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Ceramides and phospholipids in plasma extracellular vesicles are associated with high risk of major cardiovascular events after carotid endarterectomy.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09225-6
By:
- Timmerman, Nathalie;
- Waissi, Farahnaz;
- Dekker, Mirthe;
- de Borst, Gert J.;
- van Bennekom, Joelle;
- de Winter, Robbert J.;
- Hilvo, Mika;
- Jylhä, Antti;
- Pasterkamp, Gerard;
- de Kleijn, Dominique P. V.;
- Laaksonen, Reijo
Publication type:
Article
A Randomized Controlled Dietary Intervention Improved the Serum Lipid Signature towards a Less Atherogenic Profile in Patients with Rheumatoid Arthritis.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 9, p. 632, doi. 10.3390/metabo11090632
By:
- Lindqvist, Helen M.;
- Bärebring, Linnea;
- Gjertsson, Inger;
- Jylhä, Antti;
- Laaksonen, Reijo;
- Winkvist, Anna;
- Hilvo, Mika
Publication type:
Article
15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Published in:
Journal of Pathology, 2012, v. 226, n. 4, p. 674, doi. 10.1002/path.3956
By:
- Lehtinen, Laura;
- Vainio, Paula;
- Wikman, Harriet;
- Reemts, Johannes;
- Hilvo, Mika;
- Issa, Rana;
- Pollari, Sirkku;
- Brandt, Burkhard;
- Oresic, Matej;
- Pantel, Klaus;
- Kallioniemi, Olli;
- Iljin, Kristiina
Publication type:
Article
Characterization of the first beta-class carbonicanhydrase from an arthropod (Drosophilamelanogaster) and phylogenetic analysis ofbeta-class carbonic anhydrases in invertebrates.
Published in:
BMC Biochemistry, 2010, v. 11, p. 28, doi. 10.1186/1471-2091-11-28
By:
- Syrjänen, Leo;
- Tolvanen, Martti;
- Hilvo, Mika;
- Olatubosun, Ayodeji;
- Innocenti, Alessio;
- Scozzafava, Andrea;
- Leppiniemi, Jenni;
- Niederhauser, Barbara;
- Hytönen, Vesa P.;
- Gorr, Thomas A.;
- Parkkila, Seppo;
- Supuran, Claudiu T.
Publication type:
Article
Ceramide stearic to palmitic acid ratio predicts incident diabetes.
Published in:
Diabetologia, 2018, v. 61, n. 6, p. 1424, doi. 10.1007/s00125-018-4590-6
By:
- Hilvo, Mika;
- Salonurmi, Tuire;
- Havulinna, Aki S.;
- Kauhanen, Dimple;
- Pedersen, Eva Ringdal;
- Tell, Grethe S.;
- Meyer, Klaus;
- Teeriniemi, Anna-Maria;
- Laatikainen, Tiina;
- Jousilahti, Pekka;
- Savolainen, Markku J.;
- Nygård, Ottar;
- Salomaa, Veikko;
- Laaksonen, Reijo
Publication type:
Article
Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE<sup>−/−</sup> mice.
Published in:
Scientific Reports, 2017, p. 44503, doi. 10.1038/srep44503
By:
- Busnelli, Marco;
- Manzini, Stefano;
- Hilvo, Mika;
- Parolini, Cinzia;
- Ganzetti, Giulia S.;
- Dellera, Federica;
- Ekroos, Kim;
- Jänis, Minna;
- Escalante-Alcalde, Diana;
- Sirtori, Cesare R.;
- Laaksonen, Reijo;
- Chiesa, Giulia
Publication type:
Article
Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.
Published in:
Scientific Reports, 2016, p. 24828, doi. 10.1038/srep24828
By:
- Aho, Vilma;
- Ollila, Hanna M.;
- Kronholm, Erkki;
- Bondia-Pons, Isabel;
- Soininen, Pasi;
- Kangas, Antti J.;
- Hilvo, Mika;
- Seppälä, Ilkka;
- Kettunen, Johannes;
- Oikonen, Mervi;
- Raitoharju, Emma;
- Hyötyläinen, Tuulia;
- Kähönen, Mika;
- Viikari, Jorma S.A.;
- Härmä, Mikko;
- Sallinen, Mikael;
- Olkkonen, Vesa M.;
- Alenius, Harri;
- Jauhiainen, Matti;
- Paunio, Tiina
Publication type:
Article
Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification.
