Works by Hishinuma, Eiji

Results: 20

Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-01634-7

By:

Kodate, Shun;
Sato, Mitsuharu;
Hishinuma, Eiji;
Kojima, Kaname;
Motoike, Ikuko N.;
Abe, Hikaru;
Abe, Michiaki;
Abe, Momoka;
Abe, Naomi;
Abe, Noriko;
Abe, Tomomi;
Abe, Yuto;
Ahiko, Shizuko;
Aiki, Kayo;
Aizawa, Hiromi;
Akiyama, Yukari;
Anzawa, Hayato;
Aoki, Eri;
Aoki, Yuichi;
Arai, Hiroko

Publication type:

Article

Heterologous expression of high-activity cytochrome P450 in mammalian cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71035-5

By:

Kumondai, Masaki;
Hishinuma, Eiji;
Gutiérrez Rico, Evelyn Marie;
Ito, Akio;
Nakanishi, Yuya;
Saigusa, Daisuke;
Hirasawa, Noriyasu;
Hiratsuka, Masahiro

Publication type:

Article

Functional Characterization of 21 Rare Allelic CYP1A2 Variants Identified in a Population of 4773 Japanese Individuals by Assessing Phenacetin O -Deethylation.

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 8, p. 690, doi. 10.3390/jpm11080690

By:

Kumondai, Masaki;
Gutiérrez Rico, Evelyn Marie;
Hishinuma, Eiji;
Nakanishi, Yuya;
Yamazaki, Shuki;
Ueda, Akiko;
Saito, Sakae;
Tadaka, Shu;
Kinoshita, Kengo;
Saigusa, Daisuke;
Nakayoshi, Tomoki;
Oda, Akifumi;
Hirasawa, Noriyasu;
Hiratsuka, Masahiro

Publication type:

Article

Functional Assessment of 12 Rare Allelic CYP2C9 Variants Identified in a Population of 4773 Japanese Individuals.

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 2, p. 94, doi. 10.3390/jpm11020094

By:

Kumondai, Masaki;
Ito, Akio;
Gutiérrez Rico, Evelyn Marie;
Hishinuma, Eiji;
Ueda, Akiko;
Saito, Sakae;
Nakayoshi, Tomoki;
Oda, Akifumi;
Tadaka, Shu;
Kinoshita, Kengo;
Maekawa, Masamitsu;
Mano, Nariyasu;
Hirasawa, Noriyasu;
Hiratsuka, Masahiro;
Lee, Su-Jun

Publication type:

Article

Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer.

Published in:

Toxins, 2021, v. 13, n. 7, p. 461, doi. 10.3390/toxins13070461

By:

Hishinuma, Eiji;
Shimada, Muneaki;
Matsukawa, Naomi;
Saigusa, Daisuke;
Li, Bin;
Kudo, Kei;
Tsuji, Keita;
Shigeta, Shogo;
Tokunaga, Hideki;
Kumada, Kazuki;
Komine, Keigo;
Shirota, Hidekazu;
Aoki, Yuichi;
Motoike, Ikuko N.;
Yasuda, Jun;
Kinoshita, Kengo;
Yamamoto, Masayuki;
Koshiba, Seizo;
Yaegashi, Nobuo

Publication type:

Article

Importance of Rare DPYD Genetic Polymorphisms for 5-Fluorouracil Therapy in the Japanese Population.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.930470

By:

Hishinuma, Eiji;
Narita, Yoko;
Obuchi, Kai;
Ueda, Akiko;
Saito, Sakae;
Tadaka, Shu;
Kinoshita, Kengo;
Maekawa, Masamitsu;
Mano, Nariyasu;
Hirasawa, Noriyasu;
Hiratsuka, Masahiro

Publication type:

Article

Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2.

Published in:

Molecular & Cellular Biology, 2020, v. 40, n. 22, p. 1, doi. 10.1128/MCB.00377-20

By:

Liam Baird;
Takafumi Suzuki;
Yushi Takahashi;
Eiji Hishinuma;
Daisuke Saigusa;
Masayuki Yamamoto

Publication type:

Article

Identification of predictive biomarkers for diagnosis and radiation sensitivity of uterine cervical cancer using wide‐targeted metabolomics.

