Works by Hiroshi Kasai

Results: 72

The Association between Oxidative Balance Score and Urinary Levels of 8-Hydroxydeoxyguanosine among Japanese Adults.

Published in:

Nutrients, 2023, v. 15, n. 21, p. 4533, doi. 10.3390/nu15214533

By:

Nanri, Hinako;
Hara, Megumi;
Nishida, Yuichiro;
Shimanoe, Chisato;
Li, Yun-Shan;
Kasai, Hiroshi;
Kawai, Kazuaki;
Higaki, Yasuki;
Tanaka, Keitaro

Publication type:

Article

Magnetic nanoparticles of Fe3O4 enhance docetaxel-induced prostate cancer cell death.

Published in:

International Journal of Nanomedicine, 2013, v. 8, p. 3151, doi. 10.2147/IJN.S40766

By:

Sato, Akiko;
Itcho, Naoki;
Ishiguro, Hitoshi;
Okamoto, Daiki;
Kobayashi, Naohito;
Kawai, Kazuaki;
Kasai, Hiroshi;
Kurioka, Daisuke;
Uemura, Hiroji;
Kubota, Yoshinobu;
Watanabe, Masatoshi

Publication type:

Article

Leisure-time physical activity and DNA damage among Japanese workers.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0212499

By:

Kawakami, Ryoko;
Kashino, Ikuko;
Kasai, Hiroshi;
Kawai, Kazuaki;
Li, Yun-Shan;
Nanri, Akiko;
Higuchi, Mitsuru;
Mizoue, Tetsuya

Publication type:

Article

Symptoms and molecular characterization of apple dimple fruit viroid isolates from apples in Japan.

Published in:

Journal of General Plant Pathology, 2017, v. 83, n. 4, p. 268, doi. 10.1007/s10327-017-0718-7

By:

Kasai, Hiroshi;
Ito, Tsutae;
Sano, Teruo

Publication type:

Article

Circadian Disruption Accelerates Tumor Growth and Angio/Stromagenesis through a Wnt Signaling Pathway.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015330

By:

Yasuniwa, Yoshihiro;
Izumi, Hiroto;
Wang, Ke-Yong;
Shimajiri, Shohei;
Sasaguri, Yasuyuki;
Kawai, Kazuaki;
Kasai, Hiroshi;
Shimada, Takashi;
Miyake, Koichi;
Kashiwagi, Eiji;
Hirano, Gen;
Kidani, Akihiko;
Akiyama, Masaki;
Bin Han;
Ying Wu;
Ieiri, Ichiro;
Shun Higuchi;
Kohno, Kimitoshi

Publication type:

Article

Psychological mediation of a type of oxidative DNA damage, 8-hydroxydeoxyguanosine, in peripheral blood leukocytes of non-smoking and non-drinking workers.

Published in:

2002

By:

Irie, Masahiro;
Asami, Shinya;
Nagata, Shoji;
Miyata, Masakazu;
Kasai, Hiroshi

Publication type:

journal article

Free radical-mediated acetaldehyde formation by model reactions of dietary components: effects of meat, wine, cooking oil and coffee.

Published in:

Genes & Environment, 2021, v. 43, n. 1, p. 1, doi. 10.1186/s41021-021-00201-6

By:

Kasai, Hiroshi;
Kawai, Kazuaki

Publication type:

Article

Measurement of 8-hydroxyguanine as an oxidative stress biomarker in saliva by HPLC-ECD.

Published in:

Genes & Environment, 2018, v. 40, p. N.PAG, doi. 10.1186/s41021-018-0095-2

By:

Kawai, Kazuaki;
Kasai, Hiroshi;
Li, Yun-Shan;
Kawasaki, Yuya;
Watanabe, Shintaro;
Ohta, Masanori;
Honda, Toru;
Yamato, Hiroshi

Publication type:

Article

What causes human cancer? Approaches from the chemistry of DNA damage.

Published in:

Genes & Environment, 2016, v. 38, p. 1, doi. 10.1186/s41021-016-0046-8

By:

Hiroshi Kasai

Publication type:

Article

Generation and Threshold Level of 8-OHdG as Oxidative DNA Damage Elicited by Low Dose Ionizing Radiation.

