Works by Hilbi, Hubert

Results: 68

Secretive Bacterial Pathogens and the Secretory Pathway.

Published in:

Traffic, 2012, v. 13, n. 9, p. 1187, doi. 10.1111/j.1600-0854.2012.01344.x

By:

Hilbi, Hubert;
Haas, Albert

Publication type:

Article

Proteome Analysis of Legionella Vacuoles Purified by Magnetic Immunoseparation Reveals Secretory and Endosomal GTPases.

Published in:

Traffic, 2009, v. 10, n. 1, p. 76, doi. 10.1111/j.1600-0854.2008.00851.x

By:

Urwyler, Simon;
Nyfeler, Yves;
Ragaz, Curdin;
Lee, Hookeun;
Mueller, Lukas N.;
Aebersold, Ruedi;
Hilbi, Hubert

Publication type:

Article

Formation of the Legionella Replicative Compartment at the Crossroads of Retrograde Trafficking.

Published in:

Frontiers in Cellular & Infection Microbiology, 2017, p. 1, doi. 10.3389/fcimb.2017.00482

By:

Bärlocher, Kevin;
Welin, Amanda;
Hilbi, Hubert

Publication type:

Article

Dictyostelium lacking the single atlastin homolog Sey1 shows aberrant ER architecture, proteolytic processes and expansion of the Legionella‐containing vacuole.

Published in:

Cellular Microbiology, 2021, v. 23, n. 5, p. 1, doi. 10.1111/cmi.13318

By:

Hüsler, Dario;
Steiner, Bernhard;
Welin, Amanda;
Striednig, Bianca;
Swart, A. Leoni;
Molle, Virginie;
Hilbi, Hubert;
Letourneur, François

Publication type:

Article

Evolution and function of bacterial RCC1 repeat effectors.

Published in:

Cellular Microbiology, 2020, v. 22, n. 10, p. 1, doi. 10.1111/cmi.13246

By:

Swart, Anna Leoni;
Gomez‐Valero, Laura;
Buchrieser, Carmen;
Hilbi, Hubert

Publication type:

Article

Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes.

Published in:

Cellular Microbiology, 2020, v. 22, n. 5, p. 1, doi. 10.1111/cmi.13163

By:

Knobloch, Paulina;
Koliwer‐Brandl, Hendrik;
Arnold, Fabian M.;
Hanna, Nabil;
Gonda, Imre;
Adenau, Sophia;
Personnic, Nicolas;
Barisch, Caroline;
Seeger, Markus A.;
Soldati, Thierry;
Hilbi, Hubert

Publication type:

Article

Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosol.

Published in:

Cellular Microbiology, 2019, v. 21, n. 6, p. N.PAG, doi. 10.1111/cmi.13008

By:

Koliwer‐Brandl, Hendrik;
Knobloch, Paulina;
Barisch, Caroline;
Welin, Amanda;
Hanna, Nabil;
Soldati, Thierry;
Hilbi, Hubert

Publication type:

Article

Formation of a pathogen vacuole according to L egionella pneumophila: how to kill one bird with many stones.

Published in:

Cellular Microbiology, 2015, v. 17, n. 7, p. 935, doi. 10.1111/cmi.12450

By:

Finsel, Ivo;
Hilbi, Hubert

Publication type:

Article

Icm/ Dot-dependent inhibition of phagocyte migration by L egionella is antagonized by a translocated Ran GTPase activator.

Published in:

Cellular Microbiology, 2014, v. 16, n. 7, p. 977, doi. 10.1111/cmi.12258

By:

Simon, Sylvia;
Wagner, Maria A.;
Rothmeier, Eva;
Müller‐Taubenberger, Annette;
Hilbi, Hubert

Publication type:

Article

Functional analysis of novel Rab GTPases identified in the proteome of purified L egionella-containing vacuoles from macrophages.

