Works by Hiroyuki Ohba

Results: 46

In vivo TSPO and cannabinoid receptor type 2 availability early in post-stroke neuroinflammation in rats: a positron emission tomography study.

Published in:

2017

By:

Teruyo Hosoya;
Dai Fukumoto;
Takeharu Kakiuchi;
Shingo Nishiyama;
Shigeyuki Yamamoto;
Hiroyuki Ohba;
Hideo Tsukada;
Takatoshi Ueki;
Kohji Sato;
Yasuomi Ouchi;
Hosoya, Teruyo;
Fukumoto, Dai;
Kakiuchi, Takeharu;
Nishiyama, Shingo;
Yamamoto, Shigeyuki;
Ohba, Hiroyuki;
Tsukada, Hideo;
Ueki, Takatoshi;
Sato, Kohji;
Ouchi, Yasuomi

Publication type:

journal article

Effect of MPTP on Serotonergic Neuronal Systems and Mitochondrial Complex I Activity in the Living Brain: A PET Study on Conscious Rhesus Monkeys.

Published in:

Journal of Nuclear Medicine, 2017, v. 58, n. 7, p. 1111, doi. 10.2967/jnumed.116.189159

By:

Masakatsu Kanazawa;
Hiroyuki Ohba;
Shingo Nishiyama;
Takeharu Kakiuchi;
Hideo Tsukada

Publication type:

Article

In Vivo Evaluation of 11C-Preladenant for PET Imaging of Adenosine A2A Receptors in the Conscious Monkey.

Published in:

Journal of Nuclear Medicine, 2017, v. 58, n. 5, p. 762, doi. 10.2967/jnumed.116.182410

By:

Xiaoyun Zhou;
Boellaard, Ronald;
Kiichi Ishiwata;
Muneyuki Sakata;
Dierckx, Rudi A. J. O.;
de Jong, Johan R.;
Shingo Nishiyama;
Hiroyuki Ohba;
Hideo Tsukada;
de Vries, Erik F. J.;
Elsinga, Philip H.

Publication type:

Article

PET Imaging of Mitochondrial Complex I with 18F-BCPP-EF in the Brains of MPTP-Treated Monkeys.

Published in:

Journal of Nuclear Medicine, 2016, v. 57, n. 6, p. 950, doi. 10.2967/jnumed.115.169615

By:

Hideo Tsukada;
Masakatsu Kanazawa;
Hiroyuki Ohba;
Shingo Nishiyama;
Norihiro Harada;
Takeharu Kakiuchi

Publication type:

Article

Evaluation of 6-11C-Methyl-m-Tyrosine as a PET Probe for Presynaptic Dopaminergic Activity: A Comparison PET Study with β-11C-L-DOPA and 18F-FDOPA in Parkinson Disease Monkeys.

Published in:

Journal of Nuclear Medicine, 2016, v. 57, n. 2, p. 303, doi. 10.2967/jnumed.115.161802

By:

Masakatsu Kanazawa;
Hiroyuki Ohba;
Norihiro Harada;
Takeharu Kakiuchi;
Shin-ichi Muramatsu;
Hideo Tsukada

Publication type:

Article

Validation of Reference Tissue Model of PET Ligand [11C](+)3-MPB for the Muscarinic Cholinergic Receptor in the Living Brain of Conscious Monkey.

Published in:

Synapse, 2011, v. 65, n. 6, p. 548, doi. 10.1002/syn.20881

By:

YAMAMOTO, SHIGEYUKI;
OHBA, HIROYUKI;
NISHIYAMA, SHINGO;
TAKAHASHI, KAZUHIRO;
TSUKADA, HIDEO

Publication type:

Article

Differential effects of stress on [11C]raclopride and [11C]MNPA binding to striatal D2/D3 dopamine receptors: A PET study in conscious monkeys.

Published in:

Synapse, 2011, v. 65, n. 1, p. 84, doi. 10.1002/syn.20845

By:

Tsukada, Hideo;
Ohba, Hiroyuki;
Nishiyama, Shingo;
Kakiuchi, Takeharu

Publication type:

Article

Ketamine/xylazine anesthesia alters [11C]MNPA binding to dopamine D2 receptors and response to methamphetamine challenge in monkey brain.

Published in:

Synapse, 2009, v. 63, n. 6, p. 534, doi. 10.1002/syn.20632

By:

Ohba, Hiroyuki;
Harada, Norihiro;
Nishiyama, Shingo;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

Potential of [18F]β-CFT-FE (2β-carbomethoxy-3β-(4-fluorophenyl)-8-(2-[18F]fluoroethyl)nortropane) as a dopamine transporter ligand: A PET study in the conscious monkey brain.

Published in:

Synapse, 2004, v. 54, n. 1, p. 37, doi. 10.1002/syn.20059

By:

Harada, Norihiro;
Ohba, Hiroyuki;
Fukumoto, Dai;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

Effects of acute acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: Functional imaging of the conscious monkey brain using animal PET in combination with microdialysis.

Published in:

Synapse, 2004, v. 52, n. 1, p. 1, doi. 10.1002/syn.10310

By:

Hideo Tsukada;
Shingo Nishiyama;
Dai Fukumoto;
Hiroyuki Ohba;
Kengo Sato;
Takeharu Kakiuchi

Publication type:

Article

Age differences in phosphodiesterase type-IV and its functional response to dopamine D1 receptor modulation in the living brain: A PET study in conscious monkeys.

Published in:

Synapse, 2002, v. 44, n. 3, p. 139, doi. 10.1002/syn.10067

By:

Harada, Norihiro;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Sato, Kengo;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

Facilitation of dopaminergic neural transmission does not affect [11C]SCH23390 binding to the striatal D1 dopamine receptors, but the facilitation enhances phosphodiesterase type-IV activity through D1 receptors: PET studies in the conscious monkey brain

Published in:

Synapse, 2001, v. 42, n. 4, p. 258, doi. 10.1002/syn.10013

By:

Tsukada, Hideo;
Harada, Norihiro;
Ohba, Hiroyuki;
Nishiyama, Shingo;
Kakiuchi, Takeharu

Publication type:

Article

Ketamine alters the availability of striatal dopamine transporter as measured by [11C]β-CFT and [11C]β-CIT-FE in the monkey brain.

Published in:

Synapse, 2001, v. 42, n. 4, p. 273, doi. 10.1002/syn.10012

By:

Tsukada, Hideo;
Nishiyama, Shingo;
Kakiuchi, Takeharu;
Ohba, Hiroyuki;
Sato, Kengo;
Harada, Norihiro

Publication type:

Article

Effects of aging on 5-HT1A receptors and their functional response to 5-HT1a agonist in the living brain: PET study with [ carbonyl-11C]WAY-100635 in conscious monkeys.

Published in:

Synapse, 2001, v. 42, n. 4, p. 242, doi. 10.1002/syn.10011

By:

Tsukada, Hideo;
Kakiuchi, Takeharu;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Harada, Norihiro

Publication type:

Article

Cholinergic neuronal modulations affect striatal dopamine transporter activity: PET studies in the conscious monkey brain.

Published in:

Synapse, 2001, v. 42, n. 3, p. 193, doi. 10.1002/syn.10003

By:

Tsukada, Hideo;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Sato, Kengo;
Harada, Norihiro;
Kakiuchi, Takeharu

Publication type:

Article

Age differences in muscarinic cholinergic receptors assayed with (+) N-[11C]methyl-3-piperidyl benzilate in the brains of conscious monkeys.

Published in:

Synapse, 2001, v. 41, n. 3, p. 248, doi. 10.1002/syn.1082

By:

Tsukada, Hideo;
Kakiuchi, Takeharu;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Sato, Kengo;
Harada, Norihiro;
Takahashi, Kazuhiro

Publication type:

Article

Evaluation of PET ligands (+) N-[11C]ethyl-3-piperidyl benzilate and (+) N-[11C]propyl-3-piperidyl benzilate for muscarinic cholinergic receptors: A PET study with microdialysis in comparison with (+) N-[11C]methyl-3-piperidyl benzilate in the conscious monkey brain

Published in:

Synapse, 2001, v. 40, n. 3, p. 159, doi. 10.1002/syn.1038

By:

Nishiyama, Shingo;
Tsukada, Hideo;
Sato, Kengo;
Kakiuchi, Takeharu;
Ohba, Hiroyuki;
Harada, Norihiro;
Takahashi, Kazuhiro

Publication type:

Article

Evaluation of novel PET ligands (+) N-[11C]methyl-3-piperidyl benzilate ([11C](+)3-MPB) and its stereoisomer [11C](-)3-MPB for muscarinic cholinergic receptors in the conscious monkey brain: A PET study in comparison with [11C]4-MPB

Published in:

Synapse, 2001, v. 39, n. 2, p. 182, doi. 10.1002/1098-2396(200102)39:2<182::AID-SYN10>3.0.CO;2-Q

By:

Tsukada, Hideo;
Takahashi, Kazuhiro;
Miura, Shuichi;
Nishiyama, Shingo;
Kakiuchi, Takeharu;
Ohba, Hiroyuki;
Sato, Kengo;
Hatazawa, Jun;
Okudera, Toshio

Publication type:

Article

Ketamine decreased striatal [11C]raclopride binding with no alterations in static dopamine concentrations in the striatal extracellular fluid in the monkey brain: Multiparametric PET studies combined with microdialysis analysis.

