Works by Hirasawa, Takashi

Results: 38

Utilization of Saccharomyces cerevisiae recombinant strain incapable of both ethanol and glycerol biosynthesis for anaerobic bioproduction.

Published in:

Applied Microbiology & Biotechnology, 2013, v. 97, n. 11, p. 4811, doi. 10.1007/s00253-013-4760-x

By:

Ida, Yoshihiro;
Hirasawa, Takashi;
Furusawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 92, n. 2, p. 347, doi. 10.1007/s00253-011-3559-x

By:

Yoshikawa, Katsunori;
Kojima, Yuta;
Nakajima, Tsubasa;
Furusawa, Chikara;
Hirasawa, Takashi;
Shimizu, Hiroshi

Publication type:

Article

Investigation of phosphorylation status of OdhI protein during penicillin- and Tween 40-triggered glutamate overproduction by Corynebacterium glutamicum.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 91, n. 1, p. 143, doi. 10.1007/s00253-011-3275-6

By:

Kim, Jongpill;
Hirasawa, Takashi;
Saito, Masaki;
Furusawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Saccharomyces cerevisiae and DNA microarray analyses: what did we learn from it for a better understanding and exploitation of yeast biotechnology?

Published in:

Applied Microbiology & Biotechnology, 2010, v. 87, n. 2, p. 391, doi. 10.1007/s00253-010-2582-7

By:

Hirasawa, Takashi;
Furusawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 86, n. 3, p. 911, doi. 10.1007/s00253-009-2360-6

By:

Kim, Jongpill;
Fukuda, Hirohisa;
Hirasawa, Takashi;
Nagahisa, Keisuke;
Nagai, Kazuo;
Wachi, Masaaki;
Shimizu, Hiroshi

Publication type:

Article

Investigating the effectiveness of DNA microarray analysis for identifying the genes involved in l-lactate production by Saccharomyces cerevisiae.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 84, n. 6, p. 1149, doi. 10.1007/s00253-009-2209-z

By:

Hirasawa, Takashi;
Ookubo, Aki;
Yoshikawa, Katsunori;
Nagahisa, Keisuke;
Furusawa, Chikara;
Sawai, Hideki;
Shimizu, Hiroshi

Publication type:

Article

Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 81, n. 6, p. 1097, doi. 10.1007/s00253-008-1743-4

By:

Kim, Jongpill;
Hirasawa, Takashi;
Sato, Yoshiyasu;
Nagahisa, Keisuke;
Furusawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Extracting the hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA microarray data using the self-organizing map: biosynthesis of amino acids.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 75, n. 2, p. 415, doi. 10.1007/s00253-007-0837-8

By:

Pandey, Gaurav;
Yoshikawa, Katsunori;
Hirasawa, Takashi;
Nagahisa, Keisuke;
Katakura, Yoshio;
Furusawa, Chikara;
Shimizu, Hiroshi;
Shioya, Suteaki

Publication type:

Article

Production of aromatic amino acids and their derivatives by Escherichia coli and Corynebacterium glutamicum.

Published in:

2025

By:

Hirasawa, Takashi;
Satoh, Yasuharu;
Koma, Daisuke

Publication type:

Literature Review

Loss of function of Hog1 improves glycerol assimilation in Saccharomyces cerevisiae.

Published in:

World Journal of Microbiology & Biotechnology, 2023, v. 39, n. 10, p. 1, doi. 10.1007/s11274-023-03696-z

By:

Sone, Masato;
Navanopparatsakul, Kantawat;
Takahashi, Shunsuke;
Furusawa, Chikara;
Hirasawa, Takashi

Publication type:

Article

Mutations in the ilvN gene mitigate growth inhibitory effect of cysteine in Corynebacterium glutamicum.

