Works matching AU Hocek, Michal

Results: 96

Glucosylated 5‐Hydroxymethylpyrimidines as Epigenetic DNA Bases Regulating Transcription and Restriction Cleavage.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 31, p. 1, doi. 10.1002/chem.202200911

By:

Chakrapani, Aswathi;
Ruiz‐Larrabeiti, Olatz;
Pohl, Radek;
Svoboda, Martin;
Krásný, Libor;
Hocek, Michal

Publication type:

Article

Glyoxal‐Linked Nucleotides and DNA for Bioconjugations and Crosslinking with Arginine‐Containing Peptides and Proteins.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 14, p. 1, doi. 10.1002/chem.202104208

By:

Leone, Denise‐Liu';
Pohl, Radek;
Hubálek, Martin;
Kadeřábková, Marta;
Krömer, Matouš;
Sýkorová, Veronika;
Hocek, Michal

Publication type:

Article

Acetophenyl‐thienyl‐aniline‐Linked Nucleotide for Construction of Solvatochromic Fluorescence Light‐Up DNA Probes Sensing Protein‐DNA Interactions.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 24, p. 7090, doi. 10.1002/chem.202100575

By:

Güixens‐Gallardo, Pedro;
Hocek, Michal

Publication type:

Article

Synthesis and Cytotoxic and Antiviral Activity Profiling of All‐Four Isomeric Series of Pyrido‐Fused 7‐Deazapurine Ribonucleosides.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 57, p. 13002, doi. 10.1002/chem.202001124

By:

Veselovská, Lucia;
Kudlová, Natálie;
Gurská, Soňa;
Lišková, Barbora;
Medvedíková, Martina;
Hodek, Ondřej;
Tloušťová, Eva;
Milisavljevic, Nemanja;
Tichý, Michal;
Perlíková, Pavla;
Mertlíková‐Kaiserová, Helena;
Trylčová, Jana;
Pohl, Radek;
Klepetářová, Blanka;
Džubák, Petr;
Hajdúch, Marián;
Hocek, Michal

Publication type:

Article

Cover Feature: Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions (Chem. Eur. J. 52/2020).

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 52, p. 11911, doi. 10.1002/chem.202003781

By:

Kuba, Miroslav;
Kraus, Tomáš;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 52, p. 11950, doi. 10.1002/chem.202003192

By:

Kuba, Miroslav;
Kraus, Tomáš;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Cover Feature: Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labeling and Coding of Nucleotides and DNA (Chem. Eur. J. 6/2020).

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 6, p. 1162, doi. 10.1002/chem.201905443

By:

Simonova, Anna;
Magriñá, Ivan;
Sýkorová, Veronika;
Pohl, Radek;
Ortiz, Mayreli;
Havran, Luděk;
Fojta, Miroslav;
O'Sullivan, Ciara K.;
Hocek, Michal

Publication type:

Article

Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labeling and Coding of Nucleotides and DNA.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 6, p. 1286, doi. 10.1002/chem.201904700

By:

Simonova, Anna;
Magriñá, Ivan;
Sýkorová, Veronika;
Pohl, Radek;
Ortiz, Mayreli;
Havran, Luděk;
Fojta, Miroslav;
O'Sullivan, Ciara K.;
Hocek, Michal

Publication type:

Article

A Rotational BODIPY Nucleotide: An Environment-Sensitive Fluorescence-Lifetime Probe for DNA Interactions and Applications in Live-Cell Microscopy.

Published in:

Angewandte Chemie, 2016, v. 128, n. 1, p. 182, doi. 10.1002/ange.201507922

By:

Dziuba, Dmytro;
Jurkiewicz, Piotr;
Cebecauer, Marek;
Hof, Martin;
Hocek, Michal

Publication type:

Article

7-Aryl-7-deazaadenine 2′-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations.

Published in:

Angewandte Chemie, 2014, v. 126, n. 29, p. 7682, doi. 10.1002/ange.201404742

By:

Kielkowski, Pavel;
Fanfrlík, Jindřich;
Hocek, Michal

Publication type:

Article

Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases.

Published in:

Angewandte Chemie, 2014, v. 126, n. 26, p. 6852, doi. 10.1002/ange.201402370

By:

Vaníková, Zuzana;
Hocek, Michal

Publication type:

Article

Vinylsulfonamide and Acrylamide Modification of DNA for Cross-linking with Proteins.

