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The Induction Levels of Heat Shock Protein 70 Differentiate the Vulnerabilities to Mutant Huntingtin among Neuronal Subtypes.
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- Journal of Neuroscience, 2007, v. 27, n. 4, p. 868, doi. 10.1523/JNEUROSCI.4522-06.2007
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- Article
In-frame Dystrophin Following Exon 51-Skipping Improves Muscle Pathology and Function in the Exon 52-Deficient mdx Mouse.
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- Molecular Therapy, 2010, v. 18, n. 11, p. 1995, doi. 10.1038/mt.2010.186
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- Article
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
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- Journal of Cell Biology, 2006, v. 172, n. 4, p. 589, doi. 10.1083/jcb.200509132
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- Article
Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
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- EMBO Journal, 2010, v. 29, n. 14, p. 2446, doi. 10.1038/emboj.2010.116
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- Article
Cystathionine β-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS.
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- FASEB Journal, 2005, v. 19, n. 13, p. 1854, doi. 10.1096/fj.05-3724fje
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- Article
A novel form of necrosis, TRIAD, occurs in human Huntington's disease.
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- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0420-1
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- Article
PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35602-w
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- Article
HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice.
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- EMBO Molecular Medicine, 2015, v. 7, n. 1, p. 78, doi. 10.15252/emmm.201404392
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- Article
Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington’s disease.
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- European Journal of Neuroscience, 2008, v. 28, n. 1, p. 30, doi. 10.1111/j.1460-9568.2008.06323.x
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- Article
Mutant huntingtin impairs Ku70-mediated DNA repair.
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- Journal of Cell Biology, 2010, v. 189, n. 3, p. 425, doi. 10.1083/jcb.200905138
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- Article
Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39494-7
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- Article
Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis.
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- Journal of Human Genetics, 2010, v. 55, n. 9, p. 590, doi. 10.1038/jhg.2010.74
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- Article
Mild Maternal Hypothyroxinemia During Pregnancy Induces Persistent DNA Hypermethylation in the Hippocampal Brain-Derived Neurotrophic Factor Gene in Mouse Offspring.
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- Thyroid, 2018, v. 28, n. 3, p. 395, doi. 10.1089/thy.2017.0331
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- Article
Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26851-2
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- Article
Allosteric modulation of the binding affinity between PQBP1 and the spliceosomal protein U5-15kD.
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- FEBS Letters, 2016, v. 590, n. 14, p. 2221, doi. 10.1002/1873-3468.12256
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- Article
Segmental isotope-labeling of the intrinsically disordered protein PQBP1.
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- FEBS Letters, 2014, v. 588, n. 24, p. 4583, doi. 10.1016/j.febslet.2014.10.028
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- Article
Ultra-Early Phase pathologies of Alzheimer's disease and other neurodegenerative diseases.
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- Proceedings of the Japan Academy, Series B Physical & biological sciences, 2017, v. 93, n. 6a, p. 361, doi. 10.2183/pjab.93.022
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- Article
Intracellular amyloid hypothesis for ultra‐early phase pathology of Alzheimer's disease.
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- Neuropathology, 2021, v. 41, n. 2, p. 93, doi. 10.1111/neup.12738
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Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology.
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- Human Molecular Genetics, 2016, v. 25, n. 21, p. 4749, doi. 10.1093/hmg/ddw303
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- Article
RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair.
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- Human Molecular Genetics, 2016, v. 25, n. 20, p. 4432, doi. 10.1093/hmg/ddw272
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Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer’s disease brain.
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- Human Molecular Genetics, 2015, v. 24, n. 2, p. 540, doi. 10.1093/hmg/ddu475
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Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.
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- Human Molecular Genetics, 2014, v. 23, n. 5, p. 1345, doi. 10.1093/hmg/ddt524
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- Article
Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network.
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- Human Molecular Genetics, 2012, v. 21, n. 5, p. 1099, doi. 10.1093/hmg/ddr539
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- Article
Knock-down of PQBP1 impairs anxiety-related cognition in mouse.
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- Human Molecular Genetics, 2009, v. 18, n. 22, p. 4239, doi. 10.1093/hmg/ddp378
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- Article
Targeting Tyro3 ameliorates a model of PGRNmutant FTLD-TDP via tau-mediated synaptic pathology.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02821-z
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- Article
Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01790-z
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- Article
Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15kD.
