Works by Hirte, Hal

Results: 25

Immunology: CD56 lymphoid cells in human first trimester pregnancy decidua as a source of novel transforming growth factor-β2-related immunosuppressive factors.

Published in:

Human Reproduction, 1994, v. 9, n. 12, p. 2270

By:

Clark, David A.;
Vince, Gill;
Flanders, Kathleen C.;
Hirte, Hal;
Starkey, Phyllis

Publication type:

Article

A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575)

Published in:

2014

By:

Richter, Suzanne;
Bedard, Philippe;
Chen, Eric;
Clarke, Blaise;
Tran, Ben;
Hotte, Sebastien;
Stathis, Anastasios;
Hirte, Hal;
Razak, Albiruni;
Reedijk, Michael;
Chen, Zhuo;
Cohen, Brenda;
Zhang, Wen-Jiang;
Wang, Lisa;
Ivy, S.;
Moore, Malcolm;
Oza, Amit;
Siu, Lillian;
McWhirter, Elaine

Publication type:

Journal Article

A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575).

Published in:

Investigational New Drugs, 2014, v. 32, n. 2, p. 243, doi. 10.1007/s10637-013-9965-4

By:

Richter, Suzanne;
Bedard, Philippe;
Chen, Eric;
Clarke, Blaise;
Tran, Ben;
Hotte, Sebastien;
Stathis, Anastasios;
Hirte, Hal;
Razak, Albiruni;
Reedijk, Michael;
Chen, Zhuo;
Cohen, Brenda;
Zhang, Wen-Jiang;
Wang, Lisa;
Ivy, S.;
Moore, Malcolm;
Oza, Amit;
Siu, Lillian;
McWhirter, Elaine

Publication type:

Article

A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2013, v. 31, n. 5, p. 1182, doi. 10.1007/s10637-013-0001-5

By:

Diaz-Padilla, Ivan;
Hirte, Hal;
Oza, Amit;
Clarke, Blaise;
Cohen, Brenda;
Reedjik, Michael;
Zhang, Tong;
Kamel-Reid, Suzanne;
Ivy, S.;
Hotte, Sebastien;
Razak, Albiruni;
Chen, Eric;
Brana, Irene;
Wizemann, Monika;
Wang, Lisa;
Siu, Lillian;
Bedard, Philippe

Publication type:

Article

Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Sorafenib: A Review of Four Phase I Trials in Patients with Advanced Refractory Solid Tumors.

Published in:

Oncologist, 2007, v. 12, n. 4, p. 426, doi. 10.1634/theoncologist.12-4-426

By:

Strumberg, Dirk;
Clark, Jeffrey W.;
Awada, Ahmad;
Moore, Malcolm J.;
Richly, Heike;
Hendlisz, Alain;
Hirte, Hal W.;
Eder, Joseph P.;
Lenz, Heinz-Josef;
Schwartz, Brian

Publication type:

Article

Marizomib for patients with newly diagnosed glioblastoma: A randomized phase 3 trial.

Published in:

Neuro-Oncology, 2024, v. 26, n. 9, p. 1670, doi. 10.1093/neuonc/noae053

By:

Roth, Patrick;
Gorlia, Thierry;
Reijneveld, Jaap C;
Vos, Filip de;
Idbaih, Ahmed;
Frenel, Jean-Sébastien;
Rhun, Emilie Le;
Sepulveda, Juan Manuel;
Perry, James;
Masucci, G Laura;
Freres, Pierre;
Hirte, Hal;
Seidel, Clemens;
Walenkamp, Annemiek;
Lukacova, Slavka;
Meijnders, Paul;
Blais, Andre;
Ducray, Francois;
Verschaeve, Vincent;
Nicholas, Garth

Publication type:

Article

Neoadjuvant and Adjuvant Systemic Therapy for Newly Diagnosed Stage II–IV Epithelial Ovary, Fallopian Tube, or Primary Peritoneal Carcinoma: A Practice Guideline.

Published in:

Current Oncology, 2022, v. 29, n. 1, p. 231, doi. 10.3390/curroncol29010022

By:

Hirte, Hal;
Poon, Raymond;
Yao, Xiaomei;
May, Taymaa;
Ethier, Josee-Lyne;
Petz, Lauri;
Speakman, Jane;
Elit, Laurie

Publication type:

Article

An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline: Consolidation or Maintenance Systemic Therapy for Newly Diagnosed Stage II, III, or IV Epithelial Ovary, Fallopian Tube, or Primary Peritoneal Carcinoma.

