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Effects of Nitric Oxide and Reactive Oxygen Species on HIF-1α Stabilization Following Clostridium Difficile Toxin Exposure of the Caco-2 Epithelial Cell Line.
Published in:
Cellular Physiology & Biochemistry (Karger AG), 2013, v. 32, n. 2, p. 417, doi. 10.1159/000354448
By:
- Lee, Joshua Y.;
- Hirota, Simon a.;
- Glover, Louise E.;
- armstrong, Glen D.;
- Beck, Paul L.;
- MacDonald, Justin a.
Publication type:
Article
Vascular relaxation response to hydrogen peroxide is impaired in hypertension.
Published in:
British Journal of Pharmacology, 2004, v. 142, n. 1, p. 143, doi. 10.1038/sj.bjp.0705727
By:
- Yu-jing Gao;
- Yongde Zhang;
- Hirota, Simon;
- Janssen, Luke J.;
- Lee, Robert M. K. W.
Publication type:
Article
Mechanisms of hydrogen-peroxide-induced biphasic response in rat mesenteric artery.
Published in:
British Journal of Pharmacology, 2003, v. 138, n. 6, p. 1085, doi. 10.1038/sj.bjp.0705147
By:
- Yu-Jing Gao;
- Hirota, Simon;
- Da-Wei Zhang;
- Janssen, Luke J.;
- Lee, Robert M.K.W.
Publication type:
Article
Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis.
Published in:
Nature Medicine, 2012, v. 18, n. 4, p. 600, doi. 10.1038/nm.2679
By:
- Gulbransen, Brian D;
- Bashashati, Mohammad;
- Hirota, Simon A;
- Gui, Xianyong;
- Roberts, Jane A;
- MacDonald, Justin A;
- Muruve, Daniel A;
- McKay, Derek M;
- Beck, Paul L;
- Mawe, Gary M;
- Thompson, Roger J;
- Sharkey, Keith A
Publication type:
Article
Giardia duodenalis Infection Reduces Granulocyte Infiltration in an In Vivo Model of Bacterial Toxin-Induced Colitis and Attenuates Inflammation in Human Intestinal Tissue.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109087
By:
- Cotton, James A.;
- Motta, Jean-Paul;
- Schenck, L. Patrick;
- Hirota, Simon A.;
- Beck, Paul L.;
- Buret, Andre G.
Publication type:
Article
The P2Y6 Receptor Mediates Clostridium difficile Toxin-Induced CXCL8/IL-8 Production and Intestinal Epithelial Barrier Dysfunction.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081491
By:
- Hansen, Ashleigh;
- Alston, Laurie;
- Tulk, Sarah E.;
- Schenck, L. Patrick;
- Grassie, Michael E.;
- Alhassan, Basmah F.;
- Veermalla, Arun Teja;
- Al-Bashir, Samir;
- Gendron, Fernand-Pierre;
- Altier, Christophe;
- MacDonald, Justin A.;
- Beck, Paul L.;
- Hirota, Simon A.
Publication type:
Article
Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice.
Published in:
Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/5637685
By:
- Hirota, Simon A.;
- Ueno, Aito;
- Tulk, Sarah E.;
- Becker, Helen M.;
- Schenck, L. Patrick;
- Potentier, Mireille S.;
- Li, Yan;
- Ghosh, Subrata;
- Muruve, Daniel A.;
- MacDonald, Justin A.;
- Beck, Paul L.
Publication type:
Article
E-Ring Isoprostanes Stimulate a Cl- Conductance in Airway Epithelium via Prostaglandin E2-Selective Prostanoid Receptors.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2008, v. 38, n. 1, p. 88, doi. 10.1165/rcmb.2007-0117OC
By:
- Seto, Victoria;
- Hirota, Christina;
- Hirota, Simon;
- Janssen, Luke J.
Publication type:
Article
NR4A1 modulates intestinal smooth muscle cell phenotype and dampens inflammation‐associated intestinal remodeling.
Published in:
FASEB Journal, 2022, v. 36, n. 11, p. 1, doi. 10.1096/fj.202101817RR
By:
- Szczepanski, Holly E.;
- Flannigan, Kyle L.;
- Mainoli, Barbara;
- Alston, Laurie;
- Baruta, Grace M.;
- Lee, Joshua W.;
- Venu, Vivek Krishna Pulakazhi;
- Shearer, Jane;
- Dufour, Antoine;
- Hirota, Simon A.
Publication type:
Article
The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins.
Published in:
FASEB Journal, 2020, v. 34, n. 2, p. 2198, doi. 10.1096/fj.201902083RR
By:
- Erickson, Sarah L.;
- Alston, Laurie;
- Nieves, Kristoff;
- Chang, Thomas K. H.;
- Mani, Sridhar;
- Flannigan, Kyle L.;
- Hirota, Simon A.
Publication type:
Article
Investigating the effect of antibiotics on gut microbiota components and subsequent Clostridium difficile infection (LB516).
Published in:
FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.lb516
By:
- Schenck, Louis Patrick;
- Hirota, Simon;
- Armstrong, Glen;
- MacDonald, Justin;
- Beck, Paul
Publication type:
Article
Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior.
Published in:
2022
By:
- Cluny, Nina L.;
- Nyuyki, Kewir D.;
- Almishri, Wagdi;
- Griffin, Lateece;
- Lee, Benjamin H.;
- Hirota, Simon A.;
- Pittman, Quentin J.;
- Swain, Mark G.;
- Sharkey, Keith A.
Publication type:
journal article
Heat shock protein-27 and sex-selective regulation of muscarinic and proteinase-activated receptor 2-mediated vasodilatation: differential sensitivity to endothelial NOS inhibition.
Published in:
2018
By:
- Pulakazhi Venu, Vivek Krishna;
- Saifeddine, Mahmoud;
- Mihara, Koichiro;
- El‐Daly, Mahmoud;
- Belke, Darrell;
- Dean, Jonathan L E;
- O'Brien, Edward R;
- Hirota, Simon A;
- Hollenberg, Morley D;
- El-Daly, Mahmoud
Publication type:
journal article
Constitutive androstane receptor regulates the intestinal mucosal response to injury.
Published in:
2017
By:
- Hudson, Grace M;
- Flannigan, Kyle L;
- Erickson, Sarah L;
- Vicentini, Fernando A;
- Zamponi, Alexandra;
- Hirota, Christina L;
- Alston, Laurie;
- Altier, Christophe;
- Ghosh, Subrata;
- Rioux, Kevin P;
- Mani, Sridhar;
- Chang, Thomas K;
- Hirota, Simon A
Publication type:
journal article
Airway smooth muscle excitation-contraction coupling and airway hyperresponsiveness.
Published in:
Canadian Journal of Physiology & Pharmacology, 2005, v. 83, n. 8/9, p. 725, doi. 10.1139/Y05-070
By:
- Hirota, Simon;
- Helli, Peter B.;
- Catalli, Adriana;
- Chew, Allyson;
- Janssen, Luke J.
Publication type:
Article
The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.
Published in:
Experimental Physiology, 2013, v. 98, n. 2, p. 462, doi. 10.1113/expphysiol.2012.068338
By:
- Bracey, Nathan A.;
- Beck, Paul L.;
- Muruve, Daniel A.;
- Hirota, Simon A.;
- Guo, Jiqing;
- Jabagi, Habib;
- Wright Jr, James R.;
- MacDonald, Justin A.;
- Lees‐Miller, James P.;
- Roach, Daniel;
- Semeniuk, Lisa M.;
- Duff, Henry J.
Publication type:
Article
A Trypsin-Sensitive Proteoglycan from the Tapeworm Hymenolepis diminuta Inhibits Murine Neutrophil Chemotaxis in vitro by Suppressing p38 MAP Kinase Activation.
Published in:
Journal of Innate Immunity, 2019, v. 11, n. 2, p. 136, doi. 10.1159/000492303
By:
- Graves, Nicholas;
- Venu, Vivek P.;
- Yipp, Bryan G.;
- Petri, Björn;
- Hirota, Simon;
- Gilleard, John;
- McKay, Derek M.;
- Lopes, Fernando
Publication type:
Article
Gut microbiota profiles and fecal beta‐glucuronidase activity in kidney transplant recipients with and without post‐transplant diarrhea.
Published in:
Clinical Transplantation, 2021, v. 35, n. 5, p. 1, doi. 10.1111/ctr.14260
By:
- Zhang, Lisa T.;
- Westblade, Lars F.;
- Iqbal, Fatima;
- Taylor, Michael R.;
- Chung, Alice;
- Satlin, Michael J.;
- Magruder, Matthew;
- Edusei, Emmanuel;
- Albakry, Shady;
- Botticelli, Brittany;
- Robertson, Amy;
- Alston, Tricia;
- Dadhania, Darshana M.;
- Lubetzky, Michelle;
- Hirota, Simon A.;
- Greenway, Steven C.;
- Lee, John R.
Publication type:
Article
Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia.
Published in:
Microbiome, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40168-021-01165-z
By:
- Vicentini, Fernando A.;
- Keenan, Catherine M.;
- Wallace, Laurie E.;
- Woods, Crystal;
- Cavin, Jean-Baptiste;
- Flockton, Amanda R.;
- Macklin, Wendy B.;
- Belkind-Gerson, Jaime;
- Hirota, Simon A.;
- Sharkey, Keith A.
Publication type:
Article

