Works by Higashi, Richard

Results: 33

An electrophoretic profiling method for thiol-rich phytochelatins and metallothioneins.

Published in:

Phytochemical Analysis, 2004, v. 15, n. 3, p. 175, doi. 10.1002/pca.765

By:

Fan, Teresa W-M.;
Lane, Andrew N.;
Higashi, Richard M.

Publication type:

Article

Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05414

By:

Jian-Guo Ren;
Seth, Pankaj;
Clish, Clary B.;
Lorkiewicz, Pawel K.;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W.-M.;
Sukhatme, Vikas P.

Publication type:

Article

Anaerobic nitrate and ammonium metabolism in flood tolerant rice coleoptiles.

Published in:

Journal of Experimental Botany, 1997, v. 48, n. 314, p. 1655, doi. 10.1093/jxb/48.9.1655

By:

Fan, Teresa W.-M.;
Higashi, Richard M.;
Frenkiel, Thomas A.;
Lane, Andrew N.

Publication type:

Article

Interactive effects of salinity, nitrogen and sulphur on the organic solutes in Spartina alterniflora leaf blades.

Published in:

Journal of Experimental Botany, 1996, v. 47, n. 3, p. 369, doi. 10.1093/jxb/47.3.369

By:

Colmer, Timothy D.;
Teresa W-M., Fan;
Läuchli, André;
Higashi, Richard M.

Publication type:

Article

Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes.

Published in:

2019

By:

Sellers, Katherine;
Allen, Thaddeus D.;
Bousamra II, Michael;
Tan, JinLian;
Méndez-Lucas, Andrés;
Lin, Wei;
Bah, Nourdine;
Chernyavskaya, Yelena;
MacRae, James I.;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W.-M.;
Yuneva, Mariia O.;
Bousamra, Michael 2nd

Publication type:

journal article

Pyruvate carboxylase is critical for non--small-cell lung cancer proliferation.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 687, doi. 10.1172/JCI72873

By:

Sellers, Katherine;
Fox, Matthew P.;
Bousamra II, Michael;
Slone, Stephen P.;
Higashi, Richard M.;
Miller, Donald M.;
Yali Wang;
Yan, Jun;
Yuneva, Mariia O.;
Deshpande, Rahul;
Lane, Andrew N.;
Fan, Teresa W.-M.

Publication type:

Article

Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 7, p. 774, doi. 10.3390/metabo13070774

By:

Fan, Teresa W.-M.;
Winnike, Jason;
Al-Attar, Ahmad;
Belshoff, Alexander C.;
Lorkiewicz, Pawel K.;
Tan, Jin Lian;
Wu, Min;
Higashi, Richard M.;
Lane, Andrew N.

Publication type:

Article

A Micro-Scale Analytical Method for Determining Glycogen Turnover by NMR and FTMS.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 8, p. 760, doi. 10.3390/metabo12080760

By:

Scott, Timothy L.;
Zhu, Juan;
Cassel, Teresa A.;
Vicente-Muñoz, Sara;
Lin, Penghui;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W.-M.

Publication type:

Article

NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 4, p. 202, doi. 10.3390/metabo11040202

By:

Lin, Penghui;
Dai, Li;
Crooks, Daniel R.;
Neckers, Leonard M.;
Higashi, Richard M.;
Fan, Teresa W-M.;
Lane, Andrew N.

Publication type:

Article

Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective.

Published in:

Metabolites (2218-1989), 2020, v. 10, n. 6, p. 249, doi. 10.3390/metabo10060249

By:

Fan, Teresa W. -M.;
Higashi, Richard M.;
Chernayavskaya, Yelena;
Lane, Andrew N.

Publication type:

Article

Inhibition of Anaplerotic Glutaminolysis Underlies Selenite Toxicity in Human Lung Cancer.

Published in:

Proteomics, 2019, v. 19, n. 21/22, p. N.PAG, doi. 10.1002/pmic.201800486

By:

Bruntz, Ronald C.;
Belshoff, Alex C.;
Zhang, Yan;
Macedo, Jessica K. A.;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W.‐M.

Publication type:

Article

Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by 1H-detected 15N nuclear magnetic resonance.

Published in:

Magnetic Resonance in Chemistry, 2015, v. 53, n. 5, p. 337, doi. 10.1002/mrc.4199

By:

Lane, Andrew N.;
Arumugam, Sengodagounder;
Lorkiewicz, Pawel K.;
Higashi, Richard M.;
Laulhé, Sébastien;
Nantz, Michael H.;
Moseley, Hunter N.B.;
Fan, Teresa W.‐M.

Publication type:

Article

6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.67476

By:

Daneshmandi, Saeed;
Cassel, Teresa;
Higashi, Richard M.;
Fan, Teresa W.-M.;
Seth, Pankaj

Publication type:

Article

Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.69578

By:

Fan, Teresa W. M.;
Higashi, Richard M.;
Huan Song;
Daneshmandi, Saeed;
Mahan, Angela L.;
Purdom, Matthew S.;
Bocklage, Therese J.;
Pittman, Thomas A.;
Daheng He;
Chi Wang;
Lane, Andrew N.