Published in:

Current Oncology, 2021, v. 28, n. 2, p. 1114, doi. 10.3390/curroncol28020107

By:

Hirte, Hal;
Xiaomei Yao;
Ferguson, Sarah E.;
May, Taymaa;
Elit, Laurie

Publication type:

Article

Establishment and characterization of four human epithelial ovarian carcinoma cell lines.

Published in:

1994

By:

Hirte, Hal W.;
Kaiser, Jutta S.;
Bacchetti, Silvia;
Hirte, H W;
Kaiser, J S;
Bacchetti, S

Publication type:

journal article

Phase I clinical trial of recombinant human interleukin-3 combined with carboplatin in the treatment of patients with recurrent ovarian carcinoma.

Published in:

1993

By:

Rusthoven, James J.;
Eisenhauer, Elizabeth;
Mazurka, John;
Hirte, Hal;
O'Connell, Greg;
Muldal, Alison;
Lu, Hai-xiao;
Onetto, Nicole;
Swenerton, Kenneth;
Jeffrey, John;
Rusthoven, J J;
Eisenhauer, E;
Mazurka, J;
Hirte, H;
O'Connell, G;
Muldal, A;
Lu, H X;
Onetto, N;
Swenerton, K;
Jeffrey, J

Publication type:

journal article

Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 4, p. 575, doi. 10.1007/s00262-017-2112-x

By:

Nham, Tina;
Poznanski, Sophie M.;
Fan, Isabella Y.;
Shenouda, Mira M.;
Chew, Marianne V.;
Lee, Amanda J.;
Vahedi, Fatemeh;
Karimi, Yalda;
Butcher, Martin;
Lee, Dean A.;
Hirte, Hal;
Ashkar, Ali A.

Publication type:

Article

Testing personalized medicine: patient and physician expectations of next-generation genomic sequencing in late-stage cancer care.

Published in:

European Journal of Human Genetics, 2014, v. 22, n. 3, p. 391, doi. 10.1038/ejhg.2013.158

By:

Miller, Fiona A;
Hayeems, Robin Z;
Bytautas, Jessica P;
Bedard, Philippe L;
Ernst, Scott;
Hirte, Hal;
Hotte, Sebastien;
Oza, Amit;
Razak, Albiruni;
Welch, Stephen;
Winquist, Eric;
Dancey, Janet;
Siu, Lillian L

Publication type:

Article

Management of advanced or recurrent cervical cancer: chemotherapy and beyond.

Published in:

Expert Review of Anticancer Therapy, 2014, v. 14, n. 3, p. 319, doi. 10.1586/14737140.2014.866041

By:

Elit, Laurie M;
Hirte, Hal

Publication type:

Article

Feasibility of real time next generation sequencing of cancer genes linked to drug response: Results from a clinical trial.

Published in:

International Journal of Cancer, 2013, v. 132, n. 7, p. 1547, doi. 10.1002/ijc.27817

By:

Tran, Ben;
Brown, Andrew M.K.;
Bedard, Philippe L.;
Winquist, Eric;
Goss, Glenwood D.;
Hotte, Sebastien J.;
Welch, Stephen A.;
Hirte, Hal W.;
Zhang, Tong;
Stein, Lincoln D.;
Ferretti, Vincent;
Watt, Stuart;
Jiao, Wei;
Ng, Karen;
Ghai, Sangeet;
Shaw, Patricia;
Petrocelli, Teresa;
Hudson, Thomas J.;
Neel, Benjamin G.;
Onetto, Nicole

Publication type:

Article

Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma.

Published in:

OncoTargets & Therapy, 2013, v. 6, p. 427, doi. 10.2147/OTT.S30373

By:

Hirte, Hal W.

Publication type:

Article

Palliative systemic therapy for women with recurrent epithelial ovarian cancer: current options.

Published in:

OncoTargets & Therapy, 2013, v. 6, p. 107, doi. 10.2147/OTT.S30238

By:

Elit, Laurie;
Hirte, Hal

Publication type:

Article

Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C.

Published in:

Cells (2073-4409), 2020, v. 9, n. 11, p. 2408, doi. 10.3390/cells9112408

By:

Kolendowski, Bart;
Valdes, Yudith Ramos;
Hirte, Hal;
Itamochi, Hiroaki;
Lee, Wonjae;
Carey, Mark;
Shepherd, Trevor G.;
DiMattia, Gabriel E.

Publication type:

Article

Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors.

Published in:

Investigational New Drugs, 2021, v. 39, n. 6, p. 1587, doi. 10.1007/s10637-021-01141-2

By:

Italiano, Antoine;
Miller Jr, Wilson H.;
Blay, Jean-Yves;
Gietema, Jourik A.;
Bang, Yung-Jue;
Mileshkin, Linda R.;
Hirte, Hal W.;
Higgins, Brian;
Blotner, Steven;
Nichols, Gwen L.;
Chen, Lin Chi;
Petry, Claire;
Yang, Qi Joy;
Schmitt, Christophe;
Jamois, Candice;
Siu, Lillian L.