Found: 19

Effects of Nitric Oxide and Reactive Oxygen Species on HIF-1α Stabilization Following Clostridium Difficile Toxin Exposure of the Caco-2 Epithelial Cell Line.

Vascular relaxation response to hydrogen peroxide is impaired in hypertension.

Mechanisms of hydrogen-peroxide-induced biphasic response in rat mesenteric artery.

Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis.

Giardia duodenalis Infection Reduces Granulocyte Infiltration in an In Vivo Model of Bacterial Toxin-Induced Colitis and Attenuates Inflammation in Human Intestinal Tissue.

The P2Y<sub>6</sub> Receptor Mediates <i>Clostridium difficile</i> Toxin-Induced CXCL8/IL-8 Production and Intestinal Epithelial Barrier Dysfunction.

Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice.

E-Ring Isoprostanes Stimulate a Cl<sup>-</sup> Conductance in Airway Epithelium via Prostaglandin E<sub>2</sub>-Selective Prostanoid Receptors.

NR4A1 modulates intestinal smooth muscle cell phenotype and dampens inflammation‐associated intestinal remodeling.

The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins.

Investigating the effect of antibiotics on gut microbiota components and subsequent Clostridium difficile infection (LB516).

Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior.

Heat shock protein-27 and sex-selective regulation of muscarinic and proteinase-activated receptor 2-mediated vasodilatation: differential sensitivity to endothelial NOS inhibition.

Constitutive androstane receptor regulates the intestinal mucosal response to injury.

Airway smooth muscle excitation-contraction coupling and airway hyperresponsiveness.

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.

A Trypsin-Sensitive Proteoglycan from the Tapeworm Hymenolepis diminuta Inhibits Murine Neutrophil Chemotaxis in vitro by Suppressing p38 MAP Kinase Activation.

Gut microbiota profiles and fecal beta‐glucuronidase activity in kidney transplant recipients with and without post‐transplant diarrhea.

Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia.