Works by Hocek, Michal

Results: 96

ABNOH‐Linked Nucleotides and DNA for Bioconjugation and Cross‐linking with Tryptophan‐Containing Peptides and Proteins.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 49, p. 1, doi. 10.1002/chem.202402151

By:

Spampinato, Ambra;
Leone, Denise‐Liu';
Pohl, Radek;
Tarábek, Ján;
Šoltysová, Markéta;
Polák, Marek;
Kádek, Alan;
Sýkorová, Veronika;
Řezáčová, Pavlína;
Hocek, Michal

Publication type:

Article

Glyco‐DNA: Enzymatic Synthesis of Base‐Modified and Hypermodified DNA Displaying up to Four Different Monosaccharide Units in the Major Groove.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 48, p. 1, doi. 10.1002/chem.202402318

By:

Krömer, Matouš;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Glucosylated 5‐Hydroxymethylpyrimidines as Epigenetic DNA Bases Regulating Transcription and Restriction Cleavage.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 31, p. 1, doi. 10.1002/chem.202200911

By:

Chakrapani, Aswathi;
Ruiz‐Larrabeiti, Olatz;
Pohl, Radek;
Svoboda, Martin;
Krásný, Libor;
Hocek, Michal

Publication type:

Article

Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins.

Published in:

Angewandte Chemie, 2013, v. 125, n. 40, p. 10709, doi. 10.1002/ange.201303577

By:

Dadová, Jitka;
Orság, Petr;
Pohl, Radek;
Brázdová, Marie;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

Transient and Switchable (Triethylsilyl)ethynyl Protection of DNA against Cleavage by Restriction Endonucleases.

Published in:

Angewandte Chemie, 2011, v. 123, n. 37, p. 8886, doi. 10.1002/ange.201102898

By:

Kielkowski, Pavel;
Macíčková-Cahová, Hana;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Direct Polymerase Synthesis of Reactive Aldehyde-Functionalized DNA and Its Conjugation and Staining with Hydrazines.

Published in:

Angewandte Chemie, 2010, v. 122, n. 6, p. 1082, doi. 10.1002/ange.200905556

By:

Raindlová, Veronika;
Pohl, Radek;
Šanda, Miloslav;
Hocek, Michal

Publication type:

Article

Covalent Analogues of Nucleobase-Pairs.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 775, doi. 10.1081/NCN-120022632

By:

Hocek, Michal;
Dvořák, Dalimil;
Havelková, Martina

Publication type:

Article

Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 22, p. 7612

By:

Macíčková-Cahová, Hana;
Hocek, Michal

Publication type:

Article

Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47444-9

By:

Brunderová, Mária;
Havlíček, Vojtěch;
Matyašovský, Ján;
Pohl, Radek;
Poštová Slavětínská, Lenka;
Krömer, Matouš;
Hocek, Michal

Publication type:

Article

Real‐time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA‐Incorporated Thiazole Orange‐Modified Nucleotides.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 38, p. 1, doi. 10.1002/anie.202307548

By:

Kuba, Miroslav;
Khoroshyy, Petro;
Lepšík, Martin;
Kužmová, Erika;
Kodr, David;
Kraus, Tomáš;
Hocek, Michal

Publication type:

Article

Chloroacetamide‐Modified Nucleotide and RNA for Bioconjugations and Cross‐Linking with RNA‐Binding Proteins.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 7, p. 1, doi. 10.1002/anie.202213764

By:

Brunderová, Mária;
Krömer, Matouš;
Vlková, Marta;
Hocek, Michal

Publication type:

Article

1,3‐Diketone‐Modified Nucleotides and DNA for Cross‐Linking with Arginine‐Containing Peptides and Proteins.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 32, p. 17383, doi. 10.1002/anie.202105126

By:

Leone, Denise‐Liu';
Hubálek, Martin;
Pohl, Radek;
Sýkorová, Veronika;
Hocek, Michal

Publication type:

Article

Squaramate‐Modified Nucleotides and DNA for Specific Cross‐Linking with Lysine‐Containing Peptides and Proteins.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 38, p. 13345, doi. 10.1002/anie.201906737

By:

Ivancová, Ivana;
Pohl, Radek;
Hubálek, Martin;
Hocek, Michal

Publication type:

Article

Celebrating Czech Chemistry.

