, Anas;
- Michot, Jean-Marie;
- Ribrag, Vincent;
- Armand, Jean-Pierre;
- Marabelle, Aurélien;
- Soria, Jean-Charles;
- Massard, Christophe;
- Ammari, Samy
Publication type:
Article
Targetable Molecular Alterations in the Treatment of Biliary Tract Cancers: An Overview of the Available Treatments.
Published in:
Cancers, 2023, v. 15, n. 18, p. 4446, doi. 10.3390/cancers15184446
By:
- Valery, Marine;
- Vasseur, Damien;
- Fachinetti, Francesco;
- Boilève, Alice;
- Smolenschi, Cristina;
- Tarabay, Anthony;
- Antoun, Leony;
- Perret, Audrey;
- Fuerea, Alina;
- Pudlarz, Thomas;
- Boige, Valérie;
- Hollebecque, Antoine;
- Ducreux, Michel
Publication type:
Article
Predicting Immunotherapy Outcomes in Older Patients with Solid Tumors Using the LIPI Score.
Published in:
Cancers, 2022, v. 14, n. 20, p. 5078, doi. 10.3390/cancers14205078
By:
- Pierro, Monica;
- Baldini, Capucine;
- Auclin, Edouard;
- Vincent, Hélène;
- Varga, Andreea;
- Martin Romano, Patricia;
- Vuagnat, Perrine;
- Besse, Benjamin;
- Planchard, David;
- Hollebecque, Antoine;
- Champiat, Stéphane;
- Marabelle, Aurélien;
- Michot, Jean-Marie;
- Massard, Christophe;
- Mezquita, Laura
Publication type:
Article
Immunotherapy and Hepatocellular Cancer: Where Are We Now?
Published in:
Cancers, 2022, v. 14, n. 18, p. N.PAG, doi. 10.3390/cancers14184523
By:
- Valery, Marine;
- Cervantes, Baptiste;
- Samaha, Ramy;
- Gelli, Maximiliano;
- Smolenschi, Cristina;
- Fuerea, Alina;
- Tselikas, Lambros;
- Klotz-Prieux, Caroline;
- Hollebecque, Antoine;
- Boige, Valérie;
- Ducreux, Michel
Publication type:
Article
Treatments after Immune Checkpoint Inhibitors in Patients with dMMR/MSI Metastatic Colorectal Cancer.
Published in:
Cancers, 2022, v. 14, n. 2, p. 406, doi. 10.3390/cancers14020406
By:
- Bui, Quang Loc;
- Mas, Léo;
- Hollebecque, Antoine;
- Tougeron, David;
- de la Fouchardière, Christelle;
- Pudlarz, Thomas;
- Alouani, Emily;
- Guimbaud, Rosine;
- Taieb, Julien;
- André, Thierry;
- Colle, Raphaël;
- Cohen, Romain
Publication type:
Article
Association of the Lung Immune Prognostic Index with Immunotherapy Outcomes in Mismatch Repair Deficient Tumors.
Published in:
Cancers, 2021, v. 13, n. 15, p. 3776, doi. 10.3390/cancers13153776
By:
- Auclin, Edouard;
- Vuagnat, Perrine;
- Smolenschi, Cristina;
- Taieb, Julien;
- Adeva, Jorge;
- Nebot-Bral, Laetitia;
- Garcia de Herreros, Marta;
- Vidal Tocino, Rosario;
- Longo-Muñoz, Federico;
- El Dakdouki, Yola;
- Martín-Romano, Patricia;
- Gaba, Lydia;
- Saurí, Tamara;
- Oliveres, Helena;
- Castañón, Eduardo;
- Garcia-Carbonero, Rocio;
- Besse, Benjamin;
- Massard, Christophe;
- Mezquita, Laura;
- Hollebecque, Antoine
Publication type:
Article
Immunotherapy in Advanced Biliary Tract Cancers.
Published in:
Cancers, 2021, v. 13, n. 7, p. 1569, doi. 10.3390/cancers13071569
By:
- Boilève, Alice;
- Hilmi, Marc;
- Smolenschi, Cristina;
- Ducreux, Michel;
- Hollebecque, Antoine;
- Malka, David;
- Frampton, Adam E.
Publication type:
Article
Peroxisome Proliferator-Activated Receptors in HBV-Related Infection.
Published in:
PPAR Research, 2009, p. 1, doi. 10.1155/2009/145124
By:
- Dubuquoy, Laurent;
- Louvet, Alexandre;
- Hollebecque, Antoine;
- Mathurin, Philippe;
- Dharancy, Sébastien
Publication type:
Article
Management of biliary tract cancers in early‐onset patients: A nested multicenter retrospective study of the ACABI GERCOR PRONOBIL cohort.
