Works by Hikaru Seki

Results: 40

Functional specialization of UDP‐glycosyltransferase 73P12 in licorice to produce a sweet triterpenoid saponin, glycyrrhizin.

Published in:

Plant Journal, 2019, v. 99, n. 6, p. 1127, doi. 10.1111/tpj.14409

By:

Nomura, Yuhta;
Seki, Hikaru;
Suzuki, Tomonori;
Ohyama, Kiyoshi;
Mizutani, Masaharu;
Kaku, Tomomi;
Tamura, Keita;
Ono, Eiichiro;
Horikawa, Manabu;
Sudo, Hiroshi;
Hayashi, Hiroaki;
Saito, Kazuki;
Muranaka, Toshiya

Publication type:

Article

Draft genome assembly and annotation of Glycyrrhiza uralensis, a medicinal legume.

Published in:

Plant Journal, 2017, v. 89, n. 2, p. 181, doi. 10.1111/tpj.13385

By:

Mochida, Keiichi;
Sakurai, Tetsuya;
Seki, Hikaru;
Yoshida, Takuhiro;
Takahagi, Kotaro;
Sawai, Satoru;
Uchiyama, Hiroshi;
Muranaka, Toshiya;
Saito, Kazuki

Publication type:

Article

The AMI1 gene family: indole-3-acetamide hydrolase functions in auxin biosynthesis in plants.

Published in:

Journal of Experimental Botany, 2010, v. 61, n. 1, p. 25, doi. 10.1093/jxb/erp292

By:

Mano, Yoshihiro;
Nemoto, Keiichirou;
Suzuki, Masashi;
Seki, Hikaru;
Fujii, Isao;
Muranaka, Toshiya

Publication type:

Article

Production of the bioactive plant‐derived triterpenoid morolic acid in engineered Saccharomyces cerevisiae.

Published in:

Biotechnology & Bioengineering, 2020, v. 117, n. 7, p. 2198, doi. 10.1002/bit.27357

By:

Srisawat, Pisanee;
Yasumoto, Shuhei;
Fukushima, Ery O.;
Robertlee, Jekson;
Seki, Hikaru;
Muranaka, Toshiya

Publication type:

Article

Triterpenoids in aerenchymatous phellem contribute to internal root aeration and waterlogging adaptability in soybeans.

Published in:

New Phytologist, 2023, v. 239, n. 3, p. 936, doi. 10.1111/nph.18975

By:

Takahashi, Hirokazu;
Abo, Chisato;
Suzuki, Hayato;
Romsuk, Jutapat;
Oi, Takao;
Yanagawa, Asako;
Gorai, Tomoka;
Tomisaki, Yukari;
Jitsui, Mana;
Shimamura, Satoshi;
Mori, Hitoshi;
Kaga, Akito;
Ishimoto, Masao;
Seki, Hikaru;
Muranaka, Toshiya;
Nakazono, Mikio

Publication type:

Article

Identification of oxidosqualene cyclases from the medicinal legume tree Bauhinia forficata: a step toward discovering preponderant α‐amyrin‐producing activity.

Published in:

New Phytologist, 2019, v. 224, n. 1, p. 352, doi. 10.1111/nph.16013

By:

Srisawat, Pisanee;
Fukushima, Ery Odette;
Yasumoto, Shuhei;
Robertlee, Jekson;
Suzuki, Hideyuki;
Seki, Hikaru;
Muranaka, Toshiya

Publication type:

Article

Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 ( HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels.

Published in:

Plant Journal, 2004, v. 37, n. 5, p. 750, doi. 10.1111/j.1365-313X.2004.02003.x

By:

Suzuki, Masashi;
Kamide, Yukiko;
Nagata, Noriko;
Seki, Hikaru;
Ohyama, Kiyoshi;
Kato, Hisashi;
Masuda, Kazuo;
Sato, Shusei;
Kato, Tomohiko;
Tabata, Satoshi;
Yoshida, Shigeo;
Muranaka, Toshiya

Publication type:

Article

Novel triterpene oxidizing activity of Arabidopsis thaliana CYP716A subfamily enzymes.