Publication type:

Article

A phase I trial of ANG1/2-Tie2 inhibitor trebaninib (AMG386) and temsirolimus in advanced solid tumors (PJC008/NCI♯9041).

Published in:

Investigational New Drugs, 2016, v. 34, n. 1, p. 104, doi. 10.1007/s10637-015-0313-8

By:

Chiu, Joanne;
Hotte, Sebastien;
Kollmannsberger, Christian;
Renouf, Daniel;
Cescon, David;
Hedley, David;
Chow, Sue;
Moscow, Jeffrey;
Chen, Zhuo;
Perry, Meghan;
Diaz-Padilla, Ivan;
Tan, David;
Hirte, Hal;
McWhirter, Elaine;
Chen, Helen;
Siu, Lillian;
Bedard, Philippe

Publication type:

Article

A phase I, dose-escalation trial of continuous- and pulsed-dose afatinib combined with pemetrexed in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2014, v. 32, n. 6, p. 1226, doi. 10.1007/s10637-014-0139-9

By:

Chu, Quincy;
Sangha, Randeep;
Hotte, Sebastien;
Sergenson, Gwen;
Schnell, David;
Chand, Vikram;
Hirte, Hal

Publication type:

Article

Two Phase I Studies of Carboplatin Dose Escalation in Chemotherapy-Naive Ovarian Cancer Patients Supported With Patients Supported With Granulocyte-Macrophage Colony-Stimulating Factor.

Published in:

JNCI: Journal of the National Cancer Institute, 1991, v. 83, n. 23, p. 1748, doi. 10.1093/jnci/83.23.1748

By:

Rusthoven, James;
Levin, Les;
Eisenhauer, Elizabeth;
Mazurka, John;
Carmichael, John;
O'Connell, Gregory;
Bryson, Peter;
Hirte, Hal;
Koski, Beverly

Publication type:

Article

Evaluation of DNA Methylation Array for Glioma Tumor Profiling and Description of a Novel Epi-Signature to Distinguish IDH1/IDH2 Mutant and Wild-Type Tumors.

Published in:

Genes, 2022, v. 13, n. 11, p. 2075, doi. 10.3390/genes13112075

By:

Schenkel, Laila C.;
Mathew, Joseph;
Hirte, Hal;
Provias, John;
Paré, Guillaume;
Chong, Michael;
Grafodatskaya, Daria;
McCready, Elizabeth

Publication type:

Article

Phase I Study of BI 853520, an Inhibitor of Focal Adhesion Kinase, in Patients with Advanced or Metastatic Nonhematologic Malignancies.

Published in:

2019

By:

de Jonge, Maja J. A.;
Steeghs, Neeltje;
Lolkema, Martijn P.;
Hotte, Sebastien J.;
Hirte, Hal W.;
van der Biessen, Diane A. J.;
Abdul Razak, Albiruni R.;
De Vos, Filip Y. F. L.;
Verheijen, Remy B.;
Schnell, David;
Pronk, Linda C.;
Jansen, Monique;
Siu, Lillian L.

Publication type:

journal article

Randomized, Open-Label, Crossover Studies Evaluating the Effect of Food and Liquid Formulation on the Pharmacokinetics of the Novel Focal Adhesion Kinase (FAK) Inhibitor BI 853520.

Published in:

2019

By:

Verheijen, Remy B.;
van der Biessen, Diane A. J.;
Hotte, Sebastien J.;
Siu, Lillian L.;
Spreafico, Anna;
de Jonge, Maja J. A.;
Pronk, Linda C.;
De Vos, Filip Y. F. L.;
Schnell, David;
Hirte, Hal W.;
Steeghs, Neeltje;
Lolkema, Martijn P.

Publication type:

journal article

A Phase II Multicentre, Open-Label, Proof-of-Concept Study of Tasquinimod in Hepatocellular, Ovarian, Renal Cell, and Gastric Cancers.

Published in:

2017

By:

Escudier, Bernard;
Faivre, Sandrine;
Cutsem, Eric;
Germann, Nathalie;
Pouget, Jean-Christophe;
Plummer, Ruth;
Vergote, Ignace;
Thistlethwaite, Fiona;
Bjarnason, Georg;
Jones, Robert;
Mackay, Helen;
Edeline, Julien;
Fartoux, Laetitia;
Hirte, Hal;
Oza, Amit;
Van Cutsem, Eric;
Bjarnason, Georg A

Publication type:

journal article