Published in:

Synapse, 2000, v. 37, n. 2, p. 95, doi. 10.1002/1098-2396(200008)37:2<95::AID-SYN3>3.0.CO;2-H

By:

Tsukada, Hideo;
Harada, Norihiro;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Sato, Kengo;
Fukumoto, Dai;
Kakiuchi, Takeharu

Publication type:

Article

Imaging mitochondrial complex I activation during a vibrotactile stimulation: A PET study using [ 18 F]BCPP-EF in the conscious monkey brain.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2020, v. 40, n. 12, p. 2521, doi. 10.1177/0271678X19900034

By:

Fang, Jingwan;
Ohba, Hiroyuki;
Hashimoto, Fumio;
Tsukada, Hideo;
Chen, Feiyan;
Liu, Huafeng

Publication type:

Article

PET imaging of ischemia-induced impairment of mitochondrial complex I function in monkey brain.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 4, p. 708, doi. 10.1038/jcbfm.2014.5

By:

Tsukada, Hideo;
Ohba, Hiroyuki;
Nishiyama, Shingo;
Kanazawa, Masakatsu;
Kakiuchi, Takeharu;
Harada, Norihiro

Publication type:

Article

Feedback-controlled bolus plus infusion (FC-B/I) method for quantitative drug assessment in living brain with PET.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 1, p. 85, doi. 10.1038/jcbfm.2012.134

By:

Ohba, Hiroyuki;
Harada, Norihiro;
Nishiyama, Shingo;
Kakiuchi, Takeharu;
Kimura, Yuichi;
Tsukada, Hideo

Publication type:

Article

Regulation of homologous integration in yeast by the DNA repair proteins Ku70 and RecQ.

Published in:

Molecular Genetics & Genomics, 2005, v. 273, n. 2, p. 167, doi. 10.1007/s00438-005-1108-y

By:

Yoshimasa Yamana;
Toshinari Maeda;
Hiroyuki Ohba;
Takehiko Usui;
Hiroaki I. Ogawa;
Kohji Kusano

Publication type:

Article

Head-to-head comparison of (R)-[11C]verapamil and [18F]MC225 in non-human primates, tracers for measuring P-glycoprotein function.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 13, p. 4307, doi. 10.1007/s00259-021-05411-2

By:

García-Varela, Lara;
Vállez García, David;
Aguiar, Pablo;
Kakiuchi, Takeharu;
Ohba, Hiroyuki;
Harada, Norihiro;
Nishiyama, Shingo;
Tago, Tetsuro;
Elsinga, Philip H.;
Tsukada, Hideo;
Colabufo, Nicola A.;
Dierckx, Rudi A. J. O.;
van Waarde, Aren;
Toyohara, Jun;
Boellaard, Ronald;
Luurtsema, Gert

Publication type:

Article

Comparing amyloid-β deposition, neuroinflammation, glucose metabolism, and mitochondrial complex I activity in brain: a PET study in aged monkeys.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2014, v. 41, n. 11, p. 2127, doi. 10.1007/s00259-014-2821-8

By:

Tsukada, Hideo;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Kanazawa, Masakatsu;
Kakiuchi, Takeharu;
Harada, Norihiro

Publication type:

Article

Evaluation of F-BCPP-EF for mitochondrial complex 1 imaging in the brain of conscious monkeys using PET.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2014, v. 41, n. 4, p. 755, doi. 10.1007/s00259-013-2628-z

By:

Tsukada, Hideo;
Ohba, Hiroyuki;
Kanazawa, Masakatsu;
Kakiuchi, Takeharu;
Harada, Norihiro

Publication type:

Article

Expression and Function of Sox21 During Mouse Cochlea Development.

Published in:

Neurochemical Research, 2011, v. 36, n. 7, p. 1261, doi. 10.1007/s11064-011-0416-3

By:

Hosoya, Makoto;
Fujioka, Masato;
Matsuda, Satoru;
Ohba, Hiroyuki;
Shibata, Shinsuke;
Nakagawa, Fumiko;
Watabe, Takahisa;
Wakabayashi, Ken-ichiro;
Saga, Yumiko;
Ogawa, Kaoru;
Okano, Hirotaka;
Okano, Hideyuki

Publication type:

Article

Subanesthetic Doses of Ketamine Transiently Decrease Serotonin Transporter Activity: A PET Study in Conscious Monkeys.

