Works by Hippo, Yoshitaka

Results: 43

A high-throughput screening platform to identify MYCN expression inhibitors for liver cancer therapy.
Published in:
Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1486671
By:
- Xu, Yali;
- Mishra, Hricha;
- Furutani, Yutaka;
- Yanaka, Kaori;
- Nishimura, Hajime;
- Furuhata, Erina;
- Takahashi, Masataka;
- Gailhouste, Luc;
- Suenaga, Yusuke;
- Hippo, Yoshitaka;
- Yu, Wenkui;
- Matsuura, Tomokazu;
- Suzuki, Harukazu;
- Qin, Xian-Yang
Publication type:
Article
New DNA polymorphisms of human MMH/OGG1 gene: Prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.
Published in:
International Journal of Cancer, 1999, v. 80, n. 1, p. 18, doi. 10.1002/(SICI)1097-0215(19990105)80:1<18::AID-IJC4>3.0.CO;2-E
By:
- Ishida, Toshimitsu;
- Takashima, Rieko;
- Fukayama, Masashi;
- Hamada, Chikuma;
- Hippo, Yoshitaka;
- Fujii, Takeshi;
- Moriyama, Sachiko;
- Matsuba, Chikako;
- Nakahori, Yutaka;
- Morita, Hiroyuki;
- Yazaki, Yoshio;
- Kodama, Tatsuhiko;
- Nishimura, Susumu;
- Aburatani, Hiroyuki
Publication type:
Article
Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.
Published in:
Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0255-8
By:
- Kawaguchi, Makiko;
- Yamamoto, Koji;
- Takeda, Naoki;
- Fukushima, Tsuyoshi;
- Yamashita, Fumiki;
- Sato, Katsuaki;
- Kitamura, Kenichiro;
- Hippo, Yoshitaka;
- Janetka, James W.;
- Kataoka, Hiroaki
Publication type:
Article
Current Status of Patient-Derived Ovarian Cancer Models.
Published in:
Cells (2073-4409), 2019, v. 8, n. 5, p. 505, doi. 10.3390/cells8050505
By:
- Maru, Yoshiaki;
- Hippo, Yoshitaka
Publication type:
Article
Probing the tumorigenic potential of genetic interactions reconstituted in murine fallopian tube organoids.
Published in:
Journal of Pathology, 2021, v. 255, n. 2, p. 177, doi. 10.1002/path.5752
By:
- Maru, Yoshiaki;
- Tanaka, Naotake;
- Tatsumi, Yasutoshi;
- Nakamura, Yuki;
- Yao, Ryoji;
- Noda, Tetsuo;
- Itami, Makiko;
- Hippo, Yoshitaka
Publication type:
Article
A case of cervical clear cell carcinoma with serous component.
Published in:
Journal of Obstetrics & Gynaecology Research, 2021, v. 47, n. 7, p. 2551, doi. 10.1111/jog.14794
By:
- Ebisawa, Keiko;
- Sugiyama, Takahiro;
- Itami, Makiko;
- Maru, Yoshiaki;
- Hippo, Yoshitaka;
- Tanaka, Naotake
Publication type:
Article
1H, 13C and 15N backbone and side-chain resonance assignments of the human oncogenic protein NCYM.
Published in:
Biomolecular NMR Assignments, 2024, v. 18, n. 1, p. 65, doi. 10.1007/s12104-024-10169-3
By:
- Mouhand, Assia;
- Nakatani, Kazuma;
- Kono, Fumiaki;
- Hippo, Yoshitaka;
- Matsuo, Tatsuhito;
- Barthe, Philippe;
- Peters, Judith;
- Suenaga, Yusuke;
- Tamada, Taro;
- Roumestand, Christian
Publication type:
Article
Non-neuronal acetylcholine as an endogenous regulator of proliferation and differentiation of Lgr5-positive stem cells in mice.