Published in:
Liver International, 2024, v. 44, n. 8, p. 1886, doi. 10.1111/liv.15922
By:
- Lebeaud, Antoine;
- Antoun, Leony;
- Paccard, Jane‐Rose;
- Edeline, Julien;
- Bourien, Hélène;
- Fares, Nadim;
- Tournigand, Christophe;
- Lecomte, Thierry;
- Tougeron, David;
- Hautefeuille, Vincent;
- Viénot, Angélique;
- Henriques, Julie;
- Williet, Nicolas;
- Bachet, Jean‐Baptiste;
- Smolenschi, Cristina;
- Hollebecque, Antoine;
- Macarulla, Teresa;
- Castet, Florian;
- Malka, David;
- Neuzillet, Cindy
Publication type:
Article
Dysphonia induced by anti-angiogenic compounds.
Published in:
Investigational New Drugs, 2014, v. 32, n. 4, p. 774, doi. 10.1007/s10637-013-0049-2
By:
- Saavedra, Erika;
- Hollebecque, Antoine;
- Soria, Jean-Charles;
- Hartl, Dana
Publication type:
Article
Inadequacy of size-based response criteria to assess the efficacy of trabectedin among metastatic sarcoma patients.
Published in:
2010
By:
- Hollebecque, Antoine;
- Adenis, Antoine;
- Taieb, Sophie;
- Lebedinsky, Claudia;
- Penel, Nicolas
Publication type:
Report
Evidence of pseudoprogression in patients treated with PD1/PDL1 antibodies across tumor types.
Published in:
Cancer Medicine, 2020, v. 9, n. 8, p. 2643, doi. 10.1002/cam4.2797
By:
- Martin‐Romano, Patricia;
- Castanon, Eduardo;
- Ammari, Samy;
- Champiat, Stéphane;
- Hollebecque, Antoine;
- Postel‐Vinay, Sophie;
- Baldini, Capucine;
- Varga, Andrea;
- Michot, Jean Marie;
- Vuagnat, Perrine;
- Marabelle, Aurélien;
- Soria, Jean‐Charles;
- Ferté, Charles;
- Massard, Christophe
Publication type:
Article
Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47489-7
By:
- Mohan, Sumitra;
- Ayub, Mahmood;
- Rothwell, Dominic G.;
- Gulati, Sakshi;
- Kilerci, Bedirhan;
- Hollebecque, Antoine;
- Sun Leong, Hui;
- Smith, Nigel K.;
- Sahoo, Sudhakar;
- Descamps, Tine;
- Zhou, Cong;
- Hubner, Richard A.;
- McNamara, Mairéad G.;
- Lamarca, Angela;
- Valle, Juan W.;
- Dive, Caroline;
- Brady, Ged
Publication type:
Article
Clinical and molecular features of early onset pancreatic adenocarcinoma.
Published in:
International Journal of Cancer, 2024, v. 155, n. 11, p. 1969, doi. 10.1002/ijc.35135
By:
- Rémond, Maxime;
- Smolenschi, Cristina;
- Tarabay, Anthony;
- Gelli, Maximiliano;
- Fernandez‐de‐Sevilla, Elena;
- Mouawia, Ali;
- Cosconea, Simona;
- Tselikas, Lambros;
- Barbe, Remy;
- Fuerea, Alina;
- Bani, Mohamed A.;
- Deloger, Marc;
- Besse, Benjamin;
- Pudlarz, Thomas;
- Valéry, Marine;
- Boige, Valérie;
- Hollebecque, Antoine;
- Ducreux, Michel;
- Boilève, Alice
Publication type:
Article
Molecular targeted therapy of BRAF -mutant colorectal cancer.
Published in:
Therapeutic Advances in Medical Oncology, 2019, v. 11, p. 1, doi. 10.1177/1758835919856494
By:
- Ducreux, Michel;
- Chamseddine, Ali;
- Laurent-Puig, Pierre;
- Smolenschi, Cristina;
- Hollebecque, Antoine;
- Dartigues, Peggy;
- Samallin, Emmanuelle;
- Boige, Valérie;
- Malka, David;
- Gelli, Maximiliano
Publication type:
Article
Molecular targeted therapy of BRAF -mutant colorectal cancer.