Published in:

Cellular Microbiology, 2014, v. 16, n. 7, p. 1034, doi. 10.1111/cmi.12256

By:

Hoffmann, Christine;
Finsel, Ivo;
Otto, Andreas;
Pfaffinger, Gudrun;
Rothmeier, Eva;
Hecker, Michael;
Becher, Dörte;
Hilbi, Hubert

Publication type:

Article

The natural alternative: protozoa as cellular models for L egionella infection.

Published in:

Cellular Microbiology, 2014, v. 16, n. 1, p. 15, doi. 10.1111/cmi.12235

By:

Hoffmann, Christine;
Harrison, Christopher F.;
Hilbi, Hubert

Publication type:

Article

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE.

Published in:

Cellular Microbiology, 2009, v. 11, n. 3, p. 442, doi. 10.1111/j.1462-5822.2008.01266.x

By:

Weber, Stefan S.;
Ragaz, Curdin;
Hilbi, Hubert

Publication type:

Article

The Legionella pneumophila phosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole.

Published in:

Cellular Microbiology, 2008, v. 10, n. 12, p. 2416, doi. 10.1111/j.1462-5822.2008.01219.x

By:

Ragaz, Curdin;
Pietsch, Holger;
Urwyler, Simon;
Tiaden, Andr;
Weber, Stefan S.;
Hilbi, Hubert

Publication type:

Article

The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA.

Published in:

Cellular Microbiology, 2007, v. 9, n. 12, p. 2903, doi. 10.1111/j.1462-5822.2007.01005.x

By:

Tiaden, André;
Spirig, Thomas;
Weber, Stefan S.;
Brüggemann, Holger;
Bosshard, Rachel;
Buchrieser, Carmen;
Hilbi, Hubert

Publication type:

Article

Cholesterol is required to trigger caspase-1 activation and macrophage apoptosis after phagosomal escape of Shigella.

Published in:

Cellular Microbiology, 2007, v. 9, n. 1, p. 265, doi. 10.1111/j.1462-5822.2006.00787.x

By:

Schroeder, Gunnar N.;
Hilbi, Hubert

Publication type:

Article

Modulation of phosphoinositide metabolism by pathogenic bacteria.

Published in:

Cellular Microbiology, 2006, v. 8, n. 11, p. 1697, doi. 10.1111/j.1462-5822.2006.00793.x

By:

Hilbi, Hubert

Publication type:

Article

Induction and protective role of antibodies in Legionella pneumophila infection.

Published in:

European Journal of Immunology, 2007, v. 37, n. 12, p. 3414, doi. 10.1002/eji.200737591

By:

Joller, Nicole;
Spörri, Roman;
Hilbi, Hubert;
Oxenius, Annette

Publication type:

Article

Role of the small GTPase Rap1 in signal transduction, cell dynamics and bacterial infection.

Published in:

Small GTPases, 2019, v. 10, n. 5, p. 336, doi. 10.1080/21541248.2017.1331721

By:

Hilbi, Hubert;
Kortholt, Arjan

Publication type:

Article

Beyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infection.

Published in:

Small GTPases, 2014, v. 5, n. 3, p. 1, doi. 10.4161/21541248.2014.972859

By:

Hilbi, Hubert;
Rothmeier, Eva;
Hoffmann, Christine;
Harrison, Christopher F

Publication type:

Article

Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01512-5

By:

Bärlocher, Kevin;
Hutter, Cedric A. J.;
Swart, A. Leoni;
Steiner, Bernhard;
Welin, Amanda;
Hohl, Michael;
Seeger, Markus A.;
Hilbi, Hubert;
Letourneur, François

Publication type:

Article

Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway.

Published in:

PLoS Pathogens, 2015, v. 11, n. 12, p. 1, doi. 10.1371/journal.ppat.1005307

By:

Simon, Sylvia;
Schell, Ursula;
Heuer, Natalie;
Hager, Dominik;
Albers, Michael F.;
Matthias, Jan;
Fahrnbauer, Felix;
Trauner, Dirk;
Eichinger, Ludwig;
Hedberg, Christian;
Hilbi, Hubert

Publication type:

Article

Biosynthesis of the Natural Fluorophore Legioliulin from Legionella.

