Works by Hirshman, Michael F.

Results: 67

Exercise training-induced adaptations associated with increases in skeletal muscle glycogen content.

Published in:

FEBS Journal, 2013, v. 280, n. 3, p. 916, doi. 10.1111/febs.12085

By:

Manabe, Yasuko;
Gollisch, Katja S. C.;
Holton, Laura;
Kim, Young ‐ Bum;
Brandauer, Josef;
Fujii, Nobuharu L.;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis.

Published in:

2016

By:

O'Neill, Brian T.;
Lee, Kevin Y.;
Klaus, Katherine;
Softic, Samir;
Krumpoch, Megan T.;
Fentz, Joachim;
Stanford, Kristin I.;
Robinson, Matthew M.;
Weikang Cai;
Kleinridders, Andre;
Pereira, Renata O.;
Hirshman, Michael F.;
Abel, E. Dale;
Accili, Domenico;
Goodyear, Laurie J.;
Nair, K. Sreekumaran;
Kahn, C. Ronald;
Cai, Weikang

Publication type:

journal article

The AMPK-related kinase SNARK regulates muscle mass and myocyte survival.

Published in:

2016

By:

Lessard, Sarah J.;
Rivas, Donato A.;
Kawai So;
Ho-Jin Koh;
Queiroz, André Lima;
Hirshman, Michael F.;
Fielding, Roger A.;
Goodyear, Laurie J.;
So, Kawai;
Koh, Ho-Jin

Publication type:

journal article

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 1, p. 215, doi. 10.1172/JCI62308

By:

Stanford, Kristin I.;
Middelbeek, Roeland J. W.;
Townsend, Kristy L.;
Ding An;
Nygaard, Eva B.;
Hitchcox, Kristen M.;
Markan, Kathleen R.;
Nakano, Kazuhlro;
Hirshman, Michael F.;
Tseng, Yu-Hua;
Goodyear, Laurie J.

Publication type:

Article

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.

Published in:

2007

By:

Luptak, Ivan;
Mei Shen;
Huamei He;
Hirshman, Michael F.;
Musi, Nicolas;
Goodyear, Laurie J.;
Jie Yan;
Wakimoto, Hiroko;
Morita, Hiroyuki;
Arad, Michael;
Seidman, Christine E.;
Seidman, J. G.;
Ingwall, Joanne S.;
Balschi, James A.;
Rong Tian;
Shen, Mei;
He, Huamei;
Yan, Jie;
Tian, Rong

Publication type:

journal article

Functional role of AMP-activated protein kinase in the heart during exercise

Published in:

FEBS Letters, 2005, v. 579, n. 10, p. 2045, doi. 10.1016/j.febslet.2005.02.052

By:

Musi, Nicolas;
Hirshman, Michael F.;
Arad, Michael;
Xing, Yanqiu;
Fujii, Nobuharu;
Pomerleau, Jason;
Ahmad, Ferhaan;
Berul, Charles I.;
Seidman, Jon G.;
Tian, Rong;
Goodyear, Laurie J.

Publication type:

Article

Regulation of glucose transport by the AMP-activated protein kinase.

Published in:

Proceedings of the Nutrition Society, 2004, v. 63, n. 2, p. 205, doi. 10.1079/PNS2004340

By:

Fujii, Nobuharu;
Aschenbach, William G.;
Musi, Nicolas;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

Published in:

Nature Medicine, 2000, v. 6, n. 8, p. 924, doi. 10.1038/78693

By:

Zisman, Ariel;
Peroni, Odile D.;
Abel, E. Dale;
Michael, M. Dodson;
Mauvais-Jarvis, Franck;
Lowell, Bradford B.;
Wojtaszewski, Jorgen F.P.;
Hirshman, Michael F.;
Virkamaki, Antti;
Goodyear, Laurie J.;
Kahn, C. Ronald;
Kahn, Barbara B.

Publication type:

Article

Skeletal Muscle-Selective Knockout of LKB1 Increases Insulin Sensitivity, Improves Glucose Homeostasis, and Decreases TRB3.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 22, p. 1, doi. 10.1128/MCB.00979-06

By:

Ho-Jin Koh;
Arnolds, David E.;
Fujii, Nobuharu;
Tran, Thien T.;
Rogers, Marc J.;
Jessen, Niels;
Yangfeng Li;
Chng Wee Liew;
Ho, Richard C.;
Hirshman, Michael F.;
Kulkarni, Rohit N.;
Kahn, C. Ronald;
Goodyear, Laurie J.

