Works by Holland, Eric C

Results: 96

Aggressive high-grade NF2 mutant meningiomas downregulate oncogenic YAP signaling via the upregulation of VGLL4 and FAT3/4.

Published in:

Neuro-Oncology Advances, 2024, v. 6, n. 1, p. 1, doi. 10.1093/noajnl/vdae148

By:

Parrish, Abigail G;
Arora, Sonali;
Thirimanne, H Nayanga;
Rudoy, Dmytro;
Schmid, Sebastian;
Sievers, Philipp;
Sahm, Felix;
Holland, Eric C;
Szulzewsky, Frank

Publication type:

Article

Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery.

Published in:

Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0443-7

By:

Cimino, Patrick J.;
Zager, Michael;
McFerrin, Lisa;
Wirsching, Hans-Georg;
Bolouri, Hamid;
Hentschel, Bettina;
von Deimling, Andreas;
Jones, David;
Reifenberger, Guido;
Weller, Michael;
Holland, Eric C.

Publication type:

Article

Personalized Medicine for Gliomas.

Published in:

Surgical Neurology International, 2015, v. 6, p. S89, doi. 10.4103/2152-7806.151351

By:

Ene, Chibawanye I.;
Holland, Eric C.

Publication type:

Article

Regulation of Translation and Cancer.

Published in:

Cell Cycle, 2004, v. 3, n. 4, p. 452, doi. 10.4161/cc.3.4.796

By:

Holland, Eric C.

Publication type:

Article

Malignant Gliomas with Primitive Neuroectodermal Tumor-like Components: A Clinicopathologic and Genetic Study of 53 Cases.

Published in:

Brain Pathology, 2009, v. 19, n. 1, p. 81, doi. 10.1111/j.1750-3639.2008.00167.x

By:

Perry, Arie;
Miller, C. Ryan;
Gujrati, Meena;
Scheithauer, Bernd W.;
Zambrano, Sandro Casavilca;
Jost, Sarah C.;
Raghavan, Ravi;
Qian, Jiang;
Cochran, Elizabeth J.;
Huse, Jason T;
Holland, Eric C.;
Burger, Peter C.;
Rosenblum, Marc K.

Publication type:

Article

Genetically Engineered Mouse Models of Brain Cancer and the Promise of Preclinical Testing.

Published in:

Brain Pathology, 2009, v. 19, n. 1, p. 132, doi. 10.1111/j.1750-3639.2008.00234.x

By:

Huse, Jason T.;
Holland, Eric C.

Publication type:

Article

Angiogenin and plexin-B2 axis promotes glioblastoma progression by enhancing invasion, vascular association, proliferation and survival.

Published in:

2022

By:

Yang, Hailing;
Yuan, Liang;
Ibaragi, Soichiro;
Li, Shuping;
Shapiro, Robert;
Vanli, Nil;
Goncalves, Kevin A.;
Yu, Wenhao;
Kishikawa, Hiroko;
Jiang, Yuxiang;
Hu, Alexander J.;
Jay, Daniel;
Cochran, Brent;
Holland, Eric C.;
Hu, Guo-fu

Publication type:

journal article

Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma.

Published in:

EMBO Journal, 2014, v. 33, n. 18, p. 1984, doi. 10.15252/embj.201489479

By:

Becher, Oren J;
Holland, Eric C

Publication type:

Article

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas.

Published in:

EMBO Journal, 2011, v. 30, n. 19, p. 4084, doi. 10.1038/emboj.2011.259

By:

LeFave, Clare V;
Squatrito, Massimo;
Vorlova, Sandra;
Rocco, Gina L;
Brennan, Cameron W;
Holland, Eric C;
Pan, Ying-Xian;
Cartegni, Luca

Publication type:

Article

Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release.

Published in:

Molecular Systems Biology, 2021, v. 17, n. 9, p. 1, doi. 10.15252/msb.202110426

By:

Chan, Marina;
Vijay, Siddharth;
McNevin, John;
McElrath, M Juliana;
Holland, Eric C;
Gujral, Taranjit S

Publication type:

Article

Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma.

Published in:

Molecular Systems Biology, 2012, v. 8, n. 1, p. 605, doi. 10.1038/msb.2012.37

By:

Setty, Manu;
Helmy, Karim;
Khan, Aly A;
Silber, Joachim;
Arvey, Aaron;
Neezen, Frank;
Agius, Phaedra;
Huse, Jason T;
Holland, Eric C;
Leslie, Christina S

Publication type:

Article

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells.