Published in:

ChemBioChem, 2013, v. 14, n. 12, p. 1415, doi. 10.1002/cbic.201300373

By:

Ahrendt, Tilman;
Miltenberger, Melissa;
Haneburger, Ina;
Kirchner, Ferdinand;
Kronenwerth, Max;
Brachmann, Alexander O.;
Hilbi, Hubert;
Bode, Helge B.

Publication type:

Article

Legionella‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling.

Published in:

EMBO Reports, 2023, v. 24, n. 3, p. 1, doi. 10.15252/embr.202256007

By:

Vormittag, Simone;
Hüsler, Dario;
Haneburger, Ina;
Kroniger, Tobias;
Anand, Aby;
Prantl, Manuel;
Barisch, Caroline;
Maaß, Sandra;
Becher, Dörte;
Letourneur, François;
Hilbi, Hubert

Publication type:

Article

Quorum sensing governs a transmissive Legionella subpopulation at the pathogen vacuole periphery.

Published in:

EMBO Reports, 2021, v. 22, n. 9, p. 1, doi. 10.15252/embr.202152972

By:

Striednig, Bianca;
Lanner, Ulrike;
Niggli, Selina;
Katic, Ana;
Vormittag, Simone;
Brülisauer, Sabrina;
Hochstrasser, Ramon;
Kaech, Andres;
Welin, Amanda;
Flieger, Antje;
Ziegler, Urs;
Schmidt, Alexander;
Hilbi, Hubert;
Personnic, Nicolas

Publication type:

Article

ER remodeling by the large GTPase atlastin promotes vacuolar growth of Legionella pneumophila.

Published in:

EMBO Reports, 2017, v. 18, n. 10, p. 1817, doi. 10.15252/embr.201743903

By:

Steiner, Bernhard;
Swart, Anna Leoni;
Welin, Amanda;
Weber, Stephen;
Personnic, Nicolas;
Kaech, Andres;
Freyre, Christophe;
Ziegler, Urs;
Klemm, Robin W;
Hilbi, Hubert

Publication type:

Article

Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB.

Published in:

EMBO Reports, 2013, v. 14, n. 2, p. 199, doi. 10.1038/embor.2012.211

By:

Mihai Gazdag, Emerich;
Streller, Alexandra;
Haneburger, Ina;
Hilbi, Hubert;
Vetter, Ingrid R;
Goody, Roger S;
Itzen, Aymelt

Publication type:

Article

Phosphoinositides and the Fate of Legionella in Phagocytes.

Published in:

Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.00025

By:

Swart, A. Leoni;
Hilbi, Hubert

Publication type:

Article

Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum.

Published in:

Molecular Microbiology, 2004, v. 51, n. 1, p. 63, doi. 10.1046/j.1365-2958.2003.03826.x

By:

Otto, Grant P.;
Wu, Mary Y.;
Clarke, Margaret;
Lu, Hao;
Anderson, O. Roger;
Hilbi, Hubert;
Shuman, Howard A.;
Kessin, Richard K.

Publication type:

Article

Icm/Dot-dependent upregulation of phagocytosis by Legionella pneumophila.

Published in:

Molecular Microbiology, 2001, v. 42, n. 3, p. 603, doi. 10.1046/j.1365-2958.2001.02645.x

By:

Hilbi, Hubert;
Segal, Gil;
Shuman, Howard A.

Publication type:

Article

Enzymic and genetic basis for bacterial growth on malonate.

Published in:

Molecular Microbiology, 1997, v. 25, n. 1, p. 3, doi. 10.1046/j.1365-2958.1997.4611824.x

By:

Dimroth, Peter;
Hilbi, Hubert

Publication type:

Article

Intra-Species and Inter-Kingdom Signaling of Legionella pneumophila.

