Works by Hippo, Yoshitaka

Results: 43

The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma.

Published in:

Modern Pathology, 2005, v. 18, n. 12, p. 1591, doi. 10.1038/modpathol.3800436

By:

Yamauchi, Naoko;
Watanabe, Akira;
Hishinuma, Michiyo;
Ohashi, Ken-ichi;
Midorikawa, Yutaka;
Morishita, Yasuyuki;
Niki, Toshiro;
Shibahara, Junji;
Mori, Masaya;
Makuuchi, Masatoshi;
Hippo, Yoshitaka;
Kodama, Tatsuhiko;
Iwanari, Hiroko;
Aburatani, Hiroyuki;
Fukayama, Masashi

Publication type:

Article

The Combination of Sorafenib and PGV‐1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c‐Myc Suppression in an Additive Manner: In Vitro Studies.

Published in:

Advances in Pharmacological & Pharmaceutical Sciences, 2024, v. 2024, p. 1, doi. 10.1155/adpp/4297953

By:

Novitasari, Dhania;
Nakamae, Ikuko;
Yoneda-Kato, Noriko;
Kato, Jun-ya;
Hippo, Yoshitaka;
Suenaga, Yusuke;
Putri, Dyaningtyas Dewi Pamungkas;
Meiyanto, Edy;
Ikawati, Muthi';
Ooi, Der Jiun

Publication type:

Article

Number of aberrant crypt foci in the rectum is a useful surrogate marker of colorectal adenoma recurrence.

Published in:

Digestive Endoscopy, 2012, v. 24, n. 5, p. 353, doi. 10.1111/j.1443-1661.2012.01289.x

By:

Uchiyama, Takashi;
Takahashi, Hirokazu;
Endo, Hiroki;
Kato, Shingo;
Sakai, Eiji;
Hosono, Kunihiro;
Yoneda, Masato;
Inamori, Masahiko;
Hippo, Yoshitaka;
Nakagama, Hitoshi;
Nakajima, Atsushi

Publication type:

Article

CX3CL1 Overexpression Prevents the Formation of Lung Metastases in Trastuzumab-Treated MDA-MB-453-Based Humanized Tumor Mice (HTM).

Published in:

Cancers, 2021, v. 13, n. 10, p. 2459, doi. 10.3390/cancers13102459

By:

Wege, Anja Kathrin;
Dreyer, Tobias F.;
Teoman, Attila;
Ortmann, Olaf;
Brockhoff, Gero;
Bronger, Holger;
Hippo, Yoshitaka

Publication type:

Article

Recent Advances in Implantation-Based Genetic Modeling of Biliary Carcinogenesis in Mice.

Published in:

Cancers, 2021, v. 13, n. 10, p. 2292, doi. 10.3390/cancers13102292

By:

Izumiya, Masashi;
Kato, Shingo;
Hippo, Yoshitaka;
Vitale, Alessandro

Publication type:

Article

Mouse Models for Deciphering the Impact of Homologous Recombination on Tumorigenesis.

Published in:

Cancers, 2021, v. 13, n. 9, p. 2083, doi. 10.3390/cancers13092083

By:

Matos-Rodrigues, Gabriel;
Martini, Emmanuelle;
Lopez, Bernard S.;
Hippo, Yoshitaka

Publication type:

Article

Colibactin-Producing Escherichia coli Induce the Formation of Invasive Carcinomas in a Chronic Inflammation-Associated Mouse Model.

Published in:

Cancers, 2021, v. 13, n. 9, p. 2060, doi. 10.3390/cancers13092060

By:

Salesse, Laurène;
Lucas, Cécily;
Hoang, My Hanh Thi;
Sauvanet, Pierre;
Rezard, Alexandra;
Rosenstiel, Philip;
Damon-Soubeyrand, Christelle;
Barnich, Nicolas;
Godfraind, Catherine;
Dalmasso, Guillaume;
Nguyen, Hang Thi Thu;
Hippo, Yoshitaka

Publication type:

Article

Cache Domain Containing 1 Is a Novel Marker of Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis.

Published in:

Cancers, 2021, v. 13, n. 6, p. 1216, doi. 10.3390/cancers13061216

By:

Kakehashi, Anna;
Chariyakornkul, Arpamas;
Suzuki, Shugo;
Khuanphram, Napaporn;
Tatsumi, Kumiko;
Yamano, Shotaro;
Fujioka, Masaki;
Gi, Min;
Wongpoomchai, Rawiwan;
Wanibuchi, Hideki;
Hippo, Yoshitaka

Publication type:

Article

Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics.