Published in:

Angewandte Chemie, 2013, v. 125, n. 40, p. 10709, doi. 10.1002/ange.201303577

By:

Dadová, Jitka;
Orság, Petr;
Pohl, Radek;
Brázdová, Marie;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

Transient and Switchable (Triethylsilyl)ethynyl Protection of DNA against Cleavage by Restriction Endonucleases.

Published in:

Angewandte Chemie, 2011, v. 123, n. 37, p. 8886, doi. 10.1002/ange.201102898

By:

Kielkowski, Pavel;
Macíčková-Cahová, Hana;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Pyrrolo[2,3- d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.

Published in:

Medicinal Research Reviews, 2017, v. 37, n. 6, p. 1429, doi. 10.1002/med.21465

By:

Perlíková, Pavla;
Hocek, Michal

Publication type:

Article

Cover Feature: Institute Feature: IOCB Prague (Eur. J. Org. Chem. 37/2018).

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 37, p. 5075, doi. 10.1002/ejoc.201801330

By:

Hocek, Michal;
Hostomský, Zdeněk

Publication type:

Article

Front Cover: Institute Feature: IOCB Prague (Eur. J. Org. Chem. 37/2018).

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 37, p. 5074, doi. 10.1002/ejoc.201801329

By:

Hocek, Michal;
Hostomský, Zdeněk

Publication type:

Article

Isomeric Naphtho‐Fused 7‐Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 37, p. 5092, doi. 10.1002/ejoc.201800165

By:

Ghosh, Ketaki;
Perlíková, Pavla;
Havlíček, Vojtěch;
Yang, Chao;
Pohl, Radek;
Tloušťová, Eva;
Hodek, Jan;
Gurská, Soňa;
Džubák, Petr;
Hajdúch, Marián;
Hocek, Michal

Publication type:

Article

Modification of Pyrrolo[2,3- d]pyrimidines by C-H Borylation Followed by Cross-Coupling or Other Transformations: Synthesis of 6,8-Disubstituted 7-Deazapurine Bases.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 36, p. 7943, doi. 10.1002/ejoc.201501177

By:

Klečka, Martin;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Synthesis of Benzene and Pyridine 2′- C-Methyl- C-ribonucleosides and -nucleotides.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 36, p. 7962, doi. 10.1002/ejoc.201501219

By:

Tokarenko, Anna;
Poštová Slavětínská, Lenka;
Klepetářová, Blanka;
Hocek, Michal

Publication type:

Article

Chemoselective Synthesis of 4,5-Diarylpyrrolo[2,3- d]pyrimidines (6,7-Diaryl-7-deazapurines) by Consecutive Suzuki and Liebeskind-Srogl Cross-Couplings.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 32, p. 7203, doi. 10.1002/ejoc.201402882

By:

Krömer, Matouš;
Klečka, Martin;
Slavětínská, Lenka;
Klepetářová, Blanka;
Hocek, Michal

Publication type:

Article

Synthesis of Substituted Benzyl Homo- C-Ribonucleosides and -Nucleotides as Carba Analogues of Phosphoribosylanthranilate.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 26, p. 4969, doi. 10.1002/ejoc.201200819

By:

Kubelka, Tomáš;
Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Synthesis of 6-Substituted 2(1 H)-Pyridon-3-yl C-2′-Deoxyribonucleosides.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 9, p. 1759, doi. 10.1002/ejoc.201101662

By:

Chapuis, Hubert;
Kubelka, Tomáš;
Joubert, Nicolas;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Direct Polymerase Synthesis of Reactive Aldehyde-Functionalized DNA and Its Conjugation and Staining with Hydrazines.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 6, p. 1064, doi. 10.1002/anie.200905556

By:

Raindlová, Veronika;
Pohl, Radek;
Šanda, Miloslav;
Hocek, Michal

Publication type:

Article

Aminophenyl- and Nitrophenyl-Labeled Nucleoside Triphosphates: Synthesis, Enzymatic Incorporation, and Electrochemical Detection.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 11, p. 2059, doi. 10.1002/anie.200705088

By:

Cahová, Hana;
Havran, Luděk;
Brázdilová, Petra;
Pivoňková, Hana;
Pohl, Radek;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

2‐Allyl‐ and Propargylamino‐dATPs for Site‐Specific Enzymatic Introduction of a Single Modification in the Minor Groove of DNA.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 56, p. 14938, doi. 10.1002/chem.201803973

By:

Matyašovský, Ján;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Cover Feature: Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations (Chem. Eur. J. 46/2018).