Published in:

FEBS Letters, 2016, v. 590, n. 4, p. 533, doi. 10.1002/1873-3468.12074

By:

Yasumoto, Shuhei;
Fukushima, Ery O.;
Seki, Hikaru;
Muranaka, Toshiya;
Flügge, Ulf‐Ingo

Publication type:

Article

Insights into the diversification of subclade IVa bHLH transcription factors in Fabaceae.

Published in:

BMC Plant Biology, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12870-021-02887-w

By:

Suzuki, Hayato;
Seki, Hikaru;
Muranaka, Toshiya

Publication type:

Article

Lotus japonicus Triterpenoid Profile and Characterization of the CYP716A51 and LjCYP93E1 Genes Involved in Their Biosynthesis In Planta.

Published in:

Plant & Cell Physiology, 2019, v. 60, n. 11, p. 2496, doi. 10.1093/pcp/pcz145

By:

Suzuki, Hayato;
Fukushima, Ery Odette;
Shimizu, Yuko;
Seki, Hikaru;
Fujisawa, Yukiko;
Ishimoto, Masao;
Osakabe, Keishi;
Osakabe, Yuriko;
Muranaka, Toshiya

Publication type:

Article

Cytochrome P450 Monooxygenase CYP716A141 is a Unique β-Amyrin C-16β Oxidase Involved in Triterpenoid Saponin Biosynthesis in Platycodon grandiflorus.

Published in:

Plant & Cell Physiology, 2017, v. 58, n. 5, p. 874, doi. 10.1093/pcp/pcx043

By:

Keita Tamura;
Yuga Teranishi;
Shinya Ueda;
Hideyuki Suzuki;
Noriaki Kawano;
Kayo Yoshimatsu;
Kazuki Saito;
Nobuo Kawahara;
Toshiya Muranaka;
Hikaru Seki

Publication type:

Article

Functional Analysis of Amorpha-4,11-Diene Synthase (ADS) Homologs from Non-Artemisinin-Producing Artemisia Species: The Discovery of Novel Koidzumiol and (+)-α-Bisabolol Synthases.

Published in:

Plant & Cell Physiology, 2016, v. 57, n. 8, p. 1678, doi. 10.1093/pcp/pcw094

By:

Paskorn Muangphrom;
Hikaru Seki;
Munenori Suzuki;
Aya Komori;
Mika Nishiwaki;
Ryota Mikawa;
Ery Odette Fukushima;
Toshiya Muranaka

Publication type:

Article

P450s and UGTs: Key Players in the Structural Diversity of Triterpenoid Saponins.

Published in:

Plant & Cell Physiology, 2015, v. 56, n. 8, p. 1463, doi. 10.1093/pcp/pcv062

By:

Hikaru Seki;
Keita Tamura;
Toshiya Muranaka

Publication type:

Article

Glycyrrhiza uralensis Transcriptome Landscape and Study of Phytochemicals.

Published in:

Plant & Cell Physiology, 2013, v. 54, n. 5, p. 697, doi. 10.1093/pcp/pct057

By:

Ramilowski, Jordan A.;
Sawai, Satoru;
Seki, Hikaru;
Mochida, Keiichi;
Yoshida, Takuhiro;
Sakurai, Tetsuya;
Muranaka, Toshiya;
Saito, Kazuki;
Daub, Carsten O.

Publication type:

Article

Combinatorial Biosynthesis of Legume Natural and Rare Triterpenoids in Engineered Yeast.

Published in:

Plant & Cell Physiology, 2013, v. 54, n. 5, p. 740, doi. 10.1093/pcp/pct015

By:

Fukushima, Ery O.;
Seki, Hikaru;
Sawai, Satoru;
Suzuki, Munenori;
Ohyama, Kiyoshi;
Saito, Kazuki;
Muranaka, Toshiya

Publication type:

Article

CYP716A Subfamily Members are Multifunctional Oxidases in Triterpenoid Biosynthesis.

Published in:

Plant & Cell Physiology, 2011, v. 52, n. 12, p. 2050, doi. 10.1093/pcp/pcr146

By:

Fukushima, Ery O.;
Seki, Hikaru;
Ohyama, Kiyoshi;
Ono, Eiichiro;
Umemoto, Naoyuki;
Mizutani, Masaharu;
Saito, Kazuki;
Muranaka, Toshiya

Publication type:

Article

LOVASTATIN INSENSITIVE 1, a Novel Pentatricopeptide Repeat Protein, is a Potential Regulatory Factor of Isoprenoid Biosynthesis in Arabidopsis.