Published in:

Genes & Environment, 2013, v. 35, n. 3, p. 88, doi. 10.3123/jemsge.2013.006

By:

Yun-Shan Li;
Ming-Fen Song;
Hiroshi Kasai;
Kazuaki Kawai

Publication type:

Article

Analyses of 8-Methyldeoxyadenosine and 8-Methyldeoxyguanosine as Markers of Free Radical-mediated DNA Methylation in Mouse.

Published in:

Genes & Environment, 2013, v. 35, n. 1, p. 5, doi. 10.3123/jemsge.35.5

By:

Hiroshi Kasai;
Kazuaki Kawai;
Ming-Fen Song;
Yun-Shan Li;
Tomomi Hattori;
Tomonari Matsuda

Publication type:

Article

Intensity-specific effect of physical activity on urinary levels of 8-hydroxydeoxyguanosine in middle-aged Japanese.

Published in:

Cancer Science, 2016, v. 107, n. 11, p. 1653, doi. 10.1111/cas.13070

By:

Hara, Megumi;
Nishida, Yuichiro;
Shimanoe, Chisato;
Otsuka, Yasuko;
Nanri, Hinako;
Yasukata, Jun;
Miyoshi, Nobuyuki;
Yamada, Yosuke;
Horita, Mikako;
Kawai, Kazuaki;
Li, Yun‐Shan;
Kasai, Jun;
Kasai, Hiroshi;
Higaki, Yasuki;
Tanaka, Keitaro

Publication type:

Article

Body iron store as a predictor of oxidative DNA damage in healthy men and women.

Published in:

Cancer Science, 2010, v. 101, n. 2, p. 517, doi. 10.1111/j.1349-7006.2009.01394.x

By:

Hori, Ai;
Mizoue, Tetsuya;
Kasai, Hiroshi;
Kawai, Kazuaki;
Matsushita, Yumi;
Nanri, Akiko;
Sato, Masao;
Ohta, Masanori

Publication type:

Article

Effect of age, smoking and other lifestyle factors on urinary 7-methylguanine and 8-hydroxydeoxyguanosine.

Published in:

Cancer Science, 2009, v. 100, n. 4, p. 715, doi. 10.1111/j.1349-7006.2009.01088.x

By:

Tamae, Kazuyoshi;
Kawai, Kazuaki;
Yamasaki, Sayumi;
Kawanami, Kiyoshi;
Ikeda, Masato;
Takahashi, Ken;
Miyamoto, Toshiaki;
Kato, Noritada;
Kasai, Hiroshi

Publication type:

Article

Body mass index and oxidative DNA damage: A longitudinal study.

Published in:

Cancer Science, 2007, v. 98, n. 8, p. 1254, doi. 10.1111/j.1349-7006.2007.00511.x

By:

Mizoue, Tetsuya;
Tokunaga, Shoji;
Kasai, Hiroshi;
Kawai, Kazuaki;
Sato, Masao;
Kubo, Tatsuhiko

Publication type:

Article

Formation of 8-hydroxy-2′-deoxyguanosine in the DNA of cultured human keratinocytes by clinically used doses of narrowband and broadband ultraviolet B and psoralen plus ultraviolet A.

Published in:

Cancer Science, 2006, v. 97, n. 2, p. 99, doi. 10.1111/j.1349-7006.2006.00151.x

By:

Orimo, Hiroshi;
Tokura, Yoshiki;
Hino, Ryosuke;
Kasai, Hiroshi

Publication type:

Article

Occupational and lifestyle factors and urinary 8-hydroxydeoxyguanosine.

Published in:

Cancer Science, 2005, v. 96, n. 9, p. 600, doi. 10.1111/j.1349-7006.2005.00083.x

By:

Irie, Masahiro;
Tamae, Kazuyoshi;
Iwamoto-Tanaka, Naoko;
Kasai, Hiroshi

Publication type:

Article

Analysis of 8-hydroxydeoxyguanosine 5′-monophosphate (8-OH-dGMP) as a reliable marker of cellular oxidative DNA damage after γ-irradiation.