Publication type:

Article

Sucrose nonfermenting AMPK‐related kinase (SNARK) regulates exercise‐stimulated and ischemia‐stimulated glucose transport in the heart.

Published in:

Journal of Cellular Biochemistry, 2019, v. 120, n. 1, p. 685, doi. 10.1002/jcb.27425

By:

Sun, Xiang‐Lan;
Lessard, Sarah J.;
An, Ding;
Koh, Ho‐Jin;
Esumi, Hiroyasu;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.

Published in:

Nature Communications, 2015, v. 6, n. 8, p. 8054, doi. 10.1038/ncomms9054

By:

Lee, Kevin Y.;
Singh, Manvendra K.;
Ussar, Siegfried;
Wetzel, Petra;
Hirshman, Michael F.;
Goodyear, Laurie J.;
Kispert, Andreas;
Kahn, C. Ronald

Publication type:

Article

Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle.

Published in:

Nature Communications, 2013, v. 4, n. 5, p. 1871, doi. 10.1038/ncomms2851

By:

Koh, Ho-Jin;
Toyoda, Taro;
Didesch, Michelle M.;
Lee, Min-Young;
Sleeman, Mark W.;
Kulkarni, Rohit N.;
Musi, Nicolas;
Hirshman, Michael F;
Goodyear, Laurie J.

Publication type:

Article

JNK regulates muscle remodeling via myostatin/SMAD inhibition.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05439-3

By:

Lessard, Sarah J.;
MacDonald, Tara L.;
Pathak, Prerana;
Han, Myoung Sook;
Coffey, Vernon G.;
Edge, Johann;
Rivas, Donato A.;
Hirshman, Michael F.;
Davis, Roger J.;
Goodyear, Laurie J.

Publication type:

Article

The Role of Skeletal Muscle Tribbles 3 (TRB3) on Endoplasmic Reticulum (ER) stress‐ and high fat diet‐induced insulin resistance.

Published in:

FASEB Journal, 2013, v. 27, p. 1154.5, doi. 10.1096/fasebj.27.1_supplement.1154.5

By:

Koh, Ho‐Jin;
Toyoda, Taro;
Jung, Michelle M;
Lee, Min‐Young;
Hirshman, Michael F;
Goodyear, Laurie J

Publication type:

Article

Maternal Exercise During Pregnancy Improves Glucose Metabolism of Offspring.

Published in:

FASEB Journal, 2013, v. 27, p. 1134.4, doi. 10.1096/fasebj.27.1_supplement.1134.4

By:

Stanford, Kristin I.;
Lee, Min‐Young;
Getchell, Kristen M.;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

LKB1 regulates contraction-stimulated glucose transport in mouse skeletal muscle.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1208

By:

Ho-Jin Koh;
Hirshman, Michael F.;
Peter, Lauren E.;
Yangfeng Li;
Fujii, Nobuharu;
Goodyear, Laurie J.

Publication type:

Article

Fiber type-specific regulation of the Akt substrate of 160 kDa (AS160) in mouse skeletal muscle.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1207, doi. 10.1096/fasebj.21.6.a1207-b

By:

Taylor, Eric B.;
Kramer, Henning F.;
Fujii, Nobuharu L.;
Haiyan Yu;
Roeckl, Katja S. C.;
Witczak, Carol A.;
Sano, Hiroyuki;
Peter, Lauren E.;
Hirshman, Michael F.;
Lienhard, Gustav E.;
Goodyear, Laurie J.

Publication type:

Article

CaMKKα regulates glucose uptake independent of AMPK and Akt signaling in mouse skeletal muscle.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A836, doi. 10.1096/fasebj.21.6.a836

By:

Witczak, Carol A.;
Fujii, Nobuharu;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Maternal Exercise Improves Glucose Tolerance in Female Offspring.

Published in:

Diabetes, 2017, v. 66, n. 8, p. 2124, doi. 10.2337/db17-0098

By:

Stanford, Kristin I.;
Hirokazu Takahashi;
Kawai So;
Alves-Wagner, Ana Barbara;
Prince, Noah B.;
Lehnig, Adam C.;
Getchell, Kristen M.;
Min-Young Lee;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Maternal Exercise Improves Glucose Tolerance in Female Offspring.

