Works by Hilvo, Mika

Results: 32

A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer.

Published in:

Cancers, 2021, v. 13, n. 8, p. 1764, doi. 10.3390/cancers13081764

By:

Salminen, Liina;
Braicu, Elena Ioana;
Lääperi, Mitja;
Jylhä, Antti;
Oksa, Sinikka;
Hietanen, Sakari;
Sehouli, Jalid;
Kulbe, Hagen;
Bois, Andreas du;
Mahner, Sven;
Harter, Philipp;
Carpén, Olli;
Huhtinen, Kaisa;
Hynninen, Johanna;
Hilvo, Mika;
Bianchi, Fabrizio

Publication type:

Article

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol.

Published in:

European Heart Journal, 2016, v. 37, n. 25, p. 1967, doi. 10.1093/eurheartj/ehw148

By:

Laaksonen, Reijo;
Ekroos, Kim;
Sysi-Aho, Marko;
Hilvo, Mika;
Vihervaara, Terhi;
Kauhanen, Dimple;
Suoniemi, Matti;
Hurme, Reini;
März, Winfried;
Scharnagl, Hubert;
Stojakovic, Tatjana;
Vlachopoulou, Efthymia;
Lokki, Marja-Liisa;
Nieminen, Markku S.;
Klingenberg, Roland;
Matter, Christian M.;
Hornemann, Thorsten;
Jüni, Peter;
Rodondi, Nicolas;
Räber, Lorenz

Publication type:

Article

Ovarian tumours of different histologic type and clinical stage induce similar changes in lipid metabolism.

Published in:

2018

By:

Niemi, Riikka Johanna;
Braicu, Elena Ioana;
Kulbe, Hagen;
Koistinen, Kaisa Maria;
Sehouli, Jalid;
Puistola, Ulla;
Mäenpää, Johanna Unelma;
Hilvo, Mika

Publication type:

journal article

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

Published in:

Journal of Pathology, 2012, v. 226, n. 4, p. 674, doi. 10.1002/path.3956

By:

Lehtinen, Laura;
Vainio, Paula;
Wikman, Harriet;
Reemts, Johannes;
Hilvo, Mika;
Issa, Rana;
Pollari, Sirkku;
Brandt, Burkhard;
Oresic, Matej;
Pantel, Klaus;
Kallioniemi, Olli;
Iljin, Kristiina

Publication type:

Article

Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice.

Published in:

Lipids in Health & Disease, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12944-015-0086-2

By:

Skorve, Jon;
Hilvo, Mika;
Vihervaara, Terhi;
Burri, Lena;
Bohov, Pavol;
Tillander, Veronika;
Bjørndal, Bodil;
Suoniemi, Matti;
Laaksonen, Reijo;
Ekroos, Kim;
Berge, Rolf K.;
Alexson, Stefan E. H.

Publication type:

Article

Remodeling of central metabolism in invasive breast cancer compared to normal breast issue--GC-TOFMS based metabolomics study.

Published in:

BMC Genomics, 2012, v. 13, n. 1, p. 334, doi. 10.1186/1471-2164-13-334

By:

Budczies, Jan;
Denkert, Carsten;
Mï¿½ller, Berit M.;
Brockmï¿½ller, Scarlet F.;
Klauschen, Frederick;
Gyï¿½rffy, Balazs;
Dietel, Manfred;
Richter-Ehrenstein, Christiane;
Marten, Ulrike;
Salek, Reza M.;
Griffin, Julian L.;
Hilvo, Mika;
Orešič, Matej;
Wohlgemuth, Gert;
Fiehn, Oliver

Publication type:

Article

Ceramide stearic to palmitic acid ratio predicts incident diabetes.

Published in:

Diabetologia, 2018, v. 61, n. 6, p. 1424, doi. 10.1007/s00125-018-4590-6

By:

Hilvo, Mika;
Salonurmi, Tuire;
Havulinna, Aki S.;
Kauhanen, Dimple;
Pedersen, Eva Ringdal;
Tell, Grethe S.;
Meyer, Klaus;
Teeriniemi, Anna-Maria;
Laatikainen, Tiina;
Jousilahti, Pekka;
Savolainen, Markku J.;
Nygård, Ottar;
Salomaa, Veikko;
Laaksonen, Reijo

Publication type:

Article

Brain phenotype of carbonic anhydrase IX-deficient mice.

