Works by Hilty, Christian

Results: 35

Protein Folding Studied by Dissolution Dynamic Nuclear Polarization.

Published in:

Angewandte Chemie, 2013, v. 125, n. 35, p. 9362, doi. 10.1002/ange.201301851

By:

Chen, Hsueh ‐ Ying;
Ragavan, Mukundan;
Hilty, Christian

Publication type:

Article

Hyperpolarized Binding Pocket Nuclear Overhauser Effect for Determination of Competitive Ligand Binding.

Published in:

Angewandte Chemie, 2012, v. 124, n. 21, p. 5269, doi. 10.1002/ange.201201003

By:

Lee, Youngbok;
Zeng, Haifeng;
Mazur, Adam;
Wegstroth, Melanie;
Carlomagno, Teresa;
Reese, Marcel;
Lee, Donghan;
Becker, Stefan;
Griesinger, Christian;
Hilty, Christian

Publication type:

Article

Spectrally Resolved Magnetic Resonance Imaging of a Xenon BiosensorThis work was supported by the Director, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division, of the US Department of Energy under Contract No. DE-AC03-76SF00098. C.H. acknowledges support from the Schweizerischer Nationalfonds through a postdoctoral fellowship. T.L. acknowledges support from the University of California Biotechnology Research and Education Program for a training grant.

Published in:

Angewandte Chemie, 2006, v. 118, n. 1, p. 76, doi. 10.1002/ange.200502693

By:

Christian Hilty;
Thomas J. Lowery;
David E. Wemmer;
Alexander Pines

Publication type:

Article

Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase.

Published in:

Journal of Biomolecular NMR, 2016, v. 65, n. 1, p. 41, doi. 10.1007/s10858-016-0037-x

By:

Wang, Yunyi;
Ragavan, Mukundan;
Hilty, Christian

Publication type:

Article

Stereospecific assignments of the isopropyl methyl groups of the membrane protein OmpX in DHPC micelles.

Published in:

Journal of Biomolecular NMR, 2003, v. 27, n. 4, p. 377, doi. 10.1023/A:1025877326533

By:

Hilty, Christian;
Wider, Gerhard;
Fernández, César;
Wüthrich, Kurt

Publication type:

Article

Side chain NMR assignments in the membrane protein OmpX reconstituted in DHPC micelles.

Published in:

Journal of Biomolecular NMR, 2002, v. 23, n. 4, p. 289, doi. 10.1023/A:1020218419190

By:

Hilty, Christian;
Fernández, César;
Wider, Gerhard;
Wüthrich, Kurt

Publication type:

Article

Hyperpolarized water as universal sensitivity booster in biomolecular NMR.

Published in:

Nature Protocols, 2022, v. 17, n. 7, p. 1621, doi. 10.1038/s41596-022-00693-8

By:

Hilty, Christian;
Kurzbach, Dennis;
Frydman, Lucio

Publication type:

Article

Application of Relaxation Dispersion of Hyperpolarized 13C Spins to Protein–Ligand Binding.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 45, p. 24018, doi. 10.1002/anie.202109430

By:

Qi, Chang;
Wang, Yunyi;
Hilty, Christian

Publication type:

Article

Dynamic Nuclear Polarization Enhanced Nuclear Spin Optical Rotation.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 16, p. 8823, doi. 10.1002/anie.202016412

By:

Zhu, Yue;
Hilty, Christian;
Savukov, Igor

Publication type:

Article

Membrane protein dynamics in different environments: simulation study of the outer membrane protein X in a lipid bilayer and in a micelle.

Published in:

European Biophysics Journal, 2011, v. 40, n. 1, p. 39, doi. 10.1007/s00249-010-0626-7

By:

Choutko, Alexandra;
Glättli, Alice;
Fernández, César;
Hilty, Christian;
Wüthrich, Kurt;
Gunsteren, Wilfred

Publication type:

Article

Membrane Protein–Lipid Interactions in Mixed Micelles Studied by NMR Spectroscopy with the Use of Paramagnetic Reagents.