Published in:

Environmental & Molecular Mutagenesis, 2003, v. 41, n. 5, p. 332, doi. 10.1002/em.10165

By:

Mei, Nan;
Tamae, Kazuyoshi;
Kunugita, Naoki;
Hirano, Takeshi;
Kasai, Hiroshi

Publication type:

Article

Prospective study of urinary excretion of 7-methylguanine and the risk of lung cancer: Effect modification by mu class glutathione- S-transferases.

Published in:

International Journal of Cancer, 2007, v. 121, n. 7, p. 1579, doi. 10.1002/ijc.22863

By:

Loft, Steffen;
Svoboda, Peter;
Kasai, Hiroshi;
Tjønneland, Anne;
Møller, Peter;
Sørensen, Mette;
Overvad, Kim;
Autrup, Herman;
Raaschou-Nielsen, Ole

Publication type:

Article

ATL>8-Chloro-dGTP, a hypochlorous acid-modified nucleotide, is hydrolyzed by hMTH1, the human MutT homolog.

Published in:

FEBS Letters, 2002, v. 512, n. 1-3, p. 149, doi. 10.1016/S0014-5793(02)02240-8

By:

Fujikawa, Katsuyoshi;
Yakushiji, Hiroyuki;
Nakabeppu, Yusaku;
Suzuki, Toshinori;
Masuda, Mitsuharu;
Ohshima, Hiroshi;
Kasai, Hiroshi

Publication type:

Article

Relations between clusters of oxidatively damaged nucleotides and active or open nucleosomes in the rat Nth 1 gene.

Published in:

Oncogene, 2002, v. 21, n. 11, p. 1649, doi. 10.1038/sj.onc.1205237

By:

Nomoto, Minoru;
Yamaguchi, Raizo;
Kohno, Kimitoshi;
Kasai, Hiroshi

Publication type:

Article

Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA.

Published in:

Oncogene, 1998, v. 16, n. 25, p. 3219, doi. 10.1038/sj.onc.1201872

By:

Kohno, Takashi;
Shinmura, Kazuya;
Tosaka, Masahiko;
Tani, Masachika;
Kim, Su-Ryang;
Sugimura, Haruhiko;
Nohmi, Takehiko;
Kasai, Hiroshi;
Yokota, Jun

Publication type:

Article

Free radical-mediated cytosine C-5 methylation triggers epigenetic changes during carcinogenesis.

Published in:

Biomolecular Concepts, 2013, v. 4, n. 3, p. 213, doi. 10.1515/bmc-2012-0052

By:

Kasai, Hiroshi;
Kawai, Kazuaki;
Li, Yun-Shan

Publication type:

Article

Coffee Intake is Associated With Lower Levels of Oxidative DNA Damage and Decreasing Body Iron Storage in Healthy Women.

Published in:

Nutrition & Cancer, 2014, v. 66, n. 6, p. 964, doi. 10.1080/01635581.2014.932398

By:

Hori, Ai;
Kasai, Hiroshi;
Kawai, Kazuaki;
Nanri, Akiko;
Sato, Masao;
Ohta, Masanori;
Mizoue, Tetsuya

Publication type:

Article

Immunohistochemical Detection of 8-Hydroxy-2'-deoxyguanosine in Paraffin-Embedded Sections of Rat Liver after Carbon Tetrachloride Treatment

Published in:

Toxicologic Pathology, 1998, v. 26, n. 2, p. 247, doi. 10.1177/019262339802600209

By:

Takahashi, Satoru;
Hirose, Masao;
Tamano, Seiko;
Ozaki, Masakazu;
Orita, Shin-ichiro;
Ito, Takayasu;
Takeuchi, Masao;
Ochi, Hirotomo;
Fukada, Shoko;
Kasai, Hiroshi;
Shirai, Tomoyuki

Publication type:

Article

Lower serum levels of total cholesterol are associated with higher urinary levels of 8-hydroxydeoxyguanosine.