Published in:

Transgenic Research, 2012, v. 21, n. 1, p. 163, doi. 10.1007/s11248-011-9520-z

By:

Pan, Pei-wen;
Parkkila, Anna-Kaisa;
Autio, Salla;
Hilvo, Mika;
Sormunen, Raija;
Pastorekova, Silvia;
Pastorek, Jaromir;
Haapasalo, Hannu;
Parkkila, Seppo

Publication type:

Article

Predictive modeling for identification of older adults with high utilization of health and social services.

Published in:

Scandinavian Journal of Primary Health Care, 2024, v. 42, n. 4, p. 609, doi. 10.1080/02813432.2024.2372297

By:

Sourkatti, Heba;
Pajula, Juha;
Keski-Kuha, Teemu;
Koivisto, Juha;
Hilvo, Mika;
Lähteenmäki, Jaakko

Publication type:

Article

Ceramides and phospholipids in plasma extracellular vesicles are associated with high risk of major cardiovascular events after carotid endarterectomy.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09225-6

By:

Timmerman, Nathalie;
Waissi, Farahnaz;
Dekker, Mirthe;
de Borst, Gert J.;
van Bennekom, Joelle;
de Winter, Robbert J.;
Hilvo, Mika;
Jylhä, Antti;
Pasterkamp, Gerard;
de Kleijn, Dominique P. V.;
Laaksonen, Reijo

Publication type:

Article

Plasma ceramide and phospholipid-based risk score and the risk of cardiovascular death in patients after acute coronary syndrome.

Published in:

European Journal of Preventive Cardiology, 2022, v. 29, n. 6, p. 895, doi. 10.1093/eurjpc/zwaa143

By:

Gencer, Baris;
Morrow, David A;
Braunwald, Eugene;
Goodrich, Erica L;
Hilvo, Mika;
Kauhanen, Dimple;
Sabatine, Marc S;
Laaksonen, Reijo;
O'Donoghue, Michelle L

Publication type:

Article

Prior myocardial infarction, coronary artery disease extent, diabetes mellitus, and CERT2 score for risk stratification in stable coronary artery disease.

Published in:

European Journal of Preventive Cardiology, 2022, v. 29, n. 4, p. e159, doi. 10.1093/eurjpc/zwab122

By:

Hilvo, Mika;
Lääperi, Mitja;
Jylhä, Antti;
Kleber, Marcus E;
Hurme, Reini;
Scharnagl, Hubert;
März, Winfried;
Sinisalo, Juha;
Laaksonen, Reijo

Publication type:

Article

Primary cardiovascular risk prediction by LDL-cholesterol in Caucasian middle-aged and older adults: a joint analysis of three cohorts.

Published in:

European Journal of Preventive Cardiology, 2022, v. 29, n. 3, p. e128, doi. 10.1093/eurjpc/zwab075

By:

Hilvo, Mika;
Dhar, Indu;
Lääperi, Mitja;
Lysne, Vegard;
Sulo, Gehard;
Tell, Grethe S;
Jousilahti, Pekka;
Nygård, Ottar K;
Brenner, Hermann;
Schöttker, Ben;
Laaksonen, Reijo

Publication type:

Article

Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.570628

By:

Hilvo, Mika;
Vasile, Vlad C.;
Donato, Leslie J.;
Hurme, Reini;
Laaksonen, Reijo

Publication type:

Article

A Randomized Controlled Dietary Intervention Improved the Serum Lipid Signature towards a Less Atherogenic Profile in Patients with Rheumatoid Arthritis.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 9, p. 632, doi. 10.3390/metabo11090632

By:

Lindqvist, Helen M.;
Bärebring, Linnea;
Gjertsson, Inger;
Jylhä, Antti;
Laaksonen, Reijo;
Winkvist, Anna;
Hilvo, Mika

Publication type:

Article

Ceramide and phosphatidylcholine lipids‐based risk score predicts major cardiovascular outcomes in patients with heart failure.

