Works by Hirsch, Anna K. H.

Results: 93

Facile Production of the Pseudomonas aeruginosa Virulence Factor LasB in Escherichia coli for Structure‐Based Drug Design.

Published in:

ChemBioChem, 2023, v. 24, n. 17, p. 1, doi. 10.1002/cbic.202300185

By:

Kolling, Dominik;
Haupenthal, Jörg;
Hirsch, Anna K. H.;
Koehnke, Jesko

Publication type:

Article

Phage Display on the Anti-infective Target 1-Deoxy- d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor.

Published in:

ChemBioChem, 2018, v. 19, n. 1, p. 58, doi. 10.1002/cbic.201700402

By:

Marcozzi, Alessio;
Masini, Tiziana;
Zhu, Di;
Pesce, Diego;
Illarionov, Boris;
Fischer, Markus;
Herrmann, Andreas;
Hirsch, Anna K. H.

Publication type:

Article

Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.

Published in:

ChemBioChem, 2015, v. 16, n. 5, p. 819, doi. 10.1002/cbic.201402673

By:

Swier, Lotteke J. Y. M.;
Monjas, Leticia;
Guskov, Albert;
de Voogd, Alrik R.;
Erkens, Guus B.;
Slotboom, Dirk J.;
Hirsch, Anna K. H.

Publication type:

Article

Replacement of an Indole Scaffold Targeting Human 15‐Lipoxygenase‐1 Using Combinatorial Chemistry.

Published in:

Helvetica Chimica Acta, 2019, v. 102, n. 5, p. N.PAG, doi. 10.1002/hlca.201900040

By:

Prismawan, Deka;
van der Vlag, Ramon;
Guo, Hao;
Dekker, Frank J.;
Hirsch, Anna K. H.

Publication type:

Article

Trendbericht Biochemie 2017: Proteinvermittelte dynamische kombinatorische Chemie.

Published in:

Nachrichten aus der Chemie, 2018, v. 66, n. 3, p. 281, doi. 10.1002/nadc.20184071734

By:

Hirsch, Anna K. H.

Publication type:

Article

Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50671-9

By:

Gawriljuk, Victor O.;
Godoy, Andre S.;
Oerlemans, Rick;
Welker, Luise A. T.;
Hirsch, Anna K. H.;
Groves, Matthew R.

Publication type:

Article

Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS‐CoV‐2.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 4, p. 1, doi. 10.1002/chem.202403390

By:

Jumde, Ravindra P.;
Jézéquel, Gwenaëlle;
Saramago, Margarida;
Frank, Nicolas;
Adam, Sebastian;
Cunha, Marta V.;
Bader, Chantal D.;
Gunesch, Antonia P.;
Köhler, Natalie M.;
Johannsen, Sandra;
Bousis, Spyridon;
Pietschmann, Thomas;
Matos, Rute G.;
Müller, Rolf;
Arraiano, Cecília M.;
Hirsch, Anna K. H.

Publication type:

Article

Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery**.

Published in:

Angewandte Chemie, 2024, v. 136, n. 4, p. 1, doi. 10.1002/ange.202308131

By:

Afanasenko, Anastasiia M.;
Wu, Xianyuan;
De Santi, Alessandra;
Elgaher, Walid A. M.;
Kany, Andreas M.;
Shafiei, Roya;
Schulze, Marie‐Sophie;
Schulz, Thomas F.;
Haupenthal, Jörg;
Hirsch, Anna K. H.;
Barta, Katalin

Publication type:

Article

Korrektur der absoluten Konfiguration von Chelocardin und Amidochelocardin.