Published in:

Cancers, 2021, v. 13, n. 5, p. 1126, doi. 10.3390/cancers13051126

By:

Franceschini, Natasja;
Verbruggen, Bas;
Tryfonidou, Marianna A.;
Kruisselbrink, Alwine B.;
Baelde, Hans;
de Visser, Karin E.;
Szuhai, Karoly;
Cleton-Jansen, Anne-Marie;
Bovée, Judith V. M. G.;
Hippo, Yoshitaka

Publication type:

Article

The Chicken Chorioallantoic Membrane Tumor Assay as a Relevant In Vivo Model to Study the Impact of Hypoxia on Tumor Progression and Metastasis.

Published in:

Cancers, 2021, v. 13, n. 5, p. 1093, doi. 10.3390/cancers13051093

By:

Harper, Kelly;
Yatsyna, Anna;
Charbonneau, Martine;
Brochu-Gaudreau, Karine;
Perreault, Alexis;
Jeldres, Claudio;
McDonald, Patrick P.;
Dubois, Claire M.;
Hippo, Yoshitaka

Publication type:

Article

Inflammation-Related Carcinogenesis: Lessons from Animal Models to Clinical Aspects.

Published in:

Cancers, 2021, v. 13, n. 4, p. 921, doi. 10.3390/cancers13040921

By:

Okada, Futoshi;
Izutsu, Runa;
Goto, Keisuke;
Osaki, Mitsuhiko;
Hippo, Yoshitaka

Publication type:

Article

Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine Cervix.

Published in:

Cancers, 2020, v. 12, n. 3, p. 694, doi. 10.3390/cancers12030694

By:

Maru, Yoshiaki;
Kawata, Akira;
Taguchi, Ayumi;
Ishii, Yoshiyuki;
Baba, Satoshi;
Mori, Mayuyo;
Nagamatsu, Takeshi;
Oda, Katsutoshi;
Kukimoto, Iwao;
Osuga, Yutaka;
Fujii, Tomoyuki;
Hippo, Yoshitaka

Publication type:

Article

Probing the tumorigenic potential of genetic interactions reconstituted in murine fallopian tube organoids.

Published in:

Journal of Pathology, 2021, v. 255, n. 2, p. 177, doi. 10.1002/path.5752

By:

Maru, Yoshiaki;
Tanaka, Naotake;
Tatsumi, Yasutoshi;
Nakamura, Yuki;
Yao, Ryoji;
Noda, Tetsuo;
Itami, Makiko;
Hippo, Yoshitaka

Publication type:

Article

The potential of organoids in toxicologic pathology: Histopathological and immunohistochemical evaluation of a mouse normal tissue-derived organoid-based carcinogenesis model.

Published in:

2022

By:

Rikako Ishigamori;
Mie Naruse;
Akihiro Hirata;
Yoshiaki Maru;
Yoshitaka Hippo;
Toshio Imai

Publication type:

Literature Review

Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0255-8

By:

Kawaguchi, Makiko;
Yamamoto, Koji;
Takeda, Naoki;
Fukushima, Tsuyoshi;
Yamashita, Fumiki;
Sato, Katsuaki;
Kitamura, Kenichiro;
Hippo, Yoshitaka;
Janetka, James W.;
Kataoka, Hiroaki

Publication type:

Article

Pentagamavunone-1 Suppresses MYCN-Positive HuH-7 Cancer Cell Growth Via Mitotic Arrest In Vitro.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2024, v. 35, n. 4, p. 649

By:

Moordiani;
Novitasari, Dhania;
Susidarti, Ratna Asmah;
Ikawati, Muthi';
Kato, Jun-Ya;
Hippo, Yoshitaka;
Suenaga, Yusuke;
Meiyanto, Edy

Publication type:

Article

An organoid-based carcinogenesis model induced by in vitro chemical treatment.

Published in:

Carcinogenesis, 2020, v. 41, n. 10, p. 1444, doi. 10.1093/carcin/bgaa011

By:

Naruse, Mie;
Masui, Ryoichi;
Ochiai, Masako;
Maru, Yoshiaki;
Hippo, Yoshitaka;
Imai, Toshio

Publication type:

Article

Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis.

