Works by Hoffmann, Ethan

Results: 9

A phase II, randomized, placebo-controlled, double-blind, multi-dose study of SRT2104, a SIRT1 activator, in subjects with type 2 diabetes.

Published in:

British Journal of Clinical Pharmacology, 2014, v. 78, n. 1, p. 69, doi. 10.1111/bcp.12327

By:

Baksi, Arun;
Kraydashenko, Oleg;
Zalevkaya, Alsu;
Stets, Roman;
Elliott, Peter;
Haddad, Jonathan;
Hoffmann, Ethan;
Vlasuk, George P.;
Jacobson, Eric W.

Publication type:

Article

Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3.

Published in:

Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 3, p. 514, doi. 10.1002/pro.50

By:

Jin, Lei;
Galonek, Heidi;
Israelian, Kristine;
Choy, Wendy;
Morrison, Michael;
Xia, Yu;
Wang, Xiaohong;
Xu, Yihua;
Yang, Yuecheng;
Smith, Jesse J.;
Hoffmann, Ethan;
Carney, David P.;
Perni, Robert B.;
Jirousek, Michael R.;
Bemis, Jean E.;
Milne, Jill C.;
Sinclair, David A.;
Westphal, Christoph H.

Publication type:

Article

Allopregnanolone Concentrations in Breast Milk and Plasma from Healthy Volunteers Receiving Brexanolone Injection, With Population Pharmacokinetic Modeling of Potential Relative Infant Dose.

Published in:

2022

By:

Wald, Jeffrey;
Henningsson, Anja;
Hanze, Eva;
Hoffmann, Ethan;
Li, Haihong;
Colquhoun, Helen;
Deligiannidis, Kristina M.

Publication type:

journal article

SAGE-217, A Novel GABA<sub>A</sub> Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies.

Published in:

2020

By:

Hoffmann, Ethan;
Nomikos, George G.;
Kaul, Inder;
Raines, Shane;
Wald, Jeff;
Bullock, Amy;
Sankoh, Abdul J.;
Doherty, James;
Kanes, Stephen J.;
Colquhoun, Helen

Publication type:

journal article

Pharmacological characterization of SAGE‐718, a novel positive allosteric modulator of N‐methyl‐d‐aspartate receptors.

Published in:

British Journal of Pharmacology, 2024, v. 181, n. 7, p. 1028, doi. 10.1111/bph.16235

By:

Beckley, Jacob T.;
Aman, Teresa K.;
Ackley, Michael A.;
Kazdoba, Tatiana M.;
Lewis, Michael C.;
Smith, Anne C.;
Farley, Brandon J.;
Dai, Jing;
Deats, Wayne;
Hoffmann, Ethan;
Robichaud, Albert J.;
Doherty, James J.;
Quirk, Michael C.

Publication type:

Article

Oral tolerance to copolymer 1 in myelin basic protein (MBP) TCR transgenic mice: cross-reactivity with MBP-specific TCR and differential induction of anti-inflammatory cytokines.

Published in:

International Immunology, 2002, v. 14, n. 2, p. 131, doi. 10.1093/intimm/14.2.131

By:

Maron, Ruth;
Slavin, Anthony J.;
Hoffmann, Ethan;
Komagata, Yoshinori;
Weiner, Howard L.

Publication type:

Article

Brexanolone as adjunctive therapy in super-refractory status epilepticus.

Published in:

2017

By:

Rosenthal, Eric S.;
Claassen, Jan;
Wainwright, Mark S.;
Husain, Aatif M.;
Vaitkevicius, Henrikas;
Raines, Shane;
Hoffmann, Ethan;
Colquhoun, Helen;
Doherty, James J.;
Kanes, Stephen J.

Publication type:

journal article

Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 75, n. 1, p. 186, doi. 10.1111/j.1365-2125.2012.04340.x

By:

Hoffmann, Ethan;
Wald, Jeff;
Lavu, Siva;
Roberts, John;
Beaumont, Claire;
Haddad, Jon;
Elliott, Peter;
Westphal, Christoph;
Jacobson, Eric

Publication type:

Article

Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2017, v. 32, n. 2, p. n/a, doi. 10.1002/hup.2576

By:

Kanes, Stephen J.;
Colquhoun, Helen;
Doherty, James;
Raines, Shane;
Hoffmann, Ethan;
Rubinow, David R.;
Meltzer‐Brody, Samantha

Publication type:

Article