Published in:

Journal of Neuro-Oncology, 2010, v. 97, n. 3, p. 323, doi. 10.1007/s11060-009-0035-x

By:

Ayuso-Sacido, Angel;
Moliterno, Jennifer A.;
Kratovac, Sebila;
Kapoor, Gurpreet S.;
O’Rourke, Donald M.;
Holland, Eric C.;
García-Verdugo, Jose Manuel;
Roy, Neeta S.;
Boockvar, John A.

Publication type:

Article

Leveraging the replication‐competent avian‐like sarcoma virus/tumor virus receptor‐A system for modeling human gliomas.

Published in:

Glia (0894-1491), 2021, v. 69, n. 9, p. 2059, doi. 10.1002/glia.23984

By:

Kanvinde, Pranjali P.;
Malla, Adarsha P.;
Connolly, Nina P.;
Szulzewsky, Frank;
Anastasiadis, Pavlos;
Ames, Heather M.;
Kim, Anthony J.;
Winkles, Jeffrey A.;
Holland, Eric C.;
Woodworth, Graeme F.

Publication type:

Article

Multimodal single‐cell analysis reveals distinct radioresistant stem‐like and progenitor cell populations in murine glioma.

Published in:

Glia (0894-1491), 2020, v. 68, n. 12, p. 2486, doi. 10.1002/glia.23866

By:

Alexander, Jes;
LaPlant, Quincey C.;
Pattwell, Siobhan S.;
Szulzewsky, Frank;
Cimino, Patrick J.;
Caruso, Francesca P.;
Pugliese, Pietro;
Chen, Zhihong;
Chardon, Florence;
Hill, Andrew J.;
Spurrell, Cailyn;
Ahrendsen, Dakota;
Pietras, Alexander;
Starita, Lea M.;
Hambardzumyan, Dolores;
Iavarone, Antonio;
Shendure, Jay;
Holland, Eric C.

Publication type:

Article

Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples.

Published in:

Glia (0894-1491), 2016, v. 64, n. 8, p. 1416, doi. 10.1002/glia.23014

By:

Szulzewsky, Frank;
Arora, Sonali;
de Witte, Lot;
Ulas, Thomas;
Markovic, Darko;
Schultze, Joachim L.;
Holland, Eric C.;
Synowitz, Michael;
Wolf, Susanne A.;
Kettenmann, Helmut

Publication type:

Article

The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions.

Published in:

Glia (0894-1491), 2014, v. 62, n. 10, p. 1595, doi. 10.1002/glia.22702

By:

Pitter, Kenneth L.;
Tamagno, Ilaria;
Feng, Xi;
Ghosal, Kaushik;
Amankulor, Nduka;
Holland, Eric C.;
Hambardzumyan, Dolores

Publication type:

Article

The brain tumor microenvironment.

Published in:

Glia (0894-1491), 2012, v. 60, n. 3, p. 502, doi. 10.1002/glia.21264

By:

Charles, Nikki A.;
Holland, Eric C.;
Gilbertson, Richard;
Glass, Rainer;
Kettenmann, Helmut

Publication type:

Article

Genetic modeling of gliomas in mice: New tools to tackle old problems.

Published in:

Glia (0894-1491), 2011, v. 59, n. 8, p. 1155, doi. 10.1002/glia.21142

By:

Hambardzumyan, Dolores;
Parada, Luis F.;
Holland, Eric C.;
Charest, Al

Publication type:

Article

Introduction.

Published in:

Glia (0894-1491), 2011, v. 59, n. 8, p. 1133, doi. 10.1002/glia.21192

By:

Holland, Eric C.;
Sontheimer, Harald;
Hambardzumyan, Dolores

Publication type:

Article

The brain tumor microenvironment.

Published in:

Glia (0894-1491), 2011, v. 59, n. 8, p. 1169, doi. 10.1002/glia.21136

By:

Charles, Nikki A.;
Holland, Eric C.;
Gilbertson, Richard;
Glass, Rainer;
Kettenmann, Helmut

Publication type:

Article

HOXD12 defines an age-related aggressive subtype of oligodendroglioma.

Published in:

Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02802-1

By:

Nuechterlein, Nicholas;
Cimino, Sadie;
Shelbourn, Allison;
Ha, Vinny;
Arora, Sonali;
Rajan, Sharika;
Shapiro, Linda G.;
Holland, Eric C.;
Aldape, Kenneth;
McGranahan, Tresa;
Gilbert, Mark R.;
Cimino, Patrick J.