Published in:

Nutrition & Metabolism, 2013, v. 10, n. 1, p. 59, doi. 10.1186/1743-7075-10-59

By:

Hiroyuki Kikuchi;
Akiko Nanri;
Ai Hori;
Masao Sato;
Kazuaki Kawai;
Hiroshi Kasai;
Tetsuya Mizoue

Publication type:

Article

Formation of the toxic furan metabolite 2-butene-1,4-dial through hemin-induced degradation of 2,4-alkadienals in fried foods.

Published in:

Genes & Environment, 2025, v. 47, n. 1, p. 1, doi. 10.1186/s41021-025-00330-2

By:

Kasai, Hiroshi;
Kawai, Kazuaki;
Fujisawa, Koichi

Publication type:

Article

Formation of the mutagenic DNA lesion 1,N2-ethenoguanine induced by heated cooking oil and identification of causative agents.

Published in:

Genes & Environment, 2023, v. 45, n. 1, p. 1, doi. 10.1186/s41021-023-00284-3

By:

Kasai, Hiroshi;
Kawai, Kazuaki

Publication type:

Article

UVA1 Genotoxicity Is Mediated Not by Oxidative Damage but by Cyclobutane Pyrimidine Dimers in Normal Mouse Skin.

Published in:

Journal of Investigative Dermatology, 2008, v. 128, n. 9, p. 2289, doi. 10.1038/jid.2008.61

By:

Ikehata, Hironobu;
Kawai, Kazuaki;
Komura, Jun-ichiro;
Sakatsume, Ko;
Wang, Liangcheng;
Imai, Masaru;
Higashi, Shoichi;
Nikaido, Osamu;
Yamamoto, Kazuo;
Hieda, Kotaro;
Watanabe, Masakatsu;
Kasai, Hiroshi;
Ono, Tetsuya

Publication type:

Article

Comparative Study of Prostaglandin I2 and Prostaglandin E2 on Hemodynamics in Pregnant Dogs.

Published in:

Journal of Obstetrics & Gynaecology Research, 1983, v. 9, n. 3, p. 335, doi. 10.1111/j.1447-0756.1983.tb00641.x

By:

Murayama, Keisaburo;
Kasai, Hiroshi;
Ouchi, Hiroko

Publication type:

Article

Effect of polymerized toner on rat lung in chronic inhalation study.

Published in:

Inhalation Toxicology, 2009, v. 21, n. 11, p. 898, doi. 10.1080/08958370802641938

By:

Morimoto, Yasuo;
Hirohashi, Masami;
Kasai, Takahiko;
Oyabu, Takako;
Ogami, Akira;
Myojo, Toshihiko;
Murakami, Masahiro;
Nishi, Ken-ichiro;
Kadoya, Chikara;
Todoroki, Motoi;
Yamamoto, Makoto;
Kawai, Kazuaki;
Kasai, Hiroshi;
Tanaka, Isamu

Publication type:

Article

Negative Effect of Long-Term Inhalation of Toner on Formation of 8-Hydroxydeoxyguanosine in DNA in the Lungs of Rats In Vivo.

Published in:

Inhalation Toxicology, 2005, v. 17, n. 13, p. 749, doi. 10.1080/08958370500224771

By:

Morimoto, Yasuo;
Kim, Heungnam;
Oyabu, Takako;
Hirohashi, Masami;
Nagatomo, Hiroko;
Ogami, Akira;
Yamato, Hiroshi;
Obata, Yasuko;
Kasai, Hiroshi;
Higashi, Toshiaki;
Tanaka, Isamu

Publication type:

Article

Interlaboratory comparison of methodologies for the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine.

Published in:

Biomarkers, 2009, v. 14, n. 2, p. 103, doi. 10.1080/13547500802706012

By:

Cooke, Marcus S.;
Barregard, Lars;
Mistry, Vilas;
Potdar, Neelam;
Rozalski, Rafal;
Gackowski, Daniel;
Siomek, Agnieszka;
Foksinski, Marek;
Svoboda, Peter;
Kasai, Hiroshi;
Konje, Justin C.;
Sallsten, Gerd;
Evans, Mark D.;
Olinski, Ryszard

Publication type:

Article

Distributions and ranges of values of blood and urinary biomarker of inflammation and oxidative stress in the workers engaged in office machine manufactures: evaluation of reference values.

