Works by Hilakivi-Clarke, Leena

Results: 66

SparseIso: a novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data.

Published in:

Bioinformatics, 2018, v. 34, n. 1, p. 56, doi. 10.1093/bioinformatics/btx557

By:

Shi, Xu;
Wang, Xiao;
Wang, Tian-Li;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Xuan, Jianhua

Publication type:

Article

PSSV: a novel pattern-based probabilistic approach for somatic structural variation identification.

Published in:

Bioinformatics, 2017, v. 33, n. 2, p. 177, doi. 10.1093/bioinformatics/btw605

By:

Xi Chen;
Xu Shi;
Hilakivi-Clarke, Leena;
Shajahan-Haq, Ayesha N.;
Clarke, Robert;
Jianhua Xuan

Publication type:

Article

DM-BLD: differential methylation detection using a hierarchical Bayesian model exploiting local dependency.

Published in:

Bioinformatics, 2017, v. 33, n. 2, p. 161, doi. 10.1093/bioinformatics/btw596

By:

Xiao Wang;
Jinghua Gu;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Jianhua Xuan

Publication type:

Article

BMRF-Net: a software tool for identification of protein interaction subnetworks by a bagging Markov random field-based method.

Published in:

2015

By:

Xu Shi;
Barnes, Robert O.;
Li Chen;
Shajahan-Haq, Ayesha N.;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Yue Wang;
Jianhua Xuan

Publication type:

Product Review

DDN: a caBIG® analytical tool for differential network analysis.

Published in:

Bioinformatics, 2011, v. 27, n. 7, p. 1036, doi. 10.1093/bioinformatics/btr052

By:

Zhang, Bai;
Tian, Ye;
Jin, Lu;
Li, Huai;
Shih, Ie-Ming;
Madhavan, Subha;
Clarke, Robert;
Hoffman, Eric P.;
Xuan, Jianhua;
Hilakivi-Clarke, Leena;
Wang, Yue

Publication type:

Article

Breast cancer: dietary and environmental oestrogens.

Published in:

Biologist, 2001, v. 48, n. 1, p. 21

By:

Clarke, Robert;
Hilakivi-Clarke, Leena;
Trock, Bruce

Publication type:

Article

Molecular mechanisms of tamoxifen-associated endometrial cancer (Review).

Published in:

Oncology Letters, 2015, v. 9, n. 4, p. 1495, doi. 10.3892/ol.2015.2962

By:

RONG HU;
HILAKIVI-CLARKE, LEENA;
CLARKE, ROBERT

Publication type:

Article

Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland.

Published in:

Nature Medicine, 2003, v. 9, n. 8, p. 1081, doi. 10.1038/nm902

By:

Johnson, Michael D.;
Kenney, Nicholas;
Stoica, Adriana;
Hilakivi-Clarke, Leena;
Singh, Baljit;
Chepko, Gloria;
Clarke, Robert;
Sholler, Peter F.;
Lirio, Apolonio A.;
Foss, Colby;
Reiter, Ronald;
Trock, Bruce;
Soonmyoung Paik;
Martin, Mary Beth

Publication type:

Article

ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.pcbi.1009203

By:

Chen, Xi;
Neuwald, Andrew F.;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Xuan, Jianhua

Publication type:

Article

Interaction of dietary polyphenols with molecular signaling pathways of antiestrogen resistance: possible role in breast cancer recurrence.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2012, v. 9, n. 2, p. 127, doi. 10.1515/hmbci-2012-0022

By:

Aiyer, Harini S.;
Bouker, Kerrie B.;
Cook, Katherine L.;
Facey, Caroline O.B.;
Hu, Rong;
Schwartz, Jessica L.;
Shajahan, Ayesha N.;
Hilakivi-Clarke, Leena;
Clarke, Robert

Publication type:

Article

Pregnancy hormonal environment and mother's breast cancer risk.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2012, v. 9, n. 1, p. 11, doi. 10.1515/hmbci-2012-0019

By:

Hilakivi-Clarke, Leena;
de Assis, Sonia;
Warri, Anni;
Luoto, Riitta

Publication type:

Article

Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2011, v. 5, n. 1, p. 35, doi. 10.1515/HMBCI.2010.073

By:

Clarke, Robert;
Shajahan, Ayesha N.;
Yue Wang;
Tyson, John J.;
Riggins, Rebecca B.;
Weiner, Louis M.;
Bauman, William T.;
Xuan, Jianhua;
Zhang, Bai;
Facey, Caroline;
Aiyer, Harini;
Cook, Katherine;
Hickman, F. Edward;
Tavassoly, Iman;
Verdugo, Anael;
Chun Chen;
Zwart, Alan;
W&x00E4;rri, Anni;
Hilakivi-Clarke, Leena A.

Publication type:

Article

Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepuberty.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2010, v. 2, n. 2, p. 227, doi. 10.1515/HMBCI.2010.031

By:

Shajahan, Ayesha N.;
Goel, Shruti;
de Assis, Sonia;
Bin Yu;
Clarke, Robert;
Hilakivi-Clarke, Leena

Publication type:

Article

Maternal high fat diet during pregnancy induces similar miRNA changes in F1 generation male germ cells and F3 generation female mammary glands (LB309).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.lb309

By:

Nguyen, Nguyen;
De Assis, Sonia;
Yin, Chao;
Wehrenberg, Bryan;
Hilakivi‐Clarke, Leena

Publication type:

Article

Life‐time genistein consumption alters unfolded protein response in mammary glands and tumors, and prevents antiestrogen resistance in rats (121.5).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.121.5

By:

Zhang, Xiyuan;
Hilakivi‐Clarke, Leena

Publication type:

Article

Effects of tryptophan on depression and aggression in STZ-D mice.

Published in:

1991

By:

Hilakivi-Clarke, Leena A.;
Hilakivi-Clarke, L A

Publication type:

journal article

Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.

Published in:

2017

By:

Hilakivi-Clarke, Leena;
Wãrri, Anni;
Bouker, Kerrie B.;
Xiyuan Zhang;
Cook, Katherine L.;
Lu Jin;
Zwart, Alan;
Nguyen Nguyen;
Rong Hu;
Cruz, M. Idalia;
de Assis, Sonia;
Xiao Wang;
Xuan, Jason;
Yue Wang;
Wehrenberg, Bryan;
Clarke, Robert;
Wärri, Anni;
Zhang, Xiyuan;
Jin, Lu;
Nguyen, Nguyen

Publication type:

journal article

Social Isolation and Breast Cancer.

Published in:

Endocrinology, 2023, v. 164, n. 10, p. 1, doi. 10.1210/endocr/bqad126

By:

Hilakivi-Clarke, Leena;
Andrade, Fabia de Oliveira

Publication type:

Article

Meta-Analysis of Soy Intake and Breast Cancer Risk.

Published in:

JNCI: Journal of the National Cancer Institute, 2006, v. 98, n. 7, p. 459, doi. 10.1093/jnci/djj102

By:

Trock, Bruce J.;
Hilakivi-Clarke, Leena;
Clarke, Robert

Publication type:

Article

Paternal overweight is associated with increased breast cancer risk in daughters in a mouse model.

Published in:

Scientific Reports, 2016, p. 28602, doi. 10.1038/srep28602

By:

Fontelles, Camile Castilho;
Carney, Elissa;
Clarke, Johan;
Nguyen, Nguyen M.;
Yin, Chao;
Jin, Lu;
Cruz, M. Idalia;
Ong, Thomas Prates;
Hilakivi-Clarke, Leena;
de Assis, Sonia

Publication type:

Article

Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats.