Published in:
FEBS Journal, 2014, v. 281, n. 20, p. 4672, doi. 10.1111/febs.12974
By:
- Takahashi, Toshio;
- Ohnishi, Hiroe;
- Sugiura, Yuki;
- Honda, Kurara;
- Suematsu, Makoto;
- Kawasaki, Takashi;
- Deguchi, Tomonori;
- Fujii, Takeshi;
- Orihashi, Kaoru;
- Hippo, Yoshitaka;
- Watanabe, Takehiro;
- Yamagaki, Tohru;
- Yuba, Shunsuke
Publication type:
Article
Ex vivo model of non‑small cell lung cancer using mouse lung epithelial cells.
Published in:
Oncology Letters, 2017, v. 14, n. 6, p. 6863, doi. 10.3892/ol.2017.7098
By:
- Taku Sato;
- Mami Morita;
- Ryota Tanaka;
- Yui Inoue;
- Miyuki Nomura;
- Yoshimi Sakamoto;
- Koh Miura;
- Shigemi Ito;
- Ikuro Sato;
- Nobuyuki Tanaka;
- Jiro Abe;
- Satomi Takahashi;
- Masaaki Kawai;
- Masami Sato;
- Yoshitaka Hippo;
- Hiroshi Shima;
- Yoshinori Okada;
- Nobuhiro Tanuma
Publication type:
Article
Pentagamavunone-1 Suppresses MYCN-Positive HuH-7 Cancer Cell Growth Via Mitotic Arrest In Vitro.
Published in:
Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2024, v. 35, n. 4, p. 649
By:
- Moordiani;
- Novitasari, Dhania;
- Susidarti, Ratna Asmah;
- Ikawati, Muthi';
- Kato, Jun-Ya;
- Hippo, Yoshitaka;
- Suenaga, Yusuke;
- Meiyanto, Edy
Publication type:
Article
Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance.
Published in:
Frontiers in Oncology, 2024, p. 01, doi. 10.3389/fonc.2024.1237378
By:
- Kazuma Nakatani;
- Hiroyuki Kogashi;
- Takanori Miyamoto;
- Taiki Setoguchi;
- Tetsushi Sakuma;
- Kazuto Kugou;
- Yoshinori Hasegawa;
- Takashi Yamamoto;
- Yoshitaka Hippo;
- Yusuke Suenaga
Publication type:
Article
Structural characterization of human de novo protein NCYM and its complex with a newly identified DNA aptamer using atomic force microscopy and small-angle X-ray scattering.
Published in:
Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1213678
By:
- Seigi Yamamoto;
- Fumiaki Kono;
- Kazuma Nakatani;
- Miwako Hirose;
- Katsunori Horii;
- Yoshitaka Hippo;
- Taro Tamada;
- Yusuke Suenaga;
- Tatsuhito Matsuo
Publication type:
Article
PGV-1 Causes Disarrangement of Spindle Microtubule Organization Resulting in Aberrant Mitosis in HLF and HuH6 Cells Associated with Altered MYCN Status.
Published in:
Advanced Pharmaceutical Bulletin, 2024, v. 14, n. 3, p. 665, doi. 10.34172/apb.2024.058
By:
- Nugraheni, Nadzifa;
- Zulfin, Ummi Maryam;
- Lestari, Beni;
- Hapsari, Novia Permata;
- Ikawati, Muthi;
- Utomo, Rohmad Yudi;
- Suenaga, Yusuke;
- Hippo, Yoshitaka;
- Meiyanto, Edy
Publication type:
Article
β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 13, p. 3344, doi. 10.3390/ijms20133344
By:
- Aono, Shiori;
- Hatanaka, Ayari;
- Hatanaka, Atsushi;
- Gao, Yue;
- Hippo, Yoshitaka;
- Taketo, Makoto Mark;
- Waku, Tsuyoshi;
- Kobayashi, Akira
Publication type:
Article
The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma.
