Works matching AU Heyer, Wolf-Dietrich

Results: 47

Moving forward one step back at a time: reversibility during homologous recombination.

Published in:

Current Genetics, 2019, v. 65, n. 6, p. 1333, doi. 10.1007/s00294-019-00995-7

By:

Piazza, Aurèle;
Heyer, Wolf-Dietrich

Publication type:

Article

Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins.

Published in:

EMBO Journal, 1997, v. 16, n. 9, p. 2535, doi. 10.1093/emboj/16.9.2535

By:

Clever, Beate;
Interthal, Heidrun;
Schmuckli-Maurer, Jacqueline;
King, Jeff;
Sigrist, Markus;
Heyer, Wolf-Dietrich

Publication type:

Article

Reconstitution of recombination-associated DNA synthesis with human proteins.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 9, p. 4913, doi. 10.1093/nar/gkt192

By:

Sneeden, Jessica L.;
Grossi, Sara M.;
Tappin, Inger;
Hurwitz, Jerard;
Heyer, Wolf-Dietrich

Publication type:

Article

A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 7, p. 2302, doi. 10.1093/nar/gkp1222

By:

Janke, Ryan;
Herzberg, Kristina;
Rolfsmeier, Michael;
Mar, Jordan;
Bashkirov, Vladimir I.;
Haghnazari, Edwin;
Cantin, Greg;
Yates, John R.;
Heyer, Wolf-Dietrich

Publication type:

Article

A junction branch point adjacent to a DNA backbone nick directs substrate cleavage by Saccharomyces cerevisiae Mus81-Mms4.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 6, p. 2026, doi. 10.1093/nar/gkp038

By:

Ehmsen, Kirk Tevebaugh;
Heyer, Wolf-Dietrich

Publication type:

Article

RAD54 controls access to the invading 3′-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 2, p. 638, doi. 10.1093/nar/gkn980

By:

Li, Xuan;
Heyer, Wolf-Dietrich

Publication type:

Article

Loop 2 in Saccharomyces cerevisiae Rad51 protein regulates filament formation and ATPase activity.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 1, p. 158, doi. 10.1093/nar/gkn914

By:

Zhang, Xiao-Ping;
Galkin, Vitold E.;
Yu, Xiong;
Egelman, Edward H.;
Heyer, Wolf-Dietrich

Publication type:

Article

Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease.

Published in:

Nucleic Acids Research, 2008, v. 36, n. 7, p. 2182, doi. 10.1093/nar/gkm1152

By:

Ehmsen, Kirk Tevebaugh;
Heyer, Wolf-Dietrich

Publication type:

Article

Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 12, p. 4124

By:

Li, Xuan;
Zhang, Xiao-Ping;
Solinger, Jachen A.;
Kiianitsa, Konstantin;
Yu, Xiong;
Egelman, Edward H.;
Heyer, Wolf-Dietrich

Publication type:

Article

Rad54: the Swiss Army knife of homologous recombination?

Published in:

Nucleic Acids Research, 2006, v. 34, n. 15, p. 4115, doi. 10.1093/nar/gkl481

By:

Heyer, Wolf-Dietrich;
Li, Xuan;
Rolfsmeier, Michael;
Zhang, Xiao-Ping

Publication type:

Article

The DNA damage checkpoint pathways exert multiple controls on the efficiency and outcome of the repair of a double-stranded DNA gap.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 14, p. 4257, doi. 10.1093/nar/gkh717

By:

Haghnazari, Edwin;
Heyer, Wolf-Dietrich

Publication type:

Article

Genome instability in rad54 mutants of Saccharomyces cerevisiae.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 3, p. 1013

By:

Schmuckli‐Maurer, Jacqueline;
Rolfsmeier, Michael;
Nguyen, Ho;
Heyer, Wolf‐Dietrich

Publication type:

Article

Spontaneous and double-strand break-induced recombination, and gene conversion tract lengths, are differentially affected by overexpression of wild-type or ATPase-defective yeast Rad54.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 13, p. 2727, doi. 10.1093/nar/gkf413

By:

Kim, Perry M.;
Paffett, Kimberly S.;
Solinger, Jachen A.;
Heyer, Wolf-Dietrich;
Nickoloff, Jac A.