Publication type:

Article

Spatial immune profiling of glioblastoma identifies an inflammatory, perivascular phenotype associated with longer survival.

Published in:

Acta Neuropathologica, 2023, v. 146, n. 4, p. 647, doi. 10.1007/s00401-023-02617-6

By:

Wirsching, Hans-Georg;
Felsberg, Jörg;
Prummer, Michael;
Moisoiu, Vlad;
Lourman, Roxanne;
Hertler, Caroline;
Antonios, Michelle;
Cimino, Patrick J.;
Roth, Patrick;
Gorlia, Thierry;
Prins, Robert M.;
Cloughesy, Timothy;
Wen, Patrick Y.;
Holland, Eric C.;
Reifenberger, Guido;
Weller, Michael

Publication type:

Article

cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 3, p. 603, doi. 10.1007/s00401-020-02127-9

By:

Brat, Daniel J.;
Aldape, Kenneth;
Colman, Howard;
Figrarella-Branger, Dominique;
Fuller, Gregory N.;
Giannini, Caterina;
Holland, Eric C.;
Jenkins, Robert B.;
Kleinschmidt-DeMasters, Bette;
Komori, Takashi;
Kros, Johan M.;
Louis, David N.;
McLean, Catriona;
Perry, Arie;
Reifenberger, Guido;
Sarkar, Chitra;
Stupp, Roger;
van den Bent, Martin J.;
von Deimling, Andreas;
Weller, Michael

Publication type:

Article

cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”.

Published in:

Acta Neuropathologica, 2018, v. 136, n. 5, p. 805, doi. 10.1007/s00401-018-1913-0

By:

Brat, Daniel J.;
Aldape, Kenneth;
Colman, Howard;
Holland, Eric C.;
Louis, David N.;
Jenkins, Robert B.;
Kleinschmidt-DeMasters, B. K.;
Perry, Arie;
Reifenberger, Guido;
Stupp, Roger;
von Deimling, Andreas;
Weller, Michael

Publication type:

Article

Combined VEGFR and MAPK pathway inhibition in angiosarcoma.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88703-9

By:

Wagner, Michael J.;
Lyons, Yasmin A.;
Siedel, Jean H.;
Dood, Robert;
Nagaraja, Archana S.;
Haemmerle, Monika;
Mangala, Lingegowda S.;
Chanana, Pritha;
Lazar, Alexander J.;
Wang, Wei-Lien;
Ravi, Vinod;
Holland, Eric C.;
Sood, Anil K.

Publication type:

Article

YKL-40 and MMP-9 as serum markers for patients with primary central nervous system lymphoma.

Published in:

Annals of Neurology, 2011, v. 70, n. 1, p. 163, doi. 10.1002/ana.22360

By:

Hottinger, Andreas F.;
Iwamoto, Fabio M.;
Karimi, Sasan;
Riedel, Elyn;
Dantis, Jocelynn;
Park, Joseph;
Panageas, Katherine S.;
Lassman, Andrew B.;
Abrey, Lauren E.;
Fleisher, Martin;
Holland, Eric C.;
DeAngelis, Lisa M.;
Hormigo, Adília

Publication type:

Article

MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas.

Published in:

FASEB Journal, 2011, v. 25, n. 12, p. 4138, doi. 10.1096/fj.11-185033

By:

Ruimin Huang;
Cheung, Nai-Kong V.;
Vider, Jelena;
Cheung, Irene Y.;
Gerald, William L.;
Tickoo, Satish K.;
Holland, Eric C.;
Blasberg, Ronald G.

Publication type:

Article

Incorporating genomic signatures into surgical and medical decision-making for elderly glioblastoma patients.

Published in:

Neurosurgical Focus, 2020, v. 49, n. 4, p. 1, doi. 10.3171/2020.7.FOCUS20418

By:

Ene, Chibawanye I.;
Cimino, Patrick J.;
Fine, Howard A.;
Holland, Eric C.

Publication type:

Article

A Mathematical Methodology for Determining the Temporal Order of Pathway Alterations Arising during Gliomagenesis.

Published in:

PLoS Computational Biology, 2012, v. 8, n. 1, p. 1, doi. 10.1371/journal.pcbi.1002337

By:

Cheng, Yu-Kang;
Beroukhim, Rameen;
Levine, Ross L.;
Mellinghoff, Ingo K.;
Holland, Eric C.;
Michor, Franziska

Publication type:

Article

Molecular Pathogenesis of Malignant Glial Tumors.