Published in:

Frontiers in Microbiology, 2017, v. 8, p. 1, doi. 10.3389/fmicb.2017.00079

By:

Hochstrasser, Ramon;
Hilbi, Hubert

Publication type:

Article

Pathway analysis using <sup>13</sup>C-glycerol and other carbon tracers reveals a bipartite metabolism of Legionella pneumophila.

Published in:

Molecular Microbiology, 2016, v. 100, n. 2, p. 229, doi. 10.1111/mmi.13313

By:

Häuslein, Ina;
Manske, Christian;
Goebel, Werner;
Eisenreich, Wolfgang;
Hilbi, Hubert

Publication type:

Article

The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression of Legionella pneumophila.

Published in:

Molecular Microbiology, 2016, v. 99, n. 4, p. 778, doi. 10.1111/mmi.13265

By:

Schell, Ursula;
Simon, Sylvia;
Sahr, Tobias;
Hager, Dominik;
Albers, Michael F.;
Kessler, Aline;
Fahrnbauer, Felix;
Trauner, Dirk;
Hedberg, Christian;
Buchrieser, Carmen;
Hilbi, Hubert

Publication type:

Article

Phosphorylation signalling through the L egionella quorum sensing histidine kinases LqsS and LqsT converges on the response regulator LqsR.

Published in:

Molecular Microbiology, 2014, v. 92, n. 5, p. 1039, doi. 10.1111/mmi.12612

By:

Schell, Ursula;
Kessler, Aline;
Hilbi, Hubert

Publication type:

Article

Update on Legionnaires’ disease: pathogenesis, epidemiology, detection and control.

Published in:

Molecular Microbiology, 2010, v. 76, n. 1, p. 1, doi. 10.1111/j.1365-2958.2010.07086.x

By:

Hilbi, Hubert;
Jarraud, Sophie;
Hartland, Elizabeth;
Buchrieser, Carmen

Publication type:

Article

Pathogen trafficking pathways and host phosphoinositide metabolism.

Published in:

Molecular Microbiology, 2009, v. 71, n. 6, p. 1341, doi. 10.1111/j.1365-2958.2009.06608.x

By:

Weber, Stefan S.;
Ragaz, Curdin;
Hilbi, Hubert

Publication type:

Article

Quorum sensing modulates the formation of virulent Legionella persisters within infected cells.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13021-8

By:

Personnic, Nicolas;
Striednig, Bianca;
Lezan, Emmanuelle;
Manske, Christian;
Welin, Amanda;
Schmidt, Alexander;
Hilbi, Hubert

Publication type:

Article

Legionella spp. outdoors: colonization, communication and persistence.

Published in:

Environmental Microbiology Reports, 2011, v. 3, n. 3, p. 286, doi. 10.1111/j.1758-2229.2011.00247.x

By:

Hilbi, Hubert;
Hoffmann, Christine;
Harrison, Christopher F.

Publication type:

Article

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection.

Published in:

PLoS Pathogens, 2019, v. 15, n. 2, p. 1, doi. 10.1371/journal.ppat.1007551

By:

Buckley, Catherine M.;
Heath, Victoria L.;
Guého, Aurélie;
Bosmani, Cristina;
Knobloch, Paulina;
Sikakana, Phumzile;
Personnic, Nicolas;
Dove, Stephen K.;
Michell, Robert H.;
Meier, Roger;
Hilbi, Hubert;
Soldati, Thierry;
Insall, Robert H.;
King, Jason S.

Publication type:

Article

Subversion of cell-autonomous immunity and cell migration by Legionella pneumophila effectors.

Published in:

Frontiers in Immunology, 2015, p. 1, doi. 10.3389/fimmu.2015.00447

By:

Simon, Sylvia;
Hilbi, Hubert;
Zamboni, Dario S.;
Amer, Amal O.

Publication type:

Article

Tapping lipid droplets: A rich fat diet of intracellular bacterial pathogens.

Published in:

Molecular Microbiology, 2023, v. 120, n. 2, p. 194, doi. 10.1111/mmi.15120

By:

Hüsler, Dario;
Stauffer, Pia;
Hilbi, Hubert

Publication type:

Article

The structure of the Legionella response regulator LqsR reveals amino acids critical for phosphorylation and dimerization.