Published in:

International Journal of Cancer, 2011, v. 128, n. 1, p. 12, doi. 10.1002/ijc.25313

By:

Nielsen, Tina S.;
Khan, Galam;
Davis, Jennifer;
Michels, Karin B.;
Hilakivi-Clarke, Leena

Publication type:

Article

Pregnancy and Lifestyle: Short- and Long-Term Effects on Mother's and Her Children's Health.

Published in:

Journal of Pregnancy, 2013, p. 1, doi. 10.1155/2013/537526

By:

Luoto, Riitta;
Mottola, Michelle F.;
Hilakivi-Clarke, Leena

Publication type:

Article

CyNetSVM: A Cytoscape App for Cancer Biomarker Identification Using Network Constrained Support Vector Machines.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170482

By:

Shi, Xu;
Banerjee, Sharmi;
Chen, Li;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Xuan, Jianhua

Publication type:

Article

Richard G. Lister: friend, colleague and teacher.

Published in:

Journal of Psychopharmacology, 1991, v. 5, n. 4, p. v, doi. 10.1177/026988119100500404

By:

Durcan, Michael J.;
Hilakivi-Clarke, Leena A.

Publication type:

Article

mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks.

Published in:

BMC Systems Biology, 2013, v. 7, p. 1, doi. 10.1186/1752-0509-7-S5-S4

By:

Xu Shi;
Jinghua Gu;
Xi Chen;
Shajahan, Ayesha;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Jianhua Xuan

Publication type:

Article

Effect of dietary intervention on serum lignan levels in pregnant women - a controlled trial.

Published in:

Reproductive Health, 2010, v. 7, p. 26, doi. 10.1186/1742-4755-7-26

By:

Luoto, Riitta;
Kharazmi, Elham;
Saarinen, Niina M;
Smeds, Annika I;
Mäkelä, Sari;
Fallah, Mahdi;
Raitanen, Jani;
Hilakivi-Clarke, Leena

Publication type:

Article

Effects of maternal dietary exposure to cadmium during pregnancy on mammary cancer risk among female offspring.

Published in:

Journal of Carcinogenesis, 2012, p. 1, doi. 10.4103/1477-3163.114219

By:

Davis, Jennifer;
Khan, Galam;
Martin, Mary Beth;
Hilakivi-Clarke, Leena

Publication type:

Article

Exposures to Synthetic Estrogens at Different Times During the Life, and Their Effect on Breast Cancer Risk.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2013, v. 18, n. 1, p. 25, doi. 10.1007/s10911-013-9274-8

By:

Hilakivi-Clarke, Leena;
Assis, Sonia;
Warri, Anni

Publication type:

Article

Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79603-5

By:

Chen, Xi;
Gu, Jinghua;
Neuwald, Andrew F.;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Xuan, Jianhua

Publication type:

Article

Author Correction: BICORN: An R package for integrative inference of de novo cis-regulatory modules.

Published in:

2020

By:

Chen, Xi;
Gu, Jinghua;
Neuwald, Andrew F.;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Xuan, Jianhua

Publication type:

Correction Notice

BICORN: An R package for integrative inference of de novo cis-regulatory modules.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63043-2

By:

Chen, Xi;
Gu, Jinghua;
Neuwald, Andrew F.;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Xuan, Jianhua

Publication type:

Article

Early Intake Appears to Be the Key to the Proposed Protective Effects of Soy Intake Against Breast Cancer.

Published in:

Nutrition & Cancer, 2009, v. 61, n. 6, p. 792, doi. 10.1080/01635580903285015

By:

Messina, Mark;
Hilakivi-Clarke, Leena

Publication type:

Article

BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency.

Published in:

BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/1471-2164-16-S7-S10

By:

Xu Shi;
Xiao Wang;
Shajahan, Ayesha;
Hilakivi-Clarke, Leena;
Clarke, Robert;
Jianhua Xuan

Publication type:

Article

Point-Counterpoint: Soy Intake for Breast Cancer Patients.

