Works by Hirsch, Anna K. H.
Results: 89
Funktionalisierung von Chlorotonilen: Dehalogenil als vielversprechende Leitverbindung für die in vivo‐Anwendung.
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- Angewandte Chemie, 2024, v. 136, n. 19, p. 1, doi. 10.1002/ange.202319765
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- Article
Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery**.
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- Angewandte Chemie, 2024, v. 136, n. 4, p. 1, doi. 10.1002/ange.202308131
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- Article
Korrektur der absoluten Konfiguration von Chelocardin und Amidochelocardin.
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- Angewandte Chemie, 2023, v. 135, n. 40, p. 1, doi. 10.1002/ange.202306437
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- Article
Substratinspirierte Fragment‐Fusion und ‐Erweiterung führt zu wirksamen LasB‐Inhibitoren.
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- Angewandte Chemie, 2022, v. 134, n. 5, p. 1, doi. 10.1002/ange.202112295
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- Article
Inverting Small Molecule–Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H→F Bioisosterism.
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- Angewandte Chemie, 2019, v. 131, n. 32, p. 11106, doi. 10.1002/ange.201905452
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- Article
Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 170, doi. 10.1080/14756366.2016.1201812
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- Article
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner.
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- PLoS Pathogens, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.ppat.1011506
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- Article
Facile Production of the Pseudomonas aeruginosa Virulence Factor LasB in Escherichia coli for Structure‐Based Drug Design.
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- ChemBioChem, 2023, v. 24, n. 17, p. 1, doi. 10.1002/cbic.202300185
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- Article
Phage Display on the Anti-infective Target 1-Deoxy- d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor.
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- ChemBioChem, 2018, v. 19, n. 1, p. 58, doi. 10.1002/cbic.201700402
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- Article
Nonphosphate Inhibitors of IspE Protein, a Kinase in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy.
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- ChemMedChem, 2007, v. 2, n. 6, p. 806, doi. 10.1002/cmdc.200700014
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- Article
Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.
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- ChemBioChem, 2015, v. 16, n. 5, p. 819, doi. 10.1002/cbic.201402673
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- Article
Total Synthesis of (−)-Doliculide, Structure-Activity Relationship Studies and Its Binding to F-Actin.
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- ChemBioChem, 2012, v. 13, n. 17, p. 2537, doi. 10.1002/cbic.201200512
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- Article
Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin‐Wound Infections.
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- Advanced Therapeutics, 2022, v. 5, n. 3, p. 1, doi. 10.1002/adtp.202100222
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- Article
Energy‐Coupling Factor Transporters as Novel Antimicrobial Targets.
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- Advanced Therapeutics, 2019, v. 2, n. 2, p. N.PAG, doi. 10.1002/adtp.201800066
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- Article
Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application.
- Published in:
- Angewandte Chemie International Edition, 2024, v. 63, n. 19, p. 1, doi. 10.1002/anie.202319765
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- Publication type:
- Article
Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery**.
- Published in:
- Angewandte Chemie International Edition, 2024, v. 63, n. 4, p. 1, doi. 10.1002/anie.202308131
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- Publication type:
- Article
Proteoid Dynamers with Tunable Properties.
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- Advanced Functional Materials, 2016, v. 26, n. 34, p. 6297, doi. 10.1002/adfm.201601612
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- Article
Author Correction: Identification of inhibitors targeting the energy-coupling factor (ECF) transporters.
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- 2024
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- Correction Notice
Identification of inhibitors targeting the energy-coupling factor (ECF) transporters.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05555-x
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- Article
Replacement of an Indole Scaffold Targeting Human 15‐Lipoxygenase‐1 Using Combinatorial Chemistry.
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- Helvetica Chimica Acta, 2019, v. 102, n. 5, p. N.PAG, doi. 10.1002/hlca.201900040
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- Article
First crystal structures of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-11205-9
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- Article
Trendbericht Biochemie 2017: Proteinvermittelte dynamische kombinatorische Chemie.
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- Nachrichten aus der Chemie, 2018, v. 66, n. 3, p. 281, doi. 10.1002/nadc.20184071734
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- Article
Protein‐Templated Dynamic Combinatorial Chemistry: Brief Overview and Experimental Protocol.
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- European Journal of Organic Chemistry, 2019, v. 2019, n. 22, p. 3581, doi. 10.1002/ejoc.201900327
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- Article
Revision of the Absolute Configurations of Chelocardin and Amidochelocardin.
- Published in:
- Angewandte Chemie International Edition, 2023, v. 62, n. 40, p. 1, doi. 10.1002/anie.202306437
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- Publication type:
- Article
Substrate‐Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors.
- Published in:
- Angewandte Chemie International Edition, 2022, v. 61, n. 5, p. 1, doi. 10.1002/anie.202112295
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- Publication type:
- Article
Inverting Small Molecule–Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H→F Bioisosterism.
- Published in:
- Angewandte Chemie International Edition, 2019, v. 58, n. 32, p. 10990, doi. 10.1002/anie.201905452
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- Publication type:
- Article
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling.