Published in:

Molecular Microbiology, 2020, v. 113, n. 6, p. 1070, doi. 10.1111/mmi.14477

By:

Hochstrasser, Ramon;
Hutter, Cedric A. J.;
Arnold, Fabian M.;
Bärlocher, Kevin;
Seeger, Markus A.;
Hilbi, Hubert

Publication type:

Article

The large GTPase atlastin controls ER remodeling around a pathogen vacuole.

Published in:

Communicative & Integrative Biology, 2018, v. 11, n. 2, p. 1, doi. 10.1080/19420889.2018.1440880

By:

Steiner, Bernhard;
Weber, Stephen;
Kaech, Andres;
Ziegler, Urs;
Hilbi, Hubert

Publication type:

Article

Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0181121

By:

Ouertatani-Sakouhi, Hajer;
Kicka, Sébastien;
Chiriano, Gianpaolo;
Harrison, Christopher F.;
Hilbi, Hubert;
Scapozza, Leonardo;
Soldati, Thierry;
Cosson, Pierre

Publication type:

Article

α-Hydroxyketone Synthesis and Sensing by Legionella and Vibrio.

Published in:

Sensors (14248220), 2012, v. 12, n. 3, p. 2899, doi. 10.3390/s120302899

By:

Tiaden, Andr;
Hilbi, Hubert

Publication type:

Article

Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP.

Published in:

PLoS Pathogens, 2025, v. 21, n. 4, p. 1, doi. 10.1371/journal.ppat.1013026

By:

Solger, Franziska;
Rauch, Jonas;
Vormittag, Simone;
Fan, Mingzhen;
Raykov, Lyudmil;
Charki, Paul;
Katic, Ana;
Letourneur, François;
Soldati, Thierry;
Seibel, Jürgen;
Hilbi, Hubert

Publication type:

Article

The large GTPase Sey1/atlastin mediates lipid droplet- and FadL-dependent intracellular fatty acid metabolism of Legionella pneumophila.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85142

By:

Hüsler, Dario;
Stauffer, Pia;
Keller, Bernhard;
Böck, Desirée;
Steiner, Thomas;
Ostrzinski, Anne;
Vormittag, Simone;
Striednig, Bianca;
Swart, A. Leoni;
Letourneur, François;
Maaß, Sandra;
Becher, Dörte;
Eisenreich, Wolfgang;
Pilhofer, Martin;
Hilbi, Hubert

Publication type:

Article

Rapid Icm/Dot T4SS Inactivation Prevents Resuscitation of Heat‐Induced VBNCLegionella pneumophila by Amoebae.

Published in:

Environmental Microbiology, 2025, v. 27, n. 1, p. 1, doi. 10.1111/1462-2920.70035

By:

Schmid, Camille;
Hilbi, Hubert

Publication type:

Article

Migration of Acanthamoeba through Legionella biofilms is regulated by the bacterial Lqs‐LvbR network, effector proteins and the flagellum.

Published in:

Environmental Microbiology, 2022, v. 24, n. 8, p. 3672, doi. 10.1111/1462-2920.16008

By:

Hochstrasser, Ramon;
Michaelis, Sarah;
Brülisauer, Sabrina;
Sura, Thomas;
Fan, Mingzhen;
Maaß, Sandra;
Becher, Dörte;
Hilbi, Hubert

Publication type:

Article

The pleiotropic Legionella transcription factor LvbR links the Lqs and c‐di‐GMP regulatory networks to control biofilm architecture and virulence.

Published in:

Environmental Microbiology, 2019, v. 21, n. 3, p. 1035, doi. 10.1111/1462-2920.14523

By:

Hochstrasser, Ramon;
Kessler, Aline;
Sahr, Tobias;
Simon, Sylvia;
Schell, Ursula;
Gomez‐Valero, Laura;
Buchrieser, Carmen;
Hilbi, Hubert

Publication type:

Article