Published in:

ChemBioChem, 2004, v. 5, n. 4, p. 467, doi. 10.1002/cbic.200300815

By:

Christian Hilty;
Gerhard Wider;
César Fernández;
Kurt Wüthrich

Publication type:

Article

Real-Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 25, p. 7070, doi. 10.1002/anie.201700464

By:

Ragavan, Mukundan;
Iconaru, Luigi I.;
Park, Cheon‐Gil;
Kriwacki, Richard W.;
Hilty, Christian

Publication type:

Article

Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 32, p. 9162, doi. 10.1002/anie.201410653

By:

Hilty, Christian;
Boebinger, Gregory S.;
Schwalbe, Harald;
Webb, Andrew;
Comment, Arnaud;
Engelke, Frank;
Griffin, Robert G.;
Parigi, Giacomo;
Ravera, Enrico;
Prisner, Thomas;
van Bentum, Jan;
Vega, Shimon;
Luchinat, Claudio;
Frydman, Lucio;
Edison, Arthur S.;
Griesinger, Christian;
Ardenkjaer-Larsen, Jan-Henrik;
Maeda, Hidaeki;
Duckett, Simon

Publication type:

Article

Affinity Screening Using Competitive Binding with Fluorine-19 Hyperpolarized Ligands.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 16, p. 4941, doi. 10.1002/anie.201411424

By:

Kim, Yaewon;
Hilty, Christian

Publication type:

Article

Nuclear Spin Hyperpolarization of NH2‐ and CH3‐Substituted Pyridine and Pyrimidine Moieties by SABRE.

Published in:

ChemPhysChem, 2020, v. 21, n. 19, p. 2166, doi. 10.1002/cphc.202000483

By:

Mandal, Ratnamala;
Pham, Pierce;
Hilty, Christian

Publication type:

Article

Implementation and Characterization of Flow Injection in Dissolution Dynamic Nuclear Polarization NMR Spectroscopy.

Published in:

ChemPhysChem, 2015, v. 16, n. 12, p. 2646, doi. 10.1002/cphc.201500292

By:

Chen, Hsueh‐Ying;
Hilty, Christian

Publication type:

Article

Characterization of Membrane Protein‐Lipid Interactions in Unfolded OmpX with Enhanced Time Resolution by Hyperpolarized NMR.

Published in:

ChemBioChem, 2020, v. 21, n. 19, p. 2861, doi. 10.1002/cbic.202000271

By:

Kim, Jihyun;
Mandal, Ratnamala;
Hilty, Christian

Publication type:

Article

Polarization Transfer from Ligands Hyperpolarized by Dissolution Dynamic Nuclear Polarization for Screening in Drug Discovery.

Published in:

ChemMedChem, 2015, v. 10, n. 9, p. 1559, doi. 10.1002/cmdc.201500241

By:

Min, Hlaing;
Sekar, Giridhar;
Hilty, Christian

Publication type:

Article

Real-Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy.

Published in:

Angewandte Chemie, 2017, v. 129, n. 25, p. 7176, doi. 10.1002/ange.201700464

By:

Ragavan, Mukundan;
Iconaru, Luigi I.;
Park, Cheon ‐ Gil;
Kriwacki, Richard W.;
Hilty, Christian

Publication type:

Article

Neue Ansätze zur Empfindlichkeitssteigerung in der biomolekularen NMR-Spektroskopie.

Published in:

Angewandte Chemie, 2015, v. 127, n. 32, p. 9292, doi. 10.1002/ange.201410653

By:

Ardenkjaer-Larsen, Jan-Henrik;
Boebinger, Gregory S.;
Comment, Arnaud;
Duckett, Simon;
Edison, Arthur S.;
Engelke, Frank;
Griesinger, Christian;
Griffin, Robert G.;
Hilty, Christian;
Maeda, Hidaeki;
Parigi, Giacomo;
Prisner, Thomas;
Ravera, Enrico;
van Bentum, Jan;
Vega, Shimon;
Webb, Andrew;
Luchinat, Claudio;
Schwalbe, Harald;
Frydman, Lucio

Publication type:

Article

Affinitätsbestimmung durch kompetitive Bindung mit Fluor-19-hyperpolarisierten Liganden.

Published in:

Angewandte Chemie, 2015, v. 127, n. 16, p. 5023, doi. 10.1002/ange.201411424

By:

Kim, Yaewon;
Hilty, Christian

Publication type:

Article

Rapid determination of biosynthetic pathways using fractional isotope enrichment and high-resolution dynamic nuclear polarization enhanced NMR.