Published in:

2017

By:

Stanford, Kristin I;
Takahashi, Hirokazu;
So, Kawai;
Alves-Wagner, Ana Barbara;
Prince, Noah B;
Lehnig, Adam C;
Getchell, Kristen M;
Lee, Min-Young;
Hirshman, Michael F;
Goodyear, Laurie J

Publication type:

journal article

A Novel Role for Subcutaneous Adipose Tissue in Exercise-Induced Improvements in Glucose Homeostasis.

Published in:

Diabetes, 2015, v. 64, n. 6, p. 2002, doi. 10.2337/db14-0704

By:

Stanford, Kristin I.;
Middelbeek, Roeland J. W.;
Townsend, Kristy L.;
Min-Young Lee;
Hirokazu Takahashi;
Kawai So;
Hitchcox, Kristen M.;
Markan, Kathleen R.;
Hellbach, Katharina;
Hirshman, Michael F.;
Yu-Hua Tseng;
Goodyear, Laurie J.

Publication type:

Article

Exercise Before and During Pregnancy Prevents the Deleterious Effects of Maternal High-Fat Feeding on Metabolic Health of Male Offspring.

Published in:

Diabetes, 2015, v. 64, n. 2, p. 427, doi. 10.2337/db13-1848

By:

Stanford, Kristin I.;
Min-Young Lee;
Getchell, Kristen M.;
Kawai So;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Contraction and AICAR Stimulate IL-6 Vesicle Depletion From Skeletal Muscle Fibers In Vivo.

Published in:

Diabetes, 2013, v. 62, n. 9, p. 3081, doi. 10.2337/db12-1261

By:

Lauritzen, Hans P. M. M.;
Brandauer, Josef;
Schjerling, Peter;
Ho-Jin Koh;
Treebak, Jonas T.;
Hirshman, Michael F.;
Galbo, Henrik;
Goodyear, Laurie J.

Publication type:

Article

Resistance to Aerobic Exercise Training Causes Metabolic Dysfunction and Reveals Novel Exercise-Regulated Signaling Networks.

Published in:

Diabetes, 2013, v. 62, n. 8, p. 2717, doi. 10.2337/db13-0062

By:

Lessard, Sarah J.;
Rivas, Donato A.;
Alves-Wagner, Ana B.;
Hirshman, Michael F.;
Gallagher, Iain J.;
Constantin-Teodosiu, Dumitru;
Atkins, Ryan;
Greenhaff, Paul L.;
Qi, Nathan R.;
Gustafsson, Thomas;
Fielding, Roger A.;
Timmons, James A.;
Britton, Steven L.;
Koch, Lauren G.;
Goodyear, Laurie J.

Publication type:

Article

TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.

Published in:

2010

By:

An D;
Toyoda T;
Taylor EB;
Yu H;
Fujii N;
Hirshman MF;
Goodyear LJ;
An, Ding;
Toyoda, Taro;
Taylor, Eric B;
Yu, Haiyan;
Fujii, Nobuharu;
Hirshman, Michael F;
Goodyear, Laurie J

Publication type:

journal article

TBCID1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle.

Published in:

Diabetes, 2010, v. 59, n. 6, p. 1358, doi. 10.2337/db09-1266

By:

An, Ding;
Toyoda, Taro;
Taylor, Eric B.;
Yu, Haiyan;
Fujii, Nobuharu;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice.

Published in:

2008

By:

Fujii N;
Ho RC;
Manabe Y;
Jessen N;
Toyoda T;
Holland WL;
Summers SA;
Hirshman MF;
Goodyear LJ;
Fujii, Nobuharu;
Ho, Richard C;
Manabe, Yasuko;
Jessen, Niels;
Toyoda, Taro;
Holland, William L;
Summers, Scott A;
Hirshman, Michael F;
Goodyear, Laurie J

Publication type:

journal article

Ablation of AMP-Activated Protein Kinase α2 Activity Exacerbates Insulin Resistance Induced by High-Fat Feeding of Mice.

Published in:

Diabetes, 2008, v. 57, n. 11, p. 2958, doi. 10.2337/db07-1187

By:

Fujii, Nobuharu;
Ho, Richard C.;
Manabe, Yasuko;
Jessen, Niels;
Toyoda, Taro;
Holland, William L.;
Summers, Scott A.;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Calmodulin-Binding Domain of AS160 Regulates Contraction- but Not Insulin-Stimulated Glucose Uptake in Skeletal Muscle.