Published in:

Angewandte Chemie, 2023, v. 135, n. 40, p. 1, doi. 10.1002/ange.202306437

By:

Sikandar, Asfandyar;
Popoff, Alexander;
Jumde, Ravindra P.;
Mándi, Attila;
Kaur, Amninder;
Elgaher, Walid A. M.;
Rosenberger, Lara;
Hüttel, Stephan;
Jansen, Rolf;
Hunter, Maja;
Köhnke, Jesko;
Hirsch, Anna K. H.;
Kurtán, Tibor;
Müller, Rolf

Publication type:

Article

Substratinspirierte Fragment‐Fusion und ‐Erweiterung führt zu wirksamen LasB‐Inhibitoren.

Published in:

Angewandte Chemie, 2022, v. 134, n. 5, p. 1, doi. 10.1002/ange.202112295

By:

Kaya, Cansu;
Walter, Isabell;
Yahiaoui, Samir;
Sikandar, Asfandyar;
Alhayek, Alaa;
Konstantinović, Jelena;
Kany, Andreas M.;
Haupenthal, Jörg;
Köhnke, Jesko;
Hartmann, Rolf W.;
Hirsch, Anna K. H.

Publication type:

Article

Inverting Small Molecule–Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H→F Bioisosterism.

Published in:

Angewandte Chemie, 2019, v. 131, n. 32, p. 11106, doi. 10.1002/ange.201905452

By:

Bentler, Patrick;
Bergander, Klaus;
Daniliuc, Constantin G.;
Mück‐Lichtenfeld, Christian;
Jumde, Ravindra P.;
Hirsch, Anna K. H.;
Gilmour, Ryan

Publication type:

Article

Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin‐Wound Infections.

Published in:

Advanced Therapeutics, 2022, v. 5, n. 3, p. 1, doi. 10.1002/adtp.202100222

By:

Alhayek, Alaa;
Khan, Essak S.;
Schönauer, Esther;
Däinghaus, Tobias;
Shafiei, Roya;
Voos, Katrin;
Han, Mitchell K. L.;
Ducho, Christian;
Posselt, Gernot;
Wessler, Silja;
Brandstetter, Hans;
Haupenthal, Jörg;
del Campo, Aránzazu;
Hirsch, Anna K. H.

Publication type:

Article

Energy‐Coupling Factor Transporters as Novel Antimicrobial Targets.

Published in:

Advanced Therapeutics, 2019, v. 2, n. 2, p. N.PAG, doi. 10.1002/adtp.201800066

By:

Bousis, Spyridon;
Setyawati, Inda;
Diamanti, Eleonora;
Slotboom, Dirk J.;
Hirsch, Anna K. H.

Publication type:

Article

Structure of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Synthase in Complex with Butylacetylphosphonate.

Published in:

Crystals (2073-4352), 2023, v. 13, n. 5, p. 737, doi. 10.3390/cryst13050737

By:

Gawriljuk, Victor Oliveira;
Oerlemans, Rick;
Gierse, Robin M.;
Jotwani, Riya;
Hirsch, Anna K. H.;
Groves, Matthew R.

Publication type:

Article

Bacteriomimetic Liposomes Improve Antibiotic Activity of a Novel Energy-Coupling Factor Transporter Inhibitor.

Published in:

Pharmaceutics, 2022, v. 14, n. 1, p. 4, doi. 10.3390/pharmaceutics14010004

By:

Drost, Menka;
Diamanti, Eleonora;
Fuhrmann, Kathrin;
Goes, Adriely;
Shams, Atanaz;
Haupenthal, Jörg;
Koch, Marcus;
Hirsch, Anna K. H.;
Fuhrmann, Gregor

Publication type:

Article

Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 5, p. 632, doi. 10.3390/ph15050632

By:

Hamdy, Jehad;
Emadeldin, Nouran;
Hamed, Mostafa M.;
Frakolaki, Efseveia;
Katsamakas, Sotirios;
Vassilaki, Niki;
Zoidis, Grigoris;
Hirsch, Anna K. H.;
Abdel-Halim, Mohammad;
Abadi, Ashraf H.

Publication type:

Article

Combinatorial Screening for Specific Drug Solubilizers with Switchable Release Profiles.