Published in:

Clinical Chemistry & Laboratory Medicine, 2013, v. 51, n. 2, p. 421, doi. 10.1515/cclm-2012-0330

By:

Murase, Tadashi;
Kitamura, Hiroko;
Kochi, Takeshi;
Terunuma, Niina;
Kurosaki, Shizuka;
Hata, Kouichi;
Yanagi, Nobuaki;
Uchino, Bungo;
Kitahara, Kayo;
Morimoto, Yasuo;
Kasai, Hiroshi;
Sasaki, Toshio;
Ogami, Akira;
Higashi, Toshiaki

Publication type:

Article

8-Hydroxyguanine levels and repair capacity during mouse embryonic stem cell differentiation.

Published in:

Free Radical Research, 2011, v. 45, n. 5, p. 527, doi. 10.3109/10715762.2011.555481

By:

Kuboyama, Ayumi;
Tanaka, Shoichi;
Kawai, Kazuaki;
Kasai, Hiroshi;
Morii, Haruki;
Tamae, Kazuyoshi;
Nakashima, Tamiji;
Hirano, Takeshi

Publication type:

Article

Analysis of 8-hydroxydeoxyguanosine among workers exposed to diesel particulate exhaust: Comparison with urinary metabolites and PAH air monitoring.

Published in:

Free Radical Research, 2005, v. 39, n. 9, p. 963, doi. 10.1080/10715760500190115

By:

Harri, Minna;
Svoboda, Peter;
Mori, Toshiaki;
Mutanen, Pertti;
Kasai, Hiroshi;
Savela, Kirsti

Publication type:

Article

Habitual exercise induced resistance to oxidative stress.

Published in:

Free Radical Research, 2005, v. 39, n. 9, p. 905, doi. 10.1080/10715760500183300

By:

Nakatani, Koji;
Komatsu, Masaharu;
Kato, Toyohiro;
Yamanaka, Takao;
Takekura, Hiroaki;
Wagatsuma, Akira;
Aoyama, Kohji;
Baohui Xu;
Hirano, Takeshi;
Kasai, Hiroshi;
Ando, Seiichi;
Takeuchi, Toru

Publication type:

Article

An oxidized nucleotide affects DNA replication through activation of protein kinases in Xenopus egg lysates.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 2, p. 569, doi. 10.1093/nar/30.2.569

By:

Kai, Toshinori;
Matsunaga, Rieko;
Eguchi, Masami;
Kamiya, Hiroyuki;
Kasai, Hiroshi;
Suzuki, Motoshi;
Izuta, Shunji

Publication type:

Article

Arg660Ser mutation in Thermus aquaticus DNA polymerase I suppresses T→C transitions: implication of wobble base pair formation at the nucleotide incorporation step.

Published in:

Nucleic Acids Research, 2001, v. 29, n. 20, p. 4206, doi. 10.1093/nar/29.20.4206

By:

Yoshida, Katsushi;
Tosaka, Aki;
Kamiya, Hiroyuki;
Murate, Takashi;
Kasai, Hiroshi;
Nimura, Yuji;
Ogawa, Masanori;
Yoshida, Shonen;
Suzuki, Motoshi

Publication type:

Article

Thermodynamic stability of base pairs between 2-hydroxyadenine and incoming nucleotides as a determinant of nucleotide incorporation specificity during replication.

Published in:

Nucleic Acids Research, 2001, v. 29, n. 16, p. 3289, doi. 10.1093/nar/29.16.3289

By:

Kawakami, Junji;
Kamiya, Hiroyuki;
Yasuda, Kyohko;
Kasai, Hiroshi;
Sugimoto, Naoki

Publication type:

Article

Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP.

Published in:

Nucleic Acids Research, 2001, v. 29, n. 2, p. 449, doi. 10.1093/nar/29.2.449

By:

Fujikawa, Katsuyoshi;
Kamiya, Hiroyuki;
Yakushiji, Hiroyuki;
Nakabeppu, Yusaku;
Kasai, Hiroshi

Publication type:

Article

2-Hydroxy-dATP is incorporated opposite G by Escherichia coli DNA polymerase III resulting in high mutagenicity.