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- Nature Communications, 2014, v. 5, n. 4, p. 3822, doi. 10.1038/ncomms4822
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- Article
Systematic Analysis of Fly Models with Multiple Drivers Reveals Different Effects of Ataxin-1 and Huntingtin in Neuron Subtype-Specific Expression.
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- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0116567
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- Article
Sox2 Transcriptionally Regulates Pqbp1, an Intellectual Disability-Microcephaly Causative Gene, in Neural Stem Progenitor Cells.
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- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068627
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- Article
Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027408
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- Article
Dynamic Changes of the Phosphoproteome in Postmortem Mouse Brains.
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- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021405
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- Article
Loss of yata, a Novel Gene Regulating the Subcellular Localization of APPL, Induces Deterioration of Neural Tissues and Lifespan Shortening.
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- PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004466
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- Article
Glial Cell Lineage Expression of Mutant Ataxin-1 and Huntingtin Induces Developmental and Late-Onset Neuronal Pathologies in Drosophila Models.
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- PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004262
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Nematode Homologue of PQBP1, a Mental Retardation Causative Gene, Is Involved in Lipid Metabolism.
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- PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004104
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Drosophila PQBP1 Regulates Learning Acquisition at Projection Neurons in Aversive Olfactory Conditioning.
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- Journal of Neuroscience, 2010, v. 30, n. 42, p. 14091, doi. 10.1523/JNEUROSCI.1319-10.2010
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- Article
Role of the Drosophila YATA protein in the proper subcellular localization of COPI revealed by in vivo analysis.
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- Genes & Genetic Systems, 2020, v. 95, n. 6, p. 303, doi. 10.1266/ggs.20-00027
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- Article
PQBP-1 transgenic mice show a late-onset motor neuron disease-like phenotype.
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- Human Molecular Genetics, 2003, v. 12, n. 7, p. 711, doi. 10.1093/hmg/ddg084
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- Article
PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activitation by Brn-2 and affects cell survival.
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- Human Molecular Genetics, 1999, v. 8, n. 6, p. 977, doi. 10.1093/hmg/8.6.977
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- Article
PQBP-1 is expressed predominantly in the central nervous system during development.
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- European Journal of Neuroscience, 2005, v. 22, n. 6, p. 1277, doi. 10.1111/j.1460-9568.2005.04339.x
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- Article
Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex.
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- Journal of Neuroscience, 2019, v. 39, n. 4, p. 678, doi. 10.1523/JNEUROSCI.1634-18.2018
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- Article
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
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- Nature Cell Biology, 2007, v. 9, n. 4, p. 402, doi. 10.1038/ncb1553
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- Article
Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06066-z
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- Article
Suppression of the synaptic localization of a subset of proteins including APP partially ameliorates phenotypes of the Drosophila Alzheimer's disease model.
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- PLoS ONE, 2018, v. 13, n. 9, p. 1, doi. 10.1371/journal.pone.0204048
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- Article
Expression of human PQBP-1 in Drosophila impairs long-term memory and induces abnormal courtship
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- FEBS Letters, 2006, v. 580, n. 9, p. 2335, doi. 10.1016/j.febslet.2006.03.056
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- Article
Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration.
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- Journal of Neurochemistry, 2006, v. 99, n. 1, p. 70, doi. 10.1111/j.1471-4159.2006.04021.x
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- Article
Polyglutamine tract-binding protein-1 dysfunction induces cell death of neurons through mitochondrial stress.
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- Journal of Neurochemistry, 2005, v. 95, n. 3, p. 858, doi. 10.1111/j.1471-4159.2005.03405.x
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- Article
Distinct aggregation and cell death patterns among different types of primary neurons induced by mutant huntingtin protein.
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- Journal of Neurochemistry, 2004, v. 89, n. 4, p. 974, doi. 10.1111/j.1471-4159.2004.02372.x
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- Article
Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein.
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- Journal of Neurochemistry, 2003, v. 87, n. 1, p. 257, doi. 10.1046/j.1471-4159.2003.01991.x
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- Article
Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries.
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- Scientific Reports, 2016, p. 33861, doi. 10.1038/srep33861
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HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease.
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- Scientific Reports, 2016, p. 31895, doi. 10.1038/srep31895
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- Article