Published in:

Journal of Obstetrics & Gynaecology Research, 2023, v. 49, n. 8, p. 2109, doi. 10.1111/jog.15709

By:

Hishinuma, Eiji;
Shimada, Muneaki;
Matsukawa, Naomi;
Li, Bin;
Motoike, Ikuko N.;
Hagihara, Tatsuya;
Shigeta, Shogo;
Tokunaga, Hideki;
Saigusa, Daisuke;
Kinoshita, Kengo;
Koshiba, Seizo;
Yaegashi, Nobuo

Publication type:

Article

Global Proteomics for Identifying the Alteration Pathway of Niemann–Pick Disease Type C Using Hepatic Cell Models.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 21, p. 15642, doi. 10.3390/ijms242115642

By:

Miyoshi, Keitaro;
Hishinuma, Eiji;
Matsukawa, Naomi;
Shirasago, Yoshitaka;
Watanabe, Masahiro;
Sato, Toshihiro;
Sato, Yu;
Kumondai, Masaki;
Kikuchi, Masafumi;
Koshiba, Seizo;
Fukasawa, Masayoshi;
Maekawa, Masamitsu;
Mano, Nariyasu

Publication type:

Article

Comparative Evaluation of Plasma Metabolomic Data from Multiple Laboratories.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/metabo12020135

By:

Nishiumi, Shin;
Izumi, Yoshihiro;
Hirayama, Akiyoshi;
Takahashi, Masatomo;
Nakao, Motonao;
Hata, Kosuke;
Saigusa, Daisuke;
Hishinuma, Eiji;
Matsukawa, Naomi;
Tokuoka, Suzumi M.;
Kita, Yoshihiro;
Hamano, Fumie;
Okahashi, Nobuyuki;
Ikeda, Kazutaka;
Nakanishi, Hiroki;
Saito, Kosuke;
Hirai, Masami Yokota;
Yoshida, Masaru;
Oda, Yoshiya;
Matsuda, Fumio

Publication type:

Article

Comparison of Kit-Based Metabolomics with Other Methodologies in a Large Cohort, towards Establishing Reference Values.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 10, p. 652, doi. 10.3390/metabo11100652

By:

Saigusa, Daisuke;
Hishinuma, Eiji;
Matsukawa, Naomi;
Takahashi, Masatomo;
Inoue, Jin;
Tadaka, Shu;
Motoike, Ikuko N.;
Hozawa, Atsushi;
Izumi, Yoshihiro;
Bamba, Takeshi;
Kinoshita, Kengo;
Ekroos, Kim;
Koshiba, Seizo;
Yamamoto, Masayuki

Publication type:

Article

jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population.

Published in:

Nucleic Acids Research, 2021, v. 49, n. D1, p. D536, doi. 10.1093/nar/gkaa1034

By:

Tadaka, Shu;
Hishinuma, Eiji;
Komaki, Shohei;
Motoike, Ikuko N;
Kawashima, Junko;
Saigusa, Daisuke;
Inoue, Jin;
Takayama, Jun;
Okamura, Yasunobu;
Aoki, Yuichi;
Shirota, Matsuyuki;
Otsuki, Akihito;
Katsuoka, Fumiki;
Shimizu, Atsushi;
Tamiya, Gen;
Koshiba, Seizo;
Sasaki, Makoto;
Yamamoto, Masayuki;
Kinoshita, Kengo

Publication type:

Article

Rapid Genetic Diagnosis for Okinawan Patients with Enlarged Vestibular Aqueduct Using Single-Stranded Tag Hybridization Chromatographic Printed-Array Strip.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 4, p. N.PAG, doi. 10.3390/jcm11041099

By:

Ganaha, Akira;
Hishinuma, Eiji;
Kaname, Tadashi;
Hiratsuka, Masahiro;
Kondo, Shunsuke;
Tono, Tetsuya

Publication type:

Article

In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 8, p. 2342, doi. 10.3390/jcm9082342

By:

Hishinuma, Eiji;
Gutiérrez Rico, Evelyn;
Hiratsuka, Masahiro

Publication type:

Article

Genetic Polymorphisms of Dihydropyrimidinase in a Japanese Patient with Capecitabine-Induced Toxicity.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0124818

By:

Hiratsuka, Masahiro;
Yamashita, Hiroshi;
Akai, Fumika;
Hosono, Hiroki;
Hishinuma, Eiji;
Hirasawa, Noriyasu;
Mori, Takahiro

Publication type:

Article

Dietary habits and plasma lipid concentrations in a general Japanese population.