Published in:

Nucleic Acids Research, 2000, v. 28, n. 7, p. 1640, doi. 10.1093/nar/28.7.1640

By:

Kamiya, Hiroyuki;
Kasai, Hiroshi

Publication type:

Article

Formation of 5-formyl-2′-deoxycytidine from 5-methyl-2′-deoxycytidine in duplex DNA by Fenton-type reactions and γ-irradiation.

Published in:

Nucleic Acids Research, 1999, v. 27, n. 22, p. 4385, doi. 10.1093/nar/27.22.4385

By:

Murata-Kamiya, Naoko;
Kamiya, Hiroyuki;
Karino, Naoko;
Ueno, Yoshihito;
Kaji, Hiroshi;
Matsuda, Akira;
Kasai, Hiroshi

Publication type:

Article

The mutations induced by oxidatively damaged nucleotides, 5‐formyl‐dUTP and 5‐hydroxy‐dCTP,in Escherichia coli.

Published in:

Nucleic Acids Research, 1998, v. 26, n. 20, p. 4582, doi. 10.1093/nar/26.20.4582

By:

Fujikawa, Katsuyoshi;
Kamiya, Hiroyuki;
Kasai, Hiroshi

Publication type:

Article

The (6–4) photoproduct of thymine–thymine induces targeted substitution mutations in mammalian cells.

Published in:

Nucleic Acids Research, 1998, v. 26, n. 11, p. 2611, doi. 10.1093/nar/26.11.2611

By:

Kamiya, Hiroyuki;
Iwai, Shigenori;
Kasai, Hiroshi

Publication type:

Article

Glyoxal, a major product of DNA oxidation, induces mutations at G:C sites on a shuttle vector plasmid replicated in mammalian cells.

Published in:

Nucleic Acids Research, 1997, v. 25, n. 10, p. 1897, doi. 10.1093/nar/25.10.1897

By:

Murata-Kamiya, Naoko;
Kamiya, Hiroyuki;
Kaji, Hiroshi;
Kasai, Hiroshi

Publication type:

Article

Substitution and deletion mutations induced by 2-hydroxyadenine in Escherichia coli: effects of sequence contexts in leading and lagging strands.

Published in:

Nucleic Acids Research, 1997, v. 25, n. 2, p. 304, doi. 10.1093/nar/25.2.304

By:

Kamiya, Hiroyuki;
Kasai, Hiroshi

Publication type:

Article

Increased Levels of 8-Hydroxy-2′-Deoxyguanosine in Drosophila Larval DNA after Irradiation with 364-nm Laser Light but not with X-rays.

Published in:

Photochemistry & Photobiology, 2007, v. 83, n. 3, p. 658, doi. 10.1562/2006-05-30-RA-905

By:

Negishia, Tomoe;
Kawai, Kazuaki;
Arakawa, Ritsuo;
Higashi, Shoichi;
Nakamura, Takanori;
Watanabe, Masakatsu;
Kasai, Hiroshi;
Fujikawa, Kazuo

Publication type:

Article

Effects of Fe3O4 Magnetic Nanoparticles on A549 Cells.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 8, p. 15546, doi. 10.3390/ijms140815546

By:

Masatoshi Watanabe;
Misao Yoneda;
Ayaka Morohashi;
Yasuki Hori;
Daiki Okamoto;
Akiko Sato;
Daisuke Kurioka;
Tadashi Nittami;
Yoshifumi Hirokawa;
Taizo Shiraishi;
Kazuaki Kawai;
Hiroshi Kasai;
Yukari Totsuka

Publication type:

Article

Detection of a mouse OGG1 fragment during caspase-dependent apoptosis: Oxidative DNA damage and apoptosis.

Published in:

Cancer Science, 2004, v. 95, n. 8, p. 634, doi. 10.1111/j.1349-7006.2004.tb03321.x

By:

Hirano, Takeshi;
Kawai, Kazuaki;
Ootsuyama, Yuko;
Orimo, Hiroshi;
Kasai, Hiroshi

Publication type:

Article