Publication type:

Article

Specific negative effects resulting from elevated levels of the recombinational repair protein Rad54p in Saccharomyces cerevisiae.

Published in:

Yeast, 1999, v. 15, n. 9, p. 721, doi. 10.1002/(SICI)1097-0061(19990630)15:9<721::AID-YEA414>3.0.CO;2-W

By:

Clever, Beate;
Schmuckli-Maurer, Jacqueline;
Sigrist, Markus;
Glassner, Brian J.;
Heyer, Wolf-Dietrich

Publication type:

Article

Guardians of the Genome: BRCA2 and Its Partners.

Published in:

Genes, 2021, v. 12, n. 8, p. 1229, doi. 10.3390/genes12081229

By:

Le, Hang Phuong;
Heyer, Wolf-Dietrich;
Liu, Jie

Publication type:

Article

Bisulfite treatment and single-molecule real-time sequencing reveal D-loop length, position, and distribution.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.59111

By:

Shah, Shanaya Shital;
Hartono, Stella R.;
Chedin, Frederic;
Heyer, Wolf-Dietrich

Publication type:

Article

Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.59112

By:

Shah, Shanaya Shital;
Hartono, Stella;
Piazza, Aurele;
Som, Vanessa;
Wright, William;
Chedin, Frederic;
Heyer, Wolf-Dietrich

Publication type:

Article

Multi-step control of homologous recombination via Mec1/ATR suppresses chromosomal rearrangements.

Published in:

EMBO Journal, 2024, v. 43, n. 14, p. 3027, doi. 10.1038/s44318-024-00139-9

By:

Xie, Bokun;
Sanford, Ethan James;
Hung, Shih-Hsun;
Wagner, Mateusz;
Heyer, Wolf-Dietrich;
Smolka, Marcus B

Publication type:

Article

Multi‐Invasion‐Induced Rearrangements as a Pathway for Physiological and Pathological Recombination.

Published in:

BioEssays, 2018, v. 40, n. 5, p. 1, doi. 10.1002/bies.201700249

By:

Piazza, Aurèle;
Heyer, Wolf‐Dietrich

Publication type:

Article

Mus81-Mms4 Functions as a Single Heterodimer To Cleave Nicked Intermediates in Recombinational DNA Repair.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 15, p. 3065, doi. 10.1128/MCB.00547-12

By:

Schwartz, Erin K.;
Wright, William D.;
Ehmsen, Kirk T.;
Evans, James E.;
Stahlberg, Henning;
Heyer, Wolf-Dietrich

Publication type:

Article

Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 9, p. 1592, doi. 10.1128/MCB.00111-12

By:

Muñoz-Galván, Sandra;
Tous, Cristina;
Blanco, Miguel G.;
Schwartz, Erin K.;
Ehmsen, Kirk T.;
West, Stephen C.;
Heyer, Wolf-Dietrich;
Aguilera, Andrés

Publication type:

Article

Phosphorylation of Rad55 on Serines 2, 8, and 14 Is Required for Efficient Homologous Recombination in the Recovery of Stalled Replication Forks.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 22, p. 15, doi. 10.1128/MCB.01317-06

By:

Herzberg, Kristina;
Bashkirov, Vladimir I.;
Rolfsmeier, Michael;
Haghnazari, Edwin;
McDonald, Hayes;
Anderson, Scott;
Bashkirova, Elena V.;
Yates III, John R.;
Heyer, Wolf-Dietrich

Publication type:

Article

Synthetic Lethality between Gene Defects Affecting a Single Non-essential Molecular Pathway with Reversible Steps.

Published in:

PLoS Computational Biology, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pcbi.1003016

By:

Zinovyev, Andrei;
Kuperstein, Inna;
Barillot, Emmanuel;
Heyer, Wolf-Dietrich

Publication type:

Article

DNA-damage induction of RAD54 can be regulated independently of the RAD9- and DDC1-dependent checkpoints that regulate RNR2.