Published in:

ChemPlusChem, 2021, v. 86, n. 1, p. 10, doi. 10.1002/cplu.202000741

By:

Hocek, Michal

Publication type:

Article

2‐Formyl‐dATP as Substrate for Polymerase Synthesis of Reactive DNA Bearing an Aldehyde Group in the Minor Groove.

Published in:

ChemPlusChem, 2020, v. 85, n. 6, p. 1164, doi. 10.1002/cplu.202000287

By:

Krömer, Matouš;
Brunderová, Mária;
Ivancová, Ivana;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Cover Feature: Institute Feature: IOCB Prague (Eur. J. Org. Chem. 37/2018).

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 37, p. 5075, doi. 10.1002/ejoc.201801330

By:

Hocek, Michal;
Hostomský, Zdeněk

Publication type:

Article

Front Cover: Institute Feature: IOCB Prague (Eur. J. Org. Chem. 37/2018).

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 37, p. 5074, doi. 10.1002/ejoc.201801329

By:

Hocek, Michal;
Hostomský, Zdeněk

Publication type:

Article

Isomeric Naphtho‐Fused 7‐Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 37, p. 5092, doi. 10.1002/ejoc.201800165

By:

Ghosh, Ketaki;
Perlíková, Pavla;
Havlíček, Vojtěch;
Yang, Chao;
Pohl, Radek;
Tloušťová, Eva;
Hodek, Jan;
Gurská, Soňa;
Džubák, Petr;
Hajdúch, Marián;
Hocek, Michal

Publication type:

Article

Modification of Pyrrolo[2,3- d]pyrimidines by C-H Borylation Followed by Cross-Coupling or Other Transformations: Synthesis of 6,8-Disubstituted 7-Deazapurine Bases.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 36, p. 7943, doi. 10.1002/ejoc.201501177

By:

Klečka, Martin;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Synthesis of Benzene and Pyridine 2′- C-Methyl- C-ribonucleosides and -nucleotides.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 36, p. 7962, doi. 10.1002/ejoc.201501219

By:

Tokarenko, Anna;
Poštová Slavětínská, Lenka;
Klepetářová, Blanka;
Hocek, Michal

Publication type:

Article

Chemoselective Synthesis of 4,5-Diarylpyrrolo[2,3- d]pyrimidines (6,7-Diaryl-7-deazapurines) by Consecutive Suzuki and Liebeskind-Srogl Cross-Couplings.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 32, p. 7203, doi. 10.1002/ejoc.201402882

By:

Krömer, Matouš;
Klečka, Martin;
Slavětínská, Lenka;
Klepetářová, Blanka;
Hocek, Michal

Publication type:

Article

Synthesis of Substituted Benzyl Homo- C-Ribonucleosides and -Nucleotides as Carba Analogues of Phosphoribosylanthranilate.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 26, p. 4969, doi. 10.1002/ejoc.201200819

By:

Kubelka, Tomáš;
Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Synthesis of 6-Substituted 2(1 H)-Pyridon-3-yl C-2′-Deoxyribonucleosides.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 9, p. 1759, doi. 10.1002/ejoc.201101662

By:

Chapuis, Hubert;
Kubelka, Tomáš;
Joubert, Nicolas;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine Nucleobases.

Published in:

ChemBioChem, 2015, v. 16, n. 15, p. 2225, doi. 10.1002/cbic.201500315

By:

Mačková, Michaela;
Boháčová, Soňa;
Perlíková, Pavla;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Polymerase Synthesis of DNAs Bearing Vinyl Groups in the Major Groove and their Cleavage by Restriction Endonucleases.

Published in:

ChemBioChem, 2014, v. 15, n. 15, p. 2306, doi. 10.1002/cbic.201402319

By:

Mačková, Michaela;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Nucleobase Protection Strategy for Gene Cloning and Expression.

Published in:

ChemBioChem, 2013, v. 14, n. 7, p. 801, doi. 10.1002/cbic.201300127

By:

Kielkowski, Pavel;
Brock, Nelson L.;
Dickschat, Jeroen S.;
Hocek, Michal

Publication type:

Article

Cleavage of Functionalized DNA Containing 5-Modified Pyrimidines by Type II Restriction Endonucleases.