Published in:

Applied Microbiology & Biotechnology, 2025, v. 109, n. 1, p. 1, doi. 10.1007/s00253-025-13444-y

By:

Matsuhisa, Kazuho;
Ogawa, Katsuhiro;
Komata, Kento;
Hirasawa, Takashi

Publication type:

Article

Integrated Metabolic Flux and Omics Analysis of Synechocystis sp. PCC 6803 under Mixotrophic and Photoheterotrophic Conditions.

Published in:

Plant & Cell Physiology, 2014, v. 55, n. 9, p. 1605, doi. 10.1093/pcp/pcu091

By:

Nakajima, Tsubasa;
Kajihata, Shuichi;
Yoshikawa, Katsunori;
Matsuda, Fumio;
Furusawa, Chikara;
Hirasawa, Takashi;
Shimizu, Hiroshi

Publication type:

Article

Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae.

Published in:

Yeast, 2011, v. 28, n. 5, p. 349, doi. 10.1002/yea.1843

By:

Yoshikawa, Katsunori;
Tanaka, Tadamasa;
Ida, Yoshihiro;
Furusawa, Chikara;
Hirasawa, Takashi;
Shimizu, Hiroshi

Publication type:

Article

Effect of trehalose accumulation on response to saline stress in Saccharomyces cerevisiae.

Published in:

Yeast, 2009, v. 26, n. 1, p. 17, doi. 10.1002/yea.1646

By:

Mahmud, Siraje Arif;
Nagahisa, Keisuke;
Hirasawa, Takashi;
Yoshikawa, Katsunori;
Ashitani, Kengo;
Shimizu, Hiroshi

Publication type:

Article

Phenotypic convergence in bacterial adaptive evolution to ethanol stress.

Published in:

BMC Evolutionary Biology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12862-015-0454-6

By:

Takaaki Horinouchi;
Shingo Suzuki;
Takashi Hirasawa;
Naoaki Ono;
Tetsuya Yomo;
Hiroshi Shimizu;
Chikara Furusawa

Publication type:

Article

Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli.

Published in:

Microbial Cell Factories, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2859-13-64

By:

Kento Tokuyama;
Satoshi Ohno;
Katsunori Yoshikawa;
Takashi Hirasawa;
Shotaro Tanaka;
Chikara Furusawa;
Hiroshi Shimizu

Publication type:

Article

Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using <sup>13</sup> C metabolic flux analysis.

Published in:

Microbial Cell Factories, 2012, v. 11, n. 1, p. 87, doi. 10.1186/1475-2859-11-87

By:

Yuki Usui;
Takashi Hirasawa;
Chikara Furusawa;
Tomokazu Shirai;
Natsuko Yamamoto;
Hirotada Mori;
Hiroshi Shimizu

Publication type:

Article

Effectiveness of the Bacillus subtilis genome-reduced strain as an ethanol production host.

Published in:

Bioscience, Biotechnology & Biochemistry, 2022, v. 86, n. 4, p. 543, doi. 10.1093/bbb/zbac017

By:

Dita Grinanda;
Takashi Hirasawa

Publication type:

Article

Enhanced L-cysteine production by overexpressing potential L-cysteine exporter genes in an L-cysteine-producing recombinant strain of Corynebacterium glutamicum.

Published in:

Bioscience, Biotechnology & Biochemistry, 2019, v. 83, n. 12, p. 2390, doi. 10.1080/09168451.2019.1659715

By:

Kishino, Mayumi;
Kondoh, Mariko;
Hirasawa, Takashi

Publication type:

Article

Enhanced dipicolinic acid production during the stationary phase in <italic>Bacillus subtilis</italic> by blocking acetoin synthesis.

Published in:

Bioscience, Biotechnology & Biochemistry, 2015, v. 79, n. 12, p. 2073, doi. 10.1080/09168451.2015.1060843

By:

Toya, Yoshihiro;
Hirasawa, Takashi;
Ishikawa, Shu;
Chumsakul, Onuma;
Morimoto, Takuya;
Liu, Shenghao;
Masuda, Kenta;
Kageyama, Yasushi;
Ozaki, Katsuya;
Ogasawara, Naotake;
Shimizu, Hiroshi

Publication type:

Article

Metabolic engineering of Saccharomyces cerevisiae to improve succinic acid production based on metabolic profiling.

