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Profiling of coronaviral M<sup>pro</sup> and enteroviral 3C<sup>pro</sup> specificity provides a framework for the development of broad‐spectrum antiviral compounds.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 9, p. 1, doi. 10.1002/pro.5139
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- Publication type:
- Article
Acquisition of new protein domains by coronaviruses: analysis of overlapping genes coding for proteins N and 9b in SARS coronavirus.
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- Virus Genes, 2015, v. 50, n. 1, p. 29, doi. 10.1007/s11262-014-1139-8
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- Publication type:
- Article
Processing of the SARS-CoV pp1a/ab nsp7-10 region.
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- Biochemical Journal, 2020, v. 477, n. 5, p. 1009, doi. 10.1042/BCJ20200029
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- Publication type:
- Article
Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer.
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- EMBO Journal, 2006, v. 25, n. 6, p. 1375, doi. 10.1038/sj.emboj.7600969
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- Publication type:
- Article
Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
- Published in:
- 2005
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- Publication type:
- Correction Notice
Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
- Published in:
- 2005
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- Publication type:
- Correction notice
Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
- Published in:
- PLoS Biology, 2005, v. 3, n. 10, p. 1742, doi. 10.1371/journal.pbio.0030324
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- Publication type:
- Article
Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
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- PLoS Biology, 2005, v. 3, n. 9, p. 1, doi. 10.1371/journal.pbio.0030324
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- Publication type:
- Article
An Efficient Method for the Synthesis of Peptide Aldehyde Libraries Employed in the Discovery of Reversible SARS Coronavirus Main Protease (SARS-CoV M.
- Published in:
- ChemBioChem, 2006, v. 7, n. 7, p. 1048, doi. 10.1002/cbic.200500533
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- Publication type:
- Article
From Repurposing to Redesign: Optimization of Boceprevir to Highly Potent Inhibitors of the SARS-CoV-2 Main Protease †.
- Published in:
- Molecules, 2022, v. 27, n. 13, p. 4292, doi. 10.3390/molecules27134292
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- Publication type:
- Article
Synthesis, Structure–Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication.
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- Molecules, 2022, v. 27, n. 3, p. 1052, doi. 10.3390/molecules27031052
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- Publication type:
- Article
Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus.
- Published in:
- SCIENCE CHINA Life Sciences, 2017, v. 60, n. 12, p. 1403, doi. 10.1007/s11427-017-9238-8
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- Publication type:
- Article
The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors.
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- PLoS Pathogens, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.ppat.1002331
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- Publication type:
- Article
Exoerythrocytic Plasmodium Parasites Secrete a Cysteine Protease Inhibitor Involved in Sporozoite Invasion and Capable of Blocking Cell Death of Host Hepatocytes.
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- PLoS Pathogens, 2010, v. 6, n. 3, p. 1, doi. 10.1371/journal.ppat.1000825
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- Publication type:
- Article
The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes.
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- PLoS Pathogens, 2009, v. 5, n. 5, p. 1, doi. 10.1371/journal.ppat.1000428
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- Publication type:
- Article
Protein Engineering: Modifiziertes Hämoglobin als Blutersatzstoff.
- Published in:
- 1992
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- Publication type:
- Other
Coxsackievirus B3 protease 3C: expression, purification, crystallization and preliminary structural insights.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 12, p. 877, doi. 10.1107/S2053230X16018513
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- Publication type:
- Article
Production, crystallization and X-ray diffraction analysis of the protease CT441 from Chlamydia trachomatis.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 12, p. 1454, doi. 10.1107/S2053230X15020518
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- Publication type:
- Article
Sensitized Detection of Inhibitory Fragments and Iterative Development of Non-Peptidic Protease Inhibitors by Dynamic Ligation Screening.
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- Angewandte Chemie International Edition, 2008, v. 47, n. 17, p. 3275, doi. 10.1002/anie.200704594
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- Publication type:
- Article
Architecture and regulation of HtrA-family proteins involved in protein quality control and stress response.
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- Cellular & Molecular Life Sciences, 2013, v. 70, n. 5, p. 761, doi. 10.1007/s00018-012-1076-4
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- Publication type:
- Article
Crystal structure of Mip, a prolylisomerase from Legionella pneumophila.
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- Nature Structural Biology, 2001, v. 8, n. 9, p. 779, doi. 10.1038/nsb0901-779
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- Publication type:
- Article
Peptide bonds revisited.
- Published in:
- Nature Structural Biology, 1998, v. 5, n. 8, p. 676, doi. 10.1038/1368
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- Publication type:
- Article
Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18676-w
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- Publication type:
- Article
The Evolution of Insulin Glargine and its Continuing Contribution to Diabetes Care.
- Published in:
- 2014
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- Publication type:
- Journal Article
RNA-virus proteases counteracting host innate immunity.
- Published in:
- FEBS Letters, 2017, v. 591, n. 20, p. 3190, doi. 10.1002/1873-3468.12827
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- Publication type:
- Article
Structure of the GTPase and GDI domains of FeoB, the ferrous iron transporter of Legionella pneumophila
- Published in:
- FEBS Letters, 2010, v. 584, n. 4, p. 733, doi. 10.1016/j.febslet.2009.12.045
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- Publication type:
- Article
PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus genome.