Published in:

Integrative Cancer Therapies, 2002, v. 1, n. 1, p. 90, doi. 10.1177/1534735402001001008

By:

Block, Keith I.;
Constantinou, Andreas;
Hilakivi-Clarke, Leena;
Hughes, Claude;
Tripathy, Debu;
Tice, Jeffrey A.

Publication type:

Article

Alterations in mammary gland development following neonatal exposure to estradiol, transforming growth factor α, and estrogen receptor antagonist ICI 182,780.

Published in:

Journal of Cellular Physiology, 1997, v. 170, n. 3, p. 279, doi. 10.1002/(SICI)1097-4652(199703)170:3<279::AID-JCP9>3.0.CO;2-L

By:

Hilakivi-Clarke, Leena;
Cho, Elizabeth;
Raygada, Margarita;
Kenney, Nicholas

Publication type:

Article

Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis.

Published in:

Cancer Reports, 2022, v. 5, n. 12, p. 1, doi. 10.1002/cnr2.1752

By:

de Oliveira Andrade, Fabia;
Verma, Vivek;
Hilakivi‐Clarke, Leena

Publication type:

Article

Dietary fat intake and gestational weight gain in relation to estradiol and progesterone plasma levels during pregnancy: a longitudinal study in Swedish women.

Published in:

BMC Women's Health, 2009, v. 9, p. 1, doi. 10.1186/1472-6874-9-10

By:

Lof, Marie;
Hilakivi-Clarke, Leena;
Sven, Sandin S.;
De Assis, Sonia;
Wei Yu;
Weiderpass, Elisabete

Publication type:

Article

Pregnancy weight gain and breast cancer risk.

Published in:

BMC Women's Health, 2004, v. 4, p. 7, doi. 10.1186/1472-6874-4-7

By:

Kinnunen, Tarja I.;
Luoto, Riitta;
Gissler, Mika;
Hemminki, Elina;
Hilakivi-Clarke, Leena

Publication type:

Article

Correction to: Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors.

Published in:

Breast Cancer Research & Treatment, 2018, v. 168, n. 2, p. 481, doi. 10.1007/s10549-017-4634-5

By:

Nomura, Sarah J. O.;
Hwang, Yi-Ting;
Gomez, Scarlett Lin;
Fung, Teresa T.;
Yeh, Shu-Lan;
Dash, Chiranjeev;
Allen, Laura;
Philips, Serena;
Hilakivi-Clarke, Leena;
Zheng, Yun-Ling;
Wang, Judy Huei-yu

Publication type:

Article

Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors.

Published in:

Breast Cancer Research & Treatment, 2018, v. 168, n. 2, p. 467, doi. 10.1007/s10549-017-4578-9

By:

Nomura, Sarah J. O.;
Hwang, Yi-Ting;
Gomez, Scarlett Lin;
Fung, Teresa T.;
Yeh, Shu-Lan;
Dash, Chiranjeev;
Allen, Laura;
Philips, Serena;
Hilakivi-Clarke, Leena;
Zheng, Yun-Ling;
Wang, Judy Huei-yu

Publication type:

Article

Alcohol exposure in utero and breast cancer risk later in life.

Published in:

2001

By:

Stevens, Richard G.;
Hilakivi-Clarke, Leena

Publication type:

Letter

Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling.

Published in:

Oncogene, 2003, v. 22, n. 47, p. 7316, doi. 10.1038/sj.onc.1206937

By:

Clarke, Robert;
Liu, Minetta C;
Bouker, Kerrie B;
Gu, Zhiping;
Lee, Richard Y;
Zhu, Yuelin;
Skaar, Todd C;
Gomez, Bianca;
O'Brien, Kerry;
Wang, Yue;
Hilakivi-Clarke, Leena A

Publication type:

Article

Maternal exposure to diethylstilbestrol during pregnancy and increased breast cancer risk in daughters.