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 46, p. 11804, doi. 10.1002/chem.201803253

By:

Krömer, Matouš;
Bártová, Kateřina;
Raindlová, Veronika;
Hocek, Michal

Publication type:

Article

Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 46, p. 11890, doi. 10.1002/chem.201802282

By:

Krömer, Matouš;
Bártová, Kateřina;
Raindlová, Veronika;
Hocek, Michal

Publication type:

Article

Turning Off Transcription with Bacterial RNA Polymerase through CuAAC Click Reactions of DNA Containing 5‐Ethynyluracil.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 33, p. 8311, doi. 10.1002/chem.201801757

By:

Slavíčková, Michaela;
Janoušková, Martina;
Šimonová, Anna;
Cahová, Hana;
Kambová, Milada;
Šanderová, Hana;
Krásný, Libor;
Hocek, Michal

Publication type:

Article

Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5- O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 16, p. 3910, doi. 10.1002/chem.201604955

By:

Downey, A. Michael;
Pohl, Radek;
Roithová, Jana;
Hocek, Michal

Publication type:

Article

Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 45, p. 16091, doi. 10.1002/chem.201502209

By:

Dadová, Jitka;
Vrábel, Milan;
Adámik, Matej;
Brázdová, Marie;
Pohl, Radek;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

Covalent Analogues of Nucleobase-Pairs.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 775, doi. 10.1081/NCN-120022632

By:

Hocek, Michal;
Dvořák, Dalimil;
Havelková, Martina

Publication type:

Article

Synthesis and Biological Activity of 2,6‐Disubstituted 7‐Deazapurine Ribonucleosides.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 5, p. 1, doi. 10.1002/ejoc.202401187

By:

Šinkevičiūtė, Ugnė;
Dvořáková, Marcela;
Tichý, Michal;
Gurská, Soňa;
Ječmeňová, Kateřina;
Poštová Slavětínská, Lenka;
Džubák, Petr;
Hajdúch, Marián;
Hocek, Michal

Publication type:

Article

Synthesis and Biological Profiling of Benzofuro‐Fused 7‐Deazapurine Nucleosides.

Published in:

European Journal of Organic Chemistry, 2023, v. 26, n. 44, p. 1, doi. 10.1002/ejoc.202300723

By:

Yang, Chao;
Tichý, Michal;
Poštová Slavětínská, Lenka;
Vaiedelich, Enzo;
Gurská, Soňa;
Džubák, Petr;
Hajdúch, Marián;
Hocek, Michal

Publication type:

Article

Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6‐(Thiophen‐2‐yl)‐7‐fluoro‐7‐deazapurine.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 31/32, p. 5409, doi. 10.1002/ejoc.201900509

By:

Malnuit, Vincent;
Smoleń, Sabina;
Tichý, Michal;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 38, p. 12720, doi. 10.1002/chem.201301868

By:

Balintová, Jana;
Plucnara, Medard;
Vidláková, Pavlína;
Pohl, Radek;
Havran, Luděk;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 13, p. 4080, doi. 10.1002/chem.201103270

By:

Raindlová, Veronika;
Pohl, Radek;
Hocek, Michal

Publication type:

Article

Anthraquinone as a Redox Label for DNA: Synthesis, Enzymatic Incorporation, and Electrochemistry of Anthraquinone-Modified Nucleosides, Nucleotides, and DNA.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 50, p. 14063, doi. 10.1002/chem.201101883

By:

Balintová, Jana;
Pohl, Radek;
Horáková, Petra;
Vidláková, Pavlína;
Havran, Luděk;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

Furan-Oxidation-Triggered Inducible DNA Cross-Linking: Acyclic Versus Cyclic Furan-Containing Building Blocks-On the Benefit of Restoring the Cyclic Sugar Backbone.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 25, p. 6940, doi. 10.1002/chem.201100067

By:

Stevens, Kristof;
Claeys, Diederica D.;
Catak, Saron;
Figaroli, Sara;
Hocek, Michal;
Tromp, Jan M.;
Schürch, Stefan;
Van Speybroeck, Veronique;
Madder, Annemieke

Publication type:

Article

Alkylsulfanylphenyl Derivatives of Cytosine and 7-Deazaadenine Nucleosides, Nucleotides and Nucleoside Triphosphates: Synthesis, Polymerase Incorporation to DNA and Electrochemical Study.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 21, p. 5833, doi. 10.1002/chem.201003496

By:

Macíčková-Cahová, Hana;
Pohl, Radek;
Horáková, Petra;
Havran, Luděk;
Špaček, Jan;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article

Theoretical Study of the Stability of the DNA Duplexes Modified by a Series of Hydrophobic Base Analogues.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 31, p. 7601, doi. 10.1002/chem.200802170

By:

Zendlová, Lucie;
Řeha, David;
Hocek, Michal;
Hobza, Pavel

Publication type:

Article

Enzymatic synthesis of reactive RNA probes containing squaramate-linked cytidine or adenosine for bioconjugations and cross-linking with lysine-containing peptides and proteins.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-024-01399-6

By:

Ivancová, Ivana;
Quirante, Tania Sánchez;
Ondruš, Marek;
Pohl, Radek;
Vlková, Marta;
Žilecká, Eva;
Bouřa, Evžen;
Hocek, Michal

Publication type:

Article

Bacteriophage-related epigenetic natural and non-natural pyrimidine nucleotides and their influence on transcription with T7 RNA polymerase.

Published in:

Communications Chemistry, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42004-024-01354-5

By:

Gracias, Filip;
Pohl, Radek;
Sýkorová, Veronika;
Hocek, Michal

Publication type:

Article

Synthesis of Purines Bearing Functionalized C-Substituents by the Conjugate Addition of Nucleophiles to 6-Vinylpurines and 6-Ethynylpurines.

Published in:

European Journal of Organic Chemistry, 2006, v. 2006, n. 22, p. 5083, doi. 10.1002/ejoc.200600545

By:

Martin Kuchař;
Radek Pohl;
Ivan Votruba;
Michal Hocek

Publication type:

Article

A New Modular and Practical Methodology for the Synthesis of 4- or 3-Substituted Phenyl C-Nucleosides.

Published in:

European Journal of Organic Chemistry, 2005, v. 2005, n. 21, p. 4525, doi. 10.1002/ejoc.200500607

By:

Michal Hocek;
Radek Pohl;
Blanka Klepetářová

Publication type:

Article

Highly Methylated Purines and Purinium Salts as Analogues of Heteromines.

Published in:

European Journal of Organic Chemistry, 2005, v. 2005, n. 14, p. 3026, doi. 10.1002/ejoc.200500154

By:

Michal Hocek;
Radek Pohl;
Ivana Císařová

Publication type:

Article

Real‐time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA‐Incorporated Thiazole Orange‐Modified Nucleotides.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 38, p. 1, doi. 10.1002/anie.202307548

By:

Kuba, Miroslav;
Khoroshyy, Petro;
Lepšík, Martin;
Kužmová, Erika;
Kodr, David;
Kraus, Tomáš;
Hocek, Michal

Publication type:

Article

Chloroacetamide‐Modified Nucleotide and RNA for Bioconjugations and Cross‐Linking with RNA‐Binding Proteins.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 7, p. 1, doi. 10.1002/anie.202213764

By:

Brunderová, Mária;
Krömer, Matouš;
Vlková, Marta;
Hocek, Michal

Publication type:

Article

Celebrating Czech Chemistry.

Published in:

ChemPlusChem, 2021, v. 86, n. 1, p. 10, doi. 10.1002/cplu.202000741

By:

Hocek, Michal

Publication type:

Article

2‐Formyl‐dATP as Substrate for Polymerase Synthesis of Reactive DNA Bearing an Aldehyde Group in the Minor Groove.

Published in:

ChemPlusChem, 2020, v. 85, n. 6, p. 1164, doi. 10.1002/cplu.202000287

By:

Krömer, Matouš;
Brunderová, Mária;
Ivancová, Ivana;
Poštová Slavětínská, Lenka;
Hocek, Michal

Publication type:

Article

Methoxyphenol and Dihydrobenzofuran as Oxidizable Labels for Electrochemical Detection of DNA.

Published in:

ChemPlusChem, 2014, v. 79, n. 12, p. 1703, doi. 10.1002/cplu.201402194

By:

Simonova, Anna;
Balintová, Jana;
Pohl, Radek;
Havran, Luděk;
Fojta, Miroslav;
Hocek, Michal

Publication type:

Article