Published in:

Macromolecular Bioscience, 2015, v. 15, n. 1, p. 82, doi. 10.1002/mabi.201400443

By:

Wieczorek, Sebastian;
Vigne, Sara;
Masini, Tiziana;
Ponader, Daniela;
Hartmann, Laura;
Hirsch, Anna K. H.;
Börner, Hans G.

Publication type:

Article

Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 170, doi. 10.1080/14756366.2016.1201812

By:

Masini, Tiziana;
Birkaya, Barbara;
van Dijk, Simon;
Mondal, Milon;
Hekelaar, Johan;
Jäger, Manuel;
Terwisscha van Scheltinga, Anke C.;
Patel, Mulchand S.;
Hirsch, Anna K. H.;
Moman, Edelmiro

Publication type:

Article

The Structures and Binding Modes of Small-Molecule Inhibitors of Pseudomonas aeruginosa Elastase LasB.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 8, p. N.PAG, doi. 10.3390/antibiotics11081060

By:

Camberlein, Virgyl;
Jézéquel, Gwenaëlle;
Haupenthal, Jörg;
Hirsch, Anna K. H.

Publication type:

Article

Correction: Fries et al. Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin A Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. Int. J. Mol. Sci. 2023, 24 , 12791.

Published in:

2024

By:

Fries, Franziska;
Kany, Andreas M.;
Rasheed, Sari;
Hirsch, Anna K. H.;
Müller, Rolf;
Herrmann, Jennifer

Publication type:

Correction Notice

Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin a Using a Staphylococcus aureus Infection Model in Zebrafish Embryos.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12791, doi. 10.3390/ijms241612791

By:

Fries, Franziska;
Kany, Andreas M.;
Rasheed, Sari;
Hirsch, Anna K. H.;
Müller, Rolf;
Herrmann, Jennifer

Publication type:

Article

An Efficient Way to Screen Inhibitors of Energy-Coupling Factor (ECF) Transporters in a Bacterial Uptake Assay.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2637, doi. 10.3390/ijms23052637

By:

Bousis, Spyridon;
Winkler, Steffen;
Haupenthal, Jörg;
Fulco, Francesco;
Diamanti, Eleonora;
Hirsch, Anna K. H.

Publication type:

Article

Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 8, p. 19184, doi. 10.3390/ijms160819184

By:

Hartman, Alwin M.;
Mondal, Milon;
Radeva, Nedyalka;
Klebe, Gerhard;
Hirsch, Anna K. H.

Publication type:

Article

Proteoid Dynamers with Tunable Properties.

Published in:

Advanced Functional Materials, 2016, v. 26, n. 34, p. 6297, doi. 10.1002/adfm.201601612

By:

Liu, Yun;
Stuart, Marc C. A.;
Buhler, Eric;
Lehn, Jean‐Marie;
Hirsch, Anna K. H.

Publication type:

Article

Imidazole- and Benzimidazole-Based Inhibitors of the Kinase IspE: Targeting the Substrate-Binding Site and the Triphosphate-Binding Loop of the ATP Site.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 6, p. 1068, doi. 10.1002/ejoc.201201467

By:

Mombelli, Paolo;
Le Chapelain, Camille;
Munzinger, Noah;
Joliat, Evelyne;
Illarionov, Boris;
Schweizer, W. Bernd;
Hirsch, Anna K. H.;
Fischer, Markus;
Bacher, Adelbert;
Diederich, François

Publication type:

Article

Exploring the Ribose Sub-Pocket of the Substrate-Binding Site in Escherichia coli IspE: Structure-Based Design, Synthesis, and Biological Evaluation of Cytosines and Cytosine Analogues.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 17, p. 3278, doi. 10.1002/ejoc.201200296

By:

Schütz, Andri P.;
Osawa, Sho;
Mathis, Jennifer;
Hirsch, Anna K. H.;
Bernet, Bruno;
Illarionov, Boris;
Fischer, Markus;
Bacher, Adelbert;
Diederich, François