Published in:

Metabolomics, 2024, v. 20, n. 2, p. 1, doi. 10.1007/s11306-024-02087-1

By:

Sato, Mitsuharu;
Hishinuma, Eiji;
Matsukawa, Naomi;
Shima, Yoshiko;
Saigusa, Daisuke;
Motoike, Ikuko N.;
Kogure, Mana;
Nakaya, Naoki;
Hozawa, Atsushi;
Kuriyama, Shinichi;
Yamamoto, Masayuki;
Koshiba, Seizo;
Kinoshita, Kengo

Publication type:

Article

Identification of predictive biomarkers for endometrial cancer diagnosis and treatment response monitoring using plasma metabolome profiling.

Published in:

Cancer & Metabolism, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40170-023-00317-z

By:

Hishinuma, Eiji;
Shimada, Muneaki;
Matsukawa, Naomi;
Shima, Yoshiko;
Li, Bin;
Motoike, Ikuko N.;
Shibuya, Yusuke;
Hagihara, Tatsuya;
Shigeta, Shogo;
Tokunaga, Hideki;
Saigusa, Daisuke;
Kinoshita, Kengo;
Koshiba, Seizo;
Yaegashi, Nobuo

Publication type:

Article

jMorp: Japanese Multi-Omics Reference Panel update report 2023.

Published in:

Nucleic Acids Research, 2024, v. 52, n. D1, p. D622, doi. 10.1093/nar/gkad978

By:

Tadaka, Shu;
Kawashima, Junko;
Hishinuma, Eiji;
Saito, Sakae;
Okamura, Yasunobu;
Otsuki, Akihito;
Kojima, Kaname;
Komaki, Shohei;
Aoki, Yuichi;
Kanno, Takanari;
Saigusa, Daisuke;
Inoue, Jin;
Shirota, Matsuyuki;
Takayama, Jun;
Katsuoka, Fumiki;
Shimizu, Atsushi;
Tamiya, Gen;
Shimizu, Ritsuko;
Hiratsuka, Masahiro;
Motoike, Ikuko N

Publication type:

Article

Nrf2 plays a critical role in the metabolic response during and after spaceflight.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02904-6

By:

Uruno, Akira;
Saigusa, Daisuke;
Suzuki, Takafumi;
Yumoto, Akane;
Nakamura, Tomohiro;
Matsukawa, Naomi;
Yamazaki, Takahiro;
Saito, Ristumi;
Taguchi, Keiko;
Suzuki, Mikiko;
Suzuki, Norio;
Otsuki, Akihito;
Katsuoka, Fumiki;
Hishinuma, Eiji;
Okada, Risa;
Koshiba, Seizo;
Tomioka, Yoshihisa;
Shimizu, Ritsuko;
Shirakawa, Masaki;
Kensler, Thomas W.

Publication type:

Article

Identifying critical age and gender-based metabolomic shifts in a Japanese population of the Tohoku Medical Megabank cohort.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-66180-0

By:

Sakurai, Miyuki;
Motoike, Ikuko N.;
Hishinuma, Eiji;
Aoki, Yuichi;
Tadaka, Shu;
Kogure, Mana;
Orui, Masatsugu;
Ishikuro, Mami;
Obara, Taku;
Nakaya, Naoki;
Kumada, Kazuki;
Hozawa, Atsushi;
Kuriyama, Shinichi;
Yamamoto, Masayuki;
Koshiba, Seizo;
Kinoshita, Kengo

Publication type:

Article