Published in:

Plant & Cell Physiology, 2007, v. 48, n. 2, p. 322, doi. 10.1093/pcp/pcm005

By:

Keiko Kobayashi;
Masashi Suzuki;
Jianwei Tang;
Noriko Nagata;
Kiyoshi Ohyama;
Hikaru Seki;
Reiko Kiuchi;
Yasuko Kaneko;
Miki Nakazawa;
Minami Matsui;
Shogo Matsumoto;
Shigeo Yoshida;
Toshiya Muranaka

Publication type:

Article

Lanosterol Synthase in Dicotyledonous Plants.

Published in:

Plant & Cell Physiology, 2006, v. 47, n. 5, p. 565, doi. 10.1093/pcp/pcj031

By:

Suzuki, Masashi;
Ting Xiang;
Ohyama, Kiyoshi;
Seki, Hikaru;
Saito, Kazuki;
Muranaka, Toshiya;
Hayashi, Hiroaki;
Katsube, Yuji;
Kushiro, Tetsuo;
Shibuya, Masaaki;
Ebizuka, Yutaka

Publication type:

Article

Functional Analysis of Retrotransposons in Pea.

Published in:

Plant & Cell Physiology, 1999, v. 40, n. 9, p. 933, doi. 10.1093/oxfordjournals.pcp.a029625

By:

Kato, Hidenori;
Sriprasertsak, Permpong;
Seki, Hikaru;
Ichinose, Yuki;
Shiraishi, Tomonori;
Yamada, Tetsuji

Publication type:

Article

Changes in in vivo DNA-protein Interactions in Pea Phenylalanine Ammonia-lyase and Chalcone Synthase Gene Promoter Induced by Fungal Signal Molecules.

Published in:

Plant & Cell Physiology, 1999, v. 40, n. 1, p. 88, doi. 10.1093/oxfordjournals.pcp.a029478

By:

Seki, Hikaru;
Nagasugi, Yumi;
Ichinose, Yuki;
Shiraishi, Tomonori;
Yamada, Tetsuji

Publication type:

Article

Combined Effects of Multiple cis-Acting Elements in Elicitor-Mediated Activation of PSCHS1 Gene.

Published in:

Plant & Cell Physiology, 1997, v. 38, n. 1, p. 96, doi. 10.1093/oxfordjournals.pcp.a029092

By:

Seki, Hikaru;
Ichinose, Yuki;
Ito, Masayuki;
Shiraishi, Tomonori;
Yamada, Tetsuji

Publication type:

Article

Isolation of Artemisia capillaris membrane-bound di-prenyltransferase for phenylpropanoids and redesign of artepillin C in yeast.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0630-0

By:

Munakata, Ryosuke;
Takemura, Tomoya;
Tatsumi, Kanade;
Moriyoshi, Eiko;
Yanagihara, Koki;
Sugiyama, Akifumi;
Suzuki, Hideyuki;
Seki, Hikaru;
Muranaka, Toshiya;
Kawano, Noriaki;
Yoshimatsu, Kayo;
Kawahara, Nobuo;
Yamaura, Takao;
Grosjean, Jérémy;
Bourgaud, Frédéric;
Hehn, Alain;
Yazaki, Kazufumi

Publication type:

Article

Molecular Basis of C-30 Product Regioselectivity of Legume Oxidases Involved in High-Value Triterpenoid Biosynthesis.

Published in:

Frontiers in Plant Science, 2019, v. 10, p. 1, doi. 10.3389/fpls.2019.01520

By:

Fanani, Much Zaenal;
Fukushima, Ery Odette;
Sawai, Satoru;
Tang, Jianwei;
Ishimori, Masato;
Sudo, Hiroshi;
Ohyama, Kiyoshi;
Seki, Hikaru;
Saito, Kazuki;
Muranaka, Toshiya

Publication type:

Article

Sterol Side Chain Reductase 2 Is a Key Enzyme in the Biosynthesis of Cholesterol, the Common Precursor of Toxic Steroidal Glycoalkaloids in Potato.