Publication type:

Article

Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 19, p. 1, doi. 10.1002/anie.202319765

By:

Hofer, Walter;
Deschner, Felix;
Jézéquel, Gwenaëlle;
Pessanha de Carvalho, Laìs;
Abdel‐Wadood, Noran;
Pätzold, Linda;
Bernecker, Steffen;
Morgenstern, Bernd;
Kany, Andreas M.;
Große, Miriam;
Stadler, Marc;
Bischoff, Markus;
Hirsch, Anna K. H.;
Held, Jana;
Herrmann, Jennifer;
Müller, Rolf

Publication type:

Article

Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery**.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 4, p. 1, doi. 10.1002/anie.202308131

By:

Afanasenko, Anastasiia M.;
Wu, Xianyuan;
De Santi, Alessandra;
Elgaher, Walid A. M.;
Kany, Andreas M.;
Shafiei, Roya;
Schulze, Marie‐Sophie;
Schulz, Thomas F.;
Haupenthal, Jörg;
Hirsch, Anna K. H.;
Barta, Katalin

Publication type:

Article

Revision of the Absolute Configurations of Chelocardin and Amidochelocardin.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 40, p. 1, doi. 10.1002/anie.202306437

By:

Sikandar, Asfandyar;
Popoff, Alexander;
Jumde, Ravindra P.;
Mándi, Attila;
Kaur, Amninder;
Elgaher, Walid A. M.;
Rosenberger, Lara;
Hüttel, Stephan;
Jansen, Rolf;
Hunter, Maja;
Köhnke, Jesko;
Hirsch, Anna K. H.;
Kurtán, Tibor;
Müller, Rolf

Publication type:

Article

Substrate‐Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 5, p. 1, doi. 10.1002/anie.202112295

By:

Kaya, Cansu;
Walter, Isabell;
Yahiaoui, Samir;
Sikandar, Asfandyar;
Alhayek, Alaa;
Konstantinović, Jelena;
Kany, Andreas M.;
Haupenthal, Jörg;
Köhnke, Jesko;
Hartmann, Rolf W.;
Hirsch, Anna K. H.

Publication type:

Article

Inverting Small Molecule–Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H→F Bioisosterism.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 32, p. 10990, doi. 10.1002/anie.201905452

By:

Bentler, Patrick;
Bergander, Klaus;
Daniliuc, Constantin G.;
Mück‐Lichtenfeld, Christian;
Jumde, Ravindra P.;
Hirsch, Anna K. H.;
Gilmour, Ryan

Publication type:

Article

Expression and characterization of pantothenate energy‐coupling factor transporters as an anti‐infective drug target.

Published in:

Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 11, p. 1, doi. 10.1002/pro.5195

By:

Shams, Atanaz;
Bousis, Spyridon;
Diamanti, Eleonora;
Elgaher, Walid A. M.;
Zeimetz, Lucie;
Haupenthal, Jörg;
Slotboom, Dirk J.;
Hirsch, Anna K. H.

Publication type:

Article

Entdeckung von Fragmenten durch Röntgenkristallografisches Screening, die auf die CTP‐Bindungsstelle von Pseudomonas Aeruginosa IspD Abzielen.

Published in:

Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202414615

By:

Willocx, Daan;
D'Auria, Lucia;
Walsh, Danica;
Scherer, Hugo;
Alhayek, Alaa;
Hamed, Mostafa M.;
Borel, Franck;
Diamanti, Eleonora;
Hirsch, Anna K. H.

Publication type:

Article

Funktionalisierung von Chlorotonilen: Dehalogenil als vielversprechende Leitverbindung für die in vivo‐Anwendung.