Published in:
Therapeutic Advances in Medical Oncology, 2019, v. 11, p. N.PAG, doi. 10.1177/1758835919856494
By:
- Ducreux, Michel;
- Chamseddine, Ali;
- Laurent-Puig, Pierre;
- Smolenschi, Cristina;
- Hollebecque, Antoine;
- Dartigues, Peggy;
- Samallin, Emmanuelle;
- Boige, Valérie;
- Malka, David;
- Gelli, Maximiliano
Publication type:
Article
Development of a score that predicts survival among patients with bone metastasis revealing solid tumor.
Published in:
2008
By:
- Penel N;
- Hollebecque A;
- Maynou C;
- Dewaele J;
- Jasserand M;
- Beuscart R;
- Vieillard MH;
- Penel, Nicolas;
- Hollebecque, Antoine;
- Maynou, Carlos;
- Dewaele, Jérôme;
- Jasserand, Marie;
- Beuscart, Régis;
- Vieillard, Marie-Hélène
Publication type:
journal article
Experience of Gemcitabine plus Oxaliplatin Chemotherapy in Patients with Advanced Biliary Tract Carcinoma.
Published in:
Chemotherapy (0009-3157), 2010, v. 56, n. 3, p. 234, doi. 10.1159/000316848
By:
- Hollebecque, Antoine;
- Bouché, Olivier;
- Romano, Olivier;
- Scaglia, Elodie;
- Cattan, Stéphane;
- Zerbib, Philippe;
- Heurgue, Alexandra;
- Lagarde, Stéphanie;
- Mariette, Christophe;
- Triboulet, Jean-Pierre;
- Pruvot, François-René;
- Hebbar, Mohamed
Publication type:
Article
Resolving the Paradox of Colon Cancer Through the Integration of Genetics, Immunology, and the Microbiota.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.600886
By:
- Fidelle, Marine;
- Yonekura, Satoru;
- Picard, Marion;
- Cogdill, Alexandria;
- Hollebecque, Antoine;
- Roberti, Maria Paula;
- Zitvogel, Laurence
Publication type:
Article
Time to progression ratio in cancer patients enrolled in early phase clinical trials: time for new guidelines?
Published in:
2018
By:
- Watson, Sarah;
- Menis, Jessica;
- Baldini, Capucine;
- Martin-Romano, Patricia;
- Michot, Jean-Marie;
- Hollebecque, Antoine;
- Armand, Jean-Pierre;
- Massard, Christophe;
- Soria, Jean-Charles;
- Postel-Vinay, Sophie;
- Paoletti, Xavier
Publication type:
journal article
Phase I study of afatinib combined with nintedanib in patients with advanced solid tumours.
Published in:
2015
By:
- Bahleda, Rastislav;
- Hollebecque, Antoine;
- Varga, Andrea;
- Gazzah, Anas;
- Massard, Christophe;
- Deutsch, Eric;
- Amellal, Nadia;
- Farace, Françoise;
- Ould-Kaci, Mahmoud;
- Roux, Flavien;
- Marzin, Kristell;
- Soria, Jean-Charles;
- Farace, Françoise
Publication type:
journal article
Clinical Relevance of Alternative Endpoints in Colorectal Cancer First-Line Therapy With Bevacizumab: A Retrospective Study.
Published in:
2018
By:
- Turpin, Anthony;
- Paget-Bailly, Sophie;
- Ploquin, Anne;
- Hollebecque, Antoine;
- Peugniez, Charlotte;
- El-Hajbi, Farid;
- Bonnetain, Franck;
- Hebbar, Mohamed
Publication type:
journal article
Long-Term Overall Survival After Selective Internal Radiation Therapy for Locally Advanced Hepatocellular Carcinomas: Updated Analysis of DOSISPHERE-01 Trial.
Published in:
Journal of Nuclear Medicine, 2024, v. 65, n. 8, p. 1, doi. 10.2967/jnumed.123.266211
By:
- Garin, Etienne;
- Tselikas, Lambros;
- Guiu, Boris;
- Chalaye, Julia;
- Rolland, Yan;
- de Baere, Thierry;
- Assenat, Eric;
- Tacher, Vania;
- Palard, Xavier;
- Déandreis, Desirée;
- Mariano-Goulart, Denis;
- Amaddeo, Giuliana;
- Boudjema, Karim;
- Hollebecque, Antoine;
- Meerun, Mohamad Azhar;
- Regnault, Helen;
- Vibert, Eric;
- Campillo-Gimenez, Boris;
- Edeline, Julien
Publication type:
Article
Long-Term Overall Survival After Selective Internal Radiation Therapy for Locally Advanced Hepatocellular Carcinomas: Updated Analysis of DOSISPHERE-01 Trial.