Published in:

Carcinogenesis, 2020, v. 41, n. 4, p. 490, doi. 10.1093/carcin/bgz122

By:

Matsuura, Tetsuya;
Maru, Yoshiaki;
Izumiya, Masashi;
Hoshi, Daisuke;
Kato, Shingo;
Ochiai, Masako;
Hori, Mika;
Yamamoto, Shogo;
Tatsuno, Kenji;
Imai, Toshio;
Aburatani, Hiroyuki;
Nakajima, Atsushi;
Hippo, Yoshitaka

Publication type:

Article

Kras-driven heterotopic tumor development from hepatobiliary organoids.

Published in:

Carcinogenesis, 2019, v. 40, n. 9, p. 1142, doi. 10.1093/carcin/bgz024

By:

Ochiai, Masako;
Yoshihara, Yasunori;
Maru, Yoshiaki;
Matsuura, Tetsuya;
Izumiya, Masashi;
Imai, Toshio;
Hippo, Yoshitaka

Publication type:

Article

Conditional knockout of the leptin receptor in the colonic epithelium revealed the local effects of leptin receptor signaling in the progression of colonic tumors in mice.

Published in:

Carcinogenesis, 2014, v. 35, n. 9, p. 2134, doi. 10.1093/carcin/bgu135

By:

Higurashi, Takuma;
Endo, Hiroki;
Uchiyama, Takashi;
Uchiyama, Shiori;
Yamada, Eiji;
Ohkubo, Hidenori;
Sakai, Eiji;
Takahashi, Hirokazu;
Maeda, Shin;
Wada, Koichiro;
Natsumeda, Yutaka;
Hippo, Yoshitaka;
Nakajima, Atsushi;
Nakagama, Hitoshi

Publication type:

Article

Non-neuronal acetylcholine as an endogenous regulator of proliferation and differentiation of Lgr5-positive stem cells in mice.

Published in:

FEBS Journal, 2014, v. 281, n. 20, p. 4672, doi. 10.1111/febs.12974

By:

Takahashi, Toshio;
Ohnishi, Hiroe;
Sugiura, Yuki;
Honda, Kurara;
Suematsu, Makoto;
Kawasaki, Takashi;
Deguchi, Tomonori;
Fujii, Takeshi;
Orihashi, Kaoru;
Hippo, Yoshitaka;
Watanabe, Takehiro;
Yamagaki, Tohru;
Yuba, Shunsuke

Publication type:

Article

New DNA polymorphisms of human MMH/OGG1 gene: Prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.

Published in:

International Journal of Cancer, 1999, v. 80, n. 1, p. 18, doi. 10.1002/(SICI)1097-0215(19990105)80:1<18::AID-IJC4>3.0.CO;2-E

By:

Ishida, Toshimitsu;
Takashima, Rieko;
Fukayama, Masashi;
Hamada, Chikuma;
Hippo, Yoshitaka;
Fujii, Takeshi;
Moriyama, Sachiko;
Matsuba, Chikako;
Nakahori, Yutaka;
Morita, Hiroyuki;
Yazaki, Yoshio;
Kodama, Tatsuhiko;
Nishimura, Susumu;
Aburatani, Hiroyuki

Publication type:

Article

Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model.

Published in:

BMC Biology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12915-021-01147-5

By:

Ono, Hanako;
Arai, Yasuhito;
Furukawa, Eisaku;
Narushima, Daichi;
Matsuura, Tetsuya;
Nakamura, Hiromi;
Shiokawa, Daisuke;
Nagai, Momoko;
Imai, Toshio;
Mimori, Koshi;
Okamoto, Koji;
Hippo, Yoshitaka;
Shibata, Tatsuhiro;
Kato, Mamoru

Publication type:

Article

Ex vivo model of non‑small cell lung cancer using mouse lung epithelial cells.

Published in:

Oncology Letters, 2017, v. 14, n. 6, p. 6863, doi. 10.3892/ol.2017.7098

By:

Taku Sato;
Mami Morita;
Ryota Tanaka;
Yui Inoue;
Miyuki Nomura;
Yoshimi Sakamoto;
Koh Miura;
Shigemi Ito;
Ikuro Sato;
Nobuyuki Tanaka;
Jiro Abe;
Satomi Takahashi;
Masaaki Kawai;
Masami Sato;
Yoshitaka Hippo;
Hiroshi Shima;
Yoshinori Okada;
Nobuhiro Tanuma

Publication type:

Article

Editorial: Development of in vitro toxicology methods using organoid systems and toxicogenomic approaches.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.1030580

By:

Toshio Imai;
Yoshitaka Hippo

Publication type:

Article

Anticancer effect of a pyrrole‐imidazole polyamide‐triphenylphosphonium conjugate selectively targeting a common mitochondrial DNA cancer risk variant in cervical cancer cells.