- Published in:
- BMC Bioinformatics, 2011, v. 12, n. 1, p. 248, doi. 10.1186/1471-2105-12-248
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- Publication type:
- Article
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PL<sup>pro</sup> and M<sup>pro</sup> proteases, and nsp14 guanine N7-methyltransferase.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35907-w
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- Publication type:
- Article
Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragments.
- Published in:
- Nature Communications, 2016, v. 7, n. 9, p. 12761, doi. 10.1038/ncomms12761
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- Publication type:
- Article
Evidence for a Two-Metal-Ion Mechanism in the Cytidyltransferase KdsB, an Enzyme Involved in Lipopolysaccharide Biosynthesis.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023231
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- Publication type:
- Article
From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design.
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- FEBS Journal, 2014, v. 281, n. 18, p. 4085, doi. 10.1111/febs.12936
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- Publication type:
- Article
E-Only Commentaries.
- Published in:
- Integrative Cancer Therapies, 2011, v. 10, n. 3, p. 298, doi. 10.1177/1534735411429233
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- Publication type:
- Article
Chemotherapeutic Effects of Bioassay-Guided Extracts of the American Cockroach, Periplaneta americana.
- Published in:
- Integrative Cancer Therapies, 2011, v. 10, n. 3, p. NP12, doi. 10.1177/1534735411413467
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- Publication type:
- Article
Binding of Insulin to Its Receptor: Towards an Understanding in Three Dimensions.
- Published in:
- ChemBioChem, 2000, v. 1, n. 1, p. 37, doi. 10.1002/1439-7633(20000703)1:1<37::AID-CBIC37>3.0.CO;2-O
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- Publication type:
- Article
Binding of phenol to R.
- Published in:
- Biopolymers, 1999, v. 51, n. 2, p. 165, doi. 10.1002/(SICI)1097-0282(1999)51:2<165::AID-BIP6>3.0.CO;2-X
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- Publication type:
- Article
A method to detect nonproline cis peptide bonds in proteins.
- Published in:
- Biopolymers, 1999, v. 50, n. 5, p. 536, doi. 10.1002/(SICI)1097-0282(19991015)50:5<536::AID-BIP7>3.0.CO;2-1
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- Publication type:
- Article
Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44621-0
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- Publication type:
- Article
Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
- Published in:
- Virologica Sinica (16740769), 2016, v. 31, n. 4, p. 288, doi. 10.1007/s12250-016-3742-4
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- Publication type:
- Article
Molecular mechanisms of severe acute respiratory syndrome (SARS).
- Published in:
- Respiratory Research, 2005, v. 6, p. 8, doi. 10.1186/1465-9921-6-8
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- Publication type:
- Article
Synthesis and antiplasmodial activity of a cysteine protease-inhibiting biotinylated aziridine-2,3-dicarboxylate.
- Published in:
- Biological Chemistry, 2004, v. 385, n. 5, p. 435, doi. 10.1515/BC.2004.050
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- Publication type:
- Article
The PPIase Active Site of Legionella pneumophila Mip Protein Is Involved in the Infection of Eukaryotic Host Cells.
- Published in:
- Biological Chemistry, 2003, v. 384, n. 1, p. 125, doi. 10.1515/BC.2003.013
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- Publication type:
- Article
Cover Picture: Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus NS2B-NS3 Protease (ChemMedChem 2/2013).
- Published in:
- ChemMedChem, 2013, v. 8, n. 2, p. 173, doi. 10.1002/cmdc.201390000
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- Publication type:
- Article
Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus NS2B-NS3 Protease.
- Published in:
- ChemMedChem, 2013, v. 8, n. 2, p. 231, doi. 10.1002/cmdc.201200497
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- Publication type:
- Article
Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs.
- Published in:
- ChemMedChem, 2012, v. 7, n. 9, p. 1527, doi. 10.1002/cmdc.201200155
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- Publication type:
- Article
Book Review: Methods in Enzymology. Vol. 114 and 115. Diffraction Methods for Biological Macromolecules, Edited by H. W. Wyckoff, C. H. W. Hirs, and S. N. Timasheff.
- Published in:
- Angewandte Chemie International Edition, 1987, v. 26, n. 4, p. 367, doi. 10.1002/anie.198703671
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- Publication type:
- Article
Stetter's Complexes are no Intramolecular Inclusion Compounds.
- Published in:
- Angewandte Chemie International Edition, 1982, v. 21, n. 10, p. 787, doi. 10.1002/anie.198207871
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- Publication type:
- Article
Stetter's Complexes are no Intramolecular Inclusion Compounds.
- Published in:
- Angewandte Chemie International Edition, 1982, v. 21, n. S10, p. 1690, doi. 10.1002/anie.198216900
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- Publication type:
- Article
A Ternary Crown Ether 'Supercomplex': X-Ray Structure Analysis of the 1:1:1 Adduct of Dibenzo-[18]-Crown-6, Potassium Iodide, and Thiourea.
- Published in:
- Angewandte Chemie International Edition, 1981, v. 20, n. 12, p. 1045, doi. 10.1002/anie.198110451
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- Publication type:
- Article
Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property.
- Published in:
- Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 1, p. 6, doi. 10.1002/pro.15
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- Publication type:
- Article
The crystal structure of a Cys25 → Ala mutant of human procathepsin S elucidates enzyme-prosequence interactions.
- Published in:
- Protein Science: A Publication of the Protein Society, 2006, v. 15, n. 11, p. 2619, doi. 10.1110/ps.062401806
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- Publication type:
- Article