Works matching AU Holländer, Georg A

Results: 33

Claudins provide a breath of fresh Aire.

Published in:

Nature Immunology, 2007, v. 8, n. 3, p. 234, doi. 10.1038/ni0307-234

By:

Holländer, Georg A

Publication type:

Article

Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice.

Published in:

Nature Immunology, 2002, v. 3, n. 11, p. 1102, doi. 10.1038/ni850

By:

Balciunaite, Gina;
Keller, Marcel P.;
Balciunaite, Egle;
Piali, Luca;
Zuklys, Saulius;
Mathieu, Yves D.;
Gill, Jason;
Boyd, Richard;
Sussman, Daniel J.;
Holländer, Georg A.

Publication type:

Article

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling.

Published in:

Nature, 2006, v. 444, n. 7120, p. 724, doi. 10.1038/nature05269

By:

Daniels, Mark A.;
Teixeiro, Emma;
Gill, Jason;
Hausmann, Barbara;
Roubaty, Dominique;
Holmberg, Kaisa;
Werlen, Guy;
Holländer, Georg A.;
Gascoigne, Nicholas R. J.;
Palmer, Ed

Publication type:

Article

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02203-0

By:

Oftedal, Bergithe E.;
Maio, Stefano;
Handel, Adam E.;
White, Madeleine P. J.;
Howie, Duncan;
Davis, Simon;
Prevot, Nicolas;
Rota, Ioanna A.;
Deadman, Mary E.;
Kessler, Benedikt M.;
Fischer, Roman;
Trede, Nikolaus S.;
Sezgin, Erdinc;
Maizels, Rick M.;
Holländer, Georg A.

Publication type:

Article

Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24158-w

By:

Barthlott, Thomas;
Handel, Adam E.;
Teh, Hong Ying;
Wirasinha, Rushika C.;
Hafen, Katrin;
Žuklys, Saulius;
Roch, Benoit;
Orkin, Stuart H.;
de Villartay, Jean-Pierre;
Daley, Stephen R.;
Holländer, Georg A.

Publication type:

Article

Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2018.02902

By:

Fergusson, Joannah R.;
Morgan, Michael D.;
Bruchard, Melanie;
Huitema, Leonie;
Heesters, Balthasar A.;
van Unen, Vincent;
van Hamburg, Jan Piet;
van der Wel, Nicole N.;
Picavet, Daisy;
Koning, Frits;
Tas, Sander W.;
Anderson, Mark S.;
Marioni, John C.;
Holländer, Georg A.;
Spits, Hergen

Publication type:

Article

Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02120

By:

Handel, Adam E.;
Shikama-Dorn, Noriko;
Zhanybekova, Saule;
Maio, Stefano;
Graedel, Annina N.;
Zuklys, Saulius;
Ponting, Chris P.;
Holländer, Georg A.

Publication type:

Article

TGF-β type II receptor expression in thymic epithelial cells inhibits the development of Hassall’s corpuscles in mice.

Published in:

International Immunology, 2013, v. 25, n. 11, p. 633, doi. 10.1093/intimm/dxt026

By:

Odaka, Chikako;
Hauri-Hohl, Mathias;
Takizawa, Kazuya;
Nishikawa, Yomiko;
Yano, Masashi;
Matsumoto, Mitsuru;
Boyd, Richard;
Holländer, Georg A.

Publication type:

Article

Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.

Published in:

European Journal of Immunology, 2016, v. 46, n. 4, p. 846, doi. 10.1002/eji.201545995

By:

Mayer, Carlos E.;
Žuklys, Saulius;
Zhanybekova, Saule;
Ohigashi, Izumi;
Teh, Hong‐Ying;
Sansom, Stephen N.;
Shikama‐Dorn, Noriko;
Hafen, Katrin;
Macaulay, Iain C.;
Deadman, Mary E.;
Ponting, Chris P.;
Takahama, Yousuke;
Holländer, Georg A.

Publication type:

Article

A subpopulation of CD103posICOSpos Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage.