Published in:

Toxicologic Pathology, 2011, v. 39, n. 1, p. 158, doi. 10.1177/0192623310387617

By:

Jones, Terreia S.;
Holland, Eric C.

Publication type:

Article

A Mouse Model for Glioma: Biology, Pathology, and Therapeutic Opportunities.

Published in:

Toxicologic Pathology, 2000, v. 28, n. 1, p. 171, doi. 10.1177/019262330002800122

By:

Holland, Eric C.

Publication type:

Article

Oncogenic Signaling Is Dominant to Cell of Origin and Dictates Astrocytic or Oligodendroglial Tumor Development from Oligodendrocyte Precursor Cells.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 44, p. 14644, doi. 10.1523/JNEUROSCI.2977-14.2014

By:

Lindberg, Nanna;
Yiwen Jiang;
Yuan Xie;
Bolouri, Hamid;
Kastemar, Marianne;
Olofsson, Tommie;
Holland, Eric C.;
Uhrbom, Lene

Publication type:

Article

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice.

Published in:

Nature Genetics, 2000, v. 25, n. 1, p. 55, doi. 10.1038/75596

By:

Holland, Eric C.;
Celestino, Joseph;
Dai, Chengkai;
Schaefer, Laura;
Sawaya, Raymond E.;
Fuller, Gregory N.

Publication type:

Article

Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma.

Published in:

2010

By:

Huse, Jason T.;
Holland, Eric C.

Publication type:

journal article

Connective Tissue Growth Factor and the Parallels Between Brain Injury and Brain Tumors.

Published in:

JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 15, p. 1141, doi. 10.1093/jnci/djr261

By:

Halliday, John J.;
Holland, Eric C.

Publication type:

Article

EGFR signaling is differentially activated in patient-derived glioblastoma stem cells.

Published in:

Journal of Experimental Therapeutics & Oncology, 2010, v. 8, n. 3, p. 247

By:

Howard, Brian M.;
Gursel, Demirkan B.;
Bleau, Anne-Marie;
Beyene, Robel T.;
Holland, Eric C.;
Boockvar, John A.

Publication type:

Article

Utilizing preclinical models to develop targeted therapies for rare central nervous system cancers.

Published in:

Neuro-Oncology, 2021, v. 23, p. S4, doi. 10.1093/neuonc/noab183

By:

Arakaki, Aleena K S;
Szulzewsky, Frank;
Gilbert, Mark R;
Gujral, Taranjit S;
Holland, Eric C

Publication type:

Article

Anti–PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma.

Published in:

Neuro-Oncology, 2020, v. 22, n. 5, p. 639, doi. 10.1093/neuonc/noz226

By:

Ene, Chibawanye I;
Kreuser, Shannon A;
Jung, Miyeon;
Zhang, Huajia;
Arora, Sonali;
Moyes, Kara White;
Szulzewsky, Frank;
Barber, Jason;
Cimino, Patrick J;
Wirsching, Hans-Georg;
Patel, Anoop;
Kong, Paul;
Woodiwiss, Timothy R;
Durfy, Sharon J;
Houghton, A McGarry;
Pierce, Robert H;
Parney, Ian F;
Crane, Courtney A;
Holland, Eric C

Publication type:

Article

Cooperation of oncolytic virotherapy with VEGF-neutralizing antibody treatment in IDH wildtype glioblastoma depends on MMP9.

Published in:

Neuro-Oncology, 2019, v. 21, n. 12, p. 1607, doi. 10.1093/neuonc/noz145

By:

Wirsching, Hans-Georg;
Arora, Sonali;
Zhang, Huajia;
Szulzewsky, Frank;
Cimino, Patrick J;
Quéva, Christophe;
Houghton, A McGarry;
Glorioso, Joseph C;
Weller, Michael;
Holland, Eric C

Publication type:

Article

Targeted copy number analysis outperforms histologic grading in predicting patient survival for WHO grades II/III IDH-mutant astrocytomas.

Published in:

Neuro-Oncology, 2019, v. 21, n. 6, p. 819, doi. 10.1093/neuonc/noz052

By:

Cimino, Patrick J;
Holland, Eric C

Publication type:

Article

Copy number profiling across glioblastoma populations has implications for clinical trial design.

Published in:

Neuro-Oncology, 2018, v. 20, n. 10, p. 1368, doi. 10.1093/neuonc/noy108

By:

Cimino, Patrick J;
McFerrin, Lisa;
Wirsching, Hans-Georg;
Arora, Sonali;
Bolouri, Hamid;
Rabadan, Raul;
Weller, Michael;
Holland, Eric C

Publication type:

Article

Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment.

Published in:

Neuro-Oncology, 2018, v. 20, n. 3, p. 355, doi. 10.1093/neuonc/nox165

By:

Szulzewsky, Frank;
Schwendinger, Nina;
Güneykaya, Dilansu;
Cimino, Patrick J.;
Hambardzumyan, Dolores;
Synowitz, Michael;
Holland, Eric C.;
Kettenmann, Helmut

Publication type:

Article

Serum YKL-40 is a marker of prognosis and disease status in high-grade gliomas†.

Published in:

Neuro-Oncology, 2011, v. 13, n. 11, p. 1244, doi. 10.1093/neuonc/nor117

By:

Iwamoto, Fabio M.;
Hottinger, Andreas F.;
Karimi, Sasan;
Riedel, Elyn;
Dantis, Jocelynn;
Jahdi, Maryam;
Panageas, Katherine S.;
Lassman, Andrew B.;
Abrey, Lauren E.;
Fleisher, Martin;
DeAngelis, Lisa M.;
Holland, Eric C.;
Hormigo, Adília

Publication type:

Article

Reply: Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.

Published in:

2017

By:

Weller, Michael;
Holland, Eric C;
Hambardzumyan, Dolores

Publication type:

Letter

Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.

Published in:

2017

By:

Klement, Rainer J.;
Champ, Colin E.;
Weller, Michael;
Holland, Eric C.;
Hambardzumyan, Dolores

Publication type:

Letter

Corticosteroids compromise survival in glioblastoma.

Published in:

2016

By:

Pitter, Kenneth L.;
Tamagno, IIaria;
Alikhanyan, Kristina;
Hosni-Ahmed, Amira;
Pattwell, Siobhan S.;
Donnola, Shannon;
Dai, Charles;
Tatsuya Ozawa;
Maria Chang;
Chan, Timothy A.;
Beal, Kathryn;
Bishop, Andrew J.;
Barker, Christopher A.;
Jones, Terreia S.;
Hentschel, Bettina;
Gorlia, Thierry;
Schlegel, Uwe;
Stupp, Roger;
Weller, Michael;
Holland, Eric C.

Publication type:

journal article

CSF-1R inhibition alters macrophage polarization and blocks glioma progression.

Published in:

Nature Medicine, 2013, v. 19, n. 10, p. 1264, doi. 10.1038/nm.3337

By:

Pyonteck, Stephanie M;
Akkari, Leila;
Schuhmacher, Alberto J;
Bowman, Robert L;
Sevenich, Lisa;
Quail, Daniela F;
Olson, Oakley C;
Quick, Marsha L;
Huse, Jason T;
Teijeiro, Virginia;
Setty, Manu;
Leslie, Christina S;
Oei, Yoko;
Pedraza, Alicia;
Zhang, Jianan;
Brennan, Cameron W;
Sutton, James C;
Holland, Eric C;
Daniel, Dylan;
Joyce, Johanna A

Publication type:

Article

A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle.

Published in:

Nature Medicine, 2012, v. 18, n. 5, p. 829, doi. 10.1038/nm.2721

By:

Kircher, Moritz F;
de la Zerda, Adam;
Jokerst, Jesse V;
Zavaleta, Cristina L;
Kempen, Paul J;
Mittra, Erik;
Pitter, Ken;
Huang, Ruimin;
Campos, Carl;
Habte, Frezghi;
Sinclair, Robert;
Brennan, Cameron W;
Mellinghoff, Ingo K;
Holland, Eric C;
Gambhir, Sanjiv S

Publication type:

Article

Molecular imaging of Akt kinase activity.

Published in:

Nature Medicine, 2007, v. 13, n. 9, p. 1114, doi. 10.1038/nm1608

By:

Limin Zhang;
Lee, Kuei C.;
Bhojani, Mahaveer .S;
Khan, Amjad P.;
Shilman, Alla;
Holland, Eric C.;
Ross, Brian D.;
Rehemtulla, Alnawaz

Publication type:

Article

Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model.

Published in:

Nature Medicine, 2004, v. 10, n. 11, p. 1257, doi. 10.1038/nm1120

By:

Uhrbom, Lene;
Nerio, Edward;
Holland, Eric C

Publication type:

Article