Published in:

2014

By:

Hilakivi-Clarke, Leena

Publication type:

journal article

Effects of pre-pregnancy physical activity and maternal BMI on gestational weight gain and birth weight.

Published in:

Acta Obstetricia et Gynecologica Scandinavica, 2008, v. 87, n. 5, p. 524, doi. 10.1080/00016340802012288

By:

Löf, Marie;
Hilakivi-Clarke, Leena;
Sandin, Sven;
Weiderpass, Elisabete

Publication type:

Article

MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer.

Published in:

Molecular Cancer, 2014, v. 13, p. 1, doi. 10.1186/1476-4598-13-239

By:

Shajahan-Haq, Ayesha N.;
Cook, Katherine L.;
Schwartz-Roberts, Jessica L.;
Eltayeb, Ahreej E.;
Demas, Diane M.;
Warri, Anni M.;
Facey, Caroline O. B.;
Hilakivi-Clarke, Leena A.;
Clarke, Robert

Publication type:

Article

Foods may modify responsiveness to cancer immune checkpoint blockers by altering both the gut microbiota and activation of estrogen receptors in immune cells.

Published in:

Frontiers in Microbiomes, 2022, p. 1, doi. 10.3389/frmbi.2022.1049688

By:

Hilakivi-Clarke, Leena;
Verma, Vivek;
McDermott, Maddie;
Koak, Pal;
de Oliveira Andrade, Fabia

Publication type:

Article

Social Isolation Activates Dormant Mammary Tumors, and Modifies Inflammatory and Mitochondrial Metabolic Pathways in the Rat Mammary Gland.

Published in:

Cells (2073-4409), 2023, v. 12, n. 6, p. 961, doi. 10.3390/cells12060961

By:

Andrade, Fabia de Oliveira;
Jin, Lu;
Clarke, Robert;
Wood, Imani;
Dutton, MaryAnn;
Anjorin, Chezaray;
Rubin, Grace;
Gao, Audrey;
Sengupta, Surojeet;
FitzGerald, Kevin;
Hilakivi-Clarke, Leena

Publication type:

Article

Maternal intake of high n-6 polyunsaturated fatty acid diet during pregnancy causes transgenerational increase in mammary cancer risk in mice.

Published in:

2017

By:

Nguyen, Nguyen M.;
de Oliveira Andrade, Fabia;
Lu Jin;
Xiyuan Zhang;
Macon, Madisa;
Cruz, M. Idalia;
Benitez, Carlos;
Wehrenberg, Bryan;
Chao Yin;
Xiao Wang;
Jianhua Xuan;
de Assis, Sonia;
Hilakivi-Clarke, Leena;
Jin, Lu;
Zhang, Xiyuan;
Yin, Chao;
Wang, Xiao;
Xuan, Jianhua

Publication type:

journal article

Paternal programming of breast cancer risk in daughters in a rat model: opposing effects of animal- and plant-based high-fat diets.

Published in:

2016

By:

Fontelles, Camile Castilho;
Guido, Luiza Nicolosi;
Papaléo Rosim, Mariana;
de Oliveira Andrade, Fábia;
Lu Jin;
Inchauspe, Jessica;
Pires, Vanessa Cardoso;
de Castro, Inar Alves;
Hilakivi-Clarke, Leena;
de Assis, Sonia;
Ong, Thomas Prates;
Rosim, Mariana Papaléo;
Andrade, Fábia de Oliveira;
Jin, Lu

Publication type:

journal article

Maternal High n-6 Polyunsaturated Fatty Acid Intake during Pregnancy Increases Voluntary Alcohol Intake and Hypothalamic Estrogen Receptor Alpha and Beta Levels among Female Offspring.

Published in:

Developmental Neuroscience, 2000, v. 22, n. 5/6, p. 488, doi. 10.1159/000017480

By:

Cabanes, Anna;
de Assis, Sonia;
Gustafsson, Jan-Ake;
Hilakivi-Clarke, Leena

Publication type:

Article