Published in:

Current Genetics, 2002, v. 41, n. 4, p. 232, doi. 10.1007/s00294-002-0302-2

By:

Walsh, Lindsey;
Schmuckli-Maurer, Jacqueline;
Billinton, Nicholas;
Barker, M. Gordon;
Heyer, Wolf-Dietrich;
Walmsley, Richard M.

Publication type:

Article

Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 4, p. 1, doi. 10.1093/nar/gkaf081

By:

Hung, Shih-Hsun;
Liang, Yuan;
Heyer, Wolf-Dietrich

Publication type:

Article

Local structural dynamics of Rad51 protomers revealed by cryo-electron microscopy of Rad51-ssDNA filaments.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 3, p. 1, doi. 10.1093/nar/gkaf052

By:

Liu, Jie;
Gore, Steven K;
Heyer, Wolf-Dietrich

Publication type:

Article

Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 11, p. 5547, doi. 10.1093/nar/gkad281

By:

Cerqueira, Paula G;
Meyer, Damon;
Zhang, Lilin;
Mallory, Benjamin;
Liu, Jie;
Hua Fu, Becky Xu;
Zhang, Xiaoping;
Heyer, Wolf-Dietrich

Publication type:

Article

DSS1 and ssDNA regulate oligomerization of BRCA2.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 14, p. 7818, doi. 10.1093/nar/gkaa555

By:

Le, Hang Phuong;
Ma, Xiaoyan;
Vaquero, Jorge;
Brinkmeyer, Megan;
Guo, Fei;
Heyer, Wolf-Dietrich;
Liu, Jie

Publication type:

Article

Strand displacement synthesis by yeast DNA polymerase ε.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 17, p. 8229, doi. 10.1093/nar/gkw556

By:

Ganai, Rais A.;
Xiao-Ping Zhang;
Heyer, Wolf-Dietrich;
Johansson, Erik

Publication type:

Article

Nonsense-mediated decay regulates key components of homologous recombination.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 11, p. 5218, doi. 10.1093/nar/gkw182

By:

Janke, Ryan;
Kong, Jeremy;
Braberg, Hannes;
Cantin, Greg;
Yates III, John R.;
Krogan, Nevan J.;
Heyer, Wolf-Dietrich

Publication type:

Article

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 6, p. 3180, doi. 10.1093/nar/gkv175

By:

Mason, Jennifer M.;
Dusad, Kritika;
Wright, William Douglass;
Grubb, Jennifer;
Budke, Brian;
Heyer, Wolf-Dietrich;
Connell, Philip P.;
Weichselbaum, Ralph R.;
Bishop, Douglas K.

Publication type:

Article

The Mus81-Mms4 structure-selective endonuclease requires nicked DNA junctions to undergo conformational changes and bend its DNA substrates for cleavage.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 10, p. 6511, doi. 10.1093/nar/gku265

By:

Mukherjee, Sucheta;
Wright, William Douglass;
Ehmsen, Kirk Tevebaugh;
Heyer, Wolf-Dietrich

Publication type:

Article

The Mus81‐Mms4 structure‐selective endonuclease undergoes nicked junction‐induced conformational changes to bend its DNA substrates for cleavage (553.1).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.553.1

By:

Mukherjee, Sucheta;
Wright, William;
Ehmsen, Kirk;
Heyer, Wolf‐Dietrich

Publication type:

Article

Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cells.

Published in:

PLoS Genetics, 2020, v. 16, n. 5, p. 1, doi. 10.1371/journal.pgen.1008816

By:

Schwartz, Erin K.;
Hung, Shih-Hsun;
Meyer, Damon;
Piazza, Aurèle;
Yan, Kevin;
Fu, Becky Xu Hua;
Heyer, Wolf-Dietrich

Publication type:

Article

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1260, doi. 10.1038/nsmb.1904

By:

Jie Liu;
Doty, Tammy;
Gibson, Bryan;
Heyer, Wolf-Dietrich

Publication type:

Article

A new deal for Holliday junctions.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 2, p. 117, doi. 10.1038/nsmb0204-117

By:

Heyer, Wolf-Dietrich

Publication type:

Article

A Conserved Sequence Extending Motif III of the Motor Domain in the Snf2-Family DNA Translocase Rad54 Is Critical for ATPase Activity.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082184

By:

Zhang, Xiao-Ping;
Janke, Ryan;
Kingsley, James;
Luo, Jerry;
Fasching, Clare;
Ehmsen, Kirk T.;
Heyer, Wolf-Dietrich

Publication type:

Article

Homologous recombination in DNA repair and DNA damage tolerance.