Published in:
Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.570628
By:
- Hilvo, Mika;
- Vasile, Vlad C.;
- Donato, Leslie J.;
- Hurme, Reini;
- Laaksonen, Reijo
Publication type:
Article
The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134184
By:
- Jørgenrud, Benedicte;
- Jalanko, Mikko;
- Heliö, Tiina;
- Jääskeläinen, Pertti;
- Laine, Mika;
- Hilvo, Mika;
- Nieminen, Markku S.;
- Laakso, Markku;
- Hyötyläinen, Tuulia;
- Orešič, Matej;
- Kuusisto, Johanna
Publication type:
Article
The Most Recently Discovered Carbonic Anhydrase, CA XV, Is Expressed in the Thick Ascending Limb of Henle and in the Collecting Ducts of Mouse Kidney.
Published in:
PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009624
By:
- Saari, Sina;
- Hilvo, Mika;
- Pan, Peiwen;
- Gros, Gerolf;
- Hanke, Nina;
- Waheed, Abdul;
- Sly, William S.;
- Parkkila, Seppo
Publication type:
Article
Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients.
Published in:
European Heart Journal, 2020, v. 41, n. 3, p. 371, doi. 10.1093/eurheartj/ehz387
By:
- Hilvo, Mika;
- Meikle, Peter J;
- Pedersen, Eva Ringdal;
- Tell, Grethe S;
- Dhar, Indu;
- Brenner, Hermann;
- Schöttker, Ben;
- Lääperi, Mitja;
- Kauhanen, Dimple;
- Koistinen, Kaisa M;
- Jylhä, Antti;
- Huynh, Kevin;
- Mellett, Natalie A;
- Tonkin, Andrew M;
- Sullivan, David R;
- Simes, John;
- Nestel, Paul;
- Koenig, Wolfgang;
- Rothenbacher, Dietrich;
- Nygård, Ottar
Publication type:
Article
Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide.
Published in:
Proteins, 2009, v. 74, n. 1, p. 164, doi. 10.1002/prot.22144
By:
- Di Fiore, Anna;
- Monti, Simona Maria;
- Hilvo, Mika;
- Parkkila, Seppo;
- Romano, Vincenza;
- Scaloni, Andrea;
- Pedone, Carlo;
- Scozzafava, Andrea;
- Supuran, Claudiu T.;
- De Simone, Giuseppina
Publication type:
Article
The Novel Ceramide- and Phosphatidylcholine-Based Risk Score for the Prediction of New-Onset of Hypertension.
Published in:
Journal of Clinical Medicine, 2023, v. 12, n. 24, p. 7524, doi. 10.3390/jcm12247524
By:
- Shoghli, Mohammadreza;
- Lokki, A. Inkeri;
- Lääperi, Mitja;
- Sinisalo, Juha;
- Lokki, Marja-Liisa;
- Hilvo, Mika;
- Jylhä, Antti;
- Tuomilehto, Jaakko;
- Laaksonen, Reijo
Publication type:
Article
A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer.
Published in:
Cancers, 2021, v. 13, n. 8, p. 1764, doi. 10.3390/cancers13081764
By:
- Salminen, Liina;
- Braicu, Elena Ioana;
- Lääperi, Mitja;
- Jylhä, Antti;
- Oksa, Sinikka;
- Hietanen, Sakari;
- Sehouli, Jalid;
- Kulbe, Hagen;
- Bois, Andreas du;
- Mahner, Sven;
- Harter, Philipp;
- Carpén, Olli;
- Huhtinen, Kaisa;
- Hynninen, Johanna;
- Hilvo, Mika;
- Bianchi, Fabrizio
Publication type:
Article
Ceramides and Phosphatidylcholines Associate with Cardiovascular Diseases in the Elderly.