Published in:

Plant Cell, 2014, v. 26, n. 9, p. 3763, doi. 10.1105/tpc.114.130096

By:

Sawai, Satoru;
Ohyama, Kiyoshi;
Yasumoto, Shuhei;
Seki, Hikaru;
Sakuma, Tetsushi;
Yamamoto, Takashi;
Takebayashi, Yumiko;
Kojima, Mikiko;
Sakakibara, Hitoshi;
Aoki, Toshio;
Muranaka, Toshiya;
Saito, Kazuki;
Umemoto, Naoyuki

Publication type:

Article

Triterpene Functional Genomics in Licorice for Identification of CYP72A154 Involved in the Biosynthesis of Glycyrrhizin.

Published in:

Plant Cell, 2011, v. 23, n. 11, p. 4112, doi. 10.1105/tpc.110.082685

By:

Seki, Hikaru;
Sawai, Satoru;
Ohyama, Kiyoshi;
Mizutani, Masaharu;
Ohnishi, Toshiyuki;
Sudo, Hiroshi;
Fukushima, Ery Odette;
Akashi, Tomoyoshi;
Aoki, Toshio;
Saito, Kazuki;
Muranaka, Toshiya

Publication type:

Article

High-yield bioactive triterpenoid production by heterologous expression in Nicotiana benthamiana using the Tsukuba system.

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.991909

By:

Jutapat Romsuk;
Shuhei Yasumoto;
Fukushima, Ery Odette;
Kenji Miura;
Toshiya Muranaka;
Hikaru Seki

Publication type:

Article

Comparative Analysis of NADPH-Cytochrome P450 Reductases From Legumes for Heterologous Production of Triterpenoids in Transgenic Saccharomyces cerevisiae.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.762546

By:

Istiandari, Pramesti;
Yasumoto, Shuhei;
Srisawat, Pisanee;
Tamura, Keita;
Chikugo, Ayaka;
Suzuki, Hideyuki;
Seki, Hikaru;
Fukushima, Ery Odette;
Muranaka, Toshiya

Publication type:

Article

Comparative functional analysis of CYP71AV1 natural variants reveals an important residue for the successive oxidation of amorpha-4,11-diene

Published in:

FEBS Letters, 2013, v. 587, n. 3, p. 278, doi. 10.1016/j.febslet.2012.11.031

By:

Komori, Aya;
Suzuki, Munenori;
Seki, Hikaru;
Nishizawa, Tomoko;
Meyer, Jacobus Johannes Marion;
Shimizu, Hideaki;
Yokoyama, Shigeyuki;
Muranaka, Toshiya

Publication type:

Article

The NtAMI1 gene functions in cell division of tobacco BY-2 cells in the presence of indole-3-acetamide

Published in:

FEBS Letters, 2009, v. 583, n. 2, p. 487, doi. 10.1016/j.febslet.2008.12.049

By:

Nemoto, Keiichirou;
Hara, Masamitsu;
Suzuki, Masashi;
Seki, Hikaru;
Muranaka, Toshiya;
Mano, Yoshihiro

Publication type:

Article

Plant-derived isoprenoid sweeteners: recent progress in biosynthetic gene discovery and perspectives on microbial production.

Published in:

Bioscience, Biotechnology & Biochemistry, 2018, v. 82, n. 6, p. 927, doi. 10.1080/09168451.2017.1387514

By:

Hikaru Seki;
Keita Tamura;
Toshiya Muranaka

Publication type:

Article

Class I and II NADPHcytochrome P450 reductases exhibit different roles in triterpenoid biosynthesis in Lotus japonicus.

Published in:

Frontiers in Plant Science, 2023, p. 1, doi. 10.3389/fpls.2023.1214602

By:

Istiandari, Pramesti;
Shuhei Yasumoto;
Seki, Hikaru;
Fukushima, Ery Odette;
Toshiya Muranaka

Publication type:

Article

Two Cytochrome P450 Monooxygenases Catalyze Early Hydroxylation Steps in the Potato Steroid Glycoalkaloid Biosynthetic Pathway.