Published in:

Diabetes, 2007, v. 56, n. 12, p. 2854, doi. 10.2337/db07-0681

By:

Kramer, Henning F.;
Taylor, Eric B.;
Witczak, Carol A.;
Fujii, Nobuharu;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift.

Published in:

2007

By:

Röckl KSC;
Hirshman MF;
Brandauer J;
Fujii N;
Witters LA;
Goodyear LJ;
Röckl, Katja S C;
Hirshman, Michael F;
Brandauer, Josef;
Fujii, Nobuharu;
Witters, Lee A;
Goodyear, Laurie J

Publication type:

journal article

Skeletal Muscle Adaptation to Exercise Training.

Published in:

Diabetes, 2007, v. 56, n. 8, p. 2062, doi. 10.2337/db07-0255

By:

Röckl, Katja S. C.;
Hirshman, Michael F.;
Brandauer, Josef;
Fujii, Nobuharu;
Witters, Lee A.;
Goodyear, Laurie J.

Publication type:

Article

Combined Effects of Metformin and Exercise on AMPK α2 Activity and Insulin Action in Insulin Resistant Individuals.

Published in:

Diabetes, 2007, v. 56, p. A283

By:

Sharoff, Carrie G.;
Hagobian, Todd A.;
Chipkin, Stuart R.;
Yu, Haiyan;
Hirshman, Michael F.;
Goodyear, Laurie J.;
Braun, Barry

Publication type:

Article

Skeletal Muscle Adaptation to Exercise Training: AMP-Activated Protein Kinase Mediates Muscle Fiber Type Shift.

Published in:

Diabetes, 2007, v. 56, p. A37

By:

Roeckl, Katja S.;
Hirshman, Michael F.;
Brandauer, Josef;
Fujii, Nobuharu;
Witters, Lee A.;
Goodyear, Laurie J.

Publication type:

Article

The Calmodulin-Binding Domain of the Akt Substrate of 160 KDa (AS160) Regulates Contraction- but not Insulin-Stimulated Glucose Uptake.

Published in:

Diabetes, 2007, v. 56, p. A37

By:

Kramer, Henning F.;
Witczak, Carol A.;
Taylor, Eric B.;
Fujii, Nobuharu;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase Kinase-α Regulates Skeletal Muscle Glucose Uptake Independent of AMP-Activated Protein Kinase and Akt Activation.

Published in:

Diabetes, 2007, v. 56, n. 5, p. 1403, doi. 10.2337/db06-1230

By:

Witczak, Carol A.;
Fujii, Nobuharu;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Article

Distinct Signals Regulate AS160 Phosphorylation in Response to Insulin, AICAR, and Contraction in Mouse Skeletal Muscle.

Published in:

2006

By:

Kramer, Henning F.;
Witczak, Carol A.;
Fujii, Nobuharu;
Jessen, Niels;
Taylor, Eric B.;
Arnolds, David E.;
Sakamoto, Kei;
Hirshman, Michael F.;
Goodyear, Laurie J.

Publication type:

Abstract

Insulin resistance and lipodystrophy in mice lacking ribosomal S6 kinase 2.

Published in:

2003

By:

El-Haschimi, Karim;
Dufresne, Scott D.;
Hirshman, Michael F.;
Flier, Jeffrey S.;
Goodyear, Laurie J.;
Bjørbæk, Christian;
Bjørbaek, Christian

Publication type:

journal article

Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes.

Published in:

2002

By:

Musi, Nicolas;
Hirshman, Michael F.;
Nygren, Jonas;
Svanfeldt, Monika;
Bavenholm, Peter;
Rooyackers, Olav;
Zhou, Gaochao;
Williamson, Joanne M.;
Ljunqvist, Olle;
Efendic, Suad;
Moller, David E.;
Thorell, Anders;
Goodyear, Laurie J.

Publication type:

journal article

Effect of AICAR treatment on glycogen metabolism in skeletal muscle.

Published in:

2002

By:

Aschenbach, William G.;
Hirshman, Michael F.;
Nobuharu Fujii;
Kei Sakamoto;
Howlett, Kirsten F.;
Goodyear, Laurie J.;
Fujii, Nobuharu;
Sakamoto, Kei

Publication type:

journal article

Insulin signaling after exercise in insulin receptor substrate-2-deficient mice.

Published in:

2002

By:

Howlett, Kirsten F.;
Sakamoto, Kei;
Hirshman, Michael F.;
Aschenbach, William G.;
Dow, Matthew;
White, Morris F.;
Goodyear, Laurie J.