Published in:

International Journal of Cancer, 2023, v. 152, n. 5, p. 962, doi. 10.1002/ijc.34319

By:

Yao, Jihang;
Takenaga, Keizo;
Koshikawa, Nobuko;
Kida, Yuki;
Lin, Jason;
Watanabe, Takayoshi;
Maru, Yoshiaki;
Hippo, Yoshitaka;
Yamamoto, Seigi;
Zhu, Yuyan;
Nagase, Hiroki

Publication type:

Article

Derivation of pancreatic acinar cell carcinoma cell line HS‐1 as a patient‐derived tumor organoid.

Published in:

Cancer Science, 2023, v. 114, n. 3, p. 1165, doi. 10.1111/cas.15656

By:

Hoshi, Daisuke;
Kita, Emiri;
Maru, Yoshiaki;
Kogashi, Hiroyuki;
Nakamura, Yuki;
Tatsumi, Yasutoshi;
Shimozato, Osamu;
Nakamura, Kazuyoshi;
Sudo, Kentaro;
Tsujimoto, Akiko;
Yokoyama, Ryo;
Kato, Atsushi;
Ushiku, Tetsuo;
Fukayama, Masashi;
Itami, Makiko;
Yamaguchi, Taketo;
Hippo, Yoshitaka

Publication type:

Article

Establishment and characterization of patient‐derived organoids from a young patient with cervical clear cell carcinoma.

Published in:

Cancer Science, 2019, v. 110, n. 9, p. 2992, doi. 10.1111/cas.14119

By:

Maru, Yoshiaki;
Tanaka, Naotake;
Ebisawa, Keiko;
Odaka, Akiko;
Sugiyama, Takahiro;
Itami, Makiko;
Hippo, Yoshitaka

Publication type:

Article

Shortcuts to intestinal carcinogenesis by genetic engineering in organoids.

Published in:

Cancer Science, 2019, v. 110, n. 3, p. 858, doi. 10.1111/cas.13938

By:

Maru, Yoshiaki;
Onuma, Kunishige;
Ochiai, Masako;
Imai, Toshio;
Hippo, Yoshitaka

Publication type:

Article

Newly defined aberrant crypt foci as a marker for dysplasia in the rat colon.

Published in:

Cancer Science, 2014, v. 105, n. 8, p. 943, doi. 10.1111/cas.12446

By:

Ochiai, Masako;
Hippo, Yoshitaka;
Izumiya, Masashi;
Watanabe, Masatoshi;
Nakagama, Hitoshi

Publication type:

Article

Overexpression of MUC13 is associated with intestinal-type gastric cancer.

Published in:

Cancer Science, 2005, v. 96, n. 5, p. 265, doi. 10.1111/j.1349-7006.2005.00043.x

By:

Shimamura, Takahiro;
Ito, Hirotaka;
Shibahara, Junji;
Watanabe, Akira;
Hippo, Yoshitaka;
Taniguchi, Hirokazu;
Chen, Yongxin;
Kashima, Takeshi;
Ohtomo, Toshihiko;
Tanioka, Fumihiko;
Iwanari, Hiroko;
Kodama, Tatsuhiko;
Kazui, Teruhisa;
Sugimura, Haruhiko;
Fukayama, Masashi;
Aburatani, Hiroyuki

Publication type:

Article

1H, 13C and 15N backbone and side-chain resonance assignments of the human oncogenic protein NCYM.

Published in:

Biomolecular NMR Assignments, 2024, v. 18, n. 1, p. 65, doi. 10.1007/s12104-024-10169-3

By:

Mouhand, Assia;
Nakatani, Kazuma;
Kono, Fumiaki;
Hippo, Yoshitaka;
Matsuo, Tatsuhito;
Barthe, Philippe;
Peters, Judith;
Suenaga, Yusuke;
Tamada, Taro;
Roumestand, Christian

Publication type:

Article

A case of cervical clear cell carcinoma with serous component.

Published in:

Journal of Obstetrics & Gynaecology Research, 2021, v. 47, n. 7, p. 2551, doi. 10.1111/jog.14794

By:

Ebisawa, Keiko;
Sugiyama, Takahiro;
Itami, Makiko;
Maru, Yoshiaki;
Hippo, Yoshitaka;
Tanaka, Naotake

Publication type:

Article

Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance.