Published in:

Neuropsychopharmacology, 2013, v. 38, n. 13, p. 2666, doi. 10.1038/npp.2013.176

By:

Yamamoto, Shigeyuki;
Ohba, Hiroyuki;
Nishiyama, Shingo;
Harada, Norihiro;
Kakiuchi, Takeharu;
Tsukada, Hideo;
Domino, Edward F

Publication type:

Article

Muscarinic Receptor Occupancy and Cognitive Impairment: A PET Study with [11C](+)3-MPB and Scopolamine in Conscious Monkeys.

Published in:

Neuropsychopharmacology, 2011, v. 36, n. 7, p. 1455, doi. 10.1038/npp.2011.31

By:

Yamamoto, Shigeyuki;
Nishiyama, Shingo;
Kawamata, Masahiro;
Ohba, Hiroyuki;
Wakuda, Tomoyasu;
Takei, Nori;
Tsukada, Hideo;
Domino, Edward F.

Publication type:

Article

Effect of Oxygen Affinity of Liposome-Encapsulated Hemoglobin on Cerebral Ischemia and Reperfusion as Detected by Positron Emission Tomography in Nonhuman Primates.

Published in:

Artificial Organs, 2017, v. 41, n. 4, p. 336, doi. 10.1111/aor.12905

By:

Kawaguchi, Akira T.;
Yamano, Mariko;
Haida, Munetaka;
Ohba, Hiroyuki;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

Liposome-Encapsulated Hemoglobin Ameliorates Ischemic Stroke in Nonhuman Primates: Longitudinal Observation.

Published in:

Artificial Organs, 2013, v. 37, n. 10, p. 904, doi. 10.1111/aor.12091

By:

Kawaguchi, Akira T.;
Haida, Munetaka;
Ohba, Hiroyuki;
Yamano, Mariko;
Fukumoto, Dai;
Tsukada, Hideo

Publication type:

Article

Brain p3‐Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β‐peptide.

Published in:

EMBO Molecular Medicine, 2023, v. 15, n. 5, p. 1, doi. 10.15252/emmm.202217052

By:

Hata, Saori;
Saito, Haruka;
Kakiuchi, Takeharu;
Fukumoto, Dai;
Yamamoto, Shigeyuki;
Kasuga, Kensaku;
Kimura, Ayano;
Moteki, Koichi;
Abe, Ruriko;
Adachi, Shungo;
Kinoshita, Shoich;
Yoshizawa‐Kumagaye, Kumiko;
Nishio, Hideki;
Saito, Takashi;
Saido, Takaomi C;
Yamamoto, Tohru;
Nishimura, Masaki;
Taru, Hidenori;
Sobu, Yuriko;
Ohba, Hiroyuki

Publication type:

Article

Comparing α7 nicotinic acetylcholine receptor binding, amyloid-β deposition, and mitochondria complex-I function in living brain: A PET study in aged monkeys.

Published in:

Synapse, 2015, v. 69, n. 10, p. 475, doi. 10.1002/syn.21842

By:

Nishiyama, Shingo;
Ohba, Hiroyuki;
Kanazawa, Masakatsu;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

Development of novel PET probe [11C]( R, R)HAPT and its stereoisomer [11C]( S, S)HAPT for vesicular acetylcholine transporter imaging: A PET study in conscious monkey.

Published in:

Synapse, 2014, v. 68, n. 7, p. 283, doi. 10.1002/syn.21743

By:

Nishiyama, Shingo;
Ohba, Hiroyuki;
Kobashi, Tatsuhiro;
Nakamasu, Yumi;
Nakao, Hidekazu;
Ogata, Tokutaro;
Kitashoji, Takeru;
Tsukada, Hideo

Publication type:

Article

Application of feedback-controlled bolus plus infusion (FC-B/I) method for quantitative PET imaging of dopamine transporters with [18F]β-CFT-FE in conscious monkey brain.

Published in:

Synapse, 2013, v. 67, n. 1, p. 42, doi. 10.1002/syn.21614

By:

Harada, Norihiro;
Ohba, Hiroyuki;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

In vivo alterations of mitochondrial activity and amyloidosis in early-stage senescence-accelerated mice: a positron emission tomography study.

Published in:

2021

By:

Yamagishi, Satoru;
Iga, Yurika;
Ikegaya, Shunsuke;
Kakiuchi, Takeharu;
Ohba, Hiroyuki;
Nishiyama, Shingo;
Fukomoto, Daisuke;
Kanazawa, Masakatsu;
Harada, Norihiro;
Tsukada, Hideo;
Sato, Kohji;
Ouchi, Yasuomi

Publication type:

journal article

Early distribution of18 F‐labeled AAV9 vectors in the cerebrospinal fluid after intracerebroventricular or intracisternal magna infusion in non‐human primates.