Published in:
Journal of Nuclear Medicine, 2024, v. 65, n. 2, p. 1, doi. 10.2967/jnumed.123.266211
By:
- Garin, Etienne;
- Tselikas, Lambros;
- Guiu, Boris;
- Chalaye, Julia;
- Rolland, Yan;
- de Baere, Thierry;
- Assenat, Eric;
- Tacher, Vania;
- Palard, Xavier;
- Déandreis, Desirée;
- Mariano-Goulart, Denis;
- Amaddeo, Giuliana;
- Boudjema, Karim;
- Hollebecque, Antoine;
- Meerun, Mohamad Azhar;
- Regnault, Helen;
- Vibert, Eric;
- Campillo-Gimenez, Boris;
- Edeline, Julien
Publication type:
Article
Deciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development.
Published in:
Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02134-4
By:
- Vasseur, Damien;
- Bigot, Ludovic;
- Beshiri, Kristi;
- Flórez-Arango, Juan;
- Facchinetti, Francesco;
- Hollebecque, Antoine;
- Tselikas, Lambros;
- Aldea, Mihaela;
- Blanc-Durand, Felix;
- Gazzah, Anas;
- Planchard, David;
- Lacroix, Ludovic;
- Pata-Merci, Noémie;
- Nobre, Catline;
- Da Silva, Alice;
- Nicotra, Claudio;
- Ngo-Camus, Maud;
- Braye, Floriane;
- Nikolaev, Sergey I.;
- Michiels, Stefan
Publication type:
Article
Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.
Published in:
Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02092-x
By:
- Cousin, Sophie;
- Guégan, Jean-Philippe;
- Shitara, Kohei;
- Palmieri, Lola Jade;
- Metges, Jean Philippe;
- Pernot, Simon;
- Fukuoka, Shota;
- Koyama, Shohei;
- Nishikawa, Hiroyoshi;
- Bellera, Carine A.;
- Adenis, Antoine;
- Gomez-Roca, Carlos A.;
- Cassier, Philippe Alexandre;
- Hollebecque, Antoine;
- Cantarel, Coralie;
- Kind, Michèle;
- Soubeyran, Isabelle;
- Vanhersecke, Lucile;
- Bessede, Alban;
- Italiano, Antoine
Publication type:
Article
Circulating tumor DNA landscape and prognostic impact of acquired resistance to targeted therapies in cancer patients: a national center for precision medicine (PRISM) study.
Published in:
Molecular Cancer, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12943-023-01878-9
By:
- Bayle, Arnaud;
- Belcaid, Laila;
- Palmieri, Lola-Jade;
- Teysonneau, Diego;
- Cousin, Sophie;
- Spalato-Ceruso, Mariella;
- Aldea, Mihaela;
- Vasseur, Damien;
- Alame, Melissa;
- Blouin, Laura;
- Soubeyran, Isabelle;
- Nicotra, Claudio;
- Ngocamus, Maud;
- Hollebecque, Antoine;
- Loriot, Yohann;
- Besse, Benjamin;
- Lacroix, Ludovic;
- Rouleau, Etienne;
- Barlesi, Fabrice;
- Andre, Fabrice
Publication type:
Article
Phase I dose-escalation study of milciclib in combination with gemcitabine in patients with refractory solid tumors.
Published in:
2017
By:
- Aspeslagh, Sandrine;
- Shailubhai, Kunwar;
- Bahleda, Rastilav;
- Gazzah, Anas;
- Varga, Andréa;
- Hollebecque, Antoine;
- Massard, Christophe;
- Spreafico, Anna;
- Reni, Michele;
- Soria, Jean-Charles;
- Varga, Andréa
Publication type:
journal article
Pharmacokinetics of pazopanib administered in combination with bevacizumab.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 6, p. 1189, doi. 10.1007/s00280-014-2455-3
By:
- Imbs, Diane-Charlotte;
- Négrier, Sylvie;
- Cassier, Philippe;
- Hollebecque, Antoine;
- Varga, Andrea;
- Blanc, Ellen;
- Lafont, Thierry;
- Escudier, Bernard;
- Soria, Jean-Charles;
- Pérol, David;
- Chatelut, Etienne
Publication type:
Article
Patients aged over 75 years enrolled in Phase I clinical trials: the Gustave Roussy experience.
Published in:
International Journal of Cancer, 2016, v. 138, n. 4, p. 875, doi. 10.1002/ijc.29849
By:
- Helissey, Carole;
- Biondani, Pamela;
- Roquet, Florian;
- Lanoy, Emilie;
- Mir, Olivier;
- Varga, Andrea;
- Massard, Christophe;
- Gazzah, Anas;
- Ribrag, Vincent;
- Bahleda, Ratislav;
- Postel‐Vinay, Sophie;
- Angevin, Eric;
- Deutsch, Eric;
- Soria, Jean‐Charles;
- Hollebecque, Antoine
Publication type:
Article
A Case-Control Study Brings to Light the Causes of Screen Failures in Phase 1 Cancer Clinical Trials.