Published in:

Angewandte Chemie, 2024, v. 136, n. 19, p. 1, doi. 10.1002/ange.202319765

By:

Hofer, Walter;
Deschner, Felix;
Jézéquel, Gwenaëlle;
Pessanha de Carvalho, Laìs;
Abdel‐Wadood, Noran;
Pätzold, Linda;
Bernecker, Steffen;
Morgenstern, Bernd;
Kany, Andreas M.;
Große, Miriam;
Stadler, Marc;
Bischoff, Markus;
Hirsch, Anna K. H.;
Held, Jana;
Herrmann, Jennifer;
Müller, Rolf

Publication type:

Article

Targeting Extracellular Bacterial Proteases for the Development of Novel Antivirulence Agents.

Published in:

Chimia, 2022, v. 76, n. 5, p. 402, doi. 10.2533/chimia.2022.402

By:

Kaya, Cansu;
Hirsch, Anna K. H.

Publication type:

Article

Dynamic Proteoids Generated From Dipeptide‐Based Monomers.

Published in:

Macromolecular Rapid Communications, 2018, v. 39, n. 13, p. 1, doi. 10.1002/marc.201800099

By:

Liu, Yun;
Stuart, Marc C. A.;
Buhler, Eric;
Hirsch, Anna K. H.

Publication type:

Article

Frontispiece: Protein‐Templated Hit Identification through an Ugi Four‐Component Reaction.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 64, p. 1, doi. 10.1002/chem.202086462

By:

Mancini, Federica;
Unver, M. Yagiz;
Elgaher, Walid A. M.;
Jumde, Varsha R.;
Alhayek, Alaa;
Lukat, Peer;
Herrmann, Jennifer;
Witte, Martin D.;
Köck, Matthias;
Blankenfeldt, Wulf;
Müller, Rolf;
Hirsch, Anna K. H.

Publication type:

Article

Protein‐Templated Hit Identification through an Ugi Four‐Component Reaction**.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 64, p. 14585, doi. 10.1002/chem.202002250

By:

Mancini, Federica;
Unver, M. Yagiz;
Elgaher, Walid A. M.;
Jumde, Varsha R.;
Alhayek, Alaa;
Lukat, Peer;
Herrmann, Jennifer;
Witte, Martin D.;
Köck, Matthias;
Blankenfeldt, Wulf;
Müller, Rolf;
Hirsch, Anna K. H.

Publication type:

Article

Comparing the Self‐Assembly of Sexiphenyl‐Dicarbonitrile on Graphite and Graphene on Cu(111).

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 19, p. 5065, doi. 10.1002/chem.201806312

By:

Schmidt, Nico;
Li, Jun;
Gottardi, Stefano;
Moreno‐Lopez, Juan Carlos;
Enache, Mihaela;
Monjas, Leticia;
van der Vlag, Ramon;
Havenith, Remco W. A.;
Hirsch, Anna K. H.;
Stöhr, Meike

Publication type:

Article

Lipid-DNAs as Solubilizers of mTHPC.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 4, p. 798, doi. 10.1002/chem.201705206

By:

Yun Liu;
Vries, Jan Willem de;
Qing Liu;
Hartman, Alwin M.;
Wieland, Gerhard D.;
Wieczorek, Sebastian;
Bçrner, Hans G.;
Wiehe, Arno;
Buhler, Eric;
Stuart, Marc C. A.;
Browne, Wesley R.;
Herrmann, Andreas;
Hirsch, Anna K. H.

Publication type:

Article

Saccharide-Containing Dynamic Proteoids.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 64, p. 16162, doi. 10.1002/chem.201703584

By:

Liu, Yun;
Stuart, Marc C. A.;
Witte, Martin D.;
Buhler, Eric;
Hirsch, Anna K. H.

Publication type:

Article

Total Synthesis of (−)-Doliculide, Structure-Activity Relationship Studies and Its Binding to F-Actin.

Published in:

ChemBioChem, 2012, v. 13, n. 17, p. 2537, doi. 10.1002/cbic.201200512

By:

Matcha, Kiran;
Madduri, Ashoka V. R.;
Roy, Sayantani;
Ziegler, Slava;
Waldmann, Herbert;
Hirsch, Anna K. H.;
Minnaard, Adriaan J.