Published in:
Clinical Chemistry, 2022, v. 68, n. 12, p. 1502, doi. 10.1093/clinchem/hvac158
By:
- Katajamäki, Taina T.;
- Koivula, Marja-Kaisa;
- Hilvo, Mika;
- Lääperi, Mitja T. A.;
- Salminen, Marika J.;
- Viljanen, Anna M.;
- Heikkilä, Elisa T. M.;
- Löppönen, Minna K.;
- Isoaho, Raimo E.;
- Kivelä, Sirkka-Liisa;
- Jylhä, Antti;
- Viikari, Laura;
- Irjala, Kerttu M.;
- Pulkki, Kari J.;
- Laaksonen, Reijo M. H.
Publication type:
Article
Plasma ceramide and phospholipid-based risk score and the risk of cardiovascular death in patients after acute coronary syndrome.
Published in:
European Journal of Preventive Cardiology, 2022, v. 29, n. 6, p. 895, doi. 10.1093/eurjpc/zwaa143
By:
- Gencer, Baris;
- Morrow, David A;
- Braunwald, Eugene;
- Goodrich, Erica L;
- Hilvo, Mika;
- Kauhanen, Dimple;
- Sabatine, Marc S;
- Laaksonen, Reijo;
- O'Donoghue, Michelle L
Publication type:
Article
Prior myocardial infarction, coronary artery disease extent, diabetes mellitus, and CERT2 score for risk stratification in stable coronary artery disease.
Published in:
European Journal of Preventive Cardiology, 2022, v. 29, n. 4, p. e159, doi. 10.1093/eurjpc/zwab122
By:
- Hilvo, Mika;
- Lääperi, Mitja;
- Jylhä, Antti;
- Kleber, Marcus E;
- Hurme, Reini;
- Scharnagl, Hubert;
- März, Winfried;
- Sinisalo, Juha;
- Laaksonen, Reijo
Publication type:
Article
Primary cardiovascular risk prediction by LDL-cholesterol in Caucasian middle-aged and older adults: a joint analysis of three cohorts.
Published in:
European Journal of Preventive Cardiology, 2022, v. 29, n. 3, p. e128, doi. 10.1093/eurjpc/zwab075
By:
- Hilvo, Mika;
- Dhar, Indu;
- Lääperi, Mitja;
- Lysne, Vegard;
- Sulo, Gehard;
- Tell, Grethe S;
- Jousilahti, Pekka;
- Nygård, Ottar K;
- Brenner, Hermann;
- Schöttker, Ben;
- Laaksonen, Reijo
Publication type:
Article
Ovarian tumours of different histologic type and clinical stage induce similar changes in lipid metabolism.
Published in:
2018
By:
- Niemi, Riikka Johanna;
- Braicu, Elena Ioana;
- Kulbe, Hagen;
- Koistinen, Kaisa Maria;
- Sehouli, Jalid;
- Puistola, Ulla;
- Mäenpää, Johanna Unelma;
- Hilvo, Mika
Publication type:
journal article
Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice.
Published in:
Lipids in Health & Disease, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12944-015-0086-2
By:
- Skorve, Jon;
- Hilvo, Mika;
- Vihervaara, Terhi;
- Burri, Lena;
- Bohov, Pavol;
- Tillander, Veronika;
- Bjørndal, Bodil;
- Suoniemi, Matti;
- Laaksonen, Reijo;
- Ekroos, Kim;
- Berge, Rolf K.;
- Alexson, Stefan E. H.
Publication type:
Article
Maternal Elimination Diet and Symptoms of Cow's Milk Allergy in Breastfed Infants.
Published in:
2021
By:
- Hilvo, Mika
Publication type:
Letter
Prediction of Residual Risk by Ceramide-Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy.
Published in:
2020
By:
- Hilvo, Mika;
- Wallentin, Lars;
- Lakic, Tatevik Ghukasyan;
- Held, Claes;
- Kauhanen, Dimple;
- Jylhä, Antti;
- Lindbäck, Johan;
- Siegbahn, Agneta;
- Granger, Christopher B.;
- Koenig, Wolfgang;
- Stewart, Ralph A. H.;
- White, Harvey;
- Laaksonen, Reijo;
- Ghukasyan Lakic, Tatevik;
- STABILITY Investigators
Publication type:
journal article
Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients.