Published in:
Modern Pathology, 2005, v. 18, n. 12, p. 1591, doi. 10.1038/modpathol.3800436
By:
- Yamauchi, Naoko;
- Watanabe, Akira;
- Hishinuma, Michiyo;
- Ohashi, Ken-ichi;
- Midorikawa, Yutaka;
- Morishita, Yasuyuki;
- Niki, Toshiro;
- Shibahara, Junji;
- Mori, Masaya;
- Makuuchi, Masatoshi;
- Hippo, Yoshitaka;
- Kodama, Tatsuhiko;
- Iwanari, Hiroko;
- Aburatani, Hiroyuki;
- Fukayama, Masashi
Publication type:
Article
Kras activation in endometrial organoids drives cellular transformation and epithelial-mesenchymal transition.
Published in:
Oncogenesis, 2021, v. 10, n. 6, p. 1, doi. 10.1038/s41389-021-00337-8
By:
- Maru, Yoshiaki;
- Tanaka, Naotake;
- Tatsumi, Yasutoshi;
- Nakamura, Yuki;
- Itami, Makiko;
- Hippo, Yoshitaka
Publication type:
Article
Two-Way Development of the Genetic Model for Endometrial Tumorigenesis in Mice: Current and Future Perspectives.
Published in:
Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.798628
By:
- Maru, Yoshiaki;
- Hippo, Yoshitaka
Publication type:
Article
An organoid-based carcinogenesis model induced by in vitro chemical treatment.
Published in:
Carcinogenesis, 2020, v. 41, n. 10, p. 1444, doi. 10.1093/carcin/bgaa011
By:
- Naruse, Mie;
- Masui, Ryoichi;
- Ochiai, Masako;
- Maru, Yoshiaki;
- Hippo, Yoshitaka;
- Imai, Toshio
Publication type:
Article
Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis.
Published in:
Carcinogenesis, 2020, v. 41, n. 4, p. 490, doi. 10.1093/carcin/bgz122
By:
- Matsuura, Tetsuya;
- Maru, Yoshiaki;
- Izumiya, Masashi;
- Hoshi, Daisuke;
- Kato, Shingo;
- Ochiai, Masako;
- Hori, Mika;
- Yamamoto, Shogo;
- Tatsuno, Kenji;
- Imai, Toshio;
- Aburatani, Hiroyuki;
- Nakajima, Atsushi;
- Hippo, Yoshitaka
Publication type:
Article
Kras-driven heterotopic tumor development from hepatobiliary organoids.
Published in:
Carcinogenesis, 2019, v. 40, n. 9, p. 1142, doi. 10.1093/carcin/bgz024
By:
- Ochiai, Masako;
- Yoshihara, Yasunori;
- Maru, Yoshiaki;
- Matsuura, Tetsuya;
- Izumiya, Masashi;
- Imai, Toshio;
- Hippo, Yoshitaka
Publication type:
Article
Conditional knockout of the leptin receptor in the colonic epithelium revealed the local effects of leptin receptor signaling in the progression of colonic tumors in mice.
Published in:
Carcinogenesis, 2014, v. 35, n. 9, p. 2134, doi. 10.1093/carcin/bgu135
By:
- Higurashi, Takuma;
- Endo, Hiroki;
- Uchiyama, Takashi;
- Uchiyama, Shiori;
- Yamada, Eiji;
- Ohkubo, Hidenori;
- Sakai, Eiji;
- Takahashi, Hirokazu;
- Maeda, Shin;
- Wada, Koichiro;
- Natsumeda, Yutaka;
- Hippo, Yoshitaka;
- Nakajima, Atsushi;
- Nakagama, Hitoshi
Publication type:
Article
The potential of organoids in toxicologic pathology: Histopathological and immunohistochemical evaluation of a mouse normal tissue-derived organoid-based carcinogenesis model.
Published in:
2022
By:
- Rikako Ishigamori;
- Mie Naruse;
- Akihiro Hirata;
- Yoshiaki Maru;
- Yoshitaka Hippo;
- Toshio Imai
Publication type:
Literature Review
Number of aberrant crypt foci in the rectum is a useful surrogate marker of colorectal adenoma recurrence.