Published in:

ChemBioChem, 2011, v. 12, n. 3, p. 431, doi. 10.1002/cbic.201000644

By:

Macíčková-Cahová, Hana;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Optimization of the Pyridyl Nucleobase Scaffold for Polymerase Recognition and Unnatural Base Pair Replication.

Published in:

ChemBioChem, 2008, v. 9, n. 17, p. 2796, doi. 10.1002/cbic.200800577

By:

Hari, Yoshiyuki;
Hwang, Gil Tae;
Leconte, Aaron M.;
Joubert, Nicolas;
Hocek, Michal;
Romesberg, Floyd E.

Publication type:

Article

Addendum: Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases.

Published in:

2024

By:

Brunderová, Mária;
Havlíček, Vojtěch;
Matyašovský, Ján;
Pohl, Radek;
Poštová Slavětínská, Lenka;
Krömer, Matouš;
Hocek, Michal

Publication type:

Correction Notice

Purines Bearing Phenanthroline or Bipyridine Ligands and Their RuII Complexes in Position 8 as Model Compounds for Electrochemical DNA Labelin – Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antiviral Activity

Published in:

European Journal of Inorganic Chemistry, 2007, v. 2007, n. 12, p. 1752

By:

Milan Vrábel;
Michal Hocek;
Luděk Havran;
Miroslav Fojta;
Ivan Votruba;
Blanka Klepetářová;
Radek Pohl;
Lubomír Rulíšek;
Lucie Zendlová;
Pavel Hobza;
I-hung Shih;
Eric Mabery;
Richard Mackman

Publication type:

Article

2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 51, p. 15856, doi. 10.1002/anie.201609007

By:

Matyašovský, Ján;
Perlíková, Pavla;
Malnuit, Vincent;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

A Rotational BODIPY Nucleotide: An Environment-Sensitive Fluorescence-Lifetime Probe for DNA Interactions and Applications in Live-Cell Microscopy.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 1, p. 174, doi. 10.1002/anie.201507922

By:

Dziuba, Dmytro;
Jurkiewicz, Piotr;
Cebecauer, Marek;
Hof, Martin;
Hocek, Michal

Publication type:

Article

7-Aryl-7-deazaadenine 2′-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 29, p. 7552, doi. 10.1002/anie.201404742

By:

Kielkowski, Pavel;
Fanfrlík, Jindřich;
Hocek, Michal

Publication type:

Article

Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 26, p. 6734, doi. 10.1002/anie.201402370

By:

Vaníková, Zuzana;
Hocek, Michal

Publication type:

Article

Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 40, p. 10515, doi. 10.1002/anie.201303577

By:

Dadová, Jitka;
Orság, Petr;
Pohl, Radek;
Brázdová, Marie;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

Polymerase Synthesis of DNA Containing Iodinated Pyrimidine or 7‐Deazapurine Nucleobases and Their Post‐synthetic Modifications through the Suzuki‐Miyaura Cross‐Coupling Reactions.

Published in:

ChemBioChem, 2022, v. 23, n. 3, p. 1, doi. 10.1002/cbic.202100608

By:

Sýkorová, Veronika;
Tichý, Michal;
Hocek, Michal

Publication type:

Article

Oxidative DNA Cleavage with Clip‐Phenanthroline Triplex‐Forming Oligonucleotide Hybrids.

Published in:

ChemBioChem, 2020, v. 21, n. 7, p. 991, doi. 10.1002/cbic.201900670

By:

Panattoni, Alessandro;
El‐Sagheer, Afaf H.;
Brown, Tom;
Kellett, Andrew;
Hocek, Michal

Publication type:

Article

Vicinal Diol‐Tethered Nucleobases as Targets for DNA Redox Labeling with Osmate Complexes.

Published in:

ChemBioChem, 2020, v. 21, n. 1/2, p. 171, doi. 10.1002/cbic.201900388

By:

Havranová‐Vidláková, Pavlína;
Krömer, Matouš;
Sýkorová, Veronika;
Trefulka, Mojmír;
Fojta, Miroslav;
Havran, Luděk;
Hocek, Michal

Publication type:

Article

Synthesis and Biological Activity of 2,6‐Disubstituted 7‐Deazapurine Ribonucleosides.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 5, p. 1, doi. 10.1002/ejoc.202401187

By:

Šinkevičiūtė, Ugnė;
Dvořáková, Marcela;
Tichý, Michal;
Gurská, Soňa;
Ječmeňová, Kateřina;
Poštová Slavětínská, Lenka;
Džubák, Petr;
Hajdúch, Marián;
Hocek, Michal

Publication type:

Article

Synthesis and Biological Profiling of Benzofuro‐Fused 7‐Deazapurine Nucleosides.