Published in:
International Journal of Cancer, 2014, v. 134, n. 7, p. 1725, doi. 10.1002/ijc.28491
By:
- Hilvo, Mika;
- Gade, Stephan;
- Hyötyläinen, Tuulia;
- Nekljudova, Valentina;
- Seppänen‐Laakso, Tuulikki;
- Sysi‐Aho, Marko;
- Untch, Michael;
- Huober, Jens;
- Minckwitz, Gunter;
- Denkert, Carsten;
- Orešič, Matej;
- Loibl, Sibylle
Publication type:
Article
Identification and characterization of a novel zebrafish (Danio rerio) pentraxin–carbonic anhydrase.
Published in:
PeerJ, 2017, p. 1, doi. 10.7717/peerj.4128
By:
- Patrikainen, Maarit S.;
- Tolvanen, Martti E. E.;
- Aspatwar, Ashok;
- Barker, Harlan R.;
- Ortutay, Csaba;
- Jänis, Janne;
- Laitaoja, Mikko;
- Hytönen, Vesa P.;
- Azizi, Latifeh;
- Manandhar, Prajwol;
- Jáger, Edit;
- Vullo, Daniela;
- Kukkurainen, Sampo;
- Hilvo, Mika;
- Supuran, Claudiu T.;
- Parkkila, Seppo
Publication type:
Article
Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.
Published in:
European Heart Journal, 2018, v. 39, n. 27, p. 2562, doi. 10.1093/eurheartj/ehy319
By:
- Ruuth, Maija;
- Nguyen, Su Duy;
- Vihervaara, Terhi;
- Hilvo, Mika;
- Laajala, Teemu D;
- Kondadi, Pradeep Kumar;
- Gisterå, Anton;
- Lähteenmäki, Hanna;
- Kittilä, Tiia;
- Huusko, Jenni
Publication type:
Article
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol.
Published in:
European Heart Journal, 2016, v. 37, n. 25, p. 1967, doi. 10.1093/eurheartj/ehw148
By:
- Laaksonen, Reijo;
- Ekroos, Kim;
- Sysi-Aho, Marko;
- Hilvo, Mika;
- Vihervaara, Terhi;
- Kauhanen, Dimple;
- Suoniemi, Matti;
- Hurme, Reini;
- März, Winfried;
- Scharnagl, Hubert;
- Stojakovic, Tatjana;
- Vlachopoulou, Efthymia;
- Lokki, Marja-Liisa;
- Nieminen, Markku S.;
- Klingenberg, Roland;
- Matter, Christian M.;
- Hornemann, Thorsten;
- Jüni, Peter;
- Rodondi, Nicolas;
- Räber, Lorenz
Publication type:
Article
Remodeling of central metabolism in invasive breast cancer compared to normal breast issue--GC-TOFMS based metabolomics study.
Published in:
BMC Genomics, 2012, v. 13, n. 1, p. 334, doi. 10.1186/1471-2164-13-334
By:
- Budczies, Jan;
- Denkert, Carsten;
- Mï¿½ller, Berit M.;
- Brockmï¿½ller, Scarlet F.;
- Klauschen, Frederick;
- Gyï¿½rffy, Balazs;
- Dietel, Manfred;
- Richter-Ehrenstein, Christiane;
- Marten, Ulrike;
- Salek, Reza M.;
- Griffin, Julian L.;
- Hilvo, Mika;
- Orešič, Matej;
- Wohlgemuth, Gert;
- Fiehn, Oliver
Publication type:
Article
Global transcriptional response to carbonicanhydrase IX deficiency in the mouse stomach.
Published in:
BMC Genomics, 2010, v. 11, p. 397, doi. 10.1186/1471-2164-11-397
By:
- Kallio, Heini;
- Hilvo, Mika;
- Rodriguez, Alejandra;
- Lappalainen, Eeva-Helena;
- Lappalainen, Anna-Maria;
- Parkkila, Seppo
Publication type:
Article
Brain phenotype of carbonic anhydrase IX-deficient mice.
Published in:
Transgenic Research, 2012, v. 21, n. 1, p. 163, doi. 10.1007/s11248-011-9520-z
By:
- Pan, Pei-wen;
- Parkkila, Anna-Kaisa;
- Autio, Salla;
- Hilvo, Mika;
- Sormunen, Raija;
- Pastorekova, Silvia;
- Pastorek, Jaromir;
- Haapasalo, Hannu;
- Parkkila, Seppo
Publication type:
Article

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