Published in:
Digestive Endoscopy, 2012, v. 24, n. 5, p. 353, doi. 10.1111/j.1443-1661.2012.01289.x
By:
- Uchiyama, Takashi;
- Takahashi, Hirokazu;
- Endo, Hiroki;
- Kato, Shingo;
- Sakai, Eiji;
- Hosono, Kunihiro;
- Yoneda, Masato;
- Inamori, Masahiko;
- Hippo, Yoshitaka;
- Nakagama, Hitoshi;
- Nakajima, Atsushi
Publication type:
Article
Editorial: Development of in vitro toxicology methods using organoid systems and toxicogenomic approaches.
Published in:
Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.1030580
By:
- Toshio Imai;
- Yoshitaka Hippo
Publication type:
Article
CX3CL1 Overexpression Prevents the Formation of Lung Metastases in Trastuzumab-Treated MDA-MB-453-Based Humanized Tumor Mice (HTM).
Published in:
Cancers, 2021, v. 13, n. 10, p. 2459, doi. 10.3390/cancers13102459
By:
- Wege, Anja Kathrin;
- Dreyer, Tobias F.;
- Teoman, Attila;
- Ortmann, Olaf;
- Brockhoff, Gero;
- Bronger, Holger;
- Hippo, Yoshitaka
Publication type:
Article
Recent Advances in Implantation-Based Genetic Modeling of Biliary Carcinogenesis in Mice.
Published in:
Cancers, 2021, v. 13, n. 10, p. 2292, doi. 10.3390/cancers13102292
By:
- Izumiya, Masashi;
- Kato, Shingo;
- Hippo, Yoshitaka;
- Vitale, Alessandro
Publication type:
Article
Mouse Models for Deciphering the Impact of Homologous Recombination on Tumorigenesis.
Published in:
Cancers, 2021, v. 13, n. 9, p. 2083, doi. 10.3390/cancers13092083
By:
- Matos-Rodrigues, Gabriel;
- Martini, Emmanuelle;
- Lopez, Bernard S.;
- Hippo, Yoshitaka
Publication type:
Article
Colibactin-Producing Escherichia coli Induce the Formation of Invasive Carcinomas in a Chronic Inflammation-Associated Mouse Model.
Published in:
Cancers, 2021, v. 13, n. 9, p. 2060, doi. 10.3390/cancers13092060
By:
- Salesse, Laurène;
- Lucas, Cécily;
- Hoang, My Hanh Thi;
- Sauvanet, Pierre;
- Rezard, Alexandra;
- Rosenstiel, Philip;
- Damon-Soubeyrand, Christelle;
- Barnich, Nicolas;
- Godfraind, Catherine;
- Dalmasso, Guillaume;
- Nguyen, Hang Thi Thu;
- Hippo, Yoshitaka
Publication type:
Article
Cache Domain Containing 1 Is a Novel Marker of Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis.
Published in:
Cancers, 2021, v. 13, n. 6, p. 1216, doi. 10.3390/cancers13061216
By:
- Kakehashi, Anna;
- Chariyakornkul, Arpamas;
- Suzuki, Shugo;
- Khuanphram, Napaporn;
- Tatsumi, Kumiko;
- Yamano, Shotaro;
- Fujioka, Masaki;
- Gi, Min;
- Wongpoomchai, Rawiwan;
- Wanibuchi, Hideki;
- Hippo, Yoshitaka
Publication type:
Article
Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics.