Published in:

Bioscience, Biotechnology & Biochemistry, 2014, v. 78, n. 1, p. 151, doi. 10.1080/09168451.2014.877816

By:

Yuma Ito;
Takashi Hirasawa;
Hiroshi Shimizu

Publication type:

Article

Improvement of L-Lactate Production by CYB2 Gene Disruption in a Recombinant Saccharomyces cerevisiae Strain under Low pH Condition.

Published in:

Bioscience, Biotechnology & Biochemistry, 2008, v. 72, n. 11, p. 3063, doi. 10.1271/bbb.80493

By:

Ookubo, Aki;
Hirasawa, Takashi;
Yoshikawa, Katsunori;
Nagahisa, Keisuke;
Furusawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Characterization of a Corynebacterium glutamicum dnaB mutant that shows temperature-sensitive growth and mini-cell formation.

Published in:

Archives of Microbiology, 2014, v. 196, n. 12, p. 871, doi. 10.1007/s00203-014-1026-7

By:

Uchida, Makoto;
Hirasawa, Takashi;
Wachi, Masaaki

Publication type:

Article

Constitutive expression of the global regulator AbrB restores the growth defect of a genome-reduced Bacillus subtilis strain and improves its metabolite production.

Published in:

DNA Research, 2022, v. 29, n. 3, p. 1, doi. 10.1093/dnares/dsac015

By:

Yamamoto, Junya;
Chumsakul, Onuma;
Toya, Yoshihiro;
Morimoto, Takuya;
Liu, Shenghao;
Masuda, Kenta;
Kageyama, Yasushi;
Hirasawa, Takashi;
Matsuda, Fumio;
Ogasawara, Naotake;
Shimizu, Hiroshi;
Yoshida, Ken-ichi;
Oshima, Taku;
Ishikawa, Shu

Publication type:

Article

<sup>13</sup>C-metabolic flux analysis for batch culture of Escherichia coli and its pyk and pgi gene knockout mutants based on mass isotopomer distribution of intracellular metabolites.

Published in:

Biotechnology Progress, 2010, v. 26, n. 4, p. 975, doi. 10.1002/btpr.420

By:

Toya, Yoshihiro;
Ishii, Nobuyoshi;
Nakahigashi, Kenji;
Hirasawa, Takashi;
Soga, Tomoyoshi;
Tomita, Masaru;
Shimizu, Kazuyuki

Publication type:

Article

Fluorescent Phospholipid Analogs as Microscopic Probes for Detection of the Mycolic Acid-Containing Layer in Corynebacterium glutamicum: Detecting Alterations in the Mycolic Acid-Containing Layer Following Ethambutol Treatment.

Published in:

Bioscience, Biotechnology & Biochemistry, 2005, v. 69, n. 11, p. 2051, doi. 10.1271/bbb.69.2051

By:

Kumagai, Yutaro;
Hirasawa, Takashi;
Hayakawa, Kenshi;
Nagai, Kazuo;
Wachi, Masaaki

Publication type:

Article

A Corynebacterium glutamicum rnhA recG Double Mutant Showing Lysozyme-sensitivity, Temperature-sensitive Growth, and UV-Sensitivity.

Published in:

Bioscience, Biotechnology & Biochemistry, 2003, v. 67, n. 11, p. 2416, doi. 10.1271/bbb.67.2416

By:

Hirasawa, Takashi;
Kumagai, Yutaro;
Nagai, Kazuo;
Wachi, Masaaki

Publication type:

Article

Induction of glutamic acid production by copper in Corynebacterium glutamicum.