Published in:

Plant Physiology, 2016, v. 171, n. 4, p. 2458, doi. 10.1104/pp.16.00137

By:

Naoyuki Umemoto;
Masaru Nakayasu;
Kiyoshi Ohyama;
Mari Yotsu-Yamashita;
Masaharu Mizutani;
Hikaru Seki;
Kazuki Saito;
Toshiya Muranaka

Publication type:

Article

Chromosome-scale genome assembly of Glycyrrhiza uralensis revealed metabolic gene cluster centred specialized metabolites biosynthesis.

Published in:

DNA Research, 2022, v. 29, n. 6, p. 1, doi. 10.1093/dnares/dsac043

By:

Rai, Amit;
Hirakawa, Hideki;
Rai, Megha;
Shimizu, Yohei;
Shirasawa, Kenta;
Kikuchi, Shinji;
Seki, Hikaru;
Yamazaki, Mami;
Toyoda, Atsushi;
Isobe, Sachiko;
Muranaka, Toshiya;
Saito, Kazuki

Publication type:

Article

Glycyrrhizin Production in Licorice Hairy Roots Based on Metabolic Redirection of Triterpenoid Biosynthetic Pathway by Genome Editing.

Published in:

Plant & Cell Physiology, 2024, v. 65, n. 2, p. 185, doi. 10.1093/pcp/pcad161

By:

Chiyo, Naoki;
Seki, Hikaru;
Kanamoto, Takuya;
Ueda, Hiroshi;
Kojoma, Mareshige;
Muranaka, Toshiya

Publication type:

Article

Allylic Hydroxylation Activity Is a Source of Saponin Chemodiversity in the Genus Glycyrrhiza.

Published in:

Plant & Cell Physiology, 2021, v. 62, n. 2, p. 262, doi. 10.1093/pcp/pcaa173

By:

Fanani, Much Z;
Sawai, Satoru;
Seki, Hikaru;
Ishimori, Masato;
Ohyama, Kiyoshi;
Fukushima, Ery O;
Sudo, Hiroshi;
Saito, Kazuki;
Muranaka, Toshiya

Publication type:

Article

A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19399-0

By:

Chung, Soo Yeon;
Seki, Hikaru;
Fujisawa, Yukiko;
Shimoda, Yoshikazu;
Hiraga, Susumu;
Nomura, Yuhta;
Saito, Kazuki;
Ishimoto, Masao;
Muranaka, Toshiya

Publication type:

Article

Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites.

Published in:

Journal of Natural Medicines, 2016, v. 70, n. 3, p. 318, doi. 10.1007/s11418-016-1008-y

By:

Muangphrom, Paskorn;
Seki, Hikaru;
Fukushima, Ery;
Muranaka, Toshiya

Publication type:

Article

Disruption of a licorice cellulose synthase-derived glycosyltransferase gene demonstrates its in planta role in soyasaponin biosynthesis.

Published in:

Plant Cell Reports, 2024, v. 43, n. 1, p. 1, doi. 10.1007/s00299-023-03095-6

By:

Sakanishi, Manami;
Chung, Soo Yeon;
Fujiwara, Kentaro;
Kojoma, Mareshige;
Muranaka, Toshiya;
Seki, Hikaru

Publication type:

Article

CYP716A179 functions as a triterpene C-28 oxidase in tissue-cultured stolons of Glycyrrhiza uralensis.

Published in:

Plant Cell Reports, 2017, v. 36, n. 3, p. 437, doi. 10.1007/s00299-016-2092-x

By:

Tamura, Keita;
Seki, Hikaru;
Suzuki, Hideyuki;
Kojoma, Mareshige;
Saito, Kazuki;
Muranaka, Toshiya

Publication type:

Article

Functional Characterization of CYP716 Family P450 Enzymes in Triterpenoid Biosynthesis in Tomato.

Published in:

Frontiers in Plant Science, 2017, v. 8, p. 1, doi. 10.3389/fpls.2017.00021

By:

Shuhei Yasumoto;
Hikaru Seki;
Yuko Shimizu;
Fukushima, Ery O.;
Toshiya Muranaka;
Osbourn, Anne;
Miettinen, Karel

Publication type:

Article