Published in:
Cancers, 2021, v. 13, n. 5, p. 1126, doi. 10.3390/cancers13051126
By:
- Franceschini, Natasja;
- Verbruggen, Bas;
- Tryfonidou, Marianna A.;
- Kruisselbrink, Alwine B.;
- Baelde, Hans;
- de Visser, Karin E.;
- Szuhai, Karoly;
- Cleton-Jansen, Anne-Marie;
- Bovée, Judith V. M. G.;
- Hippo, Yoshitaka
Publication type:
Article
The Chicken Chorioallantoic Membrane Tumor Assay as a Relevant In Vivo Model to Study the Impact of Hypoxia on Tumor Progression and Metastasis.
Published in:
Cancers, 2021, v. 13, n. 5, p. 1093, doi. 10.3390/cancers13051093
By:
- Harper, Kelly;
- Yatsyna, Anna;
- Charbonneau, Martine;
- Brochu-Gaudreau, Karine;
- Perreault, Alexis;
- Jeldres, Claudio;
- McDonald, Patrick P.;
- Dubois, Claire M.;
- Hippo, Yoshitaka
Publication type:
Article
Inflammation-Related Carcinogenesis: Lessons from Animal Models to Clinical Aspects.
Published in:
Cancers, 2021, v. 13, n. 4, p. 921, doi. 10.3390/cancers13040921
By:
- Okada, Futoshi;
- Izutsu, Runa;
- Goto, Keisuke;
- Osaki, Mitsuhiko;
- Hippo, Yoshitaka
Publication type:
Article
Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine Cervix.
Published in:
Cancers, 2020, v. 12, n. 3, p. 694, doi. 10.3390/cancers12030694
By:
- Maru, Yoshiaki;
- Kawata, Akira;
- Taguchi, Ayumi;
- Ishii, Yoshiyuki;
- Baba, Satoshi;
- Mori, Mayuyo;
- Nagamatsu, Takeshi;
- Oda, Katsutoshi;
- Kukimoto, Iwao;
- Osuga, Yutaka;
- Fujii, Tomoyuki;
- Hippo, Yoshitaka
Publication type:
Article
Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model.
Published in:
BMC Biology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12915-021-01147-5
By:
- Ono, Hanako;
- Arai, Yasuhito;
- Furukawa, Eisaku;
- Narushima, Daichi;
- Matsuura, Tetsuya;
- Nakamura, Hiromi;
- Shiokawa, Daisuke;
- Nagai, Momoko;
- Imai, Toshio;
- Mimori, Koshi;
- Okamoto, Koji;
- Hippo, Yoshitaka;
- Shibata, Tatsuhiro;
- Kato, Mamoru
Publication type:
Article
The Combination of Sorafenib and PGV‐1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c‐Myc Suppression in an Additive Manner: In Vitro Studies.
Published in:
Advances in Pharmacological & Pharmaceutical Sciences, 2024, v. 2024, p. 1, doi. 10.1155/adpp/4297953
By:
- Novitasari, Dhania;
- Nakamae, Ikuko;
- Yoneda-Kato, Noriko;
- Kato, Jun-ya;
- Hippo, Yoshitaka;
- Suenaga, Yusuke;
- Putri, Dyaningtyas Dewi Pamungkas;
- Meiyanto, Edy;
- Ikawati, Muthi';
- Ooi, Der Jiun
Publication type:
Article
Anticancer effect of a pyrrole‐imidazole polyamide‐triphenylphosphonium conjugate selectively targeting a common mitochondrial DNA cancer risk variant in cervical cancer cells.
Published in:
International Journal of Cancer, 2023, v. 152, n. 5, p. 962, doi. 10.1002/ijc.34319
By:
- Yao, Jihang;
- Takenaga, Keizo;
- Koshikawa, Nobuko;
- Kida, Yuki;
- Lin, Jason;
- Watanabe, Takayoshi;
- Maru, Yoshiaki;
- Hippo, Yoshitaka;
- Yamamoto, Seigi;
- Zhu, Yuyan;
- Nagase, Hiroki
Publication type:
Article
Bridging toxicological properties of environmental chemicals between animals and humans using healthy organoid systems.