Published in:

European Journal of Clinical Investigation, 2025, v. 55, n. 3, p. 1, doi. 10.1111/eci.14359

By:

Witoslawska, Angelika;
Meessen, Jennifer M. T. A.;
Hilvo, Mika;
Jylhä, Antti;
Zannad, Faiez;
Cerrato, Marianna;
Rossignol, Patrick;
Novelli, Deborah;
Duarte, Kevin;
Targher, Giovanni;
Latini, Roberto;
Girerd, Nicolas;
Laaksonen, Reijo

Publication type:

Article

The Novel Ceramide- and Phosphatidylcholine-Based Risk Score for the Prediction of New-Onset of Hypertension.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 24, p. 7524, doi. 10.3390/jcm12247524

By:

Shoghli, Mohammadreza;
Lokki, A. Inkeri;
Lääperi, Mitja;
Sinisalo, Juha;
Lokki, Marja-Liisa;
Hilvo, Mika;
Jylhä, Antti;
Tuomilehto, Jaakko;
Laaksonen, Reijo

Publication type:

Article

Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE<sup>−/−</sup> mice.

Published in:

Scientific Reports, 2017, p. 44503, doi. 10.1038/srep44503

By:

Busnelli, Marco;
Manzini, Stefano;
Hilvo, Mika;
Parolini, Cinzia;
Ganzetti, Giulia S.;
Dellera, Federica;
Ekroos, Kim;
Jänis, Minna;
Escalante-Alcalde, Diana;
Sirtori, Cesare R.;
Laaksonen, Reijo;
Chiesa, Giulia

Publication type:

Article

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.

Published in:

Scientific Reports, 2016, p. 24828, doi. 10.1038/srep24828

By:

Aho, Vilma;
Ollila, Hanna M.;
Kronholm, Erkki;
Bondia-Pons, Isabel;
Soininen, Pasi;
Kangas, Antti J.;
Hilvo, Mika;
Seppälä, Ilkka;
Kettunen, Johannes;
Oikonen, Mervi;
Raitoharju, Emma;
Hyötyläinen, Tuulia;
Kähönen, Mika;
Viikari, Jorma S.A.;
Härmä, Mikko;
Sallinen, Mikael;
Olkkonen, Vesa M.;
Alenius, Harri;
Jauhiainen, Matti;
Paunio, Tiina

Publication type:

Article

Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients.

Published in:

International Journal of Cancer, 2014, v. 134, n. 7, p. 1725, doi. 10.1002/ijc.28491

By:

Hilvo, Mika;
Gade, Stephan;
Hyötyläinen, Tuulia;
Nekljudova, Valentina;
Seppänen‐Laakso, Tuulikki;
Sysi‐Aho, Marko;
Untch, Michael;
Huober, Jens;
Minckwitz, Gunter;
Denkert, Carsten;
Orešič, Matej;
Loibl, Sibylle

Publication type:

Article

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134184

By:

Jørgenrud, Benedicte;
Jalanko, Mikko;
Heliö, Tiina;
Jääskeläinen, Pertti;
Laine, Mika;
Hilvo, Mika;
Nieminen, Markku S.;
Laakso, Markku;
Hyötyläinen, Tuulia;
Orešič, Matej;
Kuusisto, Johanna

Publication type:

Article

The Most Recently Discovered Carbonic Anhydrase, CA XV, Is Expressed in the Thick Ascending Limb of Henle and in the Collecting Ducts of Mouse Kidney.

Published in:

PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009624

By:

Saari, Sina;
Hilvo, Mika;
Pan, Peiwen;
Gros, Gerolf;
Hanke, Nina;
Waheed, Abdul;
Sly, William S.;
Parkkila, Seppo

Publication type:

Article

Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide.

Published in:

Proteins, 2009, v. 74, n. 1, p. 164, doi. 10.1002/prot.22144

By:

Di Fiore, Anna;
Monti, Simona Maria;
Hilvo, Mika;
Parkkila, Seppo;
Romano, Vincenza;
Scaloni, Andrea;
Pedone, Carlo;
Scozzafava, Andrea;
Supuran, Claudiu T.;
De Simone, Giuseppina

Publication type:

Article

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin–carbonic anhydrase.

Published in:

PeerJ, 2017, p. 1, doi. 10.7717/peerj.4128

By:

Patrikainen, Maarit S.;
Tolvanen, Martti E. E.;
Aspatwar, Ashok;
Barker, Harlan R.;
Ortutay, Csaba;
Jänis, Janne;
Laitaoja, Mikko;
Hytönen, Vesa P.;
Azizi, Latifeh;
Manandhar, Prajwol;
Jáger, Edit;
Vullo, Daniela;
Kukkurainen, Sampo;
Hilvo, Mika;
Supuran, Claudiu T.;
Parkkila, Seppo

Publication type:

Article

Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 6, p. 863, doi. 10.3109/14756360903571685

By:

Baranauskienė, Lina;
Hilvo, Mika;
Matulienė, Jurgita;
Golovenko, Dmitrij;
Manakova, Elena;
Dudutienė, Virginija;
Michailovienė, Vilma;
Torresan, Jolanta;
Jachno, Jelena;
Parkkila, Seppo;
Maresca, Alfonso;
Supuran, Claudiu T.;
Gražulis, Saulius;
Matulis, Daumantas

Publication type:

Article

Maternal Elimination Diet and Symptoms of Cow's Milk Allergy in Breastfed Infants.

