OpenURL Connection Search

Select item for more details and to access through your institution.

Sterile triggers drive joint inflammation in TNF‐ and IL‐1β‐dependent mouse arthritis models.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 10, p. 1, doi. 10.15252/emmm.202317691
By:
- Thiran, Alexandra;
- Petta, Ioanna;
- Blancke, Gillian;
- Thorp, Marie;
- Planckaert, Guillaume;
- Jans, Maude;
- Andries, Vanessa;
- Barbry, Korneel;
- Gilis, Elisabeth;
- Coudenys, Julie;
- Hochepied, Tino;
- Vanhove, Christian;
- Gracey, Eric;
- Dumas, Emilie;
- Manuelo, Teddy;
- Josipovic, Ivan;
- van Loo, Geert;
- Elewaut, Dirk;
- Vereecke, Lars
Publication type:
Article
Transgenic mice with a NO-insensitive soluble guanylate cyclase.
Published in:
2007
By:
- Brouckaert, Peter;
- Thoonen, R.;
- Sips, Patrick;
- Buys, Emmanuel;
- Rogge, E.;
- Hochepied, Tino
Publication type:
Abstract
Targeting the NO -- cGMP pathway: phenotyping of NO-insensitive sGCbeta1 H105F knockin mice.
Published in:
2007
By:
- Thoonen, Robrecht;
- Buys, Emmanuel;
- Sips, Patrick;
- Nimmegeers, Sofie;
- Van den Hemel, Maureen;
- Hochepied, Tino;
- Van de Voorde, Johan;
- Brouckaert, Peter
Publication type:
Abstract
Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.
Published in:
2011
By:
- Migliorini, Domenico;
- Bogaerts, Sven;
- Defever, Dieter;
- Vyas, Rajesh;
- Geertrui Denecker;
- Radaelli, Enrico;
- Zwolinska, Aleksandra;
- Depaepe, Vanessa;
- Hochepied, Tino;
- Skarnes, William C.;
- Marine, Jean-Christophe;
- Denecker, Geertrui
Publication type:
journal article
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25944-2
By:
- Hoste, Esther;
- Lecomte, Kim;
- Annusver, Karl;
- Vandamme, Niels;
- Roels, Jana;
- Maschalidi, Sophia;
- Verboom, Lien;
- Vikkula, Hanna-Kaisa;
- Sze, Mozes;
- Van Hove, Lisette;
- Verstaen, Kevin;
- Martens, Arne;
- Hochepied, Tino;
- Saeys, Yvan;
- Ravichandran, Kodi;
- Kasper, Maria;
- van Loo, Geert
Publication type:
Article
Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26061-w
By:
- Thery, Fabien;
- Martina, Lia;
- Asselman, Caroline;
- Zhang, Yifeng;
- Vessely, Madeleine;
- Repo, Heidi;
- Sedeyn, Koen;
- Moschonas, George D.;
- Bredow, Clara;
- Teo, Qi Wen;
- Zhang, Jingshu;
- Leandro, Kevin;
- Eggermont, Denzel;
- De Sutter, Delphine;
- Boucher, Katie;
- Hochepied, Tino;
- Festjens, Nele;
- Callewaert, Nico;
- Saelens, Xavier;
- Dermaut, Bart
Publication type:
Article
Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1.
Published in:
Scientific Reports, 2016, p. 38825, doi. 10.1038/srep38825
By:
- Carceller, Elena;
- Ballegeer, Marlies;
- Deckers, Julie;
- Riccardi, Carlo;
- Bruscoli, Stefano;
- Hochepied, Tino;
- Libert, Claude;
- Pérez, Paloma
Publication type:
Article
Mice Overexpressing β-1,4-Galactosyltransferase I Are Resistant to TNF-Induced Inflammation and DSS-Induced Colitis.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0079883
By:
- Vanhooren, Valerie;
- Vandenbroucke, Roosmarijn E.;
- Dewaele, Sylviane;
- Van Hamme, Evelien;
- Haigh, Jody J.;
- Hochepied, Tino;
- Libert, Claude
Publication type:
Article
A20 controls RANK‐dependent osteoclast formation and bone physiology.
Published in:
EMBO Reports, 2022, v. 23, n. 12, p. 1, doi. 10.15252/embr.202255233
By:
- Martens, Arne;
- Hertens, Pieter;
- Priem, Dario;
- Rinotas, Vagelis;
- Meletakos, Theodore;
- Gennadi, Meropi;
- Van Hove, Lisette;
- Louagie, Els;
- Coudenys, Julie;
- De Muynck, Amélie;
- Gaublomme, Djoere;
- Sze, Mozes;
- van Hengel, Jolanda;
- Catrysse, Leen;
- Hoste, Esther;
- Zajac, Jeffrey D;
- Davey, Rachel A;
- Van Hoorebeke, Luc;
- Hochepied, Tino;
- Bertrand, Mathieu J M
Publication type:
Article
Fibrotic enzymes modulate wound‐induced skin tumorigenesis.