Published in:

Cell Research, 2008, v. 18, n. 1, p. 99, doi. 10.1038/cr.2008.1

By:

Li, Xuan;
Heyer, Wolf-Dietrich

Publication type:

Article

No mutagenic or recombinogenic effects of mobile phone fields at 900 MHz detected in the yeast Saccharomyces cerevisiae.

Published in:

Bioelectromagnetics, 2000, v. 21, n. 7, p. 515, doi. 10.1002/1521-186X(200010)21:7<515::AID-BEM5>3.0.CO;2-K

By:

Gos, Pascal;
Eicher, Bernhard;
Kohli, Jürg;
Heyer, Wolf-Dietrich

Publication type:

Article

Extremely high frequency electromagnetic fields at low power density do not affect the division of exponential phase Saccharomyces cerevisiae cells.

Published in:

Bioelectromagnetics, 1997, v. 18, n. 2, p. 142, doi. 10.1002/(SICI)1521-186X(1997)18:2<142::AID-BEM7>3.0.CO;2-2

By:

Gos, Pascal;
Eicher, Bernhard;
Kohli, Jürg;
Heyer, Wolf-Dietrich

Publication type:

Article

Rad51 paralogues Rad55-Rad57 balance the antirecombinase Srs2 in Rad51 filament formation.

Published in:

Nature, 2011, v. 479, n. 7372, p. 245, doi. 10.1038/nature10522

By:

Liu, Jie;
Renault, Ludovic;
Veaute, Xavier;
Fabre, Francis;
Stahlberg, Henning;
Heyer, Wolf-Dietrich

Publication type:

Article

Turning end-joining upside down in mitosis.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 6, p. 1, doi. 10.1080/23723556.2021.2007029

By:

Llorens-Agost, Marta;
Ensminger, Michael;
Le, Hang Phuong;
Heyer, Wolf-Dietrich;
Löbrich, Markus

Publication type:

Article

Role of the Srs2--Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae.

Published in:

Genetics, 2019, v. 212, n. 4, p. 1133, doi. 10.1534/genetics.119.302337

By:

Jenkins, Shirin S.;
Gore, Steven;
Xiaoge Guo;
Jie Liu;
Ede, Christopher;
Veaute, Xavier;
Jinks-Robertson, Sue;
Kowalczykowski, Stephen C.;
Heyer, Wolf-Dietrich

Publication type:

Article

Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase d-extending D-loops.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.22195

By:

Jie Liu;
Ede, Christopher;
Wright, William D.;
Gore, Steven K.;
Jenkins, Shirin S.;
Freudenthal, Bret D.;
Washington, M. Todd;
Veaute, Xavier;
Heyer, Wolf-Dietrich

Publication type:

Article

Presynaptic filament dynamics in homologous recombination and DNA repair.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2011, v. 46, n. 3, p. 240, doi. 10.3109/10409238.2011.576007

By:

Liu, Jie;
Ehmsen, Kirk T.;
Heyer, Wolf-Dietrich;
Morrical, Scott W.

Publication type:

Article

Direct Kinase-to-Kinase Signaling Mediated by the FHA Phosphoprotein Recognition Domain of the Dun1 DNA Damage Checkpoint Kinase.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 4, p. 1441, doi. 10.1128/MCB.23.4.1441-1452.2003

By:

Bashkirov, Vladimir I.;
Bashkirova, Elena V.;
Haghnazari, Edwin;
Heyer, Wolf-Dietrich

Publication type:

Article

In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12082-z

By:

Tavares, Eliana Moreira;
Wright, William Douglass;
Heyer, Wolf-Dietrich;
Le Cam, Eric;
Dupaigne, Pauline

Publication type:

Article