Published in:

European Journal of Organic Chemistry, 2023, v. 26, n. 44, p. 1, doi. 10.1002/ejoc.202300723

By:

Yang, Chao;
Tichý, Michal;
Poštová Slavětínská, Lenka;
Vaiedelich, Enzo;
Gurská, Soňa;
Džubák, Petr;
Hajdúch, Marián;
Hocek, Michal

Publication type:

Article

Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6‐(Thiophen‐2‐yl)‐7‐fluoro‐7‐deazapurine.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 31/32, p. 5409, doi. 10.1002/ejoc.201900509

By:

Malnuit, Vincent;
Smoleń, Sabina;
Tichý, Michal;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

Published in:

ChemMedChem, 2015, v. 10, n. 6, p. 1079, doi. 10.1002/cmdc.201500081

By:

Malnuit, Vincent;
Slavětínská, Lenka Poštová;
Nauš, Petr;
Džubák, Petr;
Hajdúch, Marián;
Stolaříková, Jiřina;
Snášel, Jan;
Pichová, Iva;
Hocek, Michal

Publication type:

Article

Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines.

Published in:

ChemMedChem, 2013, v. 8, n. 5, p. 832, doi. 10.1002/cmdc.201300047

By:

Perlíková, Pavla;
Eberlin, Ludovic;
Ménová, Petra;
Raindlová, Veronika;
Slavětínská, Lenka;
Tloušťová, Eva;
Bahador, Gina;
Lee, Yu‐Jen;
Hocek, Michal

Publication type:

Article

Ferrocene-Modified Purines as Potential Electrochemical Markers: Synthesis, Crystal Structures, Electrochemistry and Cytostatic Activity of (Ferrocenylethynyl)- and (Ferrocenylethyl)purines.

Published in:

Chemistry - A European Journal, 2004, v. 10, n. 8, p. 2058, doi. 10.1002/chem.200305621

By:

Michal Hocek;
Petr Štěpnička;
Jiří Ludvík;
Ivana Císařová;
Ivan Votruba

Publication type:

Article

Squaramate‐Modified Nucleotides and DNA for Specific Cross‐Linking with Lysine‐Containing Peptides and Proteins.

Published in:

Angewandte Chemie, 2019, v. 131, n. 38, p. 13479, doi. 10.1002/ange.201906737

By:

Ivancová, Ivana;
Pohl, Radek;
Hubálek, Martin;
Hocek, Michal

Publication type:

Article

2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove.

Published in:

Angewandte Chemie, 2016, v. 128, n. 51, p. 16088, doi. 10.1002/ange.201609007

By:

Matyašovský, Ján;
Perlíková, Pavla;
Malnuit, Vincent;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

A Rotational BODIPY Nucleotide: An Environment-Sensitive Fluorescence-Lifetime Probe for DNA Interactions and Applications in Live-Cell Microscopy.

Published in:

Angewandte Chemie, 2016, v. 128, n. 1, p. 182, doi. 10.1002/ange.201507922

By:

Dziuba, Dmytro;
Jurkiewicz, Piotr;
Cebecauer, Marek;
Hof, Martin;
Hocek, Michal

Publication type:

Article

7-Aryl-7-deazaadenine 2′-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations.

Published in:

Angewandte Chemie, 2014, v. 126, n. 29, p. 7682, doi. 10.1002/ange.201404742

By:

Kielkowski, Pavel;
Fanfrlík, Jindřich;
Hocek, Michal

Publication type:

Article

Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases.

Published in:

Angewandte Chemie, 2014, v. 126, n. 26, p. 6852, doi. 10.1002/ange.201402370

By:

Vaníková, Zuzana;
Hocek, Michal

Publication type:

Article

Transient and Switchable (Triethylsilyl)ethynyl Protection of DNA against Cleavage by Restriction Endonucleases.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 37, p. 8727, doi. 10.1002/anie.201102898

By:

Kielkowski, Pavel;
Macíčková-Cahová, Hana;
Pohl, Radek;
Hocek, Michal

Publication type:

Article