Published in:
EMBO Reports, 2021, v. 22, n. 5, p. 1, doi. 10.15252/embr.202051573
By:
- Van Hove, Lisette;
- Lecomte, Kim;
- Roels, Jana;
- Vandamme, Niels;
- Vikkula, Hanna‐Kaisa;
- Hoorens, Isabelle;
- Ongenae, Katia;
- Hochepied, Tino;
- Donati, Giacomo;
- Saeys, Yvan;
- Quist, Sven R;
- Watt, Fiona M;
- van Loo, Geert;
- Hoste, Esther
Publication type:
Article
MALT1 targeting suppresses CARD14‐induced psoriatic dermatitis in mice.
Published in:
EMBO Reports, 2020, v. 21, n. 7, p. 1, doi. 10.15252/embr.201949237
By:
- Van Nuffel, Elien;
- Staal, Jens;
- Baudelet, Griet;
- Haegman, Mira;
- Driege, Yasmine;
- Hochepied, Tino;
- Afonina, Inna S;
- Beyaert, Rudi
Publication type:
Article
MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01898
By:
- Demeyer, Annelies;
- Skordos, Ioannis;
- Driege, Yasmine;
- Kreike, Marja;
- Hochepied, Tino;
- Baens, Mathijs;
- Staal, Jens;
- Beyaert, Rudi
Publication type:
Article
Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46853-x
By:
- Pieters, Tim;
- T'Sas, Sara;
- Demoen, Lisa;
- Almeida, André;
- Haenebalcke, Lieven;
- Matthijssens, Filip;
- Lemeire, Kelly;
- D'Hont, Jinke;
- Van Rockeghem, Frederique;
- Hochepied, Tino;
- Lintermans, Beatrice;
- Reunes, Lindy;
- Lammens, Tim;
- Berx, Geert;
- Haigh, Jody J.;
- Goossens, Steven;
- Van Vlierberghe, Pieter
Publication type:
Article
The impact of hepatocytespecific deletion of hypoxiainducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1124011
By:
- Vanderhaeghen, Tineke;
- Timmermans, Steven;
- Eggermont, Melanie;
- Watts, Deepika;
- Vandewalle, Jolien;
- Wallaeys, Charlotte;
- Nuyttens, Louise;
- De Temmerman, Joyca;
- Hochepied, Tino;
- Dewaele, Sylviane;
- Berghe, Joke Vanden;
- Sanders, Niek;
- Wielockx, Ben;
- Beyaert, Rudi;
- Libert, Claude
Publication type:
Article
Caspase-14 protects against epidermal UVB photodamage and water loss.
Published in:
Nature Cell Biology, 2007, v. 9, n. 6, p. 666, doi. 10.1038/ncb1597
By:
- Denecker, Geertrui;
- Hoste, Esther;
- Gilbert, Barbara;
- Hochepied, Tino;
- Ovaere, Petra;
- Lippens, Saskia;
- Van den Broecke, Caroline;
- Van Damme, Petra;
- D'Herde, Katharina;
- Hachem, Jean-Pierre;
- Borgonie, Gaetan;
- Presland, Richard B.;
- Schoonjans, Luc;
- Libert, Claude;
- Vandekerckhove, Joël;
- Gevaert, Kris;
- Vandenabeele, Peter;
- Declercq, Wim
Publication type:
Article
Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice.
Published in:
Nature Communications, 2015, v. 6, n. 10, p. 8482, doi. 10.1038/ncomms9482
By:
- Thoonen, Robrecht;
- Cauwels, Anje;
- Decaluwe, Kelly;
- Geschka, Sandra;
- Tainsh, Robert E.;
- Delanghe, Joris;
- Hochepied, Tino;
- De Cauwer, Lode;
- Rogge, Elke;
- Voet, Sofie;
- Sips, Patrick;
- Karas, Richard H.;
- Bloch, Kenneth D.;
- Vuylsteke, Marnik;
- Stasch, Johannes-Peter;
- Van de Voorde, Johan;
- Buys, Emmanuel S.;
- Brouckaert, Peter
Publication type:
Article
A new mouse model to study the role of ectopic Nanos3 expression in cancer.
Published in:
2019
By:
- Andries, Vanessa;
- De Keuckelaere, Evi;
- Staes, Katrien;
- Hochepied, Tino;
- Taminau, Joachim;
- Lemeire, Kelly;
- Birembaut, Philippe;
- Berx, Geert;
- van Roy, Frans
Publication type:
journal article
An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 9, p. 2492, doi. 10.1093/hmg/ddv010
By:
- Van Overbeke, Wouter;
- Wongsantichon, Jantana;
- Everaert, Inge;
- Verhelle, Adriaan;
- Zwaenepoel, Olivier;
- Loonchanta, Anantasak;
- Burtnick, Leslie D.;
- De Ganck, Ariane;
- Hochepied, Tino;
- Haigh, Jody;
- Cuvelier, Claude;
- Derave, Wim;
- Robinson, Robert C.;
- Gettemans, Jan
Publication type:
Article
DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation.