Published in:

NMR in Biomedicine, 2011, v. 24, n. 8, p. 1016, doi. 10.1002/nbm.1679

By:

Bowen, Sean;
Sekar, Giridhar;
Hilty, Christian

Publication type:

Article

Protein Folding Studied by Dissolution Dynamic Nuclear Polarization.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 35, p. 9192, doi. 10.1002/anie.201301851

By:

Chen, Hsueh‐Ying;
Ragavan, Mukundan;
Hilty, Christian

Publication type:

Article

Hyperpolarized Binding Pocket Nuclear Overhauser Effect for Determination of Competitive Ligand Binding.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 21, p. 5179, doi. 10.1002/anie.201201003

By:

Lee, Youngbok;
Zeng, Haifeng;
Mazur, Adam;
Wegstroth, Melanie;
Carlomagno, Teresa;
Reese, Marcel;
Lee, Donghan;
Becker, Stefan;
Griesinger, Christian;
Hilty, Christian

Publication type:

Article

Time-Resolved Dynamic Nuclear Polarization Enhanced NMR Spectroscopy.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 28, p. 5235, doi. 10.1002/anie.200801492

By:

Bowen, Sean;
Hilty, Christian

Publication type:

Article

Application of Relaxation Dispersion of Hyperpolarized 13C Spins to Protein–Ligand Binding.

Published in:

Angewandte Chemie, 2021, v. 133, n. 45, p. 24220, doi. 10.1002/ange.202109430

By:

Qi, Chang;
Wang, Yunyi;
Hilty, Christian

Publication type:

Article

Dynamic Nuclear Polarization Enhanced Nuclear Spin Optical Rotation.

Published in:

Angewandte Chemie, 2021, v. 133, n. 16, p. 8905, doi. 10.1002/ange.202016412

By:

Zhu, Yue;
Hilty, Christian;
Savukov, Igor

Publication type:

Article

Ultrafast multidimensional Laplace NMR for a rapid and sensitive chemical analysis.

Published in:

Nature Communications, 2015, v. 6, n. 9, p. 8363, doi. 10.1038/ncomms9363

By:

Ahola, Susanna;
Zhivonitko, Vladimir V;
Mankinen, Otto;
Zhang, Guannan;
Kantola, Anu M.;
Chen, Hsueh-Ying;
Hilty, Christian;
Koptyug, Igor V.;
Telkki, Ville-Veikko

Publication type:

Article

NMR-Solution Structures in Methanol of an a-Heptapeptide, of a 3/2-Nonapeptide, and of an all-3-Icosapeptide Carrying the 20 Proteinogenic Side Chains.

Published in:

Helvetica Chimica Acta, 2005, v. 88, n. 7, p. 1969

By:

Dieter Seebach;
Raveendra 4;I. Mathad;
Thierry Kimmerlin;
Yogesh 4;R. Mahajan;
Pascal Bindschdler;
Magnus Rueping;
Bernhard Jaun;
Christian Hilty;
Touraj Etezady-Esfarjani

Publication type:

Article

NMR-Structural Investigations of a β3-Dodecapeptide with Proteinogenic Side Chains in Methanol and in Aqueous Solutions.

Published in:

Helvetica Chimica Acta, 2002, v. 85, n. 5, p. 1197, doi. 10.1002/1522-2675(200205)85:5<1197::AID-HLCA1197>3.0.CO;2-E

By:

Etezady-Esfarjani, Touraj;
Hilty, Christian;
Wüthrich, Kurt;
Rueping, Magnus;
Schreiber, Jürg;
Seebach, Dieter

Publication type:

Article

Spectrally Resolved Magnetic Resonance Imaging of a Xenon BiosensorThis work was supported by the Director, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division, of the US Department of Energy under Contract No. DE-AC03-76SF00098. C.H. acknowledges support from the Schweizerischer Nationalfonds through a postdoctoral fellowship. T.L. acknowledges support from the University of California Biotechnology Research and Education Program for a training grant.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 1, p. 70, doi. 10.1002/anie.200502693

By:

Christian Hilty;
Thomas J. Lowery;
David E. Wemmer;
Alexander Pines

Publication type:

Article

Folding determinants of disulfide bond forming protein B explored by solution nuclear magnetic resonance spectroscopy.

Published in:

Proteins, 2011, v. 79, n. 5, p. 1365, doi. 10.1002/prot.22877

By:

Hwang, Soyoun;
Hilty, Christian

Publication type:

Article

Applications of dissolution dynamic nuclear polarization in chemistry and biochemistry.