Publication type:

Article

Selenium toxicity to survival and reproduction of Collembola and Enchytraeids in a sandy loam soil.

Published in:

Environmental Toxicology & Chemistry, 2018, v. 37, n. 3, p. 846, doi. 10.1002/etc.4017

By:

Kuperman, Roman G.;
Checkai, Ronald T.;
Simini, Michael;
Phillips, Carlton T.;
Higashi, Richard M.;
Fan, Teresa W.‐M.;
Sappington, Keith

Publication type:

Article

Stable isotope-resolved metabolomics analyses of metabolic phenotypes reveal variable glutamine metabolism in different patient-derived models of non-small cell lung cancer from a single patient.

Published in:

Metabolomics, 2024, v. 20, n. 4, p. 1, doi. 10.1007/s11306-024-02126-x

By:

Kinslow, Connor J.;
ll, Michael Bousamra;
Cai, Yihua;
Yan, Jun;
Lorkiewicz, Pawel K.;
Al-Attar, Ahmad;
Tan, Jinlian;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W-M.

Publication type:

Article

Towards quality assurance and quality control in untargeted metabolomics studies.

Published in:

Metabolomics, 2019, v. 15, n. 1, p. 1, doi. 10.1007/s11306-018-1460-7

By:

Beger, Richard D.;
Dunn, Warwick B.;
Bandukwala, Abbas;
Bethan, Bianca;
Broadhurst, David;
Clish, Clary B.;
Dasari, Surendra;
Derr, Leslie;
Evans, Annie;
Fischer, Steve;
Flynn, Thomas;
Hartung, Thomas;
Herrington, David;
Higashi, Richard;
Hsu, Ping-Ching;
Jones, Christina;
Kachman, Maureen;
Karuso, Helen;
Kruppa, Gary;
Lippa, Katrice

Publication type:

Article

New methods to identify high peak density artifacts in Fourier transform mass spectra and to mitigate their effects on high-throughput metabolomic data analysis.

Published in:

Metabolomics, 2018, v. 14, n. 10, p. 1, doi. 10.1007/s11306-018-1426-9

By:

Mitchell, Joshua M.;
Flight, Robert M.;
Wang, Qing Jun;
Higashi, Richard M.;
Fan, Teresa W.-M.;
Lane, Andrew N.;
Moseley, Hunter N. B.

Publication type:

Article

A carbonyl capture approach for profiling oxidized metabolites in cell extracts.

Published in:

Metabolomics, 2012, v. 8, n. 6, p. 989, doi. 10.1007/s11306-011-0395-z

By:

Mattingly, Stephanie;
Xu, Tao;
Nantz, Michael;
Higashi, Richard;
Fan, Teresa

Publication type:

Article

High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS.

Published in:

Metabolomics, 2012, v. 8, n. 5, p. 930, doi. 10.1007/s11306-011-0388-y

By:

Lorkiewicz, Pawel;
Higashi, Richard;
Lane, Andrew;
Fan, Teresa

Publication type:

Article

Stable isotope resolved metabolomics of lung cancer in a SCID mouse model.

Published in:

Metabolomics, 2011, v. 7, n. 2, p. 257, doi. 10.1007/s11306-010-0249-0

By:

Fan, Teresa W. M.;
Lane, Andrew N.;
Higashi, Richard M.;
Jun Yan

Publication type:

Article

Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions.

Published in:

Metabolomics, 2010, v. 6, n. 2, p. 165, doi. 10.1007/s11306-010-0208-9

By:

Fan, Teresa W.-M.;
Peixiong Yuan;
Lane, Andrew N.;
Higashi, Richard M.;
Yun Wang;
Hamidi, Anahita B.;
Rulun Zhou;
Guitart, Xavier;
Guang Chen;
Manji, Husseini K.;
Kaddurah-Daouk, Rima

Publication type:

Article

Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47096-9

By:

Daneshmandi, Saeed;
Jee Eun Choi;
Qi Yan;
MacDonald, Cameron R.;
Pandey, Manu;
Goruganthu, Mounika;
Roberts, Nathan;
Singh, Prashant K.;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W-M.;
Jianmin Wang;
McCarthy, Philip L.;
Repasky, Elizabeth A.;
Mohammadpour, Hemn

Publication type:

Article

Interactive effects of Ca2+ and NaCl salinity on the ionic relations and proline accumulation in the primary root tip of Sorghum bicolor.