Publication type:

Article

Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32084-z

By:

Vasile, Francesca;
Della Volpe, Serena;
Ambrosio, Francesca Alessandra;
Costa, Giosuè;
Unver, M. Yagiz;
Zucal, Chiara;
Rossi, Daniela;
Martino, Emanuela;
Provenzani, Alessandro;
Hirsch, Anna K. H.;
Alcaro, Stefano;
Potenza, Donatella;
Collina, Simona

Publication type:

Article

Protein‐Templated Dynamic Combinatorial Chemistry: Brief Overview and Experimental Protocol.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 22, p. 3581, doi. 10.1002/ejoc.201900327

By:

Hartman, Alwin M.;
Gierse, Robin M.;
Hirsch, Anna K. H.

Publication type:

Article

Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach.

Published in:

ChemMedChem, 2020, v. 15, n. 8, p. 680, doi. 10.1002/cmdc.202000024

By:

Konstantinidou, Markella;
Magari, Francesca;
Sutanto, Fandi;
Haupenthal, Jörg;
Jumde, Varsha R.;
Ünver, M. Yagiz;
Heine, Andreas;
Camacho, Carlos Jamie;
Hirsch, Anna K. H.;
Klebe, Gerhard;
Dömling, Alexander

Publication type:

Article

Optimized Inhibitors of MDM2 via an Attempted Protein‐Templated Reductive Amination.

Published in:

ChemMedChem, 2020, v. 15, n. 4, p. 370, doi. 10.1002/cmdc.201900574

By:

Vlag, Ramon;
Yagiz Unver, M.;
Felicetti, Tommaso;
Twarda‐Clapa, Aleksandra;
Kassim, Fatima;
Ermis, Cagdas;
Neochoritis, Constantinos G.;
Musielak, Bogdan;
Labuzek, Beata;
Dömling, Alexander;
Holak, Tad A.;
Hirsch, Anna K. H.

Publication type:

Article

Rational Adaptation of L3MBTL1 Inhibitors to Create Small‐Molecule Cbx7 Antagonists.

Published in:

ChemMedChem, 2019, v. 14, n. 15, p. 1444, doi. 10.1002/cmdc.201900021

By:

Simhadri, Chakravarthi;
Daze, Kevin D.;
Douglas, Sarah F.;
Milosevich, Natalia;
Monjas, Leticia;
Dev, Amarjot;
Brown, Tyler M.;
Hirsch, Anna K. H.;
Wulff, Jeremy E.;
Hof, Fraser

Publication type:

Article

Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin.

Published in:

ChemMedChem, 2018, v. 13, n. 21, p. 2266, doi. 10.1002/cmdc.201800446

By:

Jumde, Varsha R.;
Mondal, Milon;
Gierse, Robin M.;
Unver, M. Yagiz;
Magari, Francesca;
van Lier, Roos C. W.;
Heine, Andreas;
Klebe, Gerhard;
Hirsch, Anna K. H.

Publication type:

Article

Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S-Component of the Energy-Coupling Factor Transporter for Thiamine.

Published in:

ChemMedChem, 2017, v. 12, n. 20, p. 1693, doi. 10.1002/cmdc.201700440

By:

Monjas, Leticia;
Swier, Lotteke J. Y. M.;
Setyawati, Inda;
Slotboom, Dirk J.;
Hirsch, Anna K. H.

Publication type:

Article

Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase IspE of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis.

Published in:

ChemMedChem, 2008, v. 3, n. 1, p. 91, doi. 10.1002/cmdc.200700208

By:

Crane, Christine M.;
Hirsch, Anna K. H.;
Alphey, Magnus S.;
Sgraja, Tanja;
Lauw, Susan;
Illarionova, Victoria;
Rohdich, Felix;
Eisenreich, Wolfgang;
Hunter, William N.;
Bacher, Adelbert;
Diederich, François

Publication type:

Article