Published in:
PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0154895
By:
- Kempf, Emmanuelle;
- Lemoine, Nathalie;
- Tergemina-Clain, Gabrielle;
- Turpin, Anthony;
- Postel-Vinay, Sophie;
- Lanoy, Emilie;
- Soria, Jean-Charles;
- Massard, Christophe;
- Hollebecque, Antoine
Publication type:
Article
COLUMBIA-1: a randomised study of durvalumab plus oleclumab in combination with chemotherapy and bevacizumab in metastatic microsatellite-stable colorectal cancer.
Published in:
British Journal of Cancer, 2024, v. 131, n. 6, p. 1005, doi. 10.1038/s41416-024-02796-3
By:
- Segal, Neil H.;
- Tie, Jeanne;
- Kopetz, Scott;
- Ducreux, Michel;
- Chen, Eric;
- Dienstmann, Rodrigo;
- Hollebecque, Antoine;
- Reilley, Matthew J.;
- Elez, Elena;
- Cosaert, Jan;
- Cain, Jason;
- Soo-Hoo, Yee;
- Hewson, Nicola;
- Cooper, Zachary A.;
- Kumar, Rakesh;
- Tabernero, Josep
Publication type:
Article
Primary resistance to immunotherapy in patients with a dMMR/MSI metastatic gastrointestinal cancer: who is at risk? An AGEO real-world study.
Published in:
British Journal of Cancer, 2024, v. 130, n. 3, p. 442, doi. 10.1038/s41416-023-02524-3
By:
- Flecchia, Clémence;
- Auclin, Edouard;
- Alouani, Emily;
- Mercier, Mathilde;
- Hollebecque, Antoine;
- Turpin, Anthony;
- Mazard, Thibault;
- Pernot, Simon;
- Dutherage, Marie;
- Cohen, Romain;
- Borg, Christophe;
- Hautefeuille, Vincent;
- Sclafani, Francesco;
- Ben-Abdelghani, Meher;
- Aparicio, Thomas;
- De La Fouchardière, Christelle;
- Herve, Camille;
- Perkins, Geraldine;
- Heinrich, Kathrin;
- Kunzmann, Volker
Publication type:
Article
First-in-human, dose-escalation, phase 1 study of anti-angiopoietin-2 LY3127804 as monotherapy and in combination with ramucirumab in patients with advanced solid tumours.
Published in:
2020
By:
- Martin-Liberal, Juan;
- Hollebecque, Antoine;
- Aftimos, Philippe;
- Jungels, Christiane;
- Martin-Romano, Patricia;
- Rodon, Jordi;
- Kremer, Jill Dolores;
- Zhang, Wei;
- Bendell, Johanna
Publication type:
journal article
Feasibility and first reports of the MATCH-R repeated biopsy trial at Gustave Roussy.
Published in:
NPJ Precision Oncology, 2020, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41698-020-00130-7
By:
- Recondo, Gonzalo;
- Mahjoubi, Linda;
- Maillard, Aline;
- Loriot, Yohann;
- Bigot, Ludovic;
- Facchinetti, Francesco;
- Bahleda, Rastislav;
- Gazzah, Anas;
- Hollebecque, Antoine;
- Mezquita, Laura;
- Planchard, David;
- Naltet, Charles;
- Lavaud, Pernelle;
- Lacroix, Ludovic;
- Richon, Catherine;
- Lovergne, Aurelie Abou;
- De Baere, Thierry;
- Tselikas, Lambros;
- Deas, Olivier;
- Nicotra, Claudio
Publication type:
Article
Precision Medicine in Pancreatic Ductal Adenocarcinoma: The Impact of Targeted Therapies on Survival of Patients Harboring Actionable Mutations.
Published in:
Biomedicines, 2023, v. 11, n. 9, p. 2569, doi. 10.3390/biomedicines11092569
By:
- Tarabay, Anthony;
- Boileve, Alice;
- Smolenschi, Cristina;
- Antoun, Leony;
- Valery, Marine;
- Fuerea, Alina;
- Perret, Audrey;
- Burtin, Pascal;
- Cosconea, Simona;
- Belkhodja, Hichem;
- Malka, David;
- Boige, Valérie;
- Hollebecque, Antoine;
- Ducreux, Michel
Publication type:
Article

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