Publication type:

journal article

AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise.

Published in:

2001

By:

Musi, Nicolas;
Fujii, Nobuharu;
Hirshman, Michael F.;
Ekberg, Ingvar;
Froberg, Sven;
Ljungqvist, Olle;
Thorell, Anders;
Goodyear, Laurie J.;
Musi, N;
Fujii, N;
Hirshman, M F;
Ekberg, I;
Fröberg, S;
Ljungqvist, O;
Thorell, A;
Goodyear, L J

Publication type:

journal article

Nitric oxide increases glucose uptake through a mechanism that is distinct from the insulin and contraction pathways in rat skeletal muscle.

Published in:

2001

By:

Higaki, Yasuki;
Hirshman, Michael F.;
Fujii, Nobuharu;
Goodyear, Laurie J.;
Higaki, Y;
Hirshman, M F;
Fujii, N;
Goodyear, L J

Publication type:

journal article

Metabolic Stress and Altered Glucose Transport.

Published in:

Diabetes, 2000, v. 49, n. 4, p. 527, doi. 10.2337/diabetes.49.4.527

By:

Hayashi, Tatsuya;
Hirshman, Michael F.;
Fujii, Nobuharu;
Habinowski, Susan A.;
Witters, Lee A.;
Goodyear, Laurie J.

Publication type:

Article

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

Published in:

1999

By:

Kurth-Kraczek, Emily J.;
Hirshman, Michael F.;
Goodyear, Laurie J.;
Winder, William W.;
Kurth-Kraczek, E J;
Hirshman, M F;
Goodyear, L J;
Winder, W W

Publication type:

journal article

Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes.

Published in:

1999

By:

Kennedy, John W.;
Hirshman, Michael F.;
Gervino, Ernest V.;
Ocel, Jeffrey V.;
Forse, R. Armour;
Hoenig, Stephen J.;
Aronson, Doron;
Goodyear, Laurie J.;
Horton, Edward S.;
Kennedy, J W;
Hirshman, M F;
Gervino, E V;
Ocel, J V;
Forse, R A;
Hoenig, S J;
Aronson, D;
Goodyear, L J;
Horton, E S

Publication type:

journal article

Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats.

Published in:

1999

By:

Giorgino, Francesco;
Logoluso, Francesco;
Davalli, Alberto M.;
Napoli, Raffaele;
Laviola, Luigi;
Hirshman, Michael F.;
Horton, Edward S.;
Weir, Gordon C.;
Smith, Robert J.;
Giorgino, F;
Logoluso, F;
Davalli, A M;
Napoli, R;
Laviola, L;
Hirshman, M F;
Horton, E S;
Weir, G C;
Smith, R J

Publication type:

journal article

Epinephrine and insulin stimulate different mitogen-activated protein kinase signaling pathways in rat skeletal muscle.

Published in:

1998

By:

Napoli, Raffaele;
Gibson, Lindsay;
Hirshman, Michael F.;
Boppart, Marni D.;
Dufresne, Scott D.;
Horton, Edward S.;
Goodyear, Laurie J.;
Napoli, R;
Gibson, L;
Hirshman, M F;
Boppart, M D;
Dufresne, S D;
Horton, E S;
Goodyear, L J

Publication type:

journal article

Evidence for 5' AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport.

Published in:

1998

By:

Hayashi, Tatsuya;
Hirshman, Michael F.;
Kurth, E.J.;
Winder, W.W.;
Goodyear, L.J.;
Hayashi, T;
Hirshman, M F

Publication type:

journal article

CL-316, 243, a β<sub>2</sub>-Specific Adrenoceptor Agonist, Enhances Insulin-Stimulated Glucose Disposal in Nonobese Rats.

Published in:

Diabetes, 1997, v. 46, n. 8, p. 1257, doi. 10.2337/diab.46.8.1257

By:

De Souza, Christopher J.;
Hirshman, Michael F.;
Horton, Edward S.

Publication type:

Article

Glucose ingestion causes GLUT4 translocation in human skeletal muscle.

Published in:

1996

By:

Goodyear, Laurie J.;
Hirshman, Michael F.;
Napoli, Raffaele;
Calles, Jorge;
Markuns, Jeffrey F.;
Ljungqvist, Olle;
Horton, Edward S.;
Goodyear, L J;
Hirshman, M F;
Napoli, R;
Calles, J;
Markuns, J F;
Ljungqvist, O;
Horton, E S

Publication type:

journal article