Published in:

European Journal of Immunology, 2015, v. 45, n. 6, p. 1760, doi. 10.1002/eji.201445235

By:

Barthlott, Thomas;
Bosch, Angela J. T.;
Berkemeier, Caroline;
Nogales‐Cadenas, Rubén;
Jeker, Lukas T.;
Keller, Marcel P.;
Pascual‐Montano, Alberto;
Holländer, Georg A.

Publication type:

Article

Thymus Extracellular Matrix‐Derived Scaffolds Support Graft‐Resident Thymopoiesis and Long‐Term In Vitro Culture of Adult Thymic Epithelial Cells.

Published in:

Advanced Functional Materials, 2021, v. 31, n. 20, p. 1, doi. 10.1002/adfm.202010747

By:

Asnaghi, M. Adelaide;
Barthlott, Thomas;
Gullotta, Fabiana;
Strusi, Valentina;
Amovilli, Anna;
Hafen, Katrin;
Srivastava, Gitika;
Oertle, Philipp;
Toni, Roberto;
Wendt, David;
Holländer, Georg A.;
Martin, Ivan

Publication type:

Article

The molecular nature of the cystic fibrosis antigen.

Published in:

Nature, 1988, v. 331, n. 6157, p. 570, doi. 10.1038/331570a0

By:

BRüGGEN, JOSEF;
TARCSAY, LAJOS;
CERLETTI, NICO;
ODNIK, KAREL;
RUTISHAUSER, MARKUS;
HOLLÄNDER, GEORG;
SORG, CLEMENS

Publication type:

Article

Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells.

Published in:

EMBO Journal, 2020, v. 39, n. 1, p. N.PAG, doi. 10.15252/embj.2019101828

By:

Dhalla, Fatima;
Baran‐Gale, Jeanette;
Maio, Stefano;
Chappell, Lia;
Holländer, Georg A;
Ponting, Chris P

Publication type:

Article

Cellular and molecular events during early thymus development.

Published in:

Immunological Reviews, 2006, v. 209, n. 1, p. 28, doi. 10.1111/j.0105-2896.2006.00357.x

By:

Holländer, Georg;
Gill, Jason;
Zuklys, Saulius;
Iwanami, Norimasa;
Liu, Cunlan;
Takahama, Yousuke

Publication type:

Article

Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39722-9

By:

Klein, Fabian;
Veiga-Villauriz, Clara;
Börsch, Anastasiya;
Maio, Stefano;
Palmer, Sam;
Dhalla, Fatima;
Handel, Adam E.;
Zuklys, Saulius;
Calvo-Asensio, Irene;
Musette, Lucas;
Deadman, Mary E.;
White, Andrea J.;
Lucas, Beth;
Anderson, Graham;
Holländer, Georg A.

Publication type:

Article

β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis.

Published in:

Nature Medicine, 2002, v. 8, n. 12, p. 1414, doi. 10.1038/nm1202-792

By:

Frigerio, Simona;
Junt, Tobias;
Lu, Bao;
Gerard, Craig;
Zumsteg, Urs;
Holländer, Georg A.;
Piali, Luca

Publication type:

Article

A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla.

Published in:

Nature Immunology, 2014, v. 15, n. 6, p. 554, doi. 10.1038/ni.2869

By:

Hauri-Hohl, Mathias;
Zuklys, Saulius;
Holländer, Georg A;
Ziegler, Steven F

Publication type:

Article

Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny.

Published in:

International Immunology, 1996, v. 8, n. 6, p. 939, doi. 10.1093/intimm/8.6.939

By:

Baoping Wang;
Holländer, Georg A.;
Nichogiannopoulou, Allki;
Simpson, Stephen J.;
Orange, Jordan S.;
Gutierrez-Ramos, Jose-Carlos;
Burakoff, Steven J.;
Biron, Christine A.;
Terhorst, Cox

Publication type:

Article

Phosphatidylinositol 3-Kinase Signaling in Thymocytes: The Need for Stringent Control.