Published in:

Physiologia Plantarum, 1996, v. 97, n. 3, p. 421, doi. 10.1111/j.1399-3054.1996.tb00498.x

By:

Colmer, Timothy D.;
Teresa W.-M.Fan, Timothy D.;
Higashi, Richard M.;
Läuchli, André

Publication type:

Article

Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 1, p. D463, doi. 10.1093/nar/gkv1042

By:

Sud, Manish;
Fahy, Eoin;
Cotter, Dawn;
Azam, Kenan;
Vadivelu, Ilango;
Burant, Charles;
Edison, Arthur;
Fiehn, Oliver;
Higashi, Richard;
Nair, K. Sreekumaran;
Sumner, Susan;
Subramaniam, Shankar

Publication type:

Article

Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic networktracing.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01518-z

By:

Sun, Ramon C.;
Fan, Teresa W.-M.;
Pan Deng;
Higashi, Richard M.;
Lane, Andrew N.;
Anh-Thu Le;
Scott, Timothy L.;
Qiushi Sun;
Warmoes, Marc O.;
Ye Yang

Publication type:

Article

Stable isotope-assisted metabolomics in cancer research.

Published in:

IUBMB Life, 2008, v. 60, n. 2, p. 124, doi. 10.1002/iub.17

By:

Lane, Andrew N.;
Fan, Teresa W.-M.;
Higashi, Richard M.

Publication type:

Article

Integrating Metabolomics and Transcriptomics for Probing Se Anticancer Mechanisms*.

Published in:

Drug Metabolism Reviews, 2006, v. 38, n. 4, p. 707, doi. 10.1080/03602530600959599

By:

Fan, Teresa W.-M.;
Higashi, Richard M.;
Lane, Andrew N.

Publication type:

Article

Challenges of Spatially Resolved Metabolism in Cancer Research.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 7, p. 383, doi. 10.3390/metabo14070383

By:

Lane, Andrew N.;
Higashi, Richard M.;
Fan, Teresa W-M.

Publication type:

Article

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on 13C mass isotopologue profiles under non-steady-state conditions.

Published in:

BMC Biology, 2012, v. 10, n. 1, p. 74, doi. 10.1186/1741-7007-10-74

By:

Moseley, Hunter N.B.;
Lane, Andrew N.;
Belshoff, Alex C.;
Higashi, Richard M.;
Fan, Teresa W.M.

Publication type:

Article

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on 13C mass isotopologue profiles under non-steady-state conditions.

Published in:

BMC Biology, 2011, v. 9, n. 1, p. 37, doi. 10.1186/1741-7007-9-37

By:

Moseley, Hunter N. B.;
Lane, Andrew N.;
Belshoff, Alex C.;
Higashi, Richard M.;
Fan, Teresa W. M.

Publication type:

Article

Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 18, p. 4371, doi. 10.1007/s00216-014-7810-z

By:

Gori, Sadakatali;
Lorkiewicz, Pawel;
Ehringer, Daniel;
Belshoff, Alex;
Higashi, Richard;
Fan, Teresa;
Nantz, Michael

Publication type:

Article

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14433-7

By:

Palmieri, Erika M.;
Gonzalez-Cotto, Marieli;
Baseler, Walter A.;
Davies, Luke C.;
Ghesquière, Bart;
Maio, Nunziata;
Rice, Christopher M.;
Rouault, Tracey A.;
Cassel, Teresa;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W.-M.;
Wink, David A.;
McVicar, Daniel W.

Publication type:

Article

Works by Higashi, Richard

An electrophoretic profiling method for thiol-rich phytochelatins and metallothioneins.

Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling.

Anaerobic nitrate and ammonium metabolism in flood tolerant rice coleoptiles.

Interactive effects of salinity, nitrogen and sulphur on the organic solutes in Spartina alterniflora leaf blades.

Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes.

Pyruvate carboxylase is critical for non--small-cell lung cancer proliferation.

Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.

A Micro-Scale Analytical Method for Determining Glycogen Turnover by NMR and FTMS.

NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics.

Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective.

Inhibition of Anaplerotic Glutaminolysis Underlies Selenite Toxicity in Human Lung Cancer.

Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by <sup>1</sup>H-detected <sup>15</sup>N nuclear magnetic resonance.

6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function.

Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues.

Selenium toxicity to survival and reproduction of Collembola and Enchytraeids in a sandy loam soil.

Stable isotope-resolved metabolomics analyses of metabolic phenotypes reveal variable glutamine metabolism in different patient-derived models of non-small cell lung cancer from a single patient.

Towards quality assurance and quality control in untargeted metabolomics studies.

New methods to identify high peak density artifacts in Fourier transform mass spectra and to mitigate their effects on high-throughput metabolomic data analysis.

A carbonyl capture approach for profiling oxidized metabolites in cell extracts.

High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS.

Stable isotope resolved metabolomics of lung cancer in a SCID mouse model.

Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions.

Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies.

Interactive effects of Ca<sup>2+</sup> and NaCl salinity on the ionic relations and proline accumulation in the primary root tip of Sorghum bicolor.

Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools.

Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic networktracing.

Stable isotope-assisted metabolomics in cancer research.

Integrating Metabolomics and Transcriptomics for Probing Se Anticancer Mechanisms*.

Challenges of Spatially Resolved Metabolism in Cancer Research.

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on <sup>13</sup>C mass isotopologue profiles under non-steady-state conditions.

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on <sup>13</sup>C mass isotopologue profiles under non-steady-state conditions.

Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry.

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.