Published in:

Frontiers in Oncology, 2024, p. 01, doi. 10.3389/fonc.2024.1237378

By:

Kazuma Nakatani;
Hiroyuki Kogashi;
Takanori Miyamoto;
Taiki Setoguchi;
Tetsushi Sakuma;
Kazuto Kugou;
Yoshinori Hasegawa;
Takashi Yamamoto;
Yoshitaka Hippo;
Yusuke Suenaga

Publication type:

Article

Structural characterization of human de novo protein NCYM and its complex with a newly identified DNA aptamer using atomic force microscopy and small-angle X-ray scattering.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1213678

By:

Seigi Yamamoto;
Fumiaki Kono;
Kazuma Nakatani;
Miwako Hirose;
Katsunori Horii;
Yoshitaka Hippo;
Taro Tamada;
Yusuke Suenaga;
Tatsuhito Matsuo

Publication type:

Article

β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 13, p. 3344, doi. 10.3390/ijms20133344

By:

Aono, Shiori;
Hatanaka, Ayari;
Hatanaka, Atsushi;
Gao, Yue;
Hippo, Yoshitaka;
Taketo, Makoto Mark;
Waku, Tsuyoshi;
Kobayashi, Akira

Publication type:

Article

Kras activation in endometrial organoids drives cellular transformation and epithelial-mesenchymal transition.

Published in:

Oncogenesis, 2021, v. 10, n. 6, p. 1, doi. 10.1038/s41389-021-00337-8

By:

Maru, Yoshiaki;
Tanaka, Naotake;
Tatsumi, Yasutoshi;
Nakamura, Yuki;
Itami, Makiko;
Hippo, Yoshitaka

Publication type:

Article

PGV-1 Causes Disarrangement of Spindle Microtubule Organization Resulting in Aberrant Mitosis in HLF and HuH6 Cells Associated with Altered MYCN Status.

Published in:

Advanced Pharmaceutical Bulletin, 2024, v. 14, n. 3, p. 665, doi. 10.34172/apb.2024.058

By:

Nugraheni, Nadzifa;
Zulfin, Ummi Maryam;
Lestari, Beni;
Hapsari, Novia Permata;
Ikawati, Muthi;
Utomo, Rohmad Yudi;
Suenaga, Yusuke;
Hippo, Yoshitaka;
Meiyanto, Edy

Publication type:

Article

Onset of Quiescence Following p53 Mediated Down- Regulation of H2AX in Normal Cells.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023432

By:

Atsumi, Yuko;
Fujimori, Hiroaki;
Fukuda, Hirokazu;
Inase, Aki;
Shinohe, Keitaro;
Yoshioka, Yoshiko;
Shikanai, Mima;
Ichijima, Yosuke;
Unno, Junya;
Mizutani, Shuki;
Tsuchiya, Naoto;
Hippo, Yoshitaka;
Nakagama, Hitoshi;
Masutani, Mitsuko;
Teraoka, Hirobumi;
Yoshioka, Ken-ichi

Publication type:

Article

Current Status of Patient-Derived Ovarian Cancer Models.

Published in:

Cells (2073-4409), 2019, v. 8, n. 5, p. 505, doi. 10.3390/cells8050505

By:

Maru, Yoshiaki;
Hippo, Yoshitaka

Publication type:

Article

Two-Way Development of the Genetic Model for Endometrial Tumorigenesis in Mice: Current and Future Perspectives.

Published in:

Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.798628

By:

Maru, Yoshiaki;
Hippo, Yoshitaka

Publication type:

Article

Bridging toxicological properties of environmental chemicals between animals and humans using healthy organoid systems.

Published in:

Journal of Toxicological Sciences, 2024, v. 49, n. 10, p. 425, doi. 10.2131/jts.49.425

By:

Toshio Imai;
Rikako Ishigamori;
Mie Naruse;
Masako Ochiai;
Yoshiaki Maru;
Yoshitaka Hippo;
Yukari Totsuka

Publication type:

Article

A high-throughput screening platform to identify MYCN expression inhibitors for liver cancer therapy.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1486671

By:

Xu, Yali;
Mishra, Hricha;
Furutani, Yutaka;
Yanaka, Kaori;
Nishimura, Hajime;
Furuhata, Erina;
Takahashi, Masataka;
Gailhouste, Luc;
Suenaga, Yusuke;
Hippo, Yoshitaka;
Yu, Wenkui;
Matsuura, Tomokazu;
Suzuki, Harukazu;
Qin, Xian-Yang

Publication type:

Article