- Published in:
- FASEB Journal, 2020, v. 34, n. 1, p. 316, doi. 10.1096/fj.201901314RR
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- Article
Sprühtrocknung inhalierbarer, multifunktionaler Formulierungen zur Behandlung von Biofilmen bei Mukoviszidose.
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- Pharmazeutische Industrie (Pharmind), 2021, v. 83, n. 10, p. 1381
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- Article
Sprühtrocknung inhalierbarer, multifunktionaler Formulierungen zur Behandlung von Biofilmen bei Mukoviszidose.
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- Pharmazeutische Industrie (Pharmind), 2021, v. 83, n. 9, p. 1246
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- Article
Structure of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Synthase in Complex with Butylacetylphosphonate.
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- Crystals (2073-4352), 2023, v. 13, n. 5, p. 737, doi. 10.3390/cryst13050737
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- Article
Front Cover: Exploring the Translational Gap of a Novel Class of Escherichia coli IspE Inhibitors (ChemMedChem 19/2023).
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- ChemMedChem, 2023, v. 18, n. 19, p. 1, doi. 10.1002/cmdc.202300546
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- Article
Exploring the Translational Gap of a Novel Class of Escherichia coli IspE Inhibitors.
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- ChemMedChem, 2023, v. 18, n. 19, p. 1, doi. 10.1002/cmdc.202300346
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- Article
Not Every Hit‐Identification Technique Works on 1‐Deoxy‐d‐Xylulose 5‐Phosphate Synthase (DXPS): Making the Most of a Virtual Screening Campaign.
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- ChemMedChem, 2023, v. 18, n. 11, p. 1, doi. 10.1002/cmdc.202200590
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- Article
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class.
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- ChemMedChem, 2022, v. 17, n. 5, p. 1, doi. 10.1002/cmdc.202100679
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- Article
Search for the Active Ingredients from a 2‐Aminothiazole DMSO Stock Solution with Antimalarial Activity.
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- ChemMedChem, 2021, v. 16, n. 13, p. 2089, doi. 10.1002/cmdc.202100067
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- Article
Phosphonate as a Stable Zinc‐Binding Group for "Pathoblocker" Inhibitors of Clostridial Collagenase H (ColH).
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- ChemMedChem, 2021, v. 16, n. 8, p. 1257, doi. 10.1002/cmdc.202000994
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- Article
Front Cover: Phosphonate as a Stable Zinc‐Binding Group for "Pathoblocker" Inhibitors of Clostridial Collagenase H (ColH) (ChemMedChem 8/2021).
- Published in:
- ChemMedChem, 2021, v. 16, n. 8, p. 1198, doi. 10.1002/cmdc.202100229
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- Article
Cover Feature: Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase (ChemMedChem 1/2021).
- Published in:
- ChemMedChem, 2021, v. 16, n. 1, p. 3, doi. 10.1002/cmdc.202000959
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- Article
François Diederich – In Memoriam**.
- Published in:
- ChemMedChem, 2021, v. 16, n. 1, p. 11, doi. 10.1002/cmdc.202000920
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- Article
Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase.
- Published in:
- ChemMedChem, 2021, v. 16, n. 1, p. 113, doi. 10.1002/cmdc.202000222
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- Article
Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach.
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- ChemMedChem, 2020, v. 15, n. 8, p. 680, doi. 10.1002/cmdc.202000024
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- Article
Optimized Inhibitors of MDM2 via an Attempted Protein‐Templated Reductive Amination.
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- ChemMedChem, 2020, v. 15, n. 4, p. 370, doi. 10.1002/cmdc.201900574
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- Article
Rational Adaptation of L3MBTL1 Inhibitors to Create Small‐Molecule Cbx7 Antagonists.
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- ChemMedChem, 2019, v. 14, n. 15, p. 1444, doi. 10.1002/cmdc.201900021
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- Article
Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin.
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- ChemMedChem, 2018, v. 13, n. 21, p. 2266, doi. 10.1002/cmdc.201800446
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- Publication type:
- Article
Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S-Component of the Energy-Coupling Factor Transporter for Thiamine.
- Published in:
- ChemMedChem, 2017, v. 12, n. 20, p. 1693, doi. 10.1002/cmdc.201700440
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- Publication type:
- Article
Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase IspE of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis.
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- ChemMedChem, 2008, v. 3, n. 1, p. 91, doi. 10.1002/cmdc.200700208
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- Article
Correction: Fries et al. Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin A Using a Staphylococcus aureus Infection Model in Zebrafish Embryos. Int. J. Mol. Sci. 2023, 24 , 12791.
- Published in:
- 2024
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- Publication type:
- Correction Notice
Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin a Using a Staphylococcus aureus Infection Model in Zebrafish Embryos.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12791, doi. 10.3390/ijms241612791
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- Article
An Efficient Way to Screen Inhibitors of Energy-Coupling Factor (ECF) Transporters in a Bacterial Uptake Assay.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2637, doi. 10.3390/ijms23052637
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- Article
Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin.
- Published in:
- International Journal of Molecular Sciences, 2015, v. 16, n. 8, p. 19184, doi. 10.3390/ijms160819184
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- Article