Published in:

2021

By:

Hilvo, Mika

Publication type:

Letter

Prediction of Residual Risk by Ceramide-Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy.

Published in:

2020

By:

Hilvo, Mika;
Wallentin, Lars;
Lakic, Tatevik Ghukasyan;
Held, Claes;
Kauhanen, Dimple;
Jylhä, Antti;
Lindbäck, Johan;
Siegbahn, Agneta;
Granger, Christopher B.;
Koenig, Wolfgang;
Stewart, Ralph A. H.;
White, Harvey;
Laaksonen, Reijo;
Ghukasyan Lakic, Tatevik;
STABILITY Investigators

Publication type:

journal article

Global transcriptional response to carbonicanhydrase IX deficiency in the mouse stomach.

Published in:

BMC Genomics, 2010, v. 11, p. 397, doi. 10.1186/1471-2164-11-397

By:

Kallio, Heini;
Hilvo, Mika;
Rodriguez, Alejandra;
Lappalainen, Eeva-Helena;
Lappalainen, Anna-Maria;
Parkkila, Seppo

Publication type:

Article

Ceramides and Phosphatidylcholines Associate with Cardiovascular Diseases in the Elderly.

Published in:

Clinical Chemistry, 2022, v. 68, n. 12, p. 1502, doi. 10.1093/clinchem/hvac158

By:

Katajamäki, Taina T.;
Koivula, Marja-Kaisa;
Hilvo, Mika;
Lääperi, Mitja T. A.;
Salminen, Marika J.;
Viljanen, Anna M.;
Heikkilä, Elisa T. M.;
Löppönen, Minna K.;
Isoaho, Raimo E.;
Kivelä, Sirkka-Liisa;
Jylhä, Antti;
Viikari, Laura;
Irjala, Kerttu M.;
Pulkki, Kari J.;
Laaksonen, Reijo M. H.

Publication type:

Article

Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients.

Published in:

European Heart Journal, 2020, v. 41, n. 3, p. 371, doi. 10.1093/eurheartj/ehz387

By:

Hilvo, Mika;
Meikle, Peter J;
Pedersen, Eva Ringdal;
Tell, Grethe S;
Dhar, Indu;
Brenner, Hermann;
Schöttker, Ben;
Lääperi, Mitja;
Kauhanen, Dimple;
Koistinen, Kaisa M;
Jylhä, Antti;
Huynh, Kevin;
Mellett, Natalie A;
Tonkin, Andrew M;
Sullivan, David R;
Simes, John;
Nestel, Paul;
Koenig, Wolfgang;
Rothenbacher, Dietrich;
Nygård, Ottar

Publication type:

Article

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.

Published in:

European Heart Journal, 2018, v. 39, n. 27, p. 2562, doi. 10.1093/eurheartj/ehy319

By:

Ruuth, Maija;
Nguyen, Su Duy;
Vihervaara, Terhi;
Hilvo, Mika;
Laajala, Teemu D;
Kondadi, Pradeep Kumar;
Gisterå, Anton;
Lähteenmäki, Hanna;
Kittilä, Tiia;
Huusko, Jenni

Publication type:

Article

Characterization of the first beta-class carbonicanhydrase from an arthropod (Drosophilamelanogaster) and phylogenetic analysis ofbeta-class carbonic anhydrases in invertebrates.

Published in:

BMC Biochemistry, 2010, v. 11, p. 28, doi. 10.1186/1471-2091-11-28

By:

Syrjänen, Leo;
Tolvanen, Martti;
Hilvo, Mika;
Olatubosun, Ayodeji;
Innocenti, Alessio;
Scozzafava, Andrea;
Leppiniemi, Jenni;
Niederhauser, Barbara;
Hytönen, Vesa P.;
Gorr, Thomas A.;
Parkkila, Seppo;
Supuran, Claudiu T.

Publication type:

Article