Published in:
Cerebral Cortex, 2018, v. 28, n. 2, p. 493, doi. 10.1093/cercor/bhw384
By:
- De Clercq, Sarah;
- Keruzore, Marc;
- Desmaris, Elodie;
- Pollart, Charlotte;
- Assimacopoulos, Stavroula;
- Preillon, Julie;
- Ascenzo, Sabrina;
- Matson, Clinton K.;
- Lee, Melody;
- Xinsheng Nan;
- Meng Li;
- Yasushi Nakagawa;
- Hochepied, Tino;
- Zarkower, David;
- Grove, Elizabeth A.;
- Bellefroid, Eric J.
Publication type:
Article
OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection.
Published in:
Cell Death & Disease, 2023, v. 14, n. 8, p. 1, doi. 10.1038/s41419-023-06058-7
By:
- Verboom, Lien;
- Anderson, Christopher J.;
- Jans, Maude;
- Petta, Ioanna;
- Blancke, Gillian;
- Martens, Arne;
- Sze, Mozes;
- Hochepied, Tino;
- Ravichandran, Kodi S.;
- Vereecke, Lars;
- van Loo, Geert
Publication type:
Article
Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders RESPONSE OF SPRET/Ei TO ARTHRITIS, IBD, AND ASTHMA.
Published in:
Mammalian Genome, 2004, v. 15, n. 7, p. 537, doi. 10.1007/s00335-004-3002-z
By:
- Staelens, Jan;
- Puimège, Leen;
- Mahieu, Tina;
- Pynaert, Gwenda;
- Hochepied, Tino;
- Vandenabeele, Annelies;
- Grooten, Johan;
- Kontoyiannis, Dimitris;
- van Roy, Frans;
- Kollias, George;
- Libert, Claude
Publication type:
Article
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.
Published in:
Acta Neuropathologica, 2018, v. 135, n. 1, p. 131, doi. 10.1007/s00401-017-1756-0
By:
- Bouhy, Delphine;
- Juneja, Manisha;
- Katona, Istvan;
- Holmgren, Anne;
- Asselbergh, Bob;
- De Winter, Vicky;
- Hochepied, Tino;
- Goossens, Steven;
- Haigh, Jody J.;
- Libert, Claude;
- Groote, Chantal Ceuterick-de;
- Irobi, Joy;
- Weis, Joachim;
- Timmerman, Vincent
Publication type:
Article
Innovative mouse models for the tumor suppressor activity of Protocadherin-10 isoforms.
Published in:
2022
By:
- Kleinberger, Irene;
- Sanders, Ellen;
- Staes, Katrien;
- Van Troys, Marleen;
- Hirano, Shinji;
- Hochepied, Tino;
- Lemeire, Kelly;
- Martens, Liesbet;
- Ampe, Christophe;
- van Roy, Frans
Publication type:
journal article
Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45324-8
By:
- Van Damme, Karel F. A.;
- Hertens, Pieter;
- Martens, Arne;
- Gilis, Elisabeth;
- Priem, Dario;
- Bruggeman, Inge;
- Fossoul, Amelie;
- Declercq, Jozefien;
- Aegerter, Helena;
- Wullaert, Andy;
- Hochepied, Tino;
- Hoste, Esther;
- Vande Walle, Lieselotte;
- Lamkanfi, Mohamed;
- Savvides, Savvas N.;
- Elewaut, Dirk;
- Lambrecht, Bart N.;
- van Loo, Geert
Publication type:
Article
Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45324-8
By:
- Van Damme, Karel F. A.;
- Hertens, Pieter;
- Martens, Arne;
- Gilis, Elisabeth;
- Priem, Dario;
- Bruggeman, Inge;
- Fossoul, Amelie;
- Declercq, Jozefien;
- Aegerter, Helena;
- Wullaert, Andy;
- Hochepied, Tino;
- Hoste, Esther;
- Vande Walle, Lieselotte;
- Lamkanfi, Mohamed;
- Savvides, Savvas N.;
- Elewaut, Dirk;
- Lambrecht, Bart N.;
- van Loo, Geert
Publication type:
Article
Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45324-8
By:
- Van Damme, Karel F. A.;
- Hertens, Pieter;
- Martens, Arne;
- Gilis, Elisabeth;
- Priem, Dario;
- Bruggeman, Inge;
- Fossoul, Amelie;
- Declercq, Jozefien;
- Aegerter, Helena;
- Wullaert, Andy;
- Hochepied, Tino;
- Hoste, Esther;
- Walle, Lieselotte Vande;
- Lamkanfi, Mohamed;
- Savvides, Savvas N.;
- Elewaut, Dirk;
- Lambrecht, Bart N.;
- van Loo, Geert
Publication type:
Article
p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification.
Published in:
PLoS Genetics, 2016, v. 12, n. 8, p. 1, doi. 10.1371/journal.pgen.1006243
By:
- Pieters, Tim;
- Goossens, Steven;
- Haenebalcke, Lieven;
- Andries, Vanessa;
- Stryjewska, Agata;
- De Rycke, Riet;
- Lemeire, Kelly;
- Hochepied, Tino;
- Huylebroeck, Danny;
- Berx, Geert;
- Stemmler, Marc P.;
- Wirth, Dagmar;
- Haigh, Jody J.;
- van Hengel, Jolanda;
- van Roy, Frans
Publication type:
Article

Found: 27