Published in:

Applied Microbiology & Biotechnology, 2021, v. 105, n. 18, p. 6909, doi. 10.1007/s00253-021-11516-3

By:

Ogata, Shunsuke;
Hirasawa, Takashi

Publication type:

Article

l-Cysteine production by metabolically engineered Corynebacterium glutamicum.

Published in:

Applied Microbiology & Biotechnology, 2019, v. 103, n. 6, p. 2609, doi. 10.1007/s00253-019-09663-9

By:

Kondoh, Mariko;
Hirasawa, Takashi

Publication type:

Article

Potential of a Saccharomyces cerevisiae recombinant strain lacking ethanol and glycerol biosynthesis pathways in efficient anaerobic bioproduction.

Published in:

Bioengineered, 2014, v. 5, n. 2, p. 1, doi. 10.4161/bioe.26569

By:

Hirasawa, Takashi;
Ida, Yoshihiro;
Furuasawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Adaptation of Saccharomyces cerevisiae Cells to High Ethanol Concentration and Changes in Fatty Acid Composition of Membrane and Cell Size.

Published in:

PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002623

By:

Dinh, Thai Nho;
Nagahisa, Keisuke;
Hirasawa, Takashi;
Furusawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Integrated Analysis of the Transcriptome and Metabolome of <italic>Corynebacterium glutamicum</italic> during Penicillin‐Induced Glutamic Acid Production.

Published in:

Biotechnology Journal, 2018, v. 13, n. 5, p. 1, doi. 10.1002/biot.201700612

By:

Hirasawa, Takashi;
Saito, Masaki;
Yoshikawa, Katsunori;
Furusawa, Chikara;
Shmizu, Hiroshi

Publication type:

Article

Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions.

Published in:

Biotechnology Journal, 2013, v. 8, n. 5, p. 571, doi. 10.1002/biot.201200235

By:

Yoshikawa, Katsunori;
Hirasawa, Takashi;
Ogawa, Kenichi;
Hidaka, Yuki;
Nakajima, Tsubasa;
Furusawa, Chikara;
Shimizu, Hiroshi

Publication type:

Article

Adaptive Laboratory Evolution of Microorganisms: Methodology and Application for Bioproduction.

Published in:

Microorganisms, 2023, v. 11, n. 1, p. 92, doi. 10.3390/microorganisms11010092

By:

Hirasawa, Takashi;
Maeda, Tomoya

Publication type:

Article

Requirement of the LtsA Protein for Formation of the Mycolic Acid-Containing Layer on the Cell Surface of Corynebacterium glutamicum.

Published in:

Microorganisms, 2021, v. 9, n. 2, p. 409, doi. 10.3390/microorganisms9020409

By:

Kumagai, Yutaro;
Hirasawa, Takashi;
Wachi, Masaaki;
Pátek, Miroslav;
Burkovski, Andreas

Publication type:

Article

L-Glutamate production by lysozyme-sensitive Corynebacterium glutamicum ltsA mutant strains.

Published in:

BMC Biotechnology, 2001, v. 1, p. 1

By:

Hirasawa, Takashi;
Wachi, Masaaki;
Nagai, Kazuo

Publication type:

Article

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress.

Published in:

BMC Genomics, 2010, v. 11, n. 1, p. 1, doi. 10.1186/1471-2164-11-579

By:

Horinouchi, Takaaki;
Tamaoka, Kuniyasu;
Furusawa, Chikara;
Ono, Naoaki;
Suzuki, Shingo;
Hirasawa, Takashi;
Yomo, Tetsuya;
Shimizu, Hiroshi

Publication type:

Article

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress.

Published in:

BMC Genomics, 2010, v. 11, p. 579, doi. 10.1186/1471-2164-11-579

By:

Horinouchi, Takaaki;
Tamaoka, Kuniyasu;
Furusawa, Chikara;
Ono, Naoaki;
Suzuki, Shingo;
Hirasawa, Takashi;
Yomo, Tetsuya;
Shimizu, Hiroshi

Publication type:

Article