Published in:

Magnetic Resonance in Chemistry, 2018, v. 56, n. 7, p. 566, doi. 10.1002/mrc.4735

By:

Zhang, Guannan;
Hilty, Christian

Publication type:

Article

Calculations of neon nuclear-spin optical rotation, Verdet and hyperfine constants with configuration-interaction many-body perturbation theory.

Published in:

European Physical Journal D (EPJ D), 2019, v. 73, n. 7, p. N.PAG, doi. 10.1140/epjd/e2019-90431-7

By:

Savukov, Igor;
Filin, Dmytro;
Zhu, Yue;
Castro, Rafael;
Hilty, Christian

Publication type:

Article

Time- and site-resolved kinetic NMR for real-time monitoring of off-equilibrium reactions by 2D spectrotemporal correlations.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28304-w

By:

Jaroszewicz, Michael J.;
Liu, Mengxiao;
Kim, Jihyun;
Zhang, Guannan;
Kim, Yaewon;
Hilty, Christian;
Frydman, Lucio

Publication type:

Article

Works by Hilty, Christian

Protein Folding Studied by Dissolution Dynamic Nuclear Polarization.

Hyperpolarized Binding Pocket Nuclear Overhauser Effect for Determination of Competitive Ligand Binding.

Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase.

Stereospecific assignments of the isopropyl methyl groups of the membrane protein OmpX in DHPC micelles.

Side chain NMR assignments in the membrane protein OmpX reconstituted in DHPC micelles.

Hyperpolarized water as universal sensitivity booster in biomolecular NMR.

Application of Relaxation Dispersion of Hyperpolarized <sup>13</sup>C Spins to Protein–Ligand Binding.

Dynamic Nuclear Polarization Enhanced Nuclear Spin Optical Rotation.

Membrane protein dynamics in different environments: simulation study of the outer membrane protein X in a lipid bilayer and in a micelle.

Membrane Protein–Lipid Interactions in Mixed Micelles Studied by NMR Spectroscopy with the Use of Paramagnetic Reagents.

Real-Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy.

Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy.

Affinity Screening Using Competitive Binding with Fluorine-19 Hyperpolarized Ligands.

Nuclear Spin Hyperpolarization of NH<sub>2</sub>‐ and CH<sub>3</sub>‐Substituted Pyridine and Pyrimidine Moieties by SABRE.

Implementation and Characterization of Flow Injection in Dissolution Dynamic Nuclear Polarization NMR Spectroscopy.

Characterization of Membrane Protein‐Lipid Interactions in Unfolded OmpX with Enhanced Time Resolution by Hyperpolarized NMR.

Polarization Transfer from Ligands Hyperpolarized by Dissolution Dynamic Nuclear Polarization for Screening in Drug Discovery.

Real-Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy.

Neue Ansätze zur Empfindlichkeitssteigerung in der biomolekularen NMR-Spektroskopie.

Affinitätsbestimmung durch kompetitive Bindung mit Fluor-19-hyperpolarisierten Liganden.

Rapid determination of biosynthetic pathways using fractional isotope enrichment and high-resolution dynamic nuclear polarization enhanced NMR.

Protein Folding Studied by Dissolution Dynamic Nuclear Polarization.

Hyperpolarized Binding Pocket Nuclear Overhauser Effect for Determination of Competitive Ligand Binding.

Time-Resolved Dynamic Nuclear Polarization Enhanced NMR Spectroscopy.

Application of Relaxation Dispersion of Hyperpolarized <sup>13</sup>C Spins to Protein–Ligand Binding.

Dynamic Nuclear Polarization Enhanced Nuclear Spin Optical Rotation.

Ultrafast multidimensional Laplace NMR for a rapid and sensitive chemical analysis.

NMR-Solution Structures in Methanol of an a-Heptapeptide, of a 3/2-Nonapeptide, and of an all-3-Icosapeptide Carrying the 20 Proteinogenic Side Chains.

NMR-Structural Investigations of a β<sup>3</sup>-Dodecapeptide with Proteinogenic Side Chains in Methanol and in Aqueous Solutions.

Folding determinants of disulfide bond forming protein B explored by solution nuclear magnetic resonance spectroscopy.

Applications of dissolution dynamic nuclear polarization in chemistry and biochemistry.

Calculations of neon nuclear-spin optical rotation, Verdet and hyperfine constants with configuration-interaction many-body perturbation theory.

Time- and site-resolved kinetic NMR for real-time monitoring of off-equilibrium reactions by 2D spectrotemporal correlations.