Published in:

Journal of Gene Medicine, 2023, v. 25, n. 1, p. 1, doi. 10.1002/jgm.3457

By:

Kumagai, Shinichi;
Nakajima, Takeshi;
Shimazaki, Kuniko;
Kakiuchi, Takeharu;
Harada, Norihiro;
Ohba, Hiroyuki;
Onuki, Yoshiyuki;
Takino, Naomi;
Ito, Mika;
Sato, Makoto;
Nakamura, Sachie;
Osaka, Hitoshi;
Yamagata, Takanori;
Kawai, Kensuke;
Muramatsu, Shin‐ichi

Publication type:

Article

Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity.

Published in:

EJNMMI Research, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13550-021-00841-3

By:

Hosoi, Rie;
Fujii, Yuka;
Hiroyuki, Ohba;
Shukuri, Miho;
Nishiyama, Shingo;
Kanazawa, Masakatsu;
Todoroki, Kenichiro;
Arano, Yasushi;
Sakai, Toshihiro;
Tsukada, Hideo;
Inoue, Osamu

Publication type:

Article

Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography.

Published in:

EJNMMI Research, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13550-020-00702-5

By:

Toyohara, Jun;
Harada, Norihiro;
Kakiuchi, Takeharu;
Ohba, Hiroyuki;
Kanazawa, Masakatsu;
Tago, Tetsuro;
Sakata, Muneyuki;
Ishiwata, Kiichi

Publication type:

Article

Sensitive and early detection of mitochondrial dysfunction in the liver of NASH model mice by PET imaging with 18F-BCPP-BF.

Published in:

EJNMMI Research, 2018, v. 8, n. 1, p. 1, doi. 10.1186/s13550-018-0420-6

By:

Sakai, Toshihiro;
Inoue, Osamu;
Ohba, Hiroyuki;
Nishiyama, Shingo;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

Effects of acetaminophen on mitochondrial complex I activity in the rat liver and kidney: a PET study with F-BCPP-BF.

Published in:

EJNMMI Research, 2016, v. 6, n. 1, p. 1, doi. 10.1186/s13550-016-0241-4

By:

Ohba, Hiroyuki;
Kanazawa, Masakatsu;
Kakiuchi, Takeharu;
Tsukada, Hideo

Publication type:

Article

[11C]CHIBA-1001 as a Novel PET Ligand for α7 Nicotinic Receptors in the Brain: A PET Study in Conscious Monkeys.

Published in:

PLoS ONE, 2008, v. 3, n. 9, p. 1, doi. 10.1371/journal.pone.0003231

By:

Hashimoto, Kenji;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Matsuo, Masaaki;
Kobashi, Tatsuhiko;
Takahagi, Makoto;
Iyo, Masaomi;
Kitashoji, Takeru;
Tsukada, Hideo

Publication type:

Article

User Fee in U.S. Public Libraries: The History and Provision in State Library Laws.

Published in:

Library & Information Science (03734447), 2024, n. 92, p. 1, doi. 10.46895/lis.92.1

By:

Hiroyuki OHBA

Publication type:

Article

Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study.

Published in:

2019

By:

Yamagishi, Satoru;
Iga, Yurika;
Nakamura, Masato;
Takizawa, Chika;
Fukumoto, Dai;
Kakiuchi, Takeharu;
Nishiyama, Shingo;
Ohba, Hiroyuki;
Tsukada, Hideo;
Sato, Kohji;
Ouchi, Yasuomi

Publication type:

journal article

Animal PET scanner with a large field of view is suitable for high-throughput scanning of rodents.

Published in:

Annals of Nuclear Medicine, 2024, v. 38, n. 7, p. 544, doi. 10.1007/s12149-024-01937-1

By:

Tomonari, Yuki;
Onishi, Yuya;
Hashimoto, Fumio;
Ote, Kibo;
Okamoto, Takashi;
Ohba, Hiroyuki

Publication type:

Article

Reduction of dopamine D receptor binding in the striatum after a single administration of esketamine, but not R-ketamine: a PET study in conscious monkeys.

Published in:

European Archives of Psychiatry & Clinical Neuroscience, 2017, v. 267, n. 2, p. 173, doi. 10.1007/s00406-016-0692-7

By:

Hashimoto, Kenji;
Kakiuchi, Takeharu;
Ohba, Hiroyuki;
Nishiyama, Shingo;
Tsukada, Hideo

Publication type:

Article