Published in:
Journal of Toxicological Sciences, 2024, v. 49, n. 10, p. 425, doi. 10.2131/jts.49.425
By:
- Toshio Imai;
- Rikako Ishigamori;
- Mie Naruse;
- Masako Ochiai;
- Yoshiaki Maru;
- Yoshitaka Hippo;
- Yukari Totsuka
Publication type:
Article
Derivation of pancreatic acinar cell carcinoma cell line HS‐1 as a patient‐derived tumor organoid.
Published in:
Cancer Science, 2023, v. 114, n. 3, p. 1165, doi. 10.1111/cas.15656
By:
- Hoshi, Daisuke;
- Kita, Emiri;
- Maru, Yoshiaki;
- Kogashi, Hiroyuki;
- Nakamura, Yuki;
- Tatsumi, Yasutoshi;
- Shimozato, Osamu;
- Nakamura, Kazuyoshi;
- Sudo, Kentaro;
- Tsujimoto, Akiko;
- Yokoyama, Ryo;
- Kato, Atsushi;
- Ushiku, Tetsuo;
- Fukayama, Masashi;
- Itami, Makiko;
- Yamaguchi, Taketo;
- Hippo, Yoshitaka
Publication type:
Article
Onset of Quiescence Following p53 Mediated Down- Regulation of H2AX in Normal Cells.
Published in:
PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023432
By:
- Atsumi, Yuko;
- Fujimori, Hiroaki;
- Fukuda, Hirokazu;
- Inase, Aki;
- Shinohe, Keitaro;
- Yoshioka, Yoshiko;
- Shikanai, Mima;
- Ichijima, Yosuke;
- Unno, Junya;
- Mizutani, Shuki;
- Tsuchiya, Naoto;
- Hippo, Yoshitaka;
- Nakagama, Hitoshi;
- Masutani, Mitsuko;
- Teraoka, Hirobumi;
- Yoshioka, Ken-ichi
Publication type:
Article
Establishment and characterization of patient‐derived organoids from a young patient with cervical clear cell carcinoma.
Published in:
Cancer Science, 2019, v. 110, n. 9, p. 2992, doi. 10.1111/cas.14119
By:
- Maru, Yoshiaki;
- Tanaka, Naotake;
- Ebisawa, Keiko;
- Odaka, Akiko;
- Sugiyama, Takahiro;
- Itami, Makiko;
- Hippo, Yoshitaka
Publication type:
Article
Shortcuts to intestinal carcinogenesis by genetic engineering in organoids.
Published in:
Cancer Science, 2019, v. 110, n. 3, p. 858, doi. 10.1111/cas.13938
By:
- Maru, Yoshiaki;
- Onuma, Kunishige;
- Ochiai, Masako;
- Imai, Toshio;
- Hippo, Yoshitaka
Publication type:
Article
Newly defined aberrant crypt foci as a marker for dysplasia in the rat colon.
Published in:
Cancer Science, 2014, v. 105, n. 8, p. 943, doi. 10.1111/cas.12446
By:
- Ochiai, Masako;
- Hippo, Yoshitaka;
- Izumiya, Masashi;
- Watanabe, Masatoshi;
- Nakagama, Hitoshi
Publication type:
Article
Overexpression of MUC13 is associated with intestinal-type gastric cancer.
Published in:
Cancer Science, 2005, v. 96, n. 5, p. 265, doi. 10.1111/j.1349-7006.2005.00043.x
By:
- Shimamura, Takahiro;
- Ito, Hirotaka;
- Shibahara, Junji;
- Watanabe, Akira;
- Hippo, Yoshitaka;
- Taniguchi, Hirokazu;
- Chen, Yongxin;
- Kashima, Takeshi;
- Ohtomo, Toshihiko;
- Tanioka, Fumihiko;
- Iwanari, Hiroko;
- Kodama, Tatsuhiko;
- Kazui, Teruhisa;
- Sugimura, Haruhiko;
- Fukayama, Masashi;
- Aburatani, Hiroyuki
Publication type:
Article