Published in:

Science Signaling, 2010, v. 3, n. 135, p. 1, doi. 10.1126/scisignal.3135re5

By:

Fayard, Elisabeth;
Moncayo, Gerald;
Hemmings, Brian A.;
Holländer, Georg A.

Publication type:

Article

An assessment of the factors affecting the commercialization of cell-based therapeutics: a systematic review protocol.

Published in:

Systematic Reviews, 2017, v. 6, p. 1, doi. 10.1186/s13643-017-0517-4

By:

Pettitt, David;
Arshad, Zeeshaan;
Davies, Benjamin;
Smith, James;
French, Anna;
Cole, Doug;
Bure, Kim;
Dopson, Sue;
DiGiusto, David;
Karp, Jeff;
Reeve, Brock;
Barker, Richard;
Holländer, Georg;
Brindley, David

Publication type:

Article

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00686-2

By:

Qianxin Wu;
Ferry, Quentin R. V.;
Baeumler, Toni A.;
Michaels, Yale S.;
Vitsios, Dimitrios M.;
Habib, Omer;
Arnold, Roland;
Xiaowei Jiang;
Maio, Stefano;
Steinkraus, Bruno R.;
Tapia, Marta;
Piazza, Paolo;
Ni Xu;
Holländer, Georg A.;
Milne, Thomas A.;
Jin-Soo Kim;
Enright, Anton J.;
Bassett, Andrew R.;
Fulga, Tudor A.

Publication type:

Article

CD43 regulates the threshold for T cell activation by targeting Cbl functions.

Published in:

IUBMB Life, 2011, v. 63, n. 10, p. 940, doi. 10.1002/iub.554

By:

Pedraza-Alva, Gustavo;
Mérida, Lilia B.;
del Rio, Roxana;
Fierro, Nora A.;
Cruz-Muñoz, Mario E.;
Olivares, Norma;
Melchy, Erika;
Igras, Vivian;
Holländer, Georg A.;
Burakoff, Steven J.;
Rosenstein, Yvonne

Publication type:

Article

Deficiency of the Metalloproteinase-Disintegrin ADAM8 Is Associated with Thymic Hyper-Cellularity.

Published in:

PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0012766

By:

Gossens, Klaus;
Naus, Silvia;
Holländer, Georg A.;
Ziltener, Hermann J.

Publication type:

Article

Ageing compromises mouse thymus function and remodels epithelial cell differentiation.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.56221

By:

Baran-Gale, Jeanette;
Morgan, Michael D.;
Maio, Stefano;
Dhalla, Fatima;
Calvo-Asensio, Irene;
Deadman, Mary E.;
Handel, Adam E.;
Maynard, Ashley;
Chen, Steven;
Green, Foad;
Sit, Rene V.;
Neff, Norma F.;
Darmanis, Spyros;
Tan, Weilun;
May, Andy P.;
Marioni, John C.;
Ponting, Chris P.;
Holländer, Georg A.

Publication type:

Article

IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4+Foxp3+ regulatory T lymphocytes.

Published in:

Frontiers in Immunology, 2022, v. 12, p. 1, doi. 10.3389/fimmu.2022.965303

By:

Apert, Cécile;
Galindo-Albarrán, Ariel O.;
Castan, Sarah;
Detraves, Claire;
Michaud, Héloise;
McJannett, Nicola;
Haegeman, Bart;
Fillatreau, Simon;
Malissen, Bernard;
Holländer, Georg;
Žuklys, Saulius;
Santamaria, Jérémy C.;
Joffre, Olivier P.;
Romagnoli, Paola;
van Meerwijk, Joost P. M.

Publication type:

Article

Abrogation of Notch Signaling in Embryonic TECs Impacts Postnatal mTEC Homeostasis and Thymic Involution.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.867302

By:

García-León, María Jesús;
Mosquera, Marta;
Cela, Carmela;
Alcain, Juan;
Zuklys, Saulius;
Holländer, Georg;
Toribio, María L.

Publication type:

Article

Cover Picture: Eur. J. Immunol. 2/10.

Published in:

European Journal of Immunology, 2010, v. 40, n. 2, p. n/a, doi. 10.1002/eji.201090005

By:

Saade, Murielle;
Irla, Magali;
Yammine, Miriam;
Boulanger, Nicolas;
Victorero, Geneviève;
Vincentelli, Renaud;
Penninger, Josef M.;
Holländer, Georg A.;
Chauvet, Sophie;
Nguyen, Catherine

Publication type:

Article

Spatial (Tbata) expression in mature medullary thymic epithelial cells.

Published in:

European Journal of Immunology, 2010, v. 40, n. 2, p. 530, doi. 10.1002/eji.200939605

By:

Saade, Murielle;
Irla, Magali;
Yammine, Miriam;
Boulanger, Nicolas;
Victorero, Geneviève;
Vincentelli, Renaud;
Penninger, Josef M.;
Holländer, Georg A.;
Chauvet, Sophie;
Nguyen, Catherine

Publication type:

Article

Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis.

Published in:

European Journal of Immunology, 2010, v. 40, n. 1, p. 81, doi. 10.1002/eji.200839213

By:

Kenins, Linda;
Gill, Jason W.;
Holländer, Georg A.;
Wodnar-Filipowicz, Aleksandra

Publication type:

Article

Expression of pro-inflammatory cytokines by TCRαβ.

Published in:

European Journal of Immunology, 1997, v. 27, n. 1, p. 17, doi. 10.1002/eji.1830270104

By:

Simpson, Stephen J.;
Holländer, Georg A.;
Mizoguchi, Emiko;
Allen, Deborah;
Bhan, Atul K.;
Wang, Baoping;
Terhorst, Cox

Publication type:

Article

Introduction: thymus development and function in health and disease.

Published in:

2021

By:

Holländer, Georg A.

Publication type:

Editorial

Lymphoid reconstitution following hematopoietic stem cell transplantation.

Published in:

2008

By:

Holländer, Georg

Publication type:

Editorial

The immunopathology of thymic GVHD.

Published in:

Seminars in Immunopathology, 2008, v. 30, n. 4, p. 439, doi. 10.1007/s00281-008-0131-6

By:

Krenger, Werner;
Holländer, Georg

Publication type:

Article

Works matching AU Holländer, Georg A

Claudins provide a breath of fresh Aire.

Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice.

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling.

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.

Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2.

Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.

Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development.

TGF-β type II receptor expression in thymic epithelial cells inhibits the development of Hassall’s corpuscles in mice.

Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.

A subpopulation of CD103<sup>pos</sup>ICOS<sup>pos</sup> Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stage.

Thymus Extracellular Matrix‐Derived Scaffolds Support Graft‐Resident Thymopoiesis and Long‐Term In Vitro Culture of Adult Thymic Epithelial Cells.

The molecular nature of the cystic fibrosis antigen.

Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells.

Cellular and molecular events during early thymus development.

Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells.

β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis.

A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla.

Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny.

Phosphatidylinositol 3-Kinase Signaling in Thymocytes: The Need for Stringent Control.

An assessment of the factors affecting the commercialization of cell-based therapeutics: a systematic review protocol.

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.

CD43 regulates the threshold for T cell activation by targeting Cbl functions.

Deficiency of the Metalloproteinase-Disintegrin ADAM8 Is Associated with Thymic Hyper-Cellularity.

Ageing compromises mouse thymus function and remodels epithelial cell differentiation.

IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4<sup>+</sup>Foxp3<sup>+</sup> regulatory T lymphocytes.

Abrogation of Notch Signaling in Embryonic TECs Impacts Postnatal mTEC Homeostasis and Thymic Involution.

Cover Picture: Eur. J. Immunol. 2/10.

Spatial (Tbata) expression in mature medullary thymic epithelial cells.

Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis.

Expression of pro-inflammatory cytokines by TCRαβ.

Introduction: thymus development and function in health and disease.

Lymphoid reconstitution following hematopoietic